Published in J Biol Chem on November 29, 2006
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature (2009) 5.55
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Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid Redox Signal (2009) 1.71
NADPH oxidases in lung biology and pathology: host defense enzymes, and more. Free Radic Biol Med (2007) 1.50
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Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB J (2008) 1.36
Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity. Sci Signal (2009) 1.29
NOX enzymes and pulmonary disease. Antioxid Redox Signal (2009) 1.29
Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila. PLoS Genet (2011) 1.26
Caenorhabditis elegans and human dual oxidase 1 (DUOX1) "peroxidase" domains: insights into heme binding and catalytic activity. J Biol Chem (2009) 1.25
The role of transcription-independent damage signals in the initiation of epithelial wound healing. Nat Rev Mol Cell Biol (2013) 1.23
ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli. J Biol Chem (2009) 1.21
Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli. Free Radic Biol Med (2009) 1.17
Localized elasticity measured in epithelial cells migrating at a wound edge using atomic force microscopy. Am J Physiol Lung Cell Mol Physiol (2008) 1.12
Arsenic upregulates MMP-9 and inhibits wound repair in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 1.12
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. J Cell Sci (2009) 1.11
Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha. J Biol Chem (2008) 1.08
Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding. Mol Biol Cell (2009) 1.03
Wounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short- and long-range mechanisms. Mol Biol Cell (2008) 1.03
NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone. Am J Physiol Heart Circ Physiol (2012) 0.99
NADPH oxidases: a perspective on reactive oxygen species production in tumor biology. Antioxid Redox Signal (2013) 0.99
Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair. J Biol Chem (2010) 0.98
ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17. PLoS One (2013) 0.98
Mechanisms of epithelial wound detection. Trends Cell Biol (2015) 0.96
Redox warfare between airway epithelial cells and Pseudomonas: dual oxidase versus pyocyanin. Immunol Res (2009) 0.96
Characterization of hydrogen peroxide production by Duox in bronchial epithelial cells exposed to Pseudomonas aeruginosa. FEBS Lett (2010) 0.95
Hydrogen peroxide as a damage signal in tissue injury and inflammation: murderer, mediator, or messenger? J Cell Biochem (2014) 0.92
Nox enzymes in allergic airway inflammation. Biochim Biophys Acta (2011) 0.91
Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury. Am J Respir Cell Mol Biol (2012) 0.91
Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling. Free Radic Biol Med (2011) 0.90
Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses. J Allergy Clin Immunol (2015) 0.90
Dual oxidase regulates neutrophil recruitment in allergic airways. Free Radic Biol Med (2013) 0.89
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. FASEB J (2012) 0.87
Normoxic cyclic GMP-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing. Nitric Oxide (2012) 0.86
The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells. PLoS One (2011) 0.86
Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions. Free Radic Biol Med (2011) 0.86
Stanniocalcin-1 regulates extracellular ATP-induced calcium waves in human epithelial cancer cells by stimulating ATP release from bystander cells. PLoS One (2010) 0.85
Histamine stimulates hydrogen peroxide production by bronchial epithelial cells via histamine H1 receptor and dual oxidase. Am J Respir Cell Mol Biol (2014) 0.85
Arsenic alters ATP-dependent Ca²+ signaling in human airway epithelial cell wound response. Toxicol Sci (2011) 0.85
Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration. Purinergic Signal (2011) 0.84
Poloxamer 188 facilitates the repair of alveolus resident cells in ventilator-injured lungs. Am J Respir Crit Care Med (2011) 0.84
All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium. Am J Physiol Lung Cell Mol Physiol (2010) 0.84
PARADOXICAL ROLES OF DUAL OXIDASES IN CANCER BIOLOGY. Free Radic Biol Med (2017) 0.83
Development of the first oligonucleotide microarray for global gene expression profiling in guinea pigs: defining the transcription signature of infectious diseases. BMC Genomics (2012) 0.82
Chronic arsenic exposure in nanomolar concentrations compromises wound response and intercellular signaling in airway epithelial cells. Toxicol Sci (2012) 0.81
Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells. Redox Biol (2014) 0.80
NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/alpha3 integrins. Mol Cell Biol (2009) 0.80
The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling. J Biol Chem (2016) 0.77
Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway. BMC Microbiol (2016) 0.76
DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways. PLoS One (2015) 0.75
Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression. Sci Rep (2017) 0.75
DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties. Oncogenesis (2016) 0.75
Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7. J Immunol (2015) 0.75
IKKα regulates human keratinocyte migration through surveillance of the redox environment. J Cell Sci (2017) 0.75
Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia. Am J Respir Cell Mol Biol (2012) 0.75
Decoding NADPH oxidase 4 expression in human tumors. Redox Biol (2017) 0.75
Wound induced Ca(2+) wave propagates through a simple Release and Diffusion mechanism. Mol Biol Cell (2017) 0.75
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A (2006) 2.51
Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation. Proc Natl Acad Sci U S A (2004) 2.19
Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. J Cell Biol (2006) 1.84
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2013) 1.73
Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway. Antioxid Redox Signal (2006) 1.67
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol (2012) 1.32
Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proc Am Thorac Soc (2009) 1.31
Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. J Clin Invest (2013) 1.31
