Published in Mol Cell on November 17, 2006
Chromatin remodeling: insights and intrigue from single-molecule studies. Nat Struct Mol Biol (2007) 2.79
Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription. Cell (2008) 2.47
Single-molecule biophysics: at the interface of biology, physics and chemistry. J R Soc Interface (2008) 2.06
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Dynamics of nucleosome remodelling by individual ACF complexes. Nature (2009) 1.68
Structure of a RSC-nucleosome complex and insights into chromatin remodeling. Nat Struct Mol Biol (2008) 1.62
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Chromatin and transcription in yeast. Genetics (2012) 1.61
Architecture of the SWI/SNF-nucleosome complex. Mol Cell Biol (2008) 1.58
Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method. Proc Natl Acad Sci U S A (2007) 1.49
Nucleosomal elements that control the topography of the barrier to transcription. Cell (2012) 1.46
A DNA-translocating Snf2 molecular motor: Saccharomyces cerevisiae Rdh54 displays processive translocation and extrudes DNA loops. J Mol Biol (2007) 1.41
Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes. EMBO J (2009) 1.40
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ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell (2013) 1.29
Conformational changes associated with template commitment in ATP-dependent chromatin remodeling by ISW2. Mol Cell (2009) 1.29
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Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I. EMBO J (2008) 1.28
The RSC chromatin remodelling ATPase translocates DNA with high force and small step size. EMBO J (2011) 1.24
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Mechanisms of ATP-dependent nucleosome sliding. Curr Opin Struct Biol (2010) 1.23
Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell (2009) 1.21
The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes. Nat Struct Mol Biol (2011) 1.19
Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer. Proc Natl Acad Sci U S A (2010) 1.16
Epigenetic regulatory mechanisms in vertebrate eye development and disease. Heredity (Edinb) (2010) 1.16
Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling. Nucleic Acids Res (2011) 1.15
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc Natl Acad Sci U S A (2010) 1.15
Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism. Elife (2013) 1.14
Diversity of operation in ATP-dependent chromatin remodelers. Biochim Biophys Acta (2011) 1.14
The ATPase domain of ISWI is an autonomous nucleosome remodeling machine. Nat Struct Mol Biol (2012) 1.13
The helicase-like domains of type III restriction enzymes trigger long-range diffusion along DNA. Science (2013) 1.09
The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes. EMBO J (2011) 1.09
Large-scale functional organization of long-range chromatin interaction networks. Cell Rep (2012) 1.08
Nucleosome sliding mechanisms: new twists in a looped history. Nat Struct Mol Biol (2013) 1.07
Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF. Nucleic Acids Res (2009) 1.07
Mutations to the histone H3 alpha N region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions. Nucleic Acids Res (2009) 1.06
Chromatin dynamics during repair of chromosomal DNA double-strand breaks. Epigenomics (2009) 1.05
Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA. Biochemistry (2007) 1.04
Mechanism(s) of SWI/SNF-induced nucleosome mobilization. Chembiochem (2010) 1.04
Multiple aspects of ATP-dependent nucleosome translocation by RSC and Mi-2 are directed by the underlying DNA sequence. PLoS One (2009) 1.04
Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines. Curr Opin Struct Biol (2012) 1.04
Chromatin fiber dynamics under tension and torsion. Int J Mol Sci (2010) 1.03
The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling. Nucleic Acids Res (2010) 1.02
Atomic force microscopy imaging of SWI/SNF action: mapping the nucleosome remodeling and sliding. Biophys J (2007) 1.01
Recent advances in single molecule studies of nucleosomes. Curr Opin Struct Biol (2011) 0.99
A proposal for kinetic proof reading by ISWI family chromatin remodeling motors. Curr Opin Chem Biol (2010) 0.97
The DNA sequence-dependence of nucleosome positioning in vivo and in vitro. J Biomol Struct Dyn (2010) 0.96
Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine. Nucleic Acids Res (2008) 0.95
The MLE subunit of the Drosophila MSL complex uses its ATPase activity for dosage compensation and its helicase activity for targeting. Mol Cell Biol (2007) 0.95
Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription. Prog Biophys Mol Biol (2010) 0.95
Dynamic regulation of transcription factors by nucleosome remodeling. Elife (2015) 0.94
The importance of surfaces in single-molecule bioscience. Mol Biosyst (2008) 0.94
One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes? Biochim Biophys Acta (2011) 0.93
Role of nucleosome remodeling in neurodevelopmental and intellectual disability disorders. Front Behav Neurosci (2015) 0.93
Kinetic mechanism for single-stranded DNA binding and translocation by Saccharomyces cerevisiae Isw2. Biochemistry (2009) 0.92
Kinetics and thermodynamics of phenotype: unwinding and rewinding the nucleosome. J Mol Biol (2012) 0.90
Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle. PLoS Genet (2014) 0.89
Superfamily 2 helicases. Front Biosci (Landmark Ed) (2012) 0.89
Two-step mechanism for modifier of transcription 1 (Mot1) enzyme-catalyzed displacement of TATA-binding protein (TBP) from DNA. J Biol Chem (2012) 0.89
