Published in Glia on November 01, 2008
Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med (2012) 2.56
Signals to promote myelin formation and repair. Nat Rev Neurol (2010) 1.95
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
Nrg1/ErbB signaling networks in Schwann cell development and myelination. Semin Cell Dev Biol (2010) 1.49
A role for Schwann cell-derived neuregulin-1 in remyelination. Nat Neurosci (2012) 1.47
Specific functions for ERK/MAPK signaling during PNS development. Neuron (2011) 1.45
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Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly. Prog Neurobiol (2011) 1.23
Molecular evidence for differences in endometrium in severe versus mild endometriosis. Reprod Sci (2010) 1.16
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The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer's Disease and Beyond. Front Physiol (2012) 1.09
Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling. J Neurosci (2010) 1.06
ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma. Neuro Oncol (2010) 1.04
Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia (2011) 1.04
Neuronal Neuregulin 1 type III directs Schwann cell migration. Development (2011) 0.99
Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation. J Biol Chem (2010) 0.98
Neuregulin 1-erbB4 pathway in schizophrenia: From genes to an interactome. Brain Res Bull (2010) 0.97
Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars. Proc Natl Acad Sci U S A (2009) 0.95
Repair of the Peripheral Nerve-Remyelination that Works. Brain Sci (2013) 0.94
The actin-severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination. J Neurosci (2012) 0.93
Opposing roles of PKA and EPAC in the cAMP-dependent regulation of schwann cell proliferation and differentiation [corrected]. PLoS One (2013) 0.93
Critical period of axoglial signaling between neuregulin-1 and brain-derived neurotrophic factor required for early Schwann cell survival and differentiation. J Neurosci (2011) 0.92
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination. Brain (2013) 0.90
Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development (2011) 0.90
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A (2013) 0.88
Nerve physiology: mechanisms of injury and recovery. Hand Clin (2013) 0.87
Jab1 regulates Schwann cell proliferation and axonal sorting through p27. J Exp Med (2013) 0.85
Requirement of cAMP signaling for Schwann cell differentiation restricts the onset of myelination. PLoS One (2015) 0.83
Genetic dissection of myelinated axons in zebrafish. Curr Opin Neurobiol (2009) 0.82
Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44. Mol Cell Biol (2015) 0.82
New insights into signaling during myelination in zebrafish. Curr Top Dev Biol (2011) 0.80
Neuropathologic implication of peripheral neuregulin-1 and EGF signals in dopaminergic dysfunction and behavioral deficits relevant to schizophrenia: their target cells and time window. Biomed Res Int (2014) 0.80
Advances and Future Applications of Augmented Peripheral Nerve Regeneration. Int J Mol Sci (2016) 0.80
Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration. Front Mol Neurosci (2016) 0.79
Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One (2014) 0.79
Age-related neuronal loss in the cochlea is not delayed by synaptic modulation. Neurobiol Aging (2010) 0.79
Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS. Development (2016) 0.78
Schwann cells migrate along axons in the absence of GDNF signaling. BMC Neurosci (2012) 0.78
Cthrc1 is a negative regulator of myelination in Schwann cells. Glia (2012) 0.76
The use of brief post-surgical low frequency electrical stimulation to enhance nerve regeneration in clinical practice. J Physiol (2016) 0.76
Glutamate signals through mGluR2 to control Schwann cell differentiation and proliferation. Sci Rep (2016) 0.76
Neural and molecular features on Charcot-Marie-Tooth disease plasticity and therapy. Neural Plast (2012) 0.76
NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers. Glia (2017) 0.75
Myelin sheaths are formed with proteins that originated in vertebrate lineages. Neuron Glia Biol (2008) 0.75
Expression pattern of neuregulin-1 type III during the development of the peripheral nervous system. Neural Regen Res (2015) 0.75
Structural Similarities Between Neuregulin 1-3 Isoforms Determine their Subcellular Distribution and Signaling Mode in Central Neurons. J Neurosci (2017) 0.75
BACE1 regulates the proliferation and cellular functions of Schwann cells. Glia (2017) 0.75
Iron homeostasis in peripheral nervous system, still a black box? Antioxid Redox Signal (2014) 0.75
A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles. J Neurosci (2016) 0.75
Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Sci Rep (2017) 0.75
The role of nerve microenvironment for neurofibroma development. Oncotarget (2016) 0.75
A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin. PLoS One (2010) 0.75
The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells. Int J Biochem Cell Biol (2015) 0.75
Lithium Reversibly Inhibits Schwann Cell Proliferation and Differentiation Without Inducing Myelin Loss. Mol Neurobiol (2016) 0.75
Myelination in coculture of established neuronal and Schwann cell lines. Histochem Cell Biol (2012) 0.75
Axonal neuregulin-1 regulates myelin sheath thickness. Science (2004) 6.09
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat Genet (2003) 5.43
Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci (2008) 5.15
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature (2012) 3.09
Axonal transport defects in neurodegenerative diseases. J Neurosci (2009) 2.74
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis (2006) 2.52
Neurod1 is essential for the survival and maturation of adult-born neurons. Nat Neurosci (2009) 2.38
High cholesterol level is essential for myelin membrane growth. Nat Neurosci (2005) 2.34
Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet (2007) 2.30
Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J Neurosci (2005) 2.27
Axonal prion protein is required for peripheral myelin maintenance. Nat Neurosci (2010) 2.25
Monitoring regulated protein-protein interactions using split TEV. Nat Methods (2006) 2.24
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A). Nat Med (2003) 2.17
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. J Cell Biol (2009) 1.97
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci (2010) 1.93
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab (2010) 1.88
Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. Proc Natl Acad Sci U S A (2005) 1.77
