Published in BMC Genomics on January 31, 2015
Diversity and Evolution in the Genome of Clostridium difficile. Clin Microbiol Rev (2015) 0.94
A roadmap for gene system development in Clostridium. Anaerobe (2016) 0.91
Near-Complete Genome Sequence of Clostridium paradoxum Strain JW-YL-7. Genome Announc (2016) 0.88
Regulation of Type IV Pili Contributes to Surface Behaviors of Historical and Epidemic Strains of Clostridium difficile. J Bacteriol (2015) 0.79
Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630. Genome Announc (2015) 0.78
New Insights into the Classification and Integration Specificity of Streptococcus Integrative Conjugative Elements through Extensive Genome Exploration. Front Microbiol (2016) 0.77
What's a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives. Virulence (2016) 0.76
A genetic switch controls the production of flagella and toxins in Clostridium difficile. PLoS Genet (2017) 0.75
Clostridioides difficile 630Δerm in silico and in vivo - quantitative growth and extensive polysaccharide secretion. FEBS Open Bio (2017) 0.75
Interspecies Interactions between Clostridium difficile and Candida albicans. mSphere (2016) 0.75
Analysis of the Core Genome and Pan-Genome of Autotrophic Acetogenic Bacteria. Front Microbiol (2016) 0.75
Determining Clostridium difficile intra-taxa diversity by mining multilocus sequence typing databases. BMC Microbiol (2017) 0.75
Use of single molecule sequencing for comparative genomics of an environmental and a clinical isolate of Clostridium difficile ribotype 078. BMC Genomics (2016) 0.75
SNP-ing out the differences: Investigating differences between Clostridium difficile lab strains. Virulence (2016) 0.75
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
Versatile and open software for comparing large genomes. Genome Biol (2004) 49.45
Artemis: sequence visualization and annotation. Bioinformatics (2000) 46.68
Circos: an information aesthetic for comparative genomics. Genome Res (2009) 40.02
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data. Nat Methods (2013) 31.15
progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement. PLoS One (2010) 24.31
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform (2012) 23.58
Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat Methods (2010) 9.75
Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads. Genome Res (2010) 9.55
Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database. Bioinformatics (2008) 9.17
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02
Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol (2009) 7.89
High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies. PLoS Genet (2008) 4.86
DREME: motif discovery in transcription factor ChIP-seq data. Bioinformatics (2011) 4.71
Gepard: a rapid and sensitive tool for creating dotplots on genome scale. Bioinformatics (2007) 4.45
The ClosTron: a universal gene knock-out system for the genus Clostridium. J Microbiol Methods (2007) 4.20
Mind the gap: upgrading genomes with Pacific Biosciences RS long-read sequencing technology. PLoS One (2012) 4.18
Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat Genet (2012) 4.10
Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A (2010) 3.18
Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol (2006) 3.05
Investigation of an outbreak of antibiotic-associated colitis by various typing methods. J Clin Microbiol (1982) 2.86
The origins of 168, W23, and other Bacillus subtilis legacy strains. J Bacteriol (2008) 2.86
N6-methyl-adenine: an epigenetic signal for DNA-protein interactions. Nat Rev Microbiol (2006) 2.75
Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol (2006) 2.65
Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and more. FEMS Microbiol Rev (2009) 2.41
Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier. Mol Microbiol (2002) 2.19
Dam methylation: coordinating cellular processes. Curr Opin Microbiol (2005) 2.11
Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites. J Med Microbiol (2005) 2.09
Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis. J Clin Microbiol (2006) 1.87
Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production. Appl Environ Microbiol (2012) 1.70
Genetic analysis of a tetracycline resistance element from Clostridium difficile and its conjugal transfer to and from Bacillus subtilis. J Gen Microbiol (1990) 1.57
N6-methyladenine: the other methylated base of DNA. Bioessays (2006) 1.50
Tn916-like genetic elements: a diverse group of modular mobile elements conferring antibiotic resistance. FEMS Microbiol Rev (2011) 1.45
Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes (2012) 1.33
A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein. Mol Microbiol (2009) 1.30
Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile. PLoS One (2011) 1.29
Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles. PLoS One (2013) 1.23
Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. Nucleic Acids Res (2003) 1.22
Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli. J Biol Chem (2002) 1.22
Clostridium difficile toxins: mediators of inflammation. J Innate Immun (2012) 1.21
Clostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes (2010) 1.19
Spatial regulation of histidine kinases governing biofilm formation in Bacillus subtilis. J Bacteriol (2010) 1.16
The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. PLoS Pathog (2011) 1.11
Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers. Nat Commun (2013) 1.08
The mosaic nature of intergenic 16S-23S rRNA spacer regions suggests rRNA operon copy number variation in Clostridium difficile strains. Appl Environ Microbiol (2006) 1.08
Epigenetic regulation of the bacterial cell cycle. Curr Opin Microbiol (2009) 1.06
C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA. PLoS One (2012) 0.98
In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes. Mob Genet Elements (2012) 0.94
Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism. BMC Genomics (2014) 0.93
Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA. Biochem Biophys Res Commun (2010) 0.92
Demonstration of conjugative transposon (Tn5397)-mediated horizontal gene transfer between Clostridium difficile and Enterococcus faecalis. Antimicrob Agents Chemother (2010) 0.88
Gene transfer into Clostridium difficile CD630 and characterisation of its methylase genes. FEMS Microbiol Lett (2003) 0.83
Hype or hypervirulence: a reflection on problematic C. difficile strains. Virulence (2013) 0.83
The HtrA-like protease CD3284 modulates virulence of Clostridium difficile. Infect Immun (2014) 0.77
New opportunities for improved ribotyping of C. difficile clinical isolates by exploring their genomes. J Microbiol Methods (2013) 0.77