PubRank

Klaus-Armin Nave

Author PubWeight™ 174.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Axonal neuregulin-1 regulates myelin sheath thickness. Science 2004 6.09
2 Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat Genet 2003 5.43
3 Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 2008 5.15
4 The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron 2006 4.12
5 Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature 2012 3.09
6 Axonal transport defects in neurodegenerative diseases. J Neurosci 2009 2.74
7 Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol 2013 2.61
8 Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis 2006 2.52
9 Neurod1 is essential for the survival and maturation of adult-born neurons. Nat Neurosci 2009 2.38
10 High cholesterol level is essential for myelin membrane growth. Nat Neurosci 2005 2.34
11 Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet 2007 2.30
12 Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J Neurosci 2005 2.27
13 Axonal prion protein is required for peripheral myelin maintenance. Nat Neurosci 2010 2.25
14 Monitoring regulated protein-protein interactions using split TEV. Nat Methods 2006 2.24
15 Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A). Nat Med 2003 2.17
16 Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. J Cell Biol 2009 1.97
17 Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci 2010 1.93
18 Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab 2010 1.88
19 Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. Proc Natl Acad Sci U S A 2005 1.77
20 Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol 2007 1.69
21 Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol 2002 1.65
22 Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science 2011 1.64
23 Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Proteomics Clin Appl 2007 1.58
24 Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci 2007 1.58
25 Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron 2010 1.57
26 Global transcriptome analysis of genetically identified neurons in the adult cortex. J Neurosci 2006 1.55
27 Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci 2009 1.54
28 Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. J Cell Biol 2006 1.49
29 A role for Schwann cell-derived neuregulin-1 in remyelination. Nat Neurosci 2012 1.47
30 Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex. J Neurosci 2007 1.45
31 Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation. Glia 2008 1.45
32 FAK is required for axonal sorting by Schwann cells. J Cell Biol 2007 1.43
33 Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain 2007 1.42
34 Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination. Mol Cell Biol 2004 1.40
35 Arrest of myelination and reduced axon growth when Schwann cells lack mTOR. J Neurosci 2012 1.39
36 Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum Mol Genet 2003 1.32
37 Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models. J Lipid Res 2010 1.31
38 Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice. PLoS One 2008 1.28
39 Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease. J Cell Biol 2002 1.27
40 Calcium activation of the LMO4 transcription complex and its role in the patterning of thalamocortical connections. J Neurosci 2006 1.27
41 Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci. J Neurosci 2011 1.26
42 Evolution of a neuroprotective function of central nervous system myelin. J Cell Biol 2006 1.25
43 Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metab 2011 1.25
44 Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1. Glia 2009 1.25
45 Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination. Glia 2007 1.22
46 CNP is required for maintenance of axon-glia interactions at nodes of Ranvier in the CNS. Glia 2005 1.22
47 Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci 2006 1.22
48 Hippocampal cGMP-dependent protein kinase I supports an age- and protein synthesis-dependent component of long-term potentiation but is not essential for spatial reference and contextual memory. J Neurosci 2003 1.20
49 Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. J Neurosci 2006 1.20
50 A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord. Dev Biol 2008 1.19
51 Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy. Ann Neurol 2007 1.18
52 Fibroblast growth factor receptor signaling in oligodendrocytes regulates myelin sheath thickness. J Neurosci 2012 1.17
53 The role of myelin and oligodendrocytes in axonal energy metabolism. Curr Opin Neurobiol 2013 1.17
54 Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy. EMBO Mol Med 2012 1.17
55 Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. Arch Gen Psychiatry 2010 1.17
56 Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination. J Neurosci 2006 1.16
57 The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. J Biol Chem 2002 1.16
58 A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease. Proc Natl Acad Sci U S A 2007 1.12
59 NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse. Genesis 2008 1.12
60 The role of CNS glia in preserving axon function. Curr Opin Neurobiol 2009 1.12
61 Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction. J Neurosci 2009 1.12
62 Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. Neurogenetics 2009 1.10
63 The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients. BMC Psychiatry 2010 1.10
64 Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes. Genesis 2004 1.09
65 Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2. Genesis 2005 1.08
66 SHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBP. EMBO Rep 2008 1.08
67 Early neuronal and glial fate restriction of embryonic neural stem cells. J Neurosci 2008 1.07
68 Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles. EMBO J 2013 1.06
69 Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia. J Neurosci 2006 1.05
70 Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection. Neuron Glia Biol 2009 1.04
71 Misalignment of PLP/DM20 transmembrane domains determines protein misfolding in Pelizaeus-Merzbacher disease. J Neurosci 2011 1.04
72 Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia 2011 1.04
73 Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. J Pineal Res 2006 1.04
74 A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain. Proc Natl Acad Sci U S A 2005 1.03
75 Animal models of inherited neuropathies. Curr Opin Neurol 2006 1.02
76 Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence. Mol Cell Neurosci 2005 1.01
77 Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. Neurobiol Dis 2006 1.01
78 A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia. EMBO Mol Med 2011 1.00
79 Subtle myelin defects in PLP-null mice. Glia 2006 1.00
80 Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet. Nat Med 2012 0.98
81 Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves. Mol Cell Neurosci 2002 0.97
82 A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system. Glia 2013 0.97
83 Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. J Neurosci 2009 0.97
84 Neuron-glia signaling and the protection of axon function by Schwann cells. J Peripher Nerv Syst 2010 0.97
85 Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells. J Biol Chem 2008 0.96
86 Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proc Natl Acad Sci U S A 2009 0.95
87 Oligodendroglial impact on axonal function and survival - a hypothesis. Curr Opin Neurol 2008 0.94
88 Palmitoylation is a sorting determinant for transport to the myelin membrane. J Cell Sci 2005 0.94
89 Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease. EMBO Mol Med 2010 0.94
90 The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia. J Neurosci Res 2009 0.94
91 Cholesterol: a novel regulatory role in myelin formation. Neuroscientist 2011 0.93
92 A myelin gene causative of a catatonia-depression syndrome upon aging. EMBO Mol Med 2012 0.92
93 Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7. J Neurosci 2011 0.92
94 PD-1 regulates neural damage in oligodendroglia-induced inflammation. PLoS One 2009 0.92
95 Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation. Neurobiol Dis 2013 0.91
96 PLP/DM20 expression and turnover in a transgenic mouse model of Pelizaeus-Merzbacher disease. Glia 2010 0.90
97 Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cereb Cortex 2011 0.90
98 Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy. Orphanet J Rare Dis 2014 0.89
99 Adapting brain metabolism to myelination and long-range signal transduction. Glia 2014 0.89
100 Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia 2013 0.89
101 Survival of adult neurons lacking cholesterol synthesis in vivo. BMC Neurosci 2007 0.88
102 Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A 2013 0.88
103 Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia. J Neurosci 2013 0.87
104 Structure and composition of myelinated axons: a multimodal synchrotron spectro-microscopy study. J Struct Biol 2010 0.87
105 Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants. Am J Pathol 2009 0.86
106 Proliferation of Schwann cells and regulation of cyclin D1 expression in an animal model of Charcot-Marie-Tooth disease type 1A. J Neurosci Res 2002 0.86
107 Genetic tracing of subpopulation neurons in the prethalamus of mice (Mus musculus). J Comp Neurol 2009 0.85
108 Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice. BMC Biol 2011 0.85
109 Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions. J Neurosci 2013 0.85
110 Critical time window of neuronal cholesterol synthesis during neurite outgrowth. J Neurosci 2012 0.85
111 The C264Y missense mutation in the extracellular domain of L1 impairs protein trafficking in vitro and in vivo. J Neurosci 2003 0.85
112 Experimental Charcot-Marie-Tooth type 1A: a cDNA microarrays analysis. Mol Cell Neurosci 2005 0.84
113 Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes. Glia 2010 0.84
114 Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system. Proc Natl Acad Sci U S A 2013 0.84
115 A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity. FEBS Lett 2011 0.83
116 Different proteolipid protein mutants exhibit unique metabolic defects. ASN Neuro 2009 0.83
117 Neuroinflammation in white matter tracts of Cnp1 mutant mice amplified by a minor brain injury. Glia 2013 0.82
118 Why do oligodendrocyte lineage cells express glutamate receptors? F1000 Biol Rep 2010 0.82
119 Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice. J Neurosci 2005 0.82
120 Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. PLoS One 2012 0.81
121 Normal metabolism but different physical properties of myelin from mice deficient in proteolipid protein. J Neurosci Res 2003 0.81
122 A phenotype-based genetic association study reveals the contribution of neuregulin1 gene variants to age of onset and positive symptom severity in schizophrenia. Am J Med Genet B Neuropsychiatr Genet 2011 0.81
123 Common variants of the genes encoding erythropoietin and its receptor modulate cognitive performance in schizophrenia. Mol Med 2012 0.81
124 Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease. Eur J Neurosci 2006 0.80
125 Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. Am J Pathol 2009 0.80
126 STAT3 represents a molecular switch possibly inducing astroglial instead of oligodendroglial differentiation of oligodendroglial progenitor cells in Theiler's murine encephalomyelitis. Neuropathol Appl Neurobiol 2015 0.80
127 In vivo imaging and noninvasive ablation of pyramidal neurons in adult NEX-CreERT2 mice. Cereb Cortex 2011 0.80
128 Myelin disorders: Causes and perspectives of Charcot-Marie-Tooth neuropathy. J Mol Neurosci 2006 0.79
129 Neuroscience: An ageing view of myelin repair. Nature 2008 0.79
130 Profilin 1 is required for peripheral nervous system myelination. Development 2014 0.79
131 Episode-specific differential gene expression of peripheral blood mononuclear cells in rapid cycling supports novel treatment approaches. Mol Med 2008 0.79
132 Early abnormalities in sciatic nerve function and structure in a rat model of Charcot-Marie-Tooth type 1A disease. Exp Neurol 2004 0.77
133 Modulation of rumpshaker phenotype with wild-type PLP/DM20 suggests several pathogenic mechanisms. J Neurosci Res 2010 0.77
134 Molecular triggers of neuroinflammation in mouse models of demyelinating diseases. Biol Chem 2013 0.77
135 Glial cells under remote control. Nat Neurosci 2005 0.76