Published in Mol Pharmacol on November 28, 2006
Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell. Hear Res (2011) 1.23
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Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways. Hear Res (2009) 1.15
Recent findings and emerging questions in cochlear noise injury. Hear Res (2008) 1.10
Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness. Hum Mol Genet (2009) 1.07
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Noise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damage. Hear Res (2010) 0.90
Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma. Int J Otolaryngol (2011) 0.84
Investors start backing hearing loss treatments. Nat Biotechnol (2013) 0.82
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Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hear Res (2010) 0.79
Reactive oxygen species, apoptosis, and mitochondrial dysfunction in hearing loss. Biomed Res Int (2015) 0.79
Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma. Front Cell Neurosci (2015) 0.78
JNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development. Front Cell Neurosci (2016) 0.75
Identification of a gene set to evaluate the potential effects of loud sounds from seismic surveys on the ears of fishes: a study with Salmo salar. J Fish Biol (2014) 0.75
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Protein transduction therapy into cochleae via the round window niche in guinea pigs. Mol Ther Methods Clin Dev (2016) 0.75
Pharmacological agents used for treatment and prevention in noise-induced hearing loss. Eur Arch Otorhinolaryngol (2016) 0.75
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med (2003) 3.45
Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists. Cell (2012) 3.22
Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice. Am J Hum Genet (2008) 1.65
Salicylate induces tinnitus through activation of cochlear NMDA receptors. J Neurosci (2003) 1.63
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. Diabetes (2004) 1.55
Physiology, pharmacology and plasticity at the inner hair cell synaptic complex. Hear Res (2006) 1.48
Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. Cancer Res (2004) 1.39
Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing. J Physiol (2004) 1.32
Salicylate enables cochlear arachidonic-acid-sensitive NMDA receptor responses. J Neurosci (2008) 1.24
OPA1 R445H mutation in optic atrophy associated with sensorineural deafness. Ann Neurol (2005) 1.18
D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia. Stroke (2004) 1.16
Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity. Hear Res (2006) 1.14
Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons. Eur J Neurosci (2004) 1.12
Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. FASEB J (2008) 1.10
Deafness and cochlear fibrocyte alterations in mice deficient for the inner ear protein otospiralin. Mol Cell Biol (2005) 1.09
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo. Am J Physiol Heart Circ Physiol (2006) 1.08
JNK inhibition and inflammation after cerebral ischemia. Brain Behav Immun (2009) 1.08
Induction of apoptosis in human corneal and HeLa cells by mutated BIGH3. Invest Ophthalmol Vis Sci (2003) 1.08
Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea. Antioxid Redox Signal (2011) 1.05
The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse. Brain (2012) 1.03
Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol (2007) 1.01
The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci (2013) 1.01
Characteristics of tinnitus and etiology of associated hearing loss: a study of 123 patients. Int Tinnitus J (2002) 1.00
Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta (2007) 1.00
FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear. J Biol Chem (2007) 0.98
Degeneration of sensory outer hair cells following pharmacological blockade of cochlear KCNQ channels in the adult guinea pig. Eur J Neurosci (2003) 0.96
A unique set of SH3-SH3 interactions controls IB1 homodimerization. EMBO J (2006) 0.95
Tmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing. J Biol Chem (2011) 0.94
Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition. J Neurochem (2010) 0.93
Ryanodine receptors and BK channels act as a presynaptic depressor of neurotransmission in cochlear inner hair cells. Eur J Neurosci (2005) 0.92
A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells. Oncogene (2004) 0.92
Characteristics of tinnitus in a population of 555 patients: specificities of tinnitus induced by noise trauma. Int Tinnitus J (2006) 0.91
Use of cell-permeable peptides to prevent neuronal degeneration. Trends Mol Med (2004) 0.91
c-Jun N-terminal kinase pathway inhibition in intracerebral hemorrhage. Cerebrovasc Dis (2010) 0.90
Downregulation of otospiralin, a novel inner ear protein, causes hair cell degeneration and deafness. J Neurosci (2002) 0.90