Nucleic acid binding activity of human Cockayne syndrome B protein and identification of Ca(2+) as a novel metal cofactor. J Mol Biol (2009) 0.89
The BAF60 subunit of the SWI/SNF chromatin-remodeling complex directly controls the formation of a gene loop at FLOWERING LOCUS C in Arabidopsis. Plant Cell (2014) 0.89
ABF1-binding sites promote efficient global genome nucleotide excision repair. J Biol Chem (2008) 0.88
In vivo role for the chromatin-remodeling enzyme SWI/SNF in the removal of promoter nucleosomes by disassembly rather than sliding. J Biol Chem (2011) 0.86
Distinct contributions of MSL complex subunits to the transcriptional enhancement responsible for dosage compensation in Drosophila. Nucleic Acids Res (2012) 0.86
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nat Rev Mol Cell Biol (2017) 0.84
The SnAC domain of SWI/SNF is a histone anchor required for remodeling. Mol Cell Biol (2012) 0.83
Structural dynamics of nucleosomes at single-molecule resolution. Trends Biochem Sci (2012) 0.83
Stepwise nucleosome translocation by RSC remodeling complexes. Elife (2016) 0.83
SWI/SNF- and RSC-catalyzed nucleosome mobilization requires internal DNA loop translocation within nucleosomes. Mol Cell Biol (2011) 0.82
Combined versatile high-resolution optical tweezers and single-molecule fluorescence microscopy. Rev Sci Instrum (2012) 0.82
Structure and dynamics of DNA loops on nucleosomes studied with atomistic, microsecond-scale molecular dynamics. Nucleic Acids Res (2016) 0.81
Quantifying transient binding of ISWI chromatin remodelers in living cells by pixel-wise photobleaching profile evolution analysis. Proc Natl Acad Sci U S A (2012) 0.81
Recent insights from in vitro single-molecule studies into nucleosome structure and dynamics. Biophys Rev (2016) 0.80
Allosteric interactions of DNA and nucleotides with S. cerevisiae RSC. Biochemistry (2011) 0.80
ATP-dependent looping of DNA by ISWI. J Biophotonics (2008) 0.80
High-resolution optical tweezers for single-molecule manipulation. Yale J Biol Med (2013) 0.80
ISWI remodels nucleosomes through a random walk. Biochemistry (2014) 0.79
ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA. PLoS One (2012) 0.79
Chromatin remodelling complex RSC promotes base excision repair in chromatin of Saccharomyces cerevisiae. DNA Repair (Amst) (2014) 0.78
Quantitative determination of binding of ISWI to nucleosomes and DNA shows allosteric regulation of DNA binding by nucleotides. Biochemistry (2014) 0.77
Monitoring conformational dynamics with single-molecule fluorescence energy transfer: applications in nucleosome remodeling. Methods Enzymol (2012) 0.76
Routes to DNA accessibility: alternative pathways for nucleosome unwinding. Biophys J (2014) 0.76
Kinetic mechanism of DNA translocation by the RSC molecular motor. Arch Biochem Biophys (2013) 0.76
High mobility group protein 1: A collaborator in nucleosome dynamics and estrogen-responsive gene expression. World J Biol Chem (2016) 0.75
Transcription-induced DNA supercoiling: New roles of intranucleosomal DNA loops in DNA repair and transcription. Transcription (2016) 0.75
Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes. Elife (2017) 0.75
Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development. Cytokine (2010) 0.75
Extra views on Structure and dynamics of DNA loops on nucleosomes studied with molecular simulations. Nucleus (2016) 0.75
Making Time: Conservation of Biological Clocks from Fungi to Animals. Microbiol Spectr (2017) 0.75
Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science (2006) 11.20
The biology of chromatin remodeling complexes. Annu Rev Biochem (2009) 10.02
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature (2006) 9.30
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell (2008) 8.62
A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biol (2005) 8.32
Ten years of tension: single-molecule DNA mechanics. Nature (2003) 7.20
Genomic scans for selective sweeps using SNP data. Genome Res (2005) 6.43
Distinctive chromatin in human sperm packages genes for embryo development. Nature (2009) 6.18
Equilibrium information from nonequilibrium measurements in an experimental test of Jarzynski's equality. Science (2002) 5.76
Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell (2005) 5.36
Rapid spontaneous accessibility of nucleosomal DNA. Nat Struct Mol Biol (2004) 5.00
The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome. PLoS Genet (2008) 4.91
Recent and ongoing selection in the human genome. Nat Rev Genet (2007) 4.62
Direct observation of the three-state folding of a single protein molecule. Science (2005) 4.48
Following translation by single ribosomes one codon at a time. Nature (2008) 4.14
Dynamic transcriptome of Schizosaccharomyces pombe shown by RNA-DNA hybrid mapping. Nat Genet (2008) 4.03
A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS One (2009) 3.83
Chromatin remodelling: the industrial revolution of DNA around histones. Nat Rev Mol Cell Biol (2006) 3.79
Structural transitions and elasticity from torque measurements on DNA. Nature (2003) 3.71
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. Am J Hum Genet (2010) 3.69
RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP. Nature (2006) 3.67
Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II. Science (2009) 3.60
Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA. Proc Natl Acad Sci U S A (2002) 3.52
Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes. Mol Cell (2007) 3.38
Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science (2003) 3.32
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell (2005) 3.24
