Published in J Immunol on January 15, 2007
How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nat Rev Immunol (2009) 2.46
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Natural killer cells in infection and inflammation of the lung. Immunology (2009) 1.46
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes. BMC Med Genomics (2010) 1.22
Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact. PLoS One (2010) 1.11
Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study. Respir Res (2010) 1.07
Decreased NK cells in patients with head and neck cancer determined in archival DNA. Clin Cancer Res (2012) 1.06
Nasal lavage natural killer cell function is suppressed in smokers after live attenuated influenza virus. Respir Res (2011) 1.04
Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke. PLoS One (2010) 1.02
Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke. BMC Med Genomics (2009) 1.01
Cigarette smoke exposure inhibits contact hypersensitivity via the generation of platelet-activating factor agonists. J Immunol (2013) 0.98
Tetrabromobisphenol A has immunosuppressive effects on human natural killer cells. J Immunotoxicol (2009) 0.94
NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol (2012) 0.94
Nicotinic receptor β2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer. PLoS One (2013) 0.82
Differential Effect of Active Smoking on Gene Expression in Male and Female Smokers. J Carcinog Mutagen (2015) 0.82
Perturbation of cellular immune functions in cigarette smokers and protection by palm oil vitamin E supplementation. Nutr J (2013) 0.81
The role of natural killer cells in pulmonary immunosurveillance. Front Biosci (Schol Ed) (2013) 0.81
Brominated flame retardants, tetrabromobisphenol A and hexabromocyclododecane, activate mitogen-activated protein kinases (MAPKs) in human natural killer cells. Cell Biol Toxicol (2014) 0.79
Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats. Nutrients (2013) 0.79
Increased killer immunoglobulin-like receptor expression and functional defects in natural killer cells in lung cancer. Immunology (2011) 0.79
Extracts from presumed "reduced harm" cigarettes induce equivalent or greater toxicity in antigen-presenting cells. Toxicology (2015) 0.78
Systemic lupus erythematosus, pregnancy and carcinoma of the tongue. BMJ Case Rep (2013) 0.77
Tobacco smoke-induced immunologic changes may contribute to oral carcinogenesis. J Investig Med (2014) 0.77
The Impact of Smoking on Sentinel Node Metastasis of Primary Cutaneous Melanoma. Ann Surg Oncol (2017) 0.75
Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med (2013) 4.14
TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection. J Clin Invest (2004) 1.76
Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile. Am J Respir Crit Care Med (2009) 1.61
Mutation analysis of the small heat shock protein 27 gene in chinese patients with Charcot-Marie-Tooth disease. Arch Neurol (2005) 1.59
Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection. Am J Respir Crit Care Med (2004) 1.47
Potentiating cancer immunotherapy using an oncolytic virus. Mol Ther (2010) 1.46
Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol (2003) 1.46
Cigarette smoke impacts immune inflammatory responses to influenza in mice. Am J Respir Crit Care Med (2006) 1.38
Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proc Natl Acad Sci U S A (2004) 1.37
IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice. PLoS One (2011) 1.37
Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J Immunol (2007) 1.32
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L. Hum Genet (2004) 1.30
Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages. Am J Respir Cell Mol Biol (2007) 1.27
Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein. Glia (2007) 1.26
Innate immune processes are sufficient for driving cigarette smoke-induced inflammation in mice. Am J Respir Cell Mol Biol (2009) 1.23
Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus. Mol Ther (2009) 1.22
Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice. Am J Respir Cell Mol Biol (2003) 1.18
Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J Leukoc Biol (2007) 1.17
HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy. Mol Ther (2013) 1.13
Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy. Mol Ther (2010) 1.12
Chronic exposure to innocuous antigen in sensitized mice leads to suppressed airway eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. J Immunol (2002) 1.12
Engineering dendritic cells to enhance cancer immunotherapy. Mol Ther (2011) 1.10
Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin. Cancer Res (2004) 1.08
Mainstream tobacco smoke causes paternal germ-line DNA mutation. Cancer Res (2007) 1.06
Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines. Curr Gene Ther (2005) 1.04
Amygdala cyclic adenosine monophosphate response element binding protein phosphorylation in patients with mood disorders: effects of diagnosis, suicide, and drug treatment. Biol Psychiatry (2004) 1.03
Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus. J Virol (2009) 1.02
On the role of CD4+ T cells in the CD8+ T-cell response elicited by recombinant adenovirus vaccines. Mol Ther (2007) 1.01
Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. PLoS One (2010) 1.01
Recombinant vesicular stomatitis virus transduction of dendritic cells enhances their ability to prime innate and adaptive antitumor immunity. Mol Ther (2009) 1.00
Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells. J Interferon Cytokine Res (2008) 0.99
Cigarette smoke and platelet-activating factor receptor dependent adhesion of Streptococcus pneumoniae to lower airway cells. Thorax (2012) 0.98
Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke. Am J Respir Crit Care Med (2011) 0.98
Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses. J Immunol (2005) 0.98
Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation. J Immunol (2013) 0.98
Neoadjuvant vaccination provides superior protection against tumor relapse following surgery compared with adjuvant vaccination. Cancer Res (2009) 0.97
