Published in J Immunol on January 15, 2007
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol (2008) 2.58
Matrix metalloproteinases as modulators of inflammation. Semin Cell Dev Biol (2007) 2.14
Fragments of extracellular matrix as mediators of inflammation. Int J Biochem Cell Biol (2007) 1.89
Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain. J Virol (2008) 1.49
Matrix metalloproteinases as drug targets in infections caused by gram-negative bacteria and in septic shock. Clin Microbiol Rev (2009) 1.49
Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis. Immunol Rev (2008) 1.48
Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses (2015) 1.43
Immunity to Francisella. Front Microbiol (2011) 1.37
Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen. J Immunol (2008) 1.36
An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain. Vaccine (2008) 1.35
A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation. PLoS One (2011) 1.34
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. Am J Pathol (2008) 1.33
Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB J (2008) 1.27
Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection. PLoS Pathog (2008) 1.25
The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation. J Immunol (2009) 1.21
Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis. J Leukoc Biol (2010) 1.18
Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan. J Immunol (2012) 1.18
Role of the pulmonary epithelium and inflammatory signals in acute lung injury. Expert Rev Clin Immunol (2009) 1.10
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia. J Immunol (2008) 1.09
Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species. J Bacteriol (2009) 1.05
Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemia. PLoS One (2012) 1.04
Francisella tularensis induces ubiquitin-dependent major histocompatibility complex class II degradation in activated macrophages. Infect Immun (2009) 1.04
Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum. J Immunol (2012) 1.00
Attacking the multi-tiered proteolytic pathology of COPD: new insights from basic and translational studies. Pharmacol Ther (2008) 0.99
Development of tolerogenic dendritic cells and regulatory T cells favors exponential bacterial growth and survival during early respiratory tularemia. J Leukoc Biol (2011) 0.98
Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. Am J Physiol Heart Circ Physiol (2010) 0.98
Differential requirements for protection against mucosal challenge with Francisella tularensis in the presence versus absence of cholera toxin B and inactivated F. tularensis. J Immunol (2009) 0.97
Proline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation. Open Respir Med J (2010) 0.96
Host Defense and the Airway Epithelium: Frontline Responses That Protect against Bacterial Invasion and Pneumonia. J Pathog (2011) 0.92
A galU mutant of Francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia. BMC Microbiol (2011) 0.91
Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae. J Immunol (2011) 0.90
Rapid dissemination of Francisