Published in Nat Biotechnol on September 19, 2010
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Global DNA methylation remodeling accompanies CD8 T cell effector function. J Immunol (2013) 1.27
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Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res (2011) 1.22
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation. Genome Biol (2014) 1.19
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Maternal obesity enhances white adipose tissue differentiation and alters genome-scale DNA methylation in male rat offspring. Endocrinology (2013) 1.09
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Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies. Epigenetics (2013) 1.08
Intermediate DNA methylation is a conserved signature of genome regulation. Nat Commun (2015) 1.07
Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol (2013) 1.07
Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences. Proc Natl Acad Sci U S A (2011) 1.04
"Seq-ing" insights into the epigenetics of neuronal gene regulation. Neuron (2013) 1.03
Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation. PLoS One (2011) 1.02
Unique DNA methylome profiles in CpG island methylator phenotype colon cancers. Genome Res (2011) 1.02
Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique. Epigenetics (2012) 1.02
Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell. PLoS One (2011) 1.01
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Genomic impact of cigarette smoke, with application to three smoking-related diseases. Crit Rev Toxicol (2012) 1.00
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Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing. Nat Commun (2013) 0.99
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Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale. Nucleic Acids Res (2012) 0.98
SAAP-RRBS: streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing. Bioinformatics (2012) 0.98
Understanding the epigenetic syntax for the genetic alphabet in the kidney. J Am Soc Nephrol (2013) 0.98
29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome. PLoS One (2012) 0.97
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Analyzing the cancer methylome through targeted bisulfite sequencing. Cancer Lett (2012) 0.96
Epigenomic alterations in localized and advanced prostate cancer. Neoplasia (2013) 0.96
CpG_MPs: identification of CpG methylation patterns of genomic regions from high-throughput bisulfite sequencing data. Nucleic Acids Res (2012) 0.96
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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
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Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature (2008) 30.29
ZOOM! Zillions of oligos mapped. Bioinformatics (2008) 29.78
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature (2008) 26.78
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat Biotechnol (2008) 21.72
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (2009) 18.82
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Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol (2003) 9.30
Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature (1983) 9.28
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Gene body-specific methylation on the active X chromosome. Science (2007) 6.33
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BSMAP: whole genome bisulfite sequence MAPping program. BMC Bioinformatics (2009) 5.67
Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat Genet (2010) 5.26
Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. Nat Methods (2010) 4.30
Neomorphic agouti mutations in obese yellow mice. Nat Genet (1994) 3.92
MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome. Nucleic Acids Res (2009) 3.29
Updates to the RMAP short-read mapping software. Bioinformatics (2009) 3.18
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Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. Proc Natl Acad Sci U S A (2007) 3.00
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Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum Mol Genet (2006) 2.60
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Moving AHEAD with an international human epigenome project. Nature (2008) 2.38
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Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Stem Cells (2009) 1.98
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Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Hum Mol Genet (2003) 1.80
Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Biotechniques (2007) 1.78
A genome-wide approach to identifying novel-imprinted genes. Hum Genet (2007) 1.55
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A high-resolution map of active promoters in the human genome. Nature (2005) 24.35
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Active genes are tri-methylated at K4 of histone H3. Nature (2002) 15.68
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