Published in J Biol Chem on November 27, 2006
The signaling mechanisms of syndecan heparan sulfate proteoglycans. Curr Opin Cell Biol (2009) 1.53
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RhoE Is required for keratinocyte differentiation and stratification. Mol Biol Cell (2008) 1.05
Heparan sulfate chain valency controls syndecan-4 function in cell adhesion. J Biol Chem (2010) 1.02
Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion. Int J Biochem Cell Biol (2008) 1.01
Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration. J Biol Chem (2012) 0.96
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J Cell Sci (2009) 0.95
The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells. BMC Cancer (2009) 0.95
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Melanocortin 1 receptor regulates melanoma cell migration by controlling syndecan-2 expression. J Biol Chem (2012) 0.85
Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci (2013) 0.84
Heparan sulfate proteoglycans and their binding proteins in embryo implantation and placentation. Semin Cell Dev Biol (2007) 0.83
Molecular docking of heparin oligosaccharides with Hep-II heparin-binding domain of fibronectin reveals an interplay between the different positions of sulfate groups. Glycoconj J (2013) 0.79
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ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Sci Rep (2016) 0.75
RhoGDI: multiple functions in the regulation of Rho family GTPase activities. Biochem J (2005) 2.50
The Rho kinases I and II regulate different aspects of myosin II activity. J Cell Biol (2005) 2.16
Syndecans in wound healing, inflammation and vascular biology. Int J Biochem Cell Biol (2006) 2.05
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
Proteoglycans in health and disease: the multiple roles of syndecan shedding. FEBS J (2010) 1.58
Fibronectin matrix assembly requires distinct contributions from Rho kinases I and -II. Mol Biol Cell (2006) 1.54
VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J Biol Chem (2005) 1.53
Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. Biochem J (2006) 1.48
Cellular roles of ADAM12 in health and disease. Int J Biochem Cell Biol (2008) 1.46
A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase. J Biol Chem (2004) 1.42
PKCbeta-dependent activation of RhoA by syndecan-4 during focal adhesion formation. J Cell Sci (2006) 1.38
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. J Biol Chem (2003) 1.36
Syndecans as receptors and organizers of the extracellular matrix. Cell Tissue Res (2009) 1.27
Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans. Matrix Biol (2003) 1.24
Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells. Stem Cells (2007) 1.23
Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms. J Biol Chem (2008) 1.19
Syndecans as cell surface receptors: Unique structure equates with functional diversity. Matrix Biol (2010) 1.16
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. J Biol Chem (2002) 1.16
Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. J Mol Biol (2005) 1.14
Distribution and clinical significance of heparan sulfate proteoglycans in ovarian cancer. Clin Cancer Res (2004) 1.13
Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J Biol Chem (2010) 1.13
The CMV early enhancer/chicken beta actin (CAG) promoter can be used to drive transgene expression during the differentiation of murine embryonic stem cells into vascular progenitors. BMC Cell Biol (2008) 1.12
Altered glycosylation of recombinant NKp30 hampers binding to heparan sulfate: a lesson for the use of recombinant immunoreceptors as an immunological tool. Glycobiology (2007) 1.12
Perlecan and tumor angiogenesis. J Histochem Cytochem (2003) 1.09
Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation. J Cell Sci (2007) 1.08
Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes. J Biol Chem (2005) 1.08
Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. J Biol Chem (2007) 1.08
Syndecan-4 associates with alpha-actinin. J Biol Chem (2002) 1.07
Palmitoylation at Cys574 is essential for MT1-MMP to promote cell migration. FASEB J (2005) 1.07
On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. J Biol Chem (2012) 1.04
Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46. Biochemistry (2005) 1.03
A conserved NXIP motif is required for cell adhesion properties of the syndecan-4 ectodomain. J Biol Chem (2006) 1.02
An epidermal microRNA regulates neuronal migration through control of the cellular glycosylation state. Science (2013) 1.02
Heparan sulfate chain valency controls syndecan-4 function in cell adhesion. J Biol Chem (2010) 1.02
Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways. Exp Cell Res (2007) 1.01
Heparan sulfate regulates fibrillin-1 N- and C-terminal interactions. J Biol Chem (2008) 1.01
Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan. J Invest Dermatol (2004) 1.00
Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin. Biochem J (2006) 1.00
Heparin-induced cis- and trans-dimerization modes of the thrombospondin-1 N-terminal domain. J Biol Chem (2007) 1.00
Syndecan-1 and syndecan-4 are independent indicators in breast carcinoma. J Histochem Cytochem (2011) 1.00
Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions. J Biol Chem (2011) 0.98
Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148. Mol Biol Cell (2011) 0.97
A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo. Hybridoma (Larchmt) (2007) 0.97
Syndecan-1 and -4 synthesized simultaneously by mouse mammary gland epithelial cells bear heparan sulfate chains that are apparently structurally indistinguishable. J Biol Chem (2003) 0.96
The binding properties of minimal oligosaccharides reveal a common heparan sulfate/dermatan sulfate-binding site in hepatocyte growth factor/scatter factor that can accommodate a wide variety of sulfation patterns. J Biol Chem (2008) 0.96
Syndecans-2 and -4; close cousins, but not identical twins. Mol Cells (2004) 0.96
Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate. J Biol Chem (2005) 0.95
Software tool for the structural determination of glycosaminoglycans by mass spectrometry. Anal Chem (2008) 0.95
Heparin octasaccharides inhibit angiogenesis in vivo. Clin Cancer Res (2005) 0.94
Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains. FEBS J (2013) 0.94
Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage. Exp Cell Res (2009) 0.93
Opticin binds to heparan and chondroitin sulfate proteoglycans. Invest Ophthalmol Vis Sci (2005) 0.92
Regulation of fibroblast growth factor-2 activity by human ovarian cancer tumor endothelium. Clin Cancer Res (2005) 0.92
The mode of action of heparan and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor. J Biol Chem (2001) 0.91
Specific structural features of heparan sulfate proteoglycans potentiate neuregulin-1 signaling. J Biol Chem (2004) 0.91
A developmentally regulated heparan sulfate epitope defines a subpopulation with increased blood potential during mesodermal differentiation. Stem Cells (2008) 0.91
Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes. Biophys J (2013) 0.90
Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry. Glycobiology (2007) 0.90
Characterization of the binding site on heparan sulfate for macrophage inflammatory protein 1alpha. Blood (2002) 0.90
Protein kinase C, focal adhesions and the regulation of cell migration. J Histochem Cytochem (2013) 0.89
Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans. J Histochem Cytochem (2012) 0.89
Localization of the transmembrane proteoglycan syndecan-4 and its regulatory kinases in costameres of rat cardiomyocytes: a deconvolution microscopic study. Anat Rec (2002) 0.89
Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides. J Biol Chem (2010) 0.88
Heparan sulfate regulates ADAM12 through a molecular switch mechanism. J Biol Chem (2008) 0.87
The newcomer in the integrin family: integrin α9 in biology and cancer. Adv Biol Regul (2012) 0.86
Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice. Cell Tissue Res (2009) 0.86
Structural and cell adhesion properties of zebrafish syndecan-4 are shared with higher vertebrates. J Biol Chem (2008) 0.86
Heparan sulfate 2-O-sulfotransferase (Hs2st) and mouse development. Glycoconj J (2003) 0.85
New insights into heparan sulphate biosynthesis from the study of mutant mice. Biochem Soc Symp (2002) 0.83
Hierarchy of ADAM12 binding to integrins in tumor cells. Exp Cell Res (2005) 0.82
Heparan sulfate biosynthesis: methods for investigation of the heparanosome. J Histochem Cytochem (2012) 0.82
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II. Mol Cell Biol (2012) 0.82
Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates. Biochem J (2003) 0.82
Detection of 2-O-sulfated iduronate and N-acetylglucosamine units in heparan sulfate by an antibody selected against acharan sulfate (IdoA2S-GlcNAc)n. J Biol Chem (2004) 0.81
Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism. Mol Biol Cell (2012) 0.81
Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis. J Histochem Cytochem (2004) 0.81
Heparin sequencing. Glycobiology (2002) 0.80
Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion. J Biol Chem (2013) 0.79
Molecular characterization of chicken syndecan-2 proteoglycan. Biochem J (2002) 0.79
Antimigratory and antimetastatic effect of heparin-derived 4-18 unit oligosaccharides in a preclinical human melanoma metastasis model. Thromb Haemost (2009) 0.76
The morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate. J Biol Chem (2006) 0.75
Celebrating 60 years. J Histochem Cytochem (2013) 0.75
Constants in an era of change. J Histochem Cytochem (2015) 0.75
Nondébridement of laser char after two carbon dioxide laser passes results in faster reepithelialization. Plast Reconstr Surg (2003) 0.75