Carlos Bustamante

Author PubWeight™ 192.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biol 2005 8.32
2 Genomic scans for selective sweeps using SNP data. Genome Res 2005 6.43
3 Equilibrium information from nonequilibrium measurements in an experimental test of Jarzynski's equality. Science 2002 5.76
4 Rapid spontaneous accessibility of nucleosomal DNA. Nat Struct Mol Biol 2004 5.00
5 Recent and ongoing selection in the human genome. Nat Rev Genet 2007 4.62
6 Direct observation of the three-state folding of a single protein molecule. Science 2005 4.48
7 Following translation by single ribosomes one codon at a time. Nature 2008 4.14
8 Structural transitions and elasticity from torque measurements on DNA. Nature 2003 3.71
9 Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. Am J Hum Genet 2010 3.69
10 RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP. Nature 2006 3.67
11 Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II. Science 2009 3.60
12 Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science 2003 3.32
13 Recent advances in optical tweezers. Annu Rev Biochem 2008 3.08
14 Intersubunit coordination in a homomeric ring ATPase. Nature 2009 2.93
15 Optical-trap force transducer that operates by direct measurement of light momentum. Methods Enzymol 2003 2.86
16 Mechanism of force generation of a viral DNA packaging motor. Cell 2005 2.81
17 Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. Nature 2007 2.64
18 Differential detection of dual traps improves the spatial resolution of optical tweezers. Proc Natl Acad Sci U S A 2006 2.48
19 Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids. PLoS Biol 2007 2.39
20 Genetic architecture of aluminum tolerance in rice (Oryza sativa) determined through genome-wide association analysis and QTL mapping. PLoS Genet 2011 2.34
21 Evolutionary history of GS3, a gene conferring grain length in rice. Genetics 2009 2.33
22 ClpX(P) generates mechanical force to unfold and translocate its protein substrates. Cell 2011 2.31
23 DNA overwinds when stretched. Nature 2006 2.27
24 DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC. Mol Cell 2006 2.25
25 Sequence-directed DNA translocation by purified FtsK. Science 2005 2.22
26 Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases. Proc Natl Acad Sci U S A 2003 2.15
27 Effect of force on mononucleosomal dynamics. Proc Natl Acad Sci U S A 2006 2.03
28 Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism. Genes Dev 2005 1.94
29 Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque. Nat Struct Mol Biol 2007 1.91
30 The effect of force on thermodynamics and kinetics of single molecule reactions. Biophys Chem 2002 1.90
31 Probing the mechanical folding kinetics of TAR RNA by hopping, force-jump, and force-ramp methods. Biophys J 2005 1.86
32 Retracted The bacterial condensin MukBEF compacts DNA into a repetitive, stable structure. Science 2004 1.83
33 Using mechanical force to probe the mechanism of pausing and arrest during continuous elongation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A 2002 1.77
34 The folding cooperativity of a protein is controlled by its chain topology. Nature 2010 1.76
35 The ribosome uses two active mechanisms to unwind messenger RNA during translation. Nature 2011 1.74
36 Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J 2008 1.74
37 Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet 2012 1.74
38 Temperature control methods in a laser tweezers system. Biophys J 2005 1.70
39 Bias and error in estimates of equilibrium free-energy differences from nonequilibrium measurements. Proc Natl Acad Sci U S A 2003 1.66
40 Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocase. Proc Natl Acad Sci U S A 2005 1.66
41 Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results. Biophys J 2007 1.61
42 Light-powering Escherichia coli with proteorhodopsin. Proc Natl Acad Sci U S A 2007 1.59
43 Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis. Nat Struct Mol Biol 2008 1.58
44 Proofreading dynamics of a processive DNA polymerase. EMBO J 2009 1.58
45 Counting single photoactivatable fluorescent molecules by photoactivated localization microscopy (PALM). Proc Natl Acad Sci U S A 2012 1.56
