PubRank

Heikki Tanila

Author PubWeight™ 86.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci 2009 2.33
2 Neurocognitive aging: prior memories hinder new hippocampal encoding. Trends Neurosci 2006 2.20
3 Age-associated alterations of hippocampal place cells are subregion specific. J Neurosci 2005 1.82
4 Increased fMRI responses during encoding in mild cognitive impairment. Neurobiol Aging 2006 1.74
5 Role of alpha-synuclein in presynaptic dopamine recruitment. J Neurosci 2004 1.74
6 Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans. Eur J Neurosci 2004 1.63
7 Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease. J Neurochem 2013 1.51
8 Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice. Neurobiol Dis 2003 1.48
9 Orexin loss in Huntington's disease. Hum Mol Genet 2004 1.33
10 Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 2009 1.31
11 Flexible polyimide microelectrode array for in vivo recordings and current source density analysis. Biosens Bioelectron 2006 1.28
12 Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden. J Neurosci 2007 1.28
13 Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease. J Neuroinflammation 2010 1.18
14 Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. J Pharmacol Exp Ther 2004 1.17
15 Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice. Neurobiol Dis 2004 1.17
16 Cognitive aging and the hippocampus: how old rats represent new environments. J Neurosci 2004 1.17
17 Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors. Eur J Neurosci 2006 1.15
18 Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. Neurobiol Aging 2007 1.15
19 Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein. Neurobiol Dis 2005 1.15
20 Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man. Psychopharmacology (Berl) 2005 1.14
21 Nuclear factor erythroid 2-related factor 2 protects against beta amyloid. Mol Cell Neurosci 2008 1.11
22 Encoding of novel picture pairs activates the perirhinal cortex: an fMRI study. Hippocampus 2003 1.10
23 Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain 2011 1.10
24 Hypothermia in mice tested in Morris water maze. Behav Brain Res 2003 1.09
25 Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice. J Neurosci Res 2010 1.08
26 WNT signaling in activated microglia is proinflammatory. Glia 2010 1.07
27 Cognition-enhancing and anxiolytic effects of memantine. Neuropharmacology 2008 1.06
28 Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. Neurobiol Dis 2008 1.03
29 Role of alpha-synuclein in synaptic glutamate release. Neurobiol Dis 2007 1.02
30 Individual differences in neurocognitive aging of the medial temporal lobe. Age (Dordr) 2006 1.01
31 Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice. Neurobiol Aging 2011 1.01
32 Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer's disease. J Neuroinflammation 2012 0.99
33 Effects of ovariectomy and estrogen treatment on learning and hippocampal neurotransmitters in mice. Horm Behav 2002 0.97
34 Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice. Neurobiol Dis 2002 0.97
35 Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes. Glia 2011 0.96
36 Cholinergic system regulation of spatial representation by the hippocampus. Hippocampus 2002 0.95
37 Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels. Epilepsy Res 2011 0.95
38 Decreased reuptake of dopamine in the dorsal striatum in the absence of α-synuclein. Brain Res 2011 0.95
39 Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment. Hippocampus 2009 0.94
40 Estrogen treatment alleviates NMDA-antagonist induced hippocampal LTP blockade and cognitive deficits in ovariectomized mice. Neurobiol Learn Mem 2003 0.92
41 Effects of long-term ovariectomy and estrogen treatment on maze learning in aged mice. Exp Gerontol 2004 0.92
42 Mobile phone radiation and the developing brain: behavioral and morphological effects in juvenile rats. Radiat Res 2007 0.92
43 Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. J Neurosci 2010 0.91
44 Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease. Acta Neuropathol 2012 0.90
45 Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice. Brain Res 2007 0.90
46 Noradrenaline overflow in mouse dentate gyrus following locus coeruleus and natural stimulation: real-time monitoring by in vivo voltammetry. J Neurochem 2005 0.89
47 Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice. J Neurochem 2006 0.88
48 Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology. Neurosci Lett 2008 0.88
49 Distinct and overlapping fMRI activation networks for processing of novel identities and locations of objects. Eur J Neurosci 2005 0.87
