Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis.

PubWeight™: 1.87‹?› | Rank: Top 3%

🔗 View Article (PMC 1829118)

Published in J Clin Microbiol on December 13, 2006

Authors

Renate J van den Berg1, Inge Schaap, Kate E Templeton, Corné H W Klaassen, Ed J Kuijper

Author Affiliations

1: Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.

Articles citing this

The changing epidemiology of Clostridium difficile infections. Clin Microbiol Rev (2010) 4.48

Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. J Clin Microbiol (2007) 3.60

Characterization of Clostridium difficile isolates using capillary gel electrophoresis-based PCR ribotyping. J Med Microbiol (2008) 2.17

Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories. Clin Microbiol Rev (2013) 1.85

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. PLoS One (2012) 1.40

Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains. J Clin Microbiol (2008) 1.30

Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance. J Clin Microbiol (2010) 1.23

Coexistence of multiple multilocus variable-number tandem-repeat analysis subtypes of Clostridium difficile PCR ribotype 027 strains within fecal specimens. J Clin Microbiol (2010) 1.23

Multilocus variable-number tandem-repeat analysis and multilocus sequence typing reveal genetic relationships among Clostridium difficile isolates genotyped by restriction endonuclease analysis. J Clin Microbiol (2009) 1.21

Clostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes (2010) 1.19

Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. J Med Microbiol (2011) 1.16

Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. Antimicrob Agents Chemother (2014) 1.08

Typing Clostridium difficile strains based on tandem repeat sequences. BMC Microbiol (2009) 1.06

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. BMC Genomics (2015) 1.03

Comparison of multilocus variable-number tandem-repeat analysis and whole-genome sequencing for investigation of Clostridium difficile transmission. J Clin Microbiol (2013) 1.01

An enhanced DNA fingerprinting service to investigate potential Clostridium difficile infection case clusters sharing the same PCR ribotype. J Clin Microbiol (2011) 1.00

Utilizing rapid multiple-locus variable-number tandem-repeat analysis typing to aid control of hospital-acquired Clostridium difficile Infection: a multicenter study. J Clin Microbiol (2012) 0.96

Molecular analysis of Clostridium difficile at a university teaching hospital in Japan: a shift in the predominant type over a five-year period. Eur J Clin Microbiol Infect Dis (2007) 0.95

Extended multilocus variable-number tandem-repeat analysis of Clostridium difficile correlates exactly with ribotyping and enables identification of hospital transmission. J Clin Microbiol (2011) 0.90

Development and evaluation of a novel, semiautomated Clostridium difficile typing platform. J Clin Microbiol (2012) 0.90

Modified multiple-locus variable-number tandem-repeat analysis for rapid identification and typing of Clostridium difficile during institutional outbreaks. J Clin Microbiol (2011) 0.90

Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins. Appl Environ Microbiol (2014) 0.89

Clostridium difficile genotypes in piglet populations in Germany. J Clin Microbiol (2013) 0.88

Clindamycin-resistant clone of Clostridium difficile PCR Ribotype 027, Europe. Emerg Infect Dis (2008) 0.85

Comparison of PCR ribotyping and multilocus variable-number tandem-repeat analysis (MLVA) for improved detection of Clostridium difficile. BMC Microbiol (2011) 0.85

Comparative transcriptional analysis of clinically relevant heat stress response in Clostridium difficile strain 630. PLoS One (2012) 0.85

Molecular genetic basis of ribotyping. Clin Microbiol Rev (2008) 0.82

Molecular epidemiology of Clostridium difficile at a medical center in Taiwan: persistence of genetically clustering of A⁻B⁺ isolates and increase of A⁺B⁺ isolates. PLoS One (2013) 0.82

Antimicrobial resistance, toxinotype, and genotypic profiling of Clostridium difficile isolates of swine origin. J Clin Microbiol (2012) 0.81

Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164. BMC Microbiol (2012) 0.81

The First Two Clostridium difficile Ribotype 027/ST1 Isolates Identified in Beijing, China-an Emerging Problem or a Neglected Threat? Sci Rep (2016) 0.80