46 Single-molecule derivation of salt dependent base-pair free energies in DNA. Proc Natl Acad Sci U S A 2010 1.53
47 The ribosome modulates nascent protein folding. Science 2011 1.51
48 NS3 helicase actively separates RNA strands and senses sequence barriers ahead of the opening fork. Proc Natl Acad Sci U S A 2007 1.50
49 Identification of the FtsK sequence-recognition domain. Nat Struct Mol Biol 2006 1.49
50 Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method. Proc Natl Acad Sci U S A 2007 1.49
51 Three-dimensional architecture of the bacteriophage phi29 packaged genome and elucidation of its packaging process. Virology 2007 1.48
52 Nucleosomal elements that control the topography of the barrier to transcription. Cell 2012 1.46
53 Substrate interactions and promiscuity in a viral DNA packaging motor. Nature 2009 1.41
54 High degree of coordination and division of labor among subunits in a homomeric ring ATPase. Cell 2012 1.35
55 SpoIIIE strips proteins off the DNA during chromosome translocation. Genes Dev 2008 1.31
56 Single-base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase. Science 2011 1.31
57 Thermal probing of E. coli RNA polymerase off-pathway mechanisms. J Mol Biol 2008 1.29
58 Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers. Eur Biophys J 2008 1.29
59 Mechanochemistry of a viral DNA packaging motor. J Mol Biol 2010 1.29
60 Unusual mechanical stability of a minimal RNA kissing complex. Proc Natl Acad Sci U S A 2006 1.29
61 Relating single-molecule measurements to thermodynamics. Biophys J 2003 1.26
62 Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of -1 ribosomal frameshifting. Proc Natl Acad Sci U S A 2009 1.25
63 Characterization of the mechanical unfolding of RNA pseudoknots. J Mol Biol 2007 1.20
64 Mechanics and structure of titin oligomers explored with atomic force microscopy. Biochim Biophys Acta 2003 1.19
65 The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes. Nat Struct Mol Biol 2011 1.19
66 Real-time control of the energy landscape by force directs the folding of RNA molecules. Proc Natl Acad Sci U S A 2007 1.15
67 Effect of protein structure on mitochondrial import. Proc Natl Acad Sci U S A 2005 1.15
68 Determination of thermodynamics and kinetics of RNA reactions by force. Q Rev Biophys 2006 1.13
69 Tension induces a base-paired overstretched DNA conformation. Proc Natl Acad Sci U S A 2012 1.13
70 The molten globule state is unusually deformable under mechanical force. Proc Natl Acad Sci U S A 2012 1.07
71 Randomized trial of personal genomics for preventive cardiology: design and challenges. Circ Cardiovasc Genet 2012 1.06
72 Differential force microscope for long time-scale biophysical measurements. Rev Sci Instrum 2007 1.06
73 Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases. Proc Natl Acad Sci U S A 2012 1.06
74 Direct observation of a force-induced switch in the anisotropic mechanical unfolding pathway of a protein. Proc Natl Acad Sci U S A 2012 1.05
75 Measurement of the effect of monovalent cations on RNA hairpin stability. J Am Chem Soc 2007 1.05
76 Exact solutions for kinetic models of macromolecular dynamics. J Phys Chem B 2008 1.04
77 Dynamic SpoIIIE assembly mediates septal membrane fission during Bacillus subtilis sporulation. Genes Dev 2010 1.04
78 Ribosomal protein S1 unwinds double-stranded RNA in multiple steps. Proc Natl Acad Sci U S A 2012 1.04
79 Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations. BMC Genet 2012 1.01
80 A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation. Proc Natl Acad Sci U S A 2014 1.00
81 Finding a protein's Achilles heel. Nat Struct Biol 2003 0.99
82 Visualizing RNA extrusion and DNA wrapping in transcription elongation complexes of bacterial and eukaryotic RNA polymerases. J Mol Biol 2003 0.98
83 Molecular mechanisms of transcription through single-molecule experiments. Chem Rev 2014 0.98
84 Methods in statistical kinetics. Methods Enzymol 2010 0.97
85 Bayesian estimates of free energies from nonequilibrium work data in the presence of instrument noise. J Chem Phys 2008 0.96
86 Single molecule transcription elongation. Methods 2009 0.94
87 Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics. Proc Natl Acad Sci U S A 2014 0.89
88 Peptide nucleic acids as tools for single-molecule sequence detection and manipulation. Nano Lett 2010 0.88
