Published in Endocrinology on December 21, 2006
p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix. J Biol Chem (2010) 1.18
Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice. BMC Dev Biol (2010) 1.11
Bioreactors to influence stem cell fate: augmentation of mesenchymal stem cell signaling pathways via dynamic culture systems. Biochim Biophys Acta (2012) 1.07
Calcium-mediated stress kinase activation by DMP1 promotes osteoblast differentiation. J Biol Chem (2010) 1.06
Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity. Proc Natl Acad Sci U S A (2010) 1.03
p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. J Clin Invest (2012) 0.90
Disruption of prostate epithelial differentiation pathways and prostate cancer development. Front Oncol (2013) 0.89
Effect of phosphatidyl inositol 3-kinase, extracellular signal-regulated kinases 1/2, and p38 mitogen-activated protein kinase inhibition on osteogenic differentiation of muscle-derived stem cells. Tissue Eng Part A (2010) 0.87
BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic mice. Endocrinology (2013) 0.87
Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties. J Biol Chem (2012) 0.87
Protein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expression. PLoS One (2009) 0.86
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects. PLoS One (2012) 0.85
PDGF-AA promotes osteogenic differentiation and migration of mesenchymal stem cell by down-regulating PDGFRα and derepressing BMP-Smad1/5/8 signaling. PLoS One (2014) 0.84
p53 regulates neural stem cell proliferation and differentiation via BMP-Smad1 signaling and Id1. Stem Cells Dev (2013) 0.84
The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice. PLoS One (2014) 0.81
TGF-β Signaling Regulates Cementum Formation through Osterix Expression. Sci Rep (2016) 0.78
Rap1A Regulates Osteoblastic Differentiation via the ERK and p38 Mediated Signaling. PLoS One (2015) 0.78
p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. Stem Cell Reports (2016) 0.77
NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts. Arthritis Res Ther (2013) 0.77
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet (2012) 2.02
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet (2011) 1.88
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. J Cell Biol (2005) 1.86
Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell (2006) 1.54
Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling. J Biol Chem (2007) 1.53
Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell (2002) 1.37
Activation of p38 mitogen-activated protein kinase is required for osteoblast differentiation. Endocrinology (2003) 1.25
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response. EMBO J (2010) 1.18
ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress. Mol Biol Cell (2005) 1.11
Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress. Cancer Res (2007) 1.09
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem Biophys Res Commun (2003) 1.05
Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis. Hum Mol Genet (2006) 1.04
Common variants near TERC are associated with leukocyte telomere length in the Chinese Han population. Eur J Hum Genet (2011) 0.95
Identification of aberrant microRNA expression pattern in pediatric gliomas by microarray. Diagn Pathol (2013) 0.94
p53 Deficiency leads to compensatory up-regulation of p16INK4a. Mol Cancer Res (2009) 0.93
A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. Nat Commun (2012) 0.92
c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression. Nat Cell Biol (2012) 0.92
Common SNPs in myelin transcription factor 1-like (MYT1L): association with major depressive disorder in the Chinese Han population. PLoS One (2010) 0.92
Mdm2 links genotoxic stress and metabolism to p53. Protein Cell (2011) 0.92
Identification of TopBP1 as a c-Abl-interacting protein and a repressor for c-Abl expression. J Biol Chem (2005) 0.87
Protein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expression. PLoS One (2009) 0.86
PKCdelta mediates Nrf2-dependent protection of neuronal cells from NO-induced apoptosis. Biochem Biophys Res Commun (2009) 0.85
Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis. PLoS One (2008) 0.85
p53 regulates neural stem cell proliferation and differentiation via BMP-Smad1 signaling and Id1. Stem Cells Dev (2013) 0.84
PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. Cell Signal (2006) 0.83
Atypical Atm-p53 genetic interaction in osteogenesis is mediated by Smad1 signaling. J Mol Cell Biol (2012) 0.82
p53 control of bone remodeling. J Cell Biochem (2010) 0.81
Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis. Mol Cancer (2013) 0.80
Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential. PLoS One (2013) 0.80
Common SNPs in CSF2RB are associated with major depression and schizophrenia in the Chinese Han population. World J Biol Psychiatry (2011) 0.80
Regulation of hTERT by BCR-ABL at multiple levels in K562 cells. BMC Cancer (2011) 0.80
Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients. Fertil Steril (2010) 0.80
Novel mechanism of transcriptional regulation of cell matrix protein through CREB. Cell Cycle (2015) 0.77
Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population. World J Biol Psychiatry (2010) 0.77
Overexpression of Wnt5a in mouse epidermis causes no psoriasis phenotype but an impairment of hair follicle anagen development. Exp Dermatol (2014) 0.77
An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression. J Cell Biochem (2014) 0.77
A role for c-Abl in cell senescence and spontaneous immortalization. Age (Dordr) (2012) 0.75
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. J Clin Invest (2017) 0.75
Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodeling. Int J Biomed Sci (2007) 0.75
Smad1 stabilization and delocalization in response to the blockade of BMP activity. Cell Mol Biol Lett (2013) 0.75