Molecular Epidemiology and Antimicrobial Susceptibility of Clostridium difficile Isolates from a University Teaching Hospital in China. Front Microbiol (2016) 0.77

Characterisation of Clostridium difficile strains isolated from Groote Schuur Hospital, Cape Town, South Africa. Eur J Clin Microbiol Infect Dis (2016) 0.76

DNA microarray-based PCR ribotyping of Clostridium difficile. J Clin Microbiol (2014) 0.75

Management of a cluster of Clostridium difficile infections among patients with osteoarticular infections. Antimicrob Resist Infect Control (2017) 0.75

Clostridium difficile Ribotype 023 Lacks the Ability To Hydrolyze Esculin, Leading to False-Negative Results on Chromogenic Agar. J Clin Microbiol (2016) 0.75

Clinical features and characteristics of Clostridium difficile PCR-ribotype 176 infection: results from a 1-year university hospital internal ward study. Ann Clin Microbiol Antimicrob (2015) 0.75

Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. Eur J Clin Microbiol Infect Dis (2016) 0.75

The emergence of Clostridium difficile PCR-ribotype 001 in Slovakia. Eur J Clin Microbiol Infect Dis (2015) 0.75

In recurrent C. difficile, the CRP response to the primary C. difficile infection predicts whether the same strain or a different strain will cause a second infection. Dig Dis Sci (2013) 0.75

Articles cited by this

A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med (2005) 16.59

Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. CMAJ (2004) 9.93

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02

Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect (2006) 6.90

PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol (1999) 5.58

A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol (1998) 4.79

Development of a new PCR-ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing. FEMS Microbiol Lett (1999) 4.27

Multiple-locus variable number tandem repeats analysis for genetic fingerprinting of pathogenic bacteria. Electrophoresis (2005) 3.29

Multilocus variable-number tandem-repeat analysis for investigation of Clostridium difficile transmission in Hospitals. J Clin Microbiol (2006) 2.52

Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea. J Clin Microbiol (2000) 2.50

Use of a novel panel of nine short tandem repeats for exact and high-resolution fingerprinting of Aspergillus fumigatus isolates. J Clin Microbiol (2005) 2.36

An outbreak of toxin A negative, toxin B positive Clostridium difficile-associated diarrhea in a Canadian tertiary-care hospital. Can Commun Dis Rep (1999) 2.04

Characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates from outbreaks in different countries by amplified fragment length polymorphism and PCR ribotyping. J Clin Microbiol (2004) 1.73

Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain. Eur J Clin Microbiol Infect Dis (2001) 1.71

Clostridium difficile ribotype 027, toxinotype III, the Netherlands. Emerg Infect Dis (2006) 1.52

Prevalence and association of PCR ribotypes of Clostridium difficile isolated from symptomatic patients from Warsaw with macrolide-lincosamide-streptogramin B (MLSB) type resistance. J Med Microbiol (2006) 1.39

Molecular epidemiology of endemic Clostridium difficile infection and the significance of subtypes of the United Kingdom epidemic strain (PCR ribotype 1). J Clin Microbiol (2005) 1.15

Articles by these authors

Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med (2013) 20.65

Peritoneal dialysis-related infections recommendations: 2010 update. Perit Dial Int (2010) 12.06

Clostridium difficile infection in Europe: a hospital-based survey. Lancet (2011) 6.25

High-throughput identification of bacteria and yeast by matrix-assisted laser desorption ionization-time of flight mass spectrometry in conventional medical microbiology laboratories. J Clin Microbiol (2010) 5.71

Peritoneal dialysis-related infections recommendations: 2005 update. Perit Dial Int (2005) 5.49

Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study. Lancet Infect Dis (2011) 3.93

Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078. Clin Infect Dis (2008) 3.49

Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009. Emerg Infect Dis (2011) 2.84

Surgical excision versus antibiotic treatment for nontuberculous mycobacterial cervicofacial lymphadenitis in children: a multicenter, randomized, controlled trial. Clin Infect Dis (2007) 2.73

