Published in Diabetes Obes Metab on January 01, 2007
Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences. Cell (2014) 3.70
Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab (2008) 3.05
Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab (2007) 2.58
Visceral adiposity and its anatomical distribution as predictors of the metabolic syndrome and cardiometabolic risk factor levels. Am J Clin Nutr (2008) 1.80
De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. J Biol Chem (2009) 1.20
Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells. J Biol Chem (2008) 1.05
Implications of crosstalk between leptin and insulin signaling during the development of diet-induced obesity. Biochim Biophys Acta (2008) 1.04
Reproducible MRI measurement of adipose tissue volumes in genetic and dietary rodent obesity models. J Magn Reson Imaging (2008) 0.99
Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity. Diabetologia (2009) 0.97
Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation. PLoS One (2014) 0.94
Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE). Aging (Albany NY) (2008) 0.93
Insulin signaling and life span. Pflugers Arch (2009) 0.90
Intestinal mucosal triacylglycerol accumulation secondary to decreased lipid secretion in obese and high fat fed mice. Front Physiol (2012) 0.89
Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse. Am J Physiol Endocrinol Metab (2011) 0.82
Protective Effects of Oleic Acid Against Palmitic Acid-Induced Apoptosis in Pancreatic AR42J Cells and Its Mechanisms. Korean J Physiol Pharmacol (2013) 0.82
Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity. Nestle Nutr Inst Workshop Ser (2012) 0.81
[Adipokine update - new molecules, new functions]. Wien Med Wochenschr (2010) 0.81
Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age. Age (Dordr) (2015) 0.81
Jiao tai wan attenuates hepatic lipid accumulation in type 2 diabetes mellitus. Evid Based Complement Alternat Med (2013) 0.79
Abdominal adiposity depots are correlates of adverse cardiometabolic risk factors in Caucasian and African-American adults. Nutr Diabetes (2011) 0.79
A paradox: insulin inhibits expression and secretion of resistin which induces insulin resistance. World J Gastroenterol (2008) 0.78
AMPK activation--protean potential for boosting healthspan. Age (Dordr) (2013) 0.78
Long-term risperidone treatment induces visceral adiposity associated with hepatic steatosis in mice: a magnetic resonance approach. Schizophr Res Treatment (2014) 0.77
FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca(2+)/CREB pathway. Aging Cell (2015) 0.76
Antioxidant and antiadipogenic activities of galkeun-tang, a traditional korean herbal formula. Evid Based Complement Alternat Med (2014) 0.75
Neck Circumference May Be a Better Alternative to Standard Anthropometric Measures. J Diabetes Res (2016) 0.75
Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab (2008) 3.11
OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes (2006) 2.77
Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab (2007) 2.58
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J Clin Endocrinol Metab (2008) 2.07
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation. Am J Physiol Endocrinol Metab (2010) 1.94
Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action. Am J Physiol Endocrinol Metab (2009) 1.75
Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue. Am J Physiol Endocrinol Metab (2005) 1.75
Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes (2007) 1.67
Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. J Clin Endocrinol Metab (2011) 1.65
The Genetic Basis of Type 2 Diabetes. Cellscience (2006) 1.58
Increased plasma adiponectin in response to pioglitazone does not result from increased gene expression. Am J Physiol Endocrinol Metab (2005) 1.52
The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment. J Lipid Res (2006) 1.50
Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes (2006) 1.48
Mutation screening and association of human retinoid X receptor gamma variation with lipid levels in familial type 2 diabetes. Mol Genet Metab (2002) 1.44
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. J Clin Endocrinol Metab (2006) 1.42
Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion. Am J Physiol Endocrinol Metab (2003) 1.38
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity. Am J Physiol Endocrinol Metab (2004) 1.36
Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids. Am J Physiol Endocrinol Metab (2008) 1.33
Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin-resistant individuals matched for BMI. Diabetes (2011) 1.31
Oxidative stress in diabetes: a mechanistic overview of its effects on atherogenesis and myocardial dysfunction. Int J Biochem Cell Biol (2006) 1.28
Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression. J Biol Chem (2004) 1.24
The search for type 2 diabetes susceptibility loci: the chromosome 1q story. Curr Diab Rep (2007) 1.22
Pioglitazone induces apoptosis of macrophages in human adipose tissue. J Lipid Res (2006) 1.19
Detection of allelic imbalance in gene expression using pyrosequencing. Methods Mol Biol (2007) 1.19
Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes. Am J Physiol Endocrinol Metab (2006) 1.17
Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans. Arterioscler Thromb Vasc Biol (2009) 1.17
Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans. J Clin Endocrinol Metab (2010) 1.16
Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines. Am J Physiol Endocrinol Metab (2008) 1.15
Retinol binding protein 4 as a candidate gene for type 2 diabetes and prediabetic intermediate traits. Mol Genet Metab (2006) 1.15
An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects. J Clin Endocrinol Metab (2011) 1.11
Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle. J Clin Endocrinol Metab (2010) 1.10
Genetic risk factors for type 2 diabetes: a trans-regulatory genetic architecture? Am J Hum Genet (2012) 1.09
Meta-analysis of genome-wide linkage studies of quantitative lipid traits in families ascertained for type 2 diabetes. Diabetes (2007) 1.08
Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance. Diabetes (2013) 1.08
The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity. J Clin Endocrinol Metab (2009) 1.08
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis. Proc Natl Acad Sci U S A (2013) 1.07
Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness. J Clin Endocrinol Metab (2008) 1.07
Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone. J Clin Endocrinol Metab (2010) 1.05
Social network analysis to assess the impact of the CTSA on biomedical research grant collaboration. Clin Transl Sci (2014) 1.05
Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects. Atherosclerosis (2003) 1.03
Impact of family history of diabetes and ethnicity on -cell function in obese, glucose-tolerant individuals. J Clin Endocrinol Metab (2007) 1.03
Molecular screening and association analyses of the interleukin 6 receptor gene variants with type 2 diabetes, diabetic nephropathy, and insulin sensitivity. J Clin Endocrinol Metab (2004) 1.01
Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians. Diabetes (2004) 0.99
Common variants in glutamine:fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. J Clin Endocrinol Metab (2004) 0.98
Lipotoxicity in diabetic nephropathy: the potential role of fatty acid oxidation. Clin J Am Soc Nephrol (2010) 0.98
Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility locus in northern European Caucasians. Diabetes (2004) 0.98
Human resistin gene: molecular scanning and evaluation of association with insulin sensitivity and type 2 diabetes in Caucasians. J Clin Endocrinol Metab (2002) 0.97
Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone. Metabolism (2010) 0.96
Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects. J Clin Endocrinol Metab (2010) 0.96
Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. Diabetes (2006) 0.95
Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q. Diabetes (2009) 0.95
Distinct gene expression profiles characterize cellular responses to palmitate and oleate. J Lipid Res (2010) 0.94
Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance. Diabetes (2004) 0.94
The translational regulation of lipoprotein lipase by epinephrine involves an RNA binding complex including the catalytic subunit of protein kinase A. J Biol Chem (2002) 0.94
Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits. Diabetes (2007) 0.93
The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation. Atherosclerosis (2011) 0.93
Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes. Ann Epidemiol (2011) 0.93
The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes. Nephrol Dial Transplant (2010) 0.92
Expression of FOXC2 in adipose and muscle and its association with whole body insulin sensitivity. Am J Physiol Endocrinol Metab (2004) 0.91
Transgenic mice expressing lipoprotein lipase in adipose tissue. Absence of the proximal 3'-untranslated region causes translational upregulation. J Biol Chem (2003) 0.91
Improved glycemic control in subjects with atypical diabetes results from restored insulin secretion, but not improved insulin sensitivity. J Clin Endocrinol Metab (2004) 0.90
Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans. BMC Med Genet (2005) 0.90
Univariate and bivariate linkage analysis identifies pleiotropic loci underlying lipid levels and type 2 diabetes risk. Ann Hum Genet (2010) 0.89
Obesity and hepatosteatosis in mice with enhanced oxidative DNA damage processing in mitochondria. Am J Pathol (2011) 0.89
Pleiotropy of type 2 diabetes with obesity. J Hum Genet (2011) 0.89
Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes. Am J Physiol Endocrinol Metab (2006) 0.88
Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study. J Hum Genet (2011) 0.87
Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians. Diabetes (2002) 0.86
The prevention and treatment of metabolic syndrome and high-risk obesity. Curr Opin Cardiol (2006) 0.86
Evaluation of sequence variants in the pre-B cell leukemia transcription factor 1 gene: a positional and functional candidate for type 2 diabetes and impaired insulin secretion. Mol Genet Metab (2005) 0.86
Role of A kinase anchor proteins in the tissue-specific regulation of lipoprotein lipase. Mol Endocrinol (2005) 0.86
Effects of short-term experimental insulin resistance and family history of diabetes on pancreatic beta-cell function in nondiabetic individuals. J Clin Endocrinol Metab (2005) 0.86
DHA reduces the atrophy-associated Fn14 protein in differentiated myotubes during coculture with macrophages. J Nutr Biochem (2011) 0.85
Regulation of thrombospondin-1 expression in alternatively activated macrophages and adipocytes: role of cellular cross talk and omega-3 fatty acids. J Nutr Biochem (2013) 0.84
Calcium is involved in formation of high molecular weight adiponectin. Metab Syndr Relat Disord (2008) 0.84
Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis. BMC Med Genet (2008) 0.84
Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects. Diabetes (2007) 0.84
Effect of endoplasmic reticulum stress on inflammation and adiponectin regulation in human adipocytes. Metab Syndr Relat Disord (2012) 0.83
Visceral fat and adiponectin: associations with insulin resistance are tissue-specific in women. Metab Syndr Relat Disord (2009) 0.82
Alpha-endosulfine, a positional and functional candidate gene for type 2 diabetes: molecular screening, association studies, and role in reduced insulin secretion. Mol Genet Metab (2004) 0.82
Analysis of osteocalcin as a candidate gene for type 2 diabetes (T2D) and intermediate traits in Caucasians and African Americans. Dis Markers (2010) 0.82
Analysis of FOXO1A as a candidate gene for type 2 diabetes. Mol Genet Metab (2006) 0.81
Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes. J Biol Chem (2002) 0.81
Predictors of in-stent restenosis and patient outcome after percutaneous coronary intervention in patients with diabetes mellitus. Am J Cardiol (2007) 0.81
An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects. PLoS One (2013) 0.80
Improved insulin sensitivity after treatment with PPARγ and PPARα ligands is mediated by genetically modulated transcripts. Pharmacogenet Genomics (2012) 0.80
Five linkage regions each harbor multiple type 2 diabetes genes in the African American subset of the GENNID Study. J Hum Genet (2013) 0.80
Allelic expression imbalance screening of genes in chromosome 1q21-24 region to identify functional variants for Type 2 diabetes susceptibility. Physiol Genomics (2013) 0.80
Molecular screening and association studies of retinoid-related orphan receptor gamma (RORC): a positional and functional candidate for type 2 diabetes. Mol Genet Metab (2003) 0.79