PubRank

Burkhard Tümmler

Author PubWeight™ 112.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med 2008 3.41
2 Population structure of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 2007 2.56
3 Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infection. Infect Immun 2005 2.51
4 Highly adherent small-colony variants of Pseudomonas aeruginosa in cystic fibrosis lung infection. J Med Microbiol 2003 2.17
5 Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone. J Bacteriol 2002 2.14
6 Quorum sensing: the power of cooperation in the world of Pseudomonas. Environ Microbiol 2005 2.12
7 Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence. Am J Respir Crit Care Med 2009 2.08
8 Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa C. J Bacteriol 2004 2.04
9 The neglected intrinsic resistome of bacterial pathogens. PLoS One 2008 1.82
10 A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J Bacteriol 2005 1.74
11 Genome diversity of Pseudomonas aeruginosa PAO1 laboratory strains. J Bacteriol 2009 1.73
12 Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. Hum Mutat 2009 1.71
13 Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs. Environ Microbiol 2011 1.70
14 Intestinal current measurement for diagnostic classification of patients with questionable cystic fibrosis: validation and reference data. Thorax 2010 1.61
15 Pseudomonas aeruginosa Genomic Structure and Diversity. Front Microbiol 2011 1.43
16 Diversity of the abundant pKLC102/PAGI-2 family of genomic islands in Pseudomonas aeruginosa. J Bacteriol 2006 1.43
17 Expression analysis of a highly adherent and cytotoxic small colony variant of Pseudomonas aeruginosa isolated from a lung of a patient with cystic fibrosis. J Bacteriol 2004 1.43
18 The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases. Proc Natl Acad Sci U S A 2006 1.39
19 Global features of the Pseudomonas putida KT2440 genome sequence. Environ Microbiol 2002 1.39
20 Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage patterns. BMC Bioinformatics 2004 1.34
21 Global regulation of quorum sensing and virulence by VqsR in Pseudomonas aeruginosa. Microbiology 2004 1.32
22 Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia. J Med Genet 2010 1.26
23 Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping. J Bacteriol 2004 1.24
24 Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Microbiology 2006 1.20
25 Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis. Microbiology 2007 1.20
26 Pseudomonas aeruginosa and Burkholderia cepacia in cystic fibrosis: genome evolution, interactions and adaptation. Int J Med Microbiol 2004 1.18
27 Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence. PLoS Pathog 2009 1.15
28 The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. Hum Genet 2004 1.14
29 The genome structure of Pseudomonas putida: high-resolution mapping and microarray analysis. Environ Microbiol 2002 1.13
30 Think big--giant genes in bacteria. Environ Microbiol 2008 1.13
31 Origins of cystic fibrosis lung disease. N Engl J Med 2015 1.12
32 Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol 2005 1.10
33 Functional genomics of stress response in Pseudomonas putida KT2440. J Bacteriol 2006 1.09
34 Differentiation of regions with atypical oligonucleotide composition in bacterial genomes. BMC Bioinformatics 2005 1.08
35 Inter- and intraclonal diversity of the Pseudomonas aeruginosa proteome manifests within the secretome. J Bacteriol 2003 1.07
36 Characterization of poxB, a chromosomal-encoded Pseudomonas aeruginosa oxacillinase. Gene 2005 1.06
37 Genes in the vicinity of CFTR modulate the cystic fibrosis phenotype in highly concordant or discordant F508del homozygous sib pairs. Hum Genet 2002 1.05
38 Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers. J Cyst Fibros 2004 1.05
39 The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. Hum Genet 2006 1.05
40 Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment. Environ Microbiol 2014 1.04
41 Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis. Int J Med Microbiol 2010 1.04
42 Genometa--a fast and accurate classifier for short metagenomic shotgun reads. PLoS One 2012 1.02
43 Basic protocol for transepithelial nasal potential difference measurements. J Cyst Fibros 2004 1.01
44 Pseudomonas aeruginosa population biology in chronic obstructive pulmonary disease. J Infect Dis 2009 1.01
45 Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection. PLoS One 2008 0.99
46 Genome Sequence of Burkholderia cenocepacia H111, a Cystic Fibrosis Airway Isolate. Genome Announc 2014 0.98
47 GeneChip expression analysis of the VqsR regulon of Pseudomonas aeruginosa TB. FEMS Microbiol Lett 2005 0.98
48 Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection. Mol Microbiol 2008 0.97
49 Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis. PLoS One 2012 0.97
50 Intraclonal diversity of the Pseudomonas aeruginosa cystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence. Environ Microbiol 2012 0.97
51 Antibiotic treatment of CF lung disease: from bench to bedside. J Cyst Fibros 2011 0.96
52 Crystal structure of the electron transfer complex rubredoxin rubredoxin reductase of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 2007 0.95
53 Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death. Biochem Biophys Res Commun 2010 0.94
54 EuroCareCF quality assessment of diagnostic microbiology of cystic fibrosis isolates. J Clin Microbiol 2009 0.93
55 The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes through oligonucleotide usage. BMC Bioinformatics 2008 0.93