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator. Cerebrovasc Dis (2008) 0.89
D-TAT transporter as an ocular peptide delivery system. Clin Experiment Ophthalmol (2005) 0.88
m-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in rats. Eur J Neurosci (2005) 0.88
Control of hair cell excitability by vestibular primary sensory neurons. J Neurosci (2007) 0.88
c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus. Eur J Neurosci (2010) 0.88
Macrophage contribution to the response of the rat organ of Corti to amikacin. J Neurosci Res (2007) 0.88
Efficient and specific transduction of cochlear supporting cells by adeno-associated virus serotype 5. Neurosci Lett (2008) 0.87
The JNK inhibitor D-JNKI-1 blocks apoptotic JNK signaling in brain mitochondria. Mol Cell Neurosci (2011) 0.85
Spatiotemporal pattern of action potential firing in developing inner hair cells of the mouse cochlea. Proc Natl Acad Sci U S A (2014) 0.85
A novel dual inhibitor of calpains and lipid peroxidation (BN82270) rescues the cochlea from sound trauma. Neuropharmacology (2007) 0.84
Identification of factors that maintain mammalian outer hair cells in adult organ of Corti explants. Hear Res (2002) 0.84
JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling. PLoS One (2012) 0.84
The inner hair cell synaptic complex: physiology, pharmacology and new therapeutic strategies. Audiol Neurootol (2002) 0.84
Role of JNK isoforms in the development of neuropathic pain following sciatic nerve transection in the mouse. Mol Pain (2012) 0.83
Medial olivocochlear efferent activity in awake guinea pigs. Neuroreport (2004) 0.83
Tmprss3 loss of function impairs cochlear inner hair cell Kcnma1 channel membrane expression. Hum Mol Genet (2012) 0.83
Brief reoxygenation episodes during chronic hypoxia enhance posthypoxic recovery of LV function: role of mitogen-activated protein kinase signaling pathways. Basic Res Cardiol (2006) 0.83
D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma. Otol Neurotol (2006) 0.82
Supporting cells regulate the remodelling of aminoglycoside-injured organ of Corti, through the release of high mobility group box 1. Eur J Neurosci (2013) 0.82
Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1. J Biol Chem (2003) 0.82
A procedure to label inner ear afferent nerve endings for calcium imaging. Brain Res Brain Res Protoc (2004) 0.82
Transduction and encoding sensory information by skin mechanoreceptors. Pflugers Arch (2014) 0.82
Contralateral sound stimulation suppresses the compound action potential from the auditory nerve in humans. Otol Neurotol (2002) 0.81
Homogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates. J Biomol Screen (2006) 0.81
Hypergravity affects the developmental expression of voltage-gated sodium current in utricular hair cells. Neuroreport (2006) 0.81
Cochlear efferents in developing adult and pathological conditions. Cell Tissue Res (2015) 0.80
Dynamic expression of FXYD6 in the inner ear suggests a role of the protein in endolymph homeostasis and neuronal activity. Dev Dyn (2007) 0.80
The risks of amplified music for disc-jockeys working in nightclubs. Ear Hear (2009) 0.80
Dopamine transporter is essential for the maintenance of spontaneous activity of auditory nerve neurones and their responsiveness to sound stimulation. J Neurochem (2006) 0.79
Molecular and cellular mechanisms of loss of residual hearing after cochlear implantation. Ann Otol Rhinol Laryngol (2013) 0.79
Early maturation of evoked otoacoustic emissions and medial olivocochlear reflex in preterm neonates. Pediatr Res (2006) 0.79
Antitumorigenic effect of proteasome inhibitors on insulinoma cells. Endocrinology (2004) 0.79
Pure-tone threshold description of an elderly French screened population. Otol Neurotol (2008) 0.79
Piezo-electrically driven mechanical stimulation of sensory neurons. Methods Mol Biol (2013) 0.78
New pharmacological strategies to restore hearing and treat tinnitus. Acta Otolaryngol (2004) 0.78
Profiling treatment-specific post-translational modifications in a complex proteome with subtractive substrate phage display. Proteomics (2004) 0.78
Large Family With Maturity-Onset Diabetes of the Young and a Novel V121I Mutation in HNF4A. Hum Mutat (2002) 0.77
Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein. Acta Crystallogr D Biol Crystallogr (2003) 0.77
Ultrastructure of the Odontocete organ of Corti: scanning and transmission electron microscopy. J Comp Neurol (2014) 0.77
From cochlear cell death pathways to new pharmacological therapies. Mini Rev Med Chem (2008) 0.75
[The diversity of aging models]. Med Sci (Paris) (2012) 0.75
Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels. Mol Cell Biochem (2008) 0.75
Induction of localized cochlear hypothermia. Acta Otolaryngol (2007) 0.75
[A new hope: restoration of auditory evoked responses]. Med Sci (Paris) (2013) 0.75
Microtubule-associated protein 2 (MAP2) expression during synaptic plasticity in the guinea pig cochlea. Hear Res (2003) 0.75