Recent advances in optical tweezers. Annu Rev Biochem (2008) 3.08
Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev (2002) 2.97
Intersubunit coordination in a homomeric ring ATPase. Nature (2009) 2.93
Optical-trap force transducer that operates by direct measurement of light momentum. Methods Enzymol (2003) 2.86
Mechanism of force generation of a viral DNA packaging motor. Cell (2005) 2.81
Chromatin remodeling through directional DNA translocation from an internal nucleosomal site. Nat Struct Mol Biol (2005) 2.81
Molecular biology. Chromatin higher order folding--wrapping up transcription. Science (2002) 2.71
Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators. Curr Biol (2006) 2.67
A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme. Science (2013) 2.67
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. Nature (2007) 2.64
The SANT domain: a unique histone-tail-binding module? Nat Rev Mol Cell Biol (2004) 2.63
The RNA polymerase III transcriptome revealed by genome-wide localization and activity-occupancy relationships. Proc Natl Acad Sci U S A (2003) 2.61
Differential detection of dual traps improves the spatial resolution of optical tweezers. Proc Natl Acad Sci U S A (2006) 2.48
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes Dev (2005) 2.47
Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science (2003) 2.46
Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14. EMBO J (2004) 2.46
Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates. Cell (2009) 2.40
Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids. PLoS Biol (2007) 2.39
Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows. Nature (2010) 2.39
Genetic architecture of aluminum tolerance in rice (Oryza sativa) determined through genome-wide association analysis and QTL mapping. PLoS Genet (2011) 2.34
Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels. Fertil Steril (2013) 2.33
Evolutionary history of GS3, a gene conferring grain length in rice. Genetics (2009) 2.33
Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol Cell (2002) 2.33
ClpX(P) generates mechanical force to unfold and translocate its protein substrates. Cell (2011) 2.31
Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nat Struct Mol Biol (2010) 2.30
The Ino80 chromatin-remodeling enzyme regulates replisome function and stability. Nat Struct Mol Biol (2008) 2.30
DNA overwinds when stretched. Nature (2006) 2.27
Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity. Cell (2011) 2.26
The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases. Nat Struct Mol Biol (2008) 2.26
Sequence-directed DNA translocation by purified FtsK. Science (2005) 2.22
Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol Cell (2003) 2.17
Rad54p is a chromatin remodeling enzyme required for heteroduplex DNA joint formation with chromatin. J Biol Chem (2003) 2.15
Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases. Proc Natl Acad Sci U S A (2003) 2.15
Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev (2009) 2.13
The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Mol Cell (2002) 2.10
Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes Dev (2006) 2.05
Effect of force on mononucleosomal dynamics. Proc Natl Acad Sci U S A (2006) 2.03
ATP-dependent chromatin remodeling. Curr Top Dev Biol (2005) 2.02
Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern. Cell (2013) 1.95
Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Res (2011) 1.94
Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism. Genes Dev (2005) 1.94
RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes. EMBO J (2007) 1.93
Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region. Mol Cell (2002) 1.91
Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque. Nat Struct Mol Biol (2007) 1.91
The effect of force on thermodynamics and kinetics of single molecule reactions. Biophys Chem (2002) 1.90
Forces driving epithelial spreading in zebrafish gastrulation. Science (2012) 1.89
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell (2010) 1.89
Polarization of PAR proteins by advective triggering of a pattern-forming system. Science (2011) 1.88
A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation. Genes Dev (2005) 1.87
Probing the mechanical folding kinetics of TAR RNA by hopping, force-jump, and force-ramp methods. Biophys J (2005) 1.86
Structural analysis of the yeast SWI/SNF chromatin remodeling complex. Nat Struct Biol (2003) 1.86
Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol Cell (2007) 1.85
Retracted The bacterial condensin MukBEF compacts DNA into a repetitive, stable structure. Science (2004) 1.83
The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (2009) 1.83
The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Mol Cell Biol (2004) 1.80
Using mechanical force to probe the mechanism of pausing and arrest during continuous elongation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A (2002) 1.77
The folding cooperativity of a protein is controlled by its chain topology. Nature (2010) 1.76
The ribosome uses two active mechanisms to unwind messenger RNA during translation. Nature (2011) 1.74
Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression. Mol Cell (2006) 1.74
Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J (2008) 1.74
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet (2012) 1.74
Chromatin and the genome integrity network. Nat Rev Genet (2013) 1.72
Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes. Nat Struct Biol (2002) 1.71
Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development. Mol Cell Biol (2006) 1.71