Published in PLoS Genet on November 13, 2006
Evolutionary breakpoints in the gibbon suggest association between cytosine methylation and karyotype evolution. PLoS Genet (2009) 2.07
The origins and impact of primate segmental duplications. Trends Genet (2009) 1.69
Gibbon genome and the fast karyotype evolution of small apes. Nature (2014) 1.43
Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution. BMC Evol Biol (2009) 1.40
Tracking the complex flow of chromosome rearrangements from the Hominoidea Ancestor to extant Hylobates and Nomascus Gibbons by high-resolution synteny mapping. Genome Res (2008) 1.29
Molecular mechanisms of chromosomal rearrangement during primate evolution. Chromosome Res (2008) 1.22
Sequencing human-gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites. Genome Res (2008) 1.21
New insights into centromere organization and evolution from the white-cheeked gibbon and marmoset. Mol Biol Evol (2009) 1.10
Molecular cytogenetic and genomic insights into chromosomal evolution. Heredity (Edinb) (2011) 1.01
Patterns of genetic variation within and between Gibbon species. Mol Biol Evol (2011) 0.99
Decoding plant and animal genome plasticity from differential paleo-evolutionary patterns and processes. Genome Biol Evol (2012) 0.92
A most distant intergeneric hybrid offspring (Larcon) of lesser apes, Nomascus leucogenys and Hylobates lar. Hum Genet (2007) 0.88
A comprehensive molecular cytogenetic analysis of chromosome rearrangements in gibbons. Genome Res (2012) 0.88
A chromosomal inversion unique to the northern white-cheeked gibbon. PLoS One (2009) 0.87
Assessing the role of tandem repeats in shaping the genomic architecture of great apes. PLoS One (2011) 0.79
The mysteries of chromosome evolution in gibbons: methylation is a prime suspect. PLoS Genet (2009) 0.78
Structural Variant Detection by Large-scale Sequencing Reveals New Evolutionary Evidence on Breed Divergence between Chinese and European Pigs. Sci Rep (2016) 0.75
A quick and robust MHC typing method for free-ranging and captive primate species. Immunogenetics (2017) 0.75
BLAT--the BLAST-like alignment tool. Genome Res (2002) 126.78
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature (2005) 23.04
Recent segmental duplications in the human genome. Science (2002) 21.30
A physical map of the human genome. Nature (2001) 12.39
Segmental duplications: organization and impact within the current human genome project assembly. Genome Res (2001) 11.77
Degenerate oligonucleotide-primed PCR: general amplification of target DNA by a single degenerate primer. Genomics (1992) 9.06
End-sequence profiling: sequence-based analysis of aberrant genomes. Proc Natl Acad Sci U S A (2003) 7.70
A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet (2004) 7.68
Multicolor spectral karyotyping of human chromosomes. Science (1996) 7.65
BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol (2002) 6.35
Lengths of chromosomal segments conserved since divergence of man and mouse. Proc Natl Acad Sci U S A (1984) 6.26
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science (2005) 5.47
Bacterial artificial chromosome libraries for mouse sequencing and functional analysis. Genome Res (2000) 5.13
A physical map of the mouse genome. Nature (2002) 4.97
High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparative genomic hybridization. Am J Hum Genet (2002) 3.10
Hotspots of mammalian chromosomal evolution. Genome Biol (2004) 2.92
A genome-wide survey of structural variation between human and chimpanzee. Genome Res (2005) 2.61
Enrichment of segmental duplications in regions of breaks of synteny between the human and mouse genomes suggest their involvement in evolutionary rearrangements. Hum Mol Genet (2003) 2.07
A set of BAC clones spanning the human genome. Nucleic Acids Res (2004) 2.00
Chromosome evolution in eukaryotes: a multi-kingdom perspective. Trends Genet (2005) 1.93
Reconstruction of genomic rearrangements in great apes and gibbons by chromosome painting. Proc Natl Acad Sci U S A (1992) 1.88
Gross chromosome rearrangements mediated by transposable elements in Drosophila melanogaster. Bioessays (1994) 1.82
Chromosomal phylogeny and evolution of gibbons (Hylobatidae). Hum Genet (2003) 1.79
A palindrome-mediated mechanism distinguishes translocations involving LCR-B of chromosome 22q11.2. Hum Mol Genet (2003) 1.67
Refinement of a chimpanzee pericentric inversion breakpoint to a segmental duplication cluster. Genome Biol (2003) 1.65
The evolutionary chromosome translocation 4;19 in Gorilla gorilla is associated with microduplication of the chromosome fragment syntenic to sequences surrounding the human proximal CMT1A-REP. Genome Res (2001) 1.64
Human, mouse, and rat genome large-scale rearrangements: stability versus speciation. Genome Res (2004) 1.63
Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines. Proc Natl Acad Sci U S A (1990) 1.52
The evolution of eutherian chromosomes. Curr Opin Genet Dev (2004) 1.51
Neocentromeres in 15q24-26 map to duplicons which flanked an ancestral centromere in 15q25. Genome Res (2003) 1.44
The foldback-like transposon Galileo is involved in the generation of two different natural chromosomal inversions of Drosophila buzzatii. Mol Biol Evol (2003) 1.36
Genomic reorganization in the concolor gibbon (Hylobates concolor) revealed by chromosome painting. Genomics (1995) 1.28
Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17. Am J Hum Genet (2002) 1.19
Breakpoint analysis of the pericentric inversion between chimpanzee chromosome 10 and the homologous chromosome 12 in humans. Cytogenet Genome Res (2005) 1.18
Chromosome 6 phylogeny in primates and centromere repositioning. Mol Biol Evol (2003) 1.13
Detailed Hylobates lar karyotype defined by 25-color FISH and multicolor banding. Int J Mol Med (2003) 1.12
Genomic reorganization and disrupted chromosomal synteny in the siamang (Hylobates syndactylus) revealed by fluorescence in situ hybridization. Am J Phys Anthropol (1995) 1.06