In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization. Biochim Biophys Acta (2006) 1.27
Nitric oxide promotes airway epithelial wound repair through enhanced activation of MMP-9. Am J Respir Cell Mol Biol (2006) 1.27
ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli. J Biol Chem (2009) 1.21
Characterisation of the cutaneous pathology in non-small cell lung cancer (NSCLC) patients treated with the EGFR tyrosine kinase inhibitor erlotinib. Eur J Cancer (2010) 1.21
Multiple contributing roles for NOS2 in LPS-induced acute airway inflammation in mice. Am J Physiol Lung Cell Mol Physiol (2003) 1.17
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. J Immunol (2008) 1.13
Susceptibility to ozone-induced acute lung injury in iNOS-deficient mice. Am J Physiol Lung Cell Mol Physiol (2002) 1.09
Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha. J Biol Chem (2008) 1.08
Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein. Antioxid Redox Signal (2005) 1.06
Regulation of constitutive neutrophil apoptosis by the alpha,beta-unsaturated aldehydes acrolein and 4-hydroxynonenal. Am J Physiol Lung Cell Mol Physiol (2005) 1.05
Nitric oxide and reactive nitrogen species in airway epithelial signaling and inflammation. Free Radic Biol Med (2006) 1.05
Venous valvular stasis-associated hypoxia and thrombosis: what is the link? Annu Rev Physiol (2011) 1.03
Ozone exposure activates oxidative stress responses in murine skin. Toxicology (2002) 1.02
Proteomic profiling of acrolein adducts in human lung epithelial cells. J Proteomics (2011) 1.00
Oxidative-nitrosative stress and post-translational protein modifications: implications to lung structure-function relations. Arginase modulates NF-kappaB activity via a nitric oxide-dependent mechanism. Am J Respir Cell Mol Biol (2007) 1.00
Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice. Cancer Res (2005) 1.00
In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation. Nitric Oxide (2004) 0.99
Interactions between nitric oxide and hypoxia-inducible factor signaling pathways in inflammatory disease. Nitric Oxide (2011) 0.99
ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17. PLoS One (2013) 0.98
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol (2012) 0.97
Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor. Biomaterials (2013) 0.95
The tobacco smoke component, acrolein, suppresses innate macrophage responses by direct alkylation of c-Jun N-terminal kinase. Am J Respir Cell Mol Biol (2012) 0.94
Surrogate genetics and metabolic profiling for characterization of human disease alleles. Genetics (2012) 0.94
Acrolein inhalation suppresses lipopolysaccharide-induced inflammatory cytokine production but does not affect acute airways neutrophilia. J Immunol (2008) 0.94
Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction. Am J Physiol Lung Cell Mol Physiol (2011) 0.92
Airway epithelial indoleamine 2,3-dioxygenase inhibits CD4+ T cells during Aspergillus fumigatus antigen exposure. Am J Respir Cell Mol Biol (2010) 0.92
Strain-dependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol (2009) 0.92
Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury. Am J Respir Cell Mol Biol (2012) 0.91
Induction of stress proteins and MMP-9 by 0.8 ppm of ozone in murine skin. Biochem Biophys Res Commun (2003) 0.91
Nitric oxide and redox signaling in allergic airway inflammation. Antioxid Redox Signal (2005) 0.91
Identification of glutathione modifications by cigarette smoke. Free Radic Biol Med (2002) 0.90
Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling. Free Radic Biol Med (2011) 0.90
Venom proteomic characterization and relative antivenom neutralization of two medically important Pakistani elapid snakes (Bungarus sindanus and Naja naja). J Proteomics (2013) 0.90
Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells. Part Fibre Toxicol (2010) 0.90
Nitric oxide-evoked transient kinetics of cyclic GMP in vascular smooth muscle cells. Cell Signal (2006) 0.87
Nitric oxide and airway epithelial barrier function: regulation of tight junction proteins and epithelial permeability. Arch Biochem Biophys (2008) 0.86
Nitric oxide regulation of MMP-9 activation and its relationship to modifications of the cysteine switch. Biochemistry (2008) 0.86
Inhibition of TNFalpha-induced cyclooxygenase-2 expression by amentoflavone through suppression of NF-kappaB activation in A549 cells. Mol Cell Biochem (2002) 0.85
Modulation of NF-κB and hypoxia-inducible factor--1 by S-nitrosoglutathione does not alter allergic airway inflammation in mice. Am J Respir Cell Mol Biol (2010) 0.85
Lycopene inhibits the growth of normal human prostate epithelial cells in vitro. J Nutr (2003) 0.85
Protein alkylation by the α,β-unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling? FEBS Lett (2013) 0.85
Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1. Redox Biol (2013) 0.84
S-nitrosothiols inhibit cytokine-mediated induction of matrix metalloproteinase-9 in airway epithelial cells. Am J Respir Cell Mol Biol (2002) 0.84
GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein. FEBS Lett (2007) 0.83
Acrolein exposure suppresses antigen-induced pulmonary inflammation. Respir Res (2013) 0.83
Emerging mechanisms of glutathione-dependent chemistry in biology and disease. J Cell Biochem (2013) 0.83
Purinergic signaling in wound healing and airway remodeling. Subcell Biochem (2011) 0.80
Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment. J Neurovirol (2014) 0.79
Environmental oxidant pollutant effects on biologic systems: a focus on micronutrient antioxidant-oxidant interactions. Am J Respir Crit Care Med (2002) 0.79
Quantitation and localization of tyrosine nitration in proteins. Methods Enzymol (2002) 0.77
Reactive nitrogen species in refractory asthma: markers or players? J Allergy Clin Immunol (2008) 0.76
SOD inactivation in asthma: bad or no news? Am J Pathol (2005) 0.76
Oxidants are not all created equal: could hydrogen peroxide actually be good for our lungs? Am J Respir Crit Care Med (2009) 0.75
Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts. BMC Cancer (2013) 0.75
Can selenoenzymes resist electrophilic modification? Evidence from thioredoxin reductase and a mutant containing alpha-methylselenocysteine. Biochemistry (2020) 0.75
Frontiers in nitric oxide and redox signaling. Nitric Oxide (2011) 0.75