A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic. Genome Res (2013) 2.59

Presence of a novel DNA methylation enzyme in methicillin-resistant Staphylococcus aureus isolates associated with pig farming leads to uninterpretable results in standard pulsed-field gel electrophoresis analysis. J Clin Microbiol (2006) 2.43

Use of a novel panel of nine short tandem repeats for exact and high-resolution fingerprinting of Aspergillus fumigatus isolates. J Clin Microbiol (2005) 2.36

Evaluation of real-time PCR and conventional diagnostic methods for the detection of Clostridium difficile-associated diarrhoea in a prospective multicentre study. J Med Microbiol (2007) 2.18

Comparison of the Luminex Respiratory Virus Panel fast assay with in-house real-time PCR for respiratory viral infection diagnosis. J Clin Microbiol (2010) 2.11

Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles. Clin Infect Dis (2013) 2.09

An outbreak of Pneumocystis jiroveci pneumonia with 1 predominant genotype among renal transplant recipients: interhuman transmission or a common environmental source? Clin Infect Dis (2007) 1.94

Azole-resistant central nervous system aspergillosis. Clin Infect Dis (2009) 1.94

Emergence of reduced susceptibility to metronidazole in Clostridium difficile. J Antimicrob Chemother (2008) 1.91

Molecular tracing of the emergence, adaptation, and transmission of hospital-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A (2012) 1.83

Prospective multicenter evaluation of a new immunoassay and real-time PCR for rapid diagnosis of Clostridium difficile-associated diarrhea in hospitalized patients. J Clin Microbiol (2005) 1.80

Coexistence of multiple PCR-ribotype strains of Clostridium difficile in faecal samples limits epidemiological studies. J Med Microbiol (2005) 1.78

Characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates from outbreaks in different countries by amplified fragment length polymorphism and PCR ribotyping. J Clin Microbiol (2004) 1.73

Interlaboratory evaluation of different extraction and real-time PCR methods for detection of Coxiella burnetii DNA in serum. J Clin Microbiol (2010) 1.65

Clostridium difficile PCR ribotype 078 toxinotype V found in diarrhoeal pigs identical to isolates from affected humans. Environ Microbiol (2009) 1.65

Multigenotype Q fever outbreak, the Netherlands. Emerg Infect Dis (2009) 1.63

Molecular epidemiology of Aspergillus fumigatus isolates recovered from water, air, and patients shows two clusters of genetically distinct strains. J Clin Microbiol (2003) 1.59

MRSA genotypes in Turkey: persistence over 10 years of a single clone of ST239. J Infect (2009) 1.50

Tuberculin skin testing is useful in the screening for nontuberculous mycobacterial cervicofacial lymphadenitis in children. Clin Infect Dis (2006) 1.49

Genotypic diversity of Coxiella burnetii in the 2007-2010 Q fever outbreak episodes in The Netherlands. J Clin Microbiol (2011) 1.49

Rapid induction of multiple resistance mechanisms in Aspergillus fumigatus during azole therapy: a case study and review of the literature. Antimicrob Agents Chemother (2011) 1.49

Laboratory-acquired clostridium difficile polymerase chain reaction ribotype 027: a new risk for laboratory workers? Clin Infect Dis (2008) 1.48

Evaluation of 12 commercial tests and the complement fixation test for Mycoplasma pneumoniae-specific immunoglobulin G (IgG) and IgM antibodies, with PCR used as the "gold standard". J Clin Microbiol (2005) 1.45

Pneumolysin is a key factor in misidentification of macrolide-resistant Streptococcus pneumoniae and is a putative virulence factor of S. mitis and other streptococci. J Clin Microbiol (2004) 1.44

In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates. Antimicrob Agents Chemother (2010) 1.41

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. PLoS One (2012) 1.40

Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics. J Antimicrob Chemother (2011) 1.39

Procalcitonin reflects bacteremia and bacterial load in urosepsis syndrome: a prospective observational study. Crit Care (2010) 1.38

