Published in J Biol Chem on February 12, 2010
Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96
On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. J Biol Chem (2012) 1.04
Syndecan-4 signaling at a glance. J Cell Sci (2013) 1.01
Syndecans: from peripheral coreceptors to mainstream regulators of cell behaviour. Int J Exp Pathol (2014) 0.87
Characterization of heparanase-induced phosphatidylinositol 3-kinase-AKT activation and its integrin dependence. J Biol Chem (2013) 0.86
The glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans. Microsc Microanal (2012) 0.86
Syndecan-4 is a major syndecan in primary human endothelial cells in vitro, modulated by inflammatory stimuli and involved in wound healing. J Histochem Cytochem (2015) 0.85
Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci (2013) 0.84
Cytokines and growth factors cross-link heparan sulfate. Open Biol (2015) 0.84
The mutual impact of syndecan-1 and its glycosaminoglycan chains--a multivariable puzzle. J Histochem Cytochem (2012) 0.83
Specific sides to multifaceted glycosaminoglycans are observed in embryonic development. Semin Cell Dev Biol (2010) 0.82
Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels. J Cell Biol (2015) 0.79
Auxiliary and autonomous proteoglycan signaling networks. Methods Enzymol (2010) 0.78
Getting out of a sticky situation: targeting the myofibroblast in scleroderma. Open Rheumatol J (2012) 0.77
Syndecan-4 Regulates Muscle Differentiation and Is Internalized from the Plasma Membrane during Myogenesis. PLoS One (2015) 0.77
Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. Dis Model Mech (2016) 0.77
Transforming Growth Factor-β1 Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner. J Cell Biochem (2016) 0.75
ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Sci Rep (2016) 0.75
Redefining the role of syndecans in C. elegans biology. Worm (2016) 0.75
Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization. Open Biol (2017) 0.75
The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction. PLoS One (2016) 0.75
Recent Insights into Cell Surface Heparan Sulphate Proteoglycans and Cancer. F1000Res (2016) 0.75
Pathogenesis and Inhibition of Flaviviruses from a Carbohydrate Perspective. Pharmaceuticals (Basel) (2017) 0.75
Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74
Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature (2007) 7.87
Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry (1976) 6.00
Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J Cell Biol (2006) 3.37
Rapid methods for isolation of human plasma fibronectin. Thromb Res (1982) 3.35
Synergistic control of cell adhesion by integrins and syndecans. Nat Rev Mol Cell Biol (2007) 3.21
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4. J Clin Invest (2001) 2.78
Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA. Development (2008) 2.45
Syndecans: new kids on the signaling block. Circ Res (2005) 2.43
Syndecans: proteoglycan regulators of cell-surface microdomains? Nat Rev Mol Cell Biol (2003) 2.36
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. J Cell Biol (2007) 2.33
Control of morphology, cytoskeleton and migration by syndecan-4. J Cell Sci (1999) 2.17
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J Cell Biol (2003) 1.90
Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration. Genes Dev (2004) 1.89
Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J Exp Med (2009) 1.83
Syndecan-4 core protein is sufficient for the assembly of focal adhesions and actin stress fibers. J Cell Sci (1999) 1.76
Syndecan-4 modulates focal adhesion kinase phosphorylation. J Biol Chem (2002) 1.60
Syndecan-4 binding to the high affinity heparin-binding domain of fibronectin drives focal adhesion formation in fibroblasts. Arch Biochem Biophys (2000) 1.58
Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. Mol Biol Cell (2001) 1.56
Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions. J Biol Chem (2000) 1.55
PKCbeta-dependent activation of RhoA by syndecan-4 during focal adhesion formation. J Cell Sci (2006) 1.38
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. J Biol Chem (2003) 1.36
Heparan sulfate chains from glypican and syndecans bind the Hep II domain of fibronectin similarly despite minor structural differences. J Biol Chem (2000) 1.23
Transmembrane domain-induced oligomerization is crucial for the functions of syndecan-2 and syndecan-4. J Biol Chem (2005) 1.15
Characterization of ryudocan glycosaminoglycan acceptor sites. J Biol Chem (1994) 1.13
Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions. Proc Natl Acad Sci U S A (2007) 1.12
Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes. J Biol Chem (2005) 1.08
Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, the sting organelle, and structural characterization of glycosaminoglycans. Glycobiology (2007) 1.08
Cellular adhesion responses to the heparin-binding (HepII) domain of fibronectin require heparan sulfate with specific properties. J Biol Chem (2006) 1.06
Syndecan-4 regulates localization, activity and stability of protein kinase C-alpha. Biochem J (2004) 1.03
A conserved NXIP motif is required for cell adhesion properties of the syndecan-4 ectodomain. J Biol Chem (2006) 1.02
Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways. Exp Cell Res (2007) 1.01
Syndecan proteoglycan contributions to cytoskeletal organization and contractility. Scand J Med Sci Sports (2009) 0.95
Solution structure of the dimeric cytoplasmic domain of syndecan-4. Biochemistry (2001) 0.91
Structural and cell adhesion properties of zebrafish syndecan-4 are shared with higher vertebrates. J Biol Chem (2008) 0.86
RhoGDI: multiple functions in the regulation of Rho family GTPase activities. Biochem J (2005) 2.50