89 Mechanistic constraints from the substrate concentration dependence of enzymatic fluctuations. Proc Natl Acad Sci U S A 2010 0.88
90 Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. J Mol Biol 2004 0.88
91 Guanosine triphosphate acts as a cofactor to promote assembly of initial P-element transposase-DNA synaptic complexes. Genes Dev 2005 0.88
92 Analysis of P element transposase protein-DNA interactions during the early stages of transposition. J Biol Chem 2007 0.87
93 DNA molecular handles for single-molecule protein-folding studies by optical tweezers. Methods Mol Biol 2011 0.86
94 Suicidal ideation among students enrolled in healthcare training programs: a cross-sectional study. Rev Bras Psiquiatr 2009 0.82
95 Extracting signal from noise: kinetic mechanisms from a Michaelis-Menten-like expression for enzymatic fluctuations. FEBS J 2013 0.81
96 High-resolution dual-trap optical tweezers with differential detection: alignment of instrument components. Cold Spring Harb Protoc 2009 0.81
97 Introduction to single molecule imaging and mechanics: seeing and touching molecules one at a time. Chem Rev 2014 0.81
98 High-resolution dual-trap optical tweezers with differential detection: instrument design. Cold Spring Harb Protoc 2009 0.81
99 Solvent inhalation (toluene and n-hexane) during the brain growth spurt impairs the maturation of frontal, parietal and occipital cerebrocortical neurons in rats. Int J Dev Neurosci 2010 0.80
100 High-resolution dual-trap optical tweezers with differential detection: an introduction. Cold Spring Harb Protoc 2009 0.80
101 Sequence-dependent upstream DNA-RNA polymerase interactions in the open complex with lambdaPR and lambdaPRM promoters and implications for the mechanism of promoter interference. J Mol Biol 2008 0.80
102 Maternal stress induces long-lasting Purkinje cell developmental impairments in mouse offspring. Eur J Pediatr 2010 0.80
103 Coupling translocation with nucleic acid unwinding by NS3 helicase. J Mol Biol 2010 0.79
104 Melatonin ameliorates neocortical neuronal dendritic impairment induced by toluene inhalation in the rat. Exp Toxicol Pathol 2010 0.78
105 Structural neuroplasticity induced by melatonin in entorhinal neurons of rats exposed to toluene inhalation. Acta Neurobiol Exp (Wars) 2011 0.78
106 Single course of antenatal betamethasone produces delayed changes in morphology and calbindin-D28k expression in a rat's cerebellar Purkinje cells. Acta Neurobiol Exp (Wars) 2014 0.78
107 Prenatal stress alters the behavior and dendritic morphology of the medial orbitofrontal cortex in mouse offspring during lactation. Int J Dev Neurosci 2013 0.78
108 Early postweaning social isolation but not environmental enrichment modifies vermal Purkinje cell dendritic outgrowth in rats. Acta Neurobiol Exp (Wars) 2013 0.77
109 Melatonin promotes distal dendritic ramifications in layer II/III cortical pyramidal cells of rats exposed to toluene vapors. Brain Res 2010 0.76
110 A genome-wide linkage scan in German shepherd dogs localizes canine platelet procoagulant deficiency (Scott syndrome) to canine chromosome 27. Gene 2010 0.76
111 Molecular handles for the mechanical manipulation of single-membrane proteins in living cells. IEEE Trans Nanobioscience 2005 0.76
112 Single molecule conformational memory extraction: p5ab RNA hairpin. J Phys Chem B 2014 0.75
113 Selegiline (deprenyl) decreases calbindin-D28k expression in cortical neurons of rats socially deprived during the post-weaning period. Int J Dev Neurosci 2012 0.75
114 High-resolution dual-trap optical tweezers with differential detection: managing environmental noise. Cold Spring Harb Protoc 2009 0.75
115 Retraction. Science 2005 0.75
116 High-resolution dual-trap optical tweezers with differential detection: minimizing the influence of measurement noise. Cold Spring Harb Protoc 2009 0.75
117 Unraveling the Thousand Word Picture: An Introduction to Super-Resolution Data Analysis. Chem Rev 2017 0.75
118 Gastroprotective activity of solidagenone on experimentally-induced gastric lesions in rats. J Pharm Pharmacol 2002 0.75
119 High-resolution dual-trap optical tweezers with differential detection: data collection and instrument calibration. Cold Spring Harb Protoc 2009 0.75