Chromosomal translocations mediated by palindromic DNA. Cell Cycle (2006) 1.06
Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16. Genome Res (2005) 0.98
Segmental duplication associated with the human-specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. Hum Genet (2004) 0.98
Cytogenetic comparison and phylogeny of three species of Hylobatidae. Am J Phys Anthropol (1983) 0.96
Conserved chromosome segments in Hylobates hoolock revealed by human and H. leucogenys paint probes. Cytogenet Cell Genet (2001) 0.95
Identification of complex chromosome rearrangements in the gibbon by fluorescent in situ hybridization (FISH) of a human chromosome 2q specific microlibrary, yeast artificial chromosomes, and reciprocal chromosome painting. Cytogenet Cell Genet (1996) 0.93
Applications of combined DNA microarray and chromosome sorting technologies. Chromosome Res (2004) 0.93
Cross-species colour segmenting: a novel tool in human karyotype analysis. Cytometry (1998) 0.93
The evolutionary history of human chromosome 7. Genomics (2004) 0.92
A presumptive new hylobatid subgenus with 38 chromosomes. Cytogenet Cell Genet (1983) 0.90
Micro-array analyses decipher exceptional complex familial chromosomal rearrangement. Hum Genet (2006) 0.89
[A comparative chromosome map between human and Hylobates hoolock built by chromosome painting]. Yi Chuan Xue Bao (1997) 0.84
[Karyotype analysis of 2 species of gibbons (Hylobates lar and H. concolor) with different banding species]. Cytogenet Cell Genet (1975) 0.82
Molecular evolution of growth hormone gene family in old world monkeys and hominoids. Gene (2005) 0.81
Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. Genomics (2005) 0.80
Endogenous retrovirus HERV-I LTR family in primates: sequences, phylogeny, and evolution. Arch Virol (2006) 0.79
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Accurate whole human genome sequencing using reversible terminator chemistry. Nature (2008) 90.20
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Somatic mutations affect key pathways in lung adenocarcinoma. Nature (2008) 30.02
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution. Nature (2008) 18.84
DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet (2006) 18.08
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med (2013) 13.22
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature (2003) 13.00
Prepublication data sharing. Nature (2009) 12.24
Complete MHC haplotype sequencing for common disease gene mapping. Genome Res (2004) 12.09
A conditional knockout resource for the genome-wide study of mouse gene function. Nature (2011) 9.93
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res (2012) 9.13
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
The amphioxus genome and the evolution of the chordate karyotype. Nature (2008) 8.03
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature (2013) 7.42
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. Genome Res (2007) 6.91
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nat Genet (2004) 6.90
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet (2012) 6.25
The genome of the blood fluke Schistosoma mansoni. Nature (2009) 5.94
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet (2007) 5.68
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature (2005) 5.51
Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res (2006) 5.50
Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities. Am J Hum Genet (2003) 5.43
Rapid whole-genome sequencing for genetic disease diagnosis in neonatal intensive care units. Sci Transl Med (2012) 5.16
A physical map of the mouse genome. Nature (2002) 4.97
The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature (2011) 4.94
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science (2007) 4.89
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics (2007) 4.62
Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. Genome Res (2007) 4.33
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project. Immunogenetics (2008) 4.25
Insights into hominid evolution from the gorilla genome sequence. Nature (2012) 4.12
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res (2008) 4.06
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns. Blood (2012) 3.63
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell (2007) 3.58
An integrative variant analysis suite for whole exome next-generation sequencing data. BMC Bioinformatics (2012) 3.41
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat Methods (2009) 3.35
The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature (2011) 3.32
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol (2012) 3.31
CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet (2010) 3.25
Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks. Cell (2008) 3.25
Nodulation signaling in legumes requires NSP2, a member of the GRAS family of transcriptional regulators. Science (2005) 3.19
A conserved supergene locus controls colour pattern diversity in Heliconius butterflies. PLoS Biol (2006) 3.15
TranscriptSNPView: a genome-wide catalog of mouse coding variation. Nat Genet (2006) 3.10
Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. Genome Biol (2002) 3.09
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res (2008) 3.04
Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am J Hum Genet (2006) 3.00
Construction and analysis of a human-chimpanzee comparative clone map. Science (2002) 2.83
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS Genet (2006) 2.80
Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci. Genome Res (2002) 2.77
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet (2013) 2.76
Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry. Nature (2011) 2.65
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes. PLoS Comput Biol (2009) 2.61
Legume genome evolution viewed through the Medicago truncatula and Lotus japonicus genomes. Proc Natl Acad Sci U S A (2006) 2.61