Detection of a point mutation associated with high-level isoniazid resistance in Mycobacterium tuberculosis by using real-time PCR technology with 3'-minor groove binder-DNA probes. J Clin Microbiol (2003) 1.37

Epidemic genotype of Coxiella burnetii among goats, sheep, and humans in the Netherlands. Emerg Infect Dis (2012) 1.32

Qiagen DNA extraction kits for sample preparation for legionella PCR are not suitable for diagnostic purposes. J Clin Microbiol (2002) 1.31

All-cause and disease-specific mortality in hospitalized patients with Clostridium difficile infection: a multicenter cohort study. Clin Infect Dis (2013) 1.26

Cervicofacial lymphadenitis in children caused by Mycobacterium haemophilum. Clin Infect Dis (2005) 1.21

Adaptive evolution of Staphylococcus aureus during chronic endobronchial infection of a cystic fibrosis patient. PLoS One (2011) 1.17

Molecular epidemiology of Aspergillus fumigatus isolates harboring the TR34/L98H azole resistance mechanism. J Clin Microbiol (2012) 1.16

Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest. PLoS One (2013) 1.15

Lack of value of routine analysis of cerebrospinal fluid for prediction and diagnosis of external drainage-related bacterial meningitis. J Neurosurg (2006) 1.13

Autochthonous and dormant Cryptococcus gattii infections in Europe. Emerg Infect Dis (2012) 1.13

The dominance of human coronavirus OC43 and NL63 infections in infants. J Clin Virol (2011) 1.12

Comparative analysis of an expanded Clostridium difficile reference strain collection reveals genetic diversity and evolution through six lineages. Infect Genet Evol (2012) 1.12

Utility of a microsatellite assay for identifying clonally related outbreak isolates of Aspergillus fumigatus. J Microbiol Methods (2008) 1.11

Microsatellite typing of clinical and environmental Cryptococcus neoformans var. grubii isolates from Cuba shows multiple genetic lineages. PLoS One (2010) 1.10

Comparison of two highly discriminatory molecular fingerprinting assays for analysis of multiple Aspergillus fumigatus isolates from patients with invasive aspergillosis. J Clin Microbiol (2007) 1.10

Microsatellite based typing of Aspergillus fumigatus: strengths, pitfalls and solutions. J Microbiol Methods (2007) 1.10

Use of amplified fragment length polymorphism to identify 42 Cladophialophora strains related to cerebral phaeohyphomycosis with in vitro antifungal susceptibility. J Clin Microbiol (2010) 1.09

Prospective study of respiratory viral infections in pediatric hemopoietic stem cell transplantation patients. Pediatr Infect Dis J (2004) 1.07

Typing Clostridium difficile strains based on tandem repeat sequences. BMC Microbiol (2009) 1.06

Comparison of mumps-IgM ELISAs in acute infection. J Clin Virol (2006) 1.05

Clostridium difficile: controversies and approaches to management. Curr Opin Infect Dis (2009) 1.04

Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection? Clin Infect Dis (2008) 1.03

TcdC does not significantly repress toxin expression in Clostridium difficile 630ΔErm. PLoS One (2012) 1.02

Genotyping reveals the presence of a predominant genotype of Coxiella burnetii in consumer milk products. J Clin Microbiol (2012) 1.02

Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters. J Neurosurg (2005) 1.02

Clinical outcomes and macrolide resistance in Mycoplasma pneumoniae infection in Scotland, UK. J Med Microbiol (2013) 1.02

Risk factors for bacteremia with uropathogen not cultured from urine in adults with febrile urinary tract infection. Clin Infect Dis (2010) 1.00

Bovine antibody-enriched whey to aid in the prevention of a relapse of Clostridium difficile-associated diarrhoea: preclinical and preliminary clinical data. J Med Microbiol (2005) 0.99

Genotypic diversity of clinical Coxiella burnetii isolates from Portugal based on MST and MLVA typing. Int J Med Microbiol (2012) 0.99