Tyrosinase expression in malignant melanoma, desmoplastic melanoma, and peripheral nerve tumors. Arch Pathol Lab Med (2002) 2.21
The Rho kinases I and II regulate different aspects of myosin II activity. J Cell Biol (2005) 2.16
Syndecans in wound healing, inflammation and vascular biology. Int J Biochem Cell Biol (2006) 2.05
Proteoglycans in health and disease: the multiple roles of syndecan shedding. FEBS J (2010) 1.58
Fibronectin matrix assembly requires distinct contributions from Rho kinases I and -II. Mol Biol Cell (2006) 1.54
Cellular roles of ADAM12 in health and disease. Int J Biochem Cell Biol (2008) 1.46
PKCbeta-dependent activation of RhoA by syndecan-4 during focal adhesion formation. J Cell Sci (2006) 1.38
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. J Biol Chem (2003) 1.36
Syndecans as receptors and organizers of the extracellular matrix. Cell Tissue Res (2009) 1.27
Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans. Matrix Biol (2003) 1.24
Syndecans as cell surface receptors: Unique structure equates with functional diversity. Matrix Biol (2010) 1.16
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. J Biol Chem (2002) 1.16
Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. J Mol Biol (2005) 1.14
Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J Biol Chem (2010) 1.13
The CMV early enhancer/chicken beta actin (CAG) promoter can be used to drive transgene expression during the differentiation of murine embryonic stem cells into vascular progenitors. BMC Cell Biol (2008) 1.12
Perlecan and tumor angiogenesis. J Histochem Cytochem (2003) 1.09
Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation. J Cell Sci (2007) 1.08
Syndecan-4 associates with alpha-actinin. J Biol Chem (2002) 1.07
Palmitoylation at Cys574 is essential for MT1-MMP to promote cell migration. FASEB J (2005) 1.07
Cellular adhesion responses to the heparin-binding (HepII) domain of fibronectin require heparan sulfate with specific properties. J Biol Chem (2006) 1.06
On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. J Biol Chem (2012) 1.04
A conserved NXIP motif is required for cell adhesion properties of the syndecan-4 ectodomain. J Biol Chem (2006) 1.02
An epidermal microRNA regulates neuronal migration through control of the cellular glycosylation state. Science (2013) 1.02
Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways. Exp Cell Res (2007) 1.01
Heparan sulfate regulates fibrillin-1 N- and C-terminal interactions. J Biol Chem (2008) 1.01
Regulation of ROCK activity in cancer. J Histochem Cytochem (2012) 1.01
Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan. J Invest Dermatol (2004) 1.00
Syndecan-1 and syndecan-4 are independent indicators in breast carcinoma. J Histochem Cytochem (2011) 1.00
Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions. J Biol Chem (2011) 0.98
Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148. Mol Biol Cell (2011) 0.97
A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo. Hybridoma (Larchmt) (2007) 0.97
Syndecans-2 and -4; close cousins, but not identical twins. Mol Cells (2004) 0.96
Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains. FEBS J (2013) 0.94
Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage. Exp Cell Res (2009) 0.93
Protein kinase C, focal adhesions and the regulation of cell migration. J Histochem Cytochem (2013) 0.89
Localization of the transmembrane proteoglycan syndecan-4 and its regulatory kinases in costameres of rat cardiomyocytes: a deconvolution microscopic study. Anat Rec (2002) 0.89
Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans. J Histochem Cytochem (2012) 0.89
Syndecans: from peripheral coreceptors to mainstream regulators of cell behaviour. Int J Exp Pathol (2014) 0.87
Heparan sulfate regulates ADAM12 through a molecular switch mechanism. J Biol Chem (2008) 0.87
The newcomer in the integrin family: integrin α9 in biology and cancer. Adv Biol Regul (2012) 0.86
Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice. Cell Tissue Res (2009) 0.86
Structural and cell adhesion properties of zebrafish syndecan-4 are shared with higher vertebrates. J Biol Chem (2008) 0.86
Hierarchy of ADAM12 binding to integrins in tumor cells. Exp Cell Res (2005) 0.82
Localization of Cladosporium fulvum hydrophobins reveals a role for HCf-6 in adhesion. FEMS Microbiol Lett (2008) 0.82
Heparan sulfate biosynthesis: methods for investigation of the heparanosome. J Histochem Cytochem (2012) 0.82
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II. Mol Cell Biol (2012) 0.82
Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis. J Histochem Cytochem (2004) 0.81
Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism. Mol Biol Cell (2012) 0.81
Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion. J Biol Chem (2013) 0.79
Novel insight into the biological functions of syndecan ectodomain core proteins. Biofactors (2013) 0.79
Toll-like receptors: Role in inflammation and therapeutic potential. Biofactors (2013) 0.79
Molecular characterization of chicken syndecan-2 proteoglycan. Biochem J (2002) 0.79
Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer. FASEB J (2013) 0.78
Production and secretion of Aspergillus nidulans catalase B in filamentous fungi driven by the promoter and signal peptide of the Cladosporium fulvum hydrophobin gene hcf-1. Curr Genet (2003) 0.77
Celebrating 60 years. J Histochem Cytochem (2013) 0.75
Nondébridement of laser char after two carbon dioxide laser passes results in faster reepithelialization. Plast Reconstr Surg (2003) 0.75
Constants in an era of change. J Histochem Cytochem (2015) 0.75
Quantitative evaluation by Tl-201 scintigraphy in the diagnosis of thyroid follicular nodules. Ann Nucl Med (2003) 0.75