Cigarette smoke exposure leads to follicle loss via an alternative ovarian cell death pathway in a mouse model. Toxicol Sci (2011) 0.97
IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells. Cancer Res (2011) 0.97
Elevated frequencies of self-reactive CD8+ T cells following immunization with a xenoantigen are due to the presence of a heteroclitic CD4+ T-cell helper epitope. Cancer Res (2007) 0.97
Adjuvant and anti-inflammatory properties of cigarette smoke in murine allergic airway inflammation. Am J Respir Cell Mol Biol (2008) 0.95
Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells. Mol Ther (2007) 0.95
ATM activity contributes to the tumor-suppressing functions of p14ARF. Oncogene (2004) 0.95
Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice. Respir Res (2012) 0.94
Desipramine treatment reduces the long-term behavioural and neurochemical sequelae of early-life maternal separation. Int J Neuropsychopharmacol (2003) 0.93
Nanocomposites of size-controlled gold nanoparticles and graphene oxide: formation and applications in SERS and catalysis. Nanoscale (2010) 0.93
Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patients. Oncoimmunology (2012) 0.92
Clinical heterogeneity in patients with early-stage Parkinson's disease: a cluster analysis. J Zhejiang Univ Sci B (2011) 0.91
Polyamidoamine-grafted multiwalled carbon nanotubes for gene delivery: synthesis, transfection and intracellular trafficking. Bioconjug Chem (2011) 0.90
Localization and mutation detection for paroxysmal kinesigenic choreoathetosis. J Mol Neurosci (2007) 0.90
Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4. Am J Respir Cell Mol Biol (2002) 0.90
Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. Atherosclerosis (2002) 0.90
Regulation of ER stress proteins by valproate: therapeutic implications. Bipolar Disord (2002) 0.89
Cigarette smoke exposure elicits increased autophagy and dysregulation of mitochondrial dynamics in murine granulosa cells. Biol Reprod (2013) 0.89
Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8(+) T-cell responses to anticancer vaccines. Oncoimmunology (2013) 0.88
Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen. J Immunol (2010) 0.88
Autophagy facilitates major histocompatibility complex class I expression induced by IFN-γ in B16 melanoma cells. Cancer Immunol Immunother (2010) 0.88
[The relationship between body mass index, hypertension and all-cause mortality in the populaton over 55 year old in Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi (2002) 0.88
Tolerogenic dendritic cells and their potential applications. Immunology (2011) 0.88
A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer. Cancer Gene Ther (2003) 0.88
The influence of cigarette smoking on viral infections: translating bench science to impact COPD pathogenesis and acute exacerbations of COPD clinically. Chest (2013) 0.87
Mechanism of cellular uptake of graphene oxide studied by surface-enhanced Raman spectroscopy. Small (2012) 0.87
Structure-based prediction of the effects of a missense variant on protein stability. Amino Acids (2012) 0.87
On the generation of allergic airway diseases: from GM-CSF to Kyoto. Trends Immunol (2002) 0.86
Mucosally delivered dendritic cells activate T cells independently of IL-12 and endogenous APCs. J Immunol (2008) 0.86
CTL-dependent and -independent antitumor immunity is determined by the tumor not the vaccine. J Immunol (2004) 0.86
Adenoviral-mediated gene transfer of lymphotactin to the lungs of mice and rats results in infiltration and direct accumulation of CD4+, CD8+, and NK cells. J Interferon Cytokine Res (2002) 0.86
Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. Am J Physiol Lung Cell Mol Physiol (2007) 0.86
Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8(+) T-cell recall responses. Blood (2013) 0.85
Detection of lung dysfunction using ventilation and perfusion SPECT in a mouse model of chronic cigarette smoke exposure. J Nucl Med (2013) 0.85
Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-beta production. Mol Immunol (2008) 0.85
Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression. Exp Cell Res (2006) 0.85
T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice. J Appl Physiol (1985) (2004) 0.84
Culture of myeloid dendritic cells from bone marrow precursors. J Vis Exp (2008) 0.84
Vitamin D receptor gene polymorphism and its association with Parkinson's disease in Chinese Han population. Neurosci Lett (2012) 0.84
The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector. Cell Immunol (2008) 0.83
B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance. J Immunol (2005) 0.83
ACT and UCH-L1 polymorphisms in Parkinson's disease and age of onset. Mov Disord (2002) 0.83
Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models. Pulm Pharmacol Ther (2012) 0.82
ORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic. Mol Ther (2012) 0.82
Interleukin-18 promoter polymorphisms and risk of Parkinson's disease in a Han Chinese population. Brain Res (2011) 0.82
Controlled assembly of Fe3O4 magnetic nanoparticles on graphene oxide. Nanoscale (2011) 0.81
Expression of DNA-PKcs and BRCA1 as prognostic indicators in nasopharyngeal carcinoma following intensity-modulated radiation therapy. Oncol Lett (2013) 0.81
Interleukin-10 promoter polymorphisms in Chinese patients with Parkinson's disease. Neurosci Lett (2012) 0.81
Preliminary studies on Alzheimer's disease using cDNA microarrays. Mech Ageing Dev (2003) 0.81
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues. J Immunol (2006) 0.81
CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis. Eur J Immunol (2009) 0.81
Mutation frequency for Charcot-Marie-Tooth disease type 1 in the Chinese population is similar to that in the global ethnic patients. Genet Med (2006) 0.80
Prolonged ovalbumin exposure attenuates airway hyperresponsiveness and T cell function in mice. Int Arch Allergy Immunol (2006) 0.80
Animal models of chronic obstructive pulmonary disease exacerbations. Contrib Microbiol (2007) 0.80