Molecular epidemiology and evolution of human respiratory syncytial virus and human metapneumovirus. PLoS One (2011) 0.99

Molecular epidemiology of Aspergillus fumigatus: an in-depth genotypic analysis of isolates involved in an outbreak of invasive aspergillosis. J Clin Microbiol (2011) 0.99

Oral bacteria and yeasts in relationship to oral ulcerations in hematopoietic stem cell transplant recipients. Support Care Cancer (2012) 0.98

C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA. PLoS One (2012) 0.98

Inter-laboratory comparison of three different real-time PCR assays for the detection of Pneumocystis jiroveci in bronchoalveolar lavage fluid samples. J Med Microbiol (2006) 0.98

Circulating DNA is a non-invasive prognostic factor for survival in non-small cell lung cancer. Lung Cancer (2009) 0.98

Genetic markers for Clostridium difficile lineages linked to hypervirulence. Microbiology (2011) 0.97

Antimicrobial-resistant pathogens in animals and man: prescribing, practices and policies. J Antimicrob Chemother (2010) 0.97

Geographically structured populations of Cryptococcus neoformans Variety grubii in Asia correlate with HIV status and show a clonal population structure. PLoS One (2013) 0.96

High prevalence of Clostridium difficile colonization among nursing home residents in Hesse, Germany. PLoS One (2012) 0.96

Clostridium difficile PCR ribotype 176 in the Czech Republic and Poland. Lancet (2011) 0.94

Genotyping of Coxiella burnetii from domestic ruminants in northern Spain. BMC Vet Res (2012) 0.94

Prevalence of Clostridium difficile in retailed meat in the Netherlands. Int J Food Microbiol (2010) 0.93

Detection of respiratory pathogens by real-time PCR in children with clinical suspicion of pertussis. Eur J Pediatr (2006) 0.93

An in vitro study on the active conversion of flucytosine to fluorouracil by microorganisms in the human intestinal microflora. Chemotherapy (2003) 0.93

The sonographic characteristics of nontuberculous mycobacterial cervicofacial lymphadenitis in children. Pediatr Radiol (2006) 0.93

Amplified fragment length polymorphism fingerprinting is an effective technique to distinguish streptococcus pneumoniae from other Streptococci and an efficient alternative to pulsed-field gel electrophoresis for molecular typing of pneumococci. J Clin Microbiol (2004) 0.93

Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications. J Antimicrob Chemother (2013) 0.92

Treatment duration of febrile urinary tract infection (FUTIRST trial): a randomized placebo-controlled multicenter trial comparing short (7 days) antibiotic treatment with conventional treatment (14 days). BMC Infect Dis (2009) 0.92

Clinical Staphylococcus aureus isolate negative for the Sa442 fragment. J Clin Microbiol (2003) 0.92

First report of Atopobium vaginae bacteremia with fetal loss after chorionic villus sampling. J Clin Microbiol (2011) 0.91

High resolution genotyping of clinical Aspergillus flavus isolates from India using microsatellites. PLoS One (2011) 0.91

Novel risk factors for Clostridium difficile-associated disease in a setting of endemicity? Clin Infect Dis (2008) 0.90

Molecular typing and colonization patterns of Aspergillus fumigatus in patients with cystic fibrosis. J Cyst Fibros (2008) 0.90

Microsatellite typing and susceptibilities of serial Cryptococcus neoformans isolates from Cuban patients with recurrent cryptococcal meningitis. BMC Infect Dis (2010) 0.90

Multicenter collaborative study for standardization of Candida albicans genotyping using a polymorphic microsatellite marker. J Clin Microbiol (2010) 0.90

Search for possible additional reservoirs for human Q fever, The Netherlands. Emerg Infect Dis (2013) 0.90

Extensive genetic diversity within the Dutch clinical Cryptococcus neoformans population. J Clin Microbiol (2012) 0.89

Resistance of Asian Cryptococcus neoformans serotype A is confined to few microsatellite genotypes. PLoS One (2012) 0.88