50 Neurotrophins and dementia--keeping in touch. Neuron 2006 0.87
51 Fabrication and testing of polyimide-based microelectrode arrays for cortical mapping of evoked potentials. Biosens Bioelectron 2009 0.87
52 Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice. Neurobiol Dis 2010 0.87
53 From brain to food: analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin-plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry. J Chromatogr A 2011 0.87
54 Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus. J Neural Transm (Vienna) 2008 0.86
55 Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment. Pharmacol Biochem Behav 2004 0.86
56 Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice. J Cell Mol Med 2012 0.86
57 Brain reward in the absence of alpha-synuclein. Neuroreport 2006 0.85
58 Effects of NMDA-receptor antagonist treatment on c-fos expression in rat brain areas implicated in schizophrenia. Cell Mol Neurobiol 2004 0.85
59 Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β(1-42). Neuropharmacology 2012 0.85
60 Methylphenidate modifies overflow and presynaptic compartmentalization of dopamine via an α-synuclein-dependent mechanism. J Pharmacol Exp Ther 2012 0.85
61 Alteration of cortical EEG in mice carrying mutated human APP transgene. Brain Res 2002 0.85
62 Place cells of aged rats in two visually identical compartments. Neurobiol Aging 2004 0.84
63 The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease. PLoS One 2013 0.84
64 Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease. J Nutr Biochem 2012 0.83
65 In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse nucleus accumbens. J Neurochem 2004 0.83
66 Behavioural and neurochemical response of alpha-synuclein A30P transgenic mice to the effects of L-DOPA. Neuropharmacology 2008 0.83
67 A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis. J Neurosci Methods 2010 0.83
68 Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP+PS1 mice. Behav Brain Res 2002 0.82
69 In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse prefrontal cortex. Eur J Neurosci 2002 0.82
70 Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation. Proc Natl Acad Sci U S A 2012 0.81
71 Artificial theta stimulation impairs encoding of contextual fear memory. PLoS One 2012 0.81
72 Increased cortical and thalamic excitability in freely moving APPswe/PS1dE9 mice modeling epileptic activity associated with Alzheimer's disease. Cereb Cortex 2012 0.81
73 Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study. J Neurosci 2013 0.81
74 Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice. Neuroreport 2003 0.80
75 Fimbria-fornix lesion does not affect APP levels and amyloid deposition in the hippocampus of APP+PS1 double transgenic mice. Exp Neurol 2002 0.80
76 Genetic ablation of tenascin-C expression leads to abnormal hippocampal CA1 structure and electrical activity in vivo. Hippocampus 2009 0.80
77 Alpha 2C-adrenoceptor mediated regulation of cortical EEG arousal. Neuropharmacology 2002 0.79
78 Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction. FEBS Lett 2007 0.79
79 Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2. FASEB J 2013 0.79
80 Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats. Neuropharmacology 2011 0.79
81 Pharmacological characterisation of a structurally novel α2C-adrenoceptor antagonist ORM-10921 and its effects in neuropsychiatric models. Basic Clin Pharmacol Toxicol 2013 0.78
82 Increased hippocampal and cortical beta oscillations in mice deficient for the HNK-1 sulfotransferase. Mol Cell Neurosci 2006 0.77
83 Elevated levels of Abeta1-40 and Abeta1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice. Neurosci Lett 2002 0.77
84 Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe/PS1dE9 Mice. Curr Alzheimer Res 2015 0.77
85 Mechanics of self-stimulation and dopamine release in the nucleus accumbens. Neuroreport 2007 0.77
86 PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease. Cell Physiol Biochem 2014 0.76
87 Development of flexible microelectrode arrays for recording cortical surface field potentials. Conf Proc IEEE Eng Med Biol Soc 2008 0.75
88 Is it possible to improve memory with drugs in health people? Duodecim 1 0.75
89 [Not Available]. Duodecim 2006 0.75
90 [Curative treatment of Alzheimer's disease is still missing--is amyloid plaque hypothesis the wrong starting point?]. Duodecim 2015 0.75
91 Intravenous immunoglobulins for Alzheimer's disease. Curr Alzheimer Res 2014 0.75
92 Normal Amplitude of Electroretinography and Visual Evoked Potential Responses in AβPP/PS1 Mice. J Alzheimers Dis 2016 0.75