56 Functional analysis of F508del CFTR in native human colon. Biochim Biophys Acta 2010 0.92
57 A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci. PLoS One 2012 0.92
58 In silico comparison of pKLC102-like genomic islands of Pseudomonas aeruginosa. FEMS Microbiol Lett 2007 0.91
59 Murine pulmonary infection with Listeria monocytogenes: differential susceptibility of BALB/c, C57BL/6 and DBA/2 mice. Microbes Infect 2005 0.91
60 Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73. Genome Announc 2013 0.91
61 Developing an international Pseudomonas aeruginosa reference panel. Microbiologyopen 2013 0.91
62 In-vivo expression profiling of Pseudomonas aeruginosa infections reveals niche-specific and strain-independent transcriptional programs. PLoS One 2011 0.89
63 Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray transcriptomics. Environ Microbiol 2011 0.89
64 Spontaneous rescue from cystic fibrosis in a mouse model. BMC Genet 2006 0.87
65 Functional genomics of Pseudomonas aeruginosa to identify habitat-specific determinants of pathogenicity. Int J Med Microbiol 2007 0.86
66 Intraclonal genome diversity of Pseudomonas aeruginosa clones CHA and TB. BMC Genomics 2013 0.86
67 Advances in computational analysis of metagenome sequences. Environ Microbiol 2012 0.84
68 Comparative genomics of green sulfur bacteria. Photosynth Res 2010 0.83
69 An association study on contrasting cystic fibrosis endophenotypes recognizes KRT8 but not KRT18 as a modifier of cystic fibrosis disease severity and CFTR mediated residual chloride secretion. BMC Med Genet 2011 0.83
70 An intragenic deletion in pilQ leads to nonpiliation of a Pseudomonas aeruginosa strain isolated from cystic fibrosis lung. FEMS Microbiol Lett 2007 0.83
71 Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6. Hum Genet 2010 0.83
72 The extensive set of accessory Pseudomonas aeruginosa genomic components. FEMS Microbiol Lett 2014 0.83
73 Lung function and inflammation during murine Pseudomonas aeruginosa airway infection. Immunobiology 2011 0.83
74 Role of CD95 in pulmonary inflammation and infection in cystic fibrosis. J Mol Med (Berl) 2012 0.82
75 Instability of the insertional mutation in CftrTgH(neoim)Hgu cystic fibrosis mouse model. BMC Genet 2004 0.82
76 Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent. Respir Res 2011 0.82
77 Beneficial effects of TLR-2/6 ligation in pulmonary bacterial infection and immunization with Pseudomonas aeruginosa. Inflammation 2010 0.82
78 Visualization of Pseudomonas genomic structure by abundant 8-14mer oligonucleotides. Environ Microbiol 2009 0.81
79 Transmission ratio distortion and maternal effects confound the analysis of modulators of cystic fibrosis disease severity on 19q13. Eur J Hum Genet 2007 0.81
80 Transcript profiling of the Pseudomonas aeruginosa genomic islands PAGI-2 and pKLC102. Microbiology 2008 0.81
81 Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation. Eur J Hum Genet 2011 0.81
82 Global features of the Alcanivorax borkumensis SK2 genome. Environ Microbiol 2007 0.81
83 Feasibility and variability of measuring the Lung Clearance Index in a multi-center setting. Pediatr Pulmonol 2011 0.81
84 Proteome analysis of intraclonal diversity of two Pseudomonas aeruginosa TB clone isolates. Proteomics 2004 0.80
85 Effective prevention of Pseudomonas aeruginosa cross-infection at a cystic fibrosis centre - results of a 10-year prospective study. Int J Med Microbiol 2011 0.80
86 Genetic modifiers in cystic fibrosis. N Engl J Med 2006 0.80
87 Functional genomics of the initial phase of cold adaptation of Pseudomonas putida KT2440. FEMS Microbiol Lett 2011 0.79
88 Abundant oligonucleotides common to most bacteria. PLoS One 2010 0.79
89 Assessing Pseudomonas virulence using mammalian models: acute infection model. Methods Mol Biol 2014 0.79
90 In vivo imaging of bioluminescent Pseudomonas aeruginosa in an acute murine airway infection model. Pathog Dis 2014 0.79
91 Evidence for polyadenylated mRNA in Pseudomonas aeruginosa. J Bacteriol 2004 0.79
92 CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine. Eur J Hum Genet 2012 0.79
93 Head-out spirometry accurately monitors the course of Pseudomonas aeruginosa lung infection in mice. Respiration 2010 0.79
94 Clinical and molecular characterization of the potential CF disease modifier syntaxin 1A. Eur J Hum Genet 2013 0.78
95 Very mild disease phenotype of congenic CftrTgH(neoim)Hgu cystic fibrosis mice. BMC Genet 2008 0.78
96 Ex vivo biochemical analysis of CFTR in human rectal biopsies. Biochim Biophys Acta 2006 0.78
97 Differential decay of parent-of-origin-specific genomic sharing in cystic fibrosis-affected sib pairs maps a paternally imprinted locus to 7q34. Eur J Hum Genet 2010 0.78
98 Frequency of the hyperactive W493R ENaC variant in carriers of a CFTR mutation. J Cyst Fibros 2011 0.76
99 Cystic fibrosis and NOS3. Am J Respir Crit Care Med 2004 0.76
100 Genes, environment, ion transport, and cystic fibrosis. Am J Respir Crit Care Med 2004 0.75
101 Intestinal current measurements to diagnose cystic fibrosis. J Cyst Fibros 2004 0.75
102 Cystic fibrosis disease-specific centiles in 2000 and 2005. Am J Respir Crit Care Med 2006 0.75
103 Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cell Physiol Biochem 2015 0.75
104 CFTR protein analysis of splice site mutation 2789+5 G-A. J Cyst Fibros 2007 0.75
105 In-vivo and ex-vivo functional assessment. J Cyst Fibros 2004 0.75
106 Immunochemical analysis of mutant CFTR in lung explants. Cell Physiol Biochem 2012 0.75