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol (2007) 1.69
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (2011) 1.64
Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Proteomics Clin Appl (2007) 1.58
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron (2010) 1.57
Global transcriptome analysis of genetically identified neurons in the adult cortex. J Neurosci (2006) 1.55
Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci (2009) 1.54
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. J Cell Biol (2006) 1.49
A role for Schwann cell-derived neuregulin-1 in remyelination. Nat Neurosci (2012) 1.47
Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex. J Neurosci (2007) 1.45
FAK is required for axonal sorting by Schwann cells. J Cell Biol (2007) 1.43
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain (2007) 1.42
Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination. Mol Cell Biol (2004) 1.40
Arrest of myelination and reduced axon growth when Schwann cells lack mTOR. J Neurosci (2012) 1.39
Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum Mol Genet (2003) 1.32
Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models. J Lipid Res (2010) 1.31
Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant mice. PLoS One (2008) 1.28
Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease. J Cell Biol (2002) 1.27
Calcium activation of the LMO4 transcription complex and its role in the patterning of thalamocortical connections. J Neurosci (2006) 1.27
Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci. J Neurosci (2011) 1.26
Evolution of a neuroprotective function of central nervous system myelin. J Cell Biol (2006) 1.25
Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1. Glia (2009) 1.25
Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metab (2011) 1.25
CNP is required for maintenance of axon-glia interactions at nodes of Ranvier in the CNS. Glia (2005) 1.22
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci (2006) 1.22
Hippocampal cGMP-dependent protein kinase I supports an age- and protein synthesis-dependent component of long-term potentiation but is not essential for spatial reference and contextual memory. J Neurosci (2003) 1.20
Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. J Neurosci (2006) 1.20
A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord. Dev Biol (2008) 1.19
Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy. Ann Neurol (2007) 1.18
Fibroblast growth factor receptor signaling in oligodendrocytes regulates myelin sheath thickness. J Neurosci (2012) 1.17
The role of myelin and oligodendrocytes in axonal energy metabolism. Curr Opin Neurobiol (2013) 1.17
Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy. EMBO Mol Med (2012) 1.17
Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. Arch Gen Psychiatry (2010) 1.17
Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination. J Neurosci (2006) 1.16
The role of CNS glia in preserving axon function. Curr Opin Neurobiol (2009) 1.12
A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease. Proc Natl Acad Sci U S A (2007) 1.12
NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse. Genesis (2008) 1.12
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction. J Neurosci (2009) 1.12
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models. Neurogenetics (2009) 1.10
The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients. BMC Psychiatry (2010) 1.10
Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes. Genesis (2004) 1.09
Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2. Genesis (2005) 1.08
SHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBP. EMBO Rep (2008) 1.08
Early neuronal and glial fate restriction of embryonic neural stem cells. J Neurosci (2008) 1.07
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles. EMBO J (2013) 1.06
Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia. J Neurosci (2006) 1.05
Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection. Neuron Glia Biol (2009) 1.04
Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia (2011) 1.04
Misalignment of PLP/DM20 transmembrane domains determines protein misfolding in Pelizaeus-Merzbacher disease. J Neurosci (2011) 1.04
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. J Pineal Res (2006) 1.04
A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain. Proc Natl Acad Sci U S A (2005) 1.03
Animal models of inherited neuropathies. Curr Opin Neurol (2006) 1.02
Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence. Mol Cell Neurosci (2005) 1.01
Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. Neurobiol Dis (2006) 1.01
A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia. EMBO Mol Med (2011) 1.00
Subtle myelin defects in PLP-null mice. Glia (2006) 1.00
Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet. Nat Med (2012) 0.98
Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. J Neurosci (2009) 0.97
A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system. Glia (2013) 0.97
Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves. Mol Cell Neurosci (2002) 0.97
Neuron-glia signaling and the protection of axon function by Schwann cells. J Peripher Nerv Syst (2010) 0.97
Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells. J Biol Chem (2008) 0.96
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proc Natl Acad Sci U S A (2009) 0.95
Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease. EMBO Mol Med (2010) 0.94
The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia. J Neurosci Res (2009) 0.94
Oligodendroglial impact on axonal function and survival - a hypothesis. Curr Opin Neurol (2008) 0.94
Palmitoylation is a sorting determinant for transport to the myelin membrane. J Cell Sci (2005) 0.94
Cholesterol: a novel regulatory role in myelin formation. Neuroscientist (2011) 0.93
A myelin gene causative of a catatonia-depression syndrome upon aging. EMBO Mol Med (2012) 0.92
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7. J Neurosci (2011) 0.92
PD-1 regulates neural damage in oligodendroglia-induced inflammation. PLoS One (2009) 0.92
Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation. Neurobiol Dis (2013) 0.91
PLP/DM20 expression and turnover in a transgenic mouse model of Pelizaeus-Merzbacher disease. Glia (2010) 0.90
Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cereb Cortex (2011) 0.90
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy. Orphanet J Rare Dis (2014) 0.89
Adapting brain metabolism to myelination and long-range signal transduction. Glia (2014) 0.89
Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia (2013) 0.89
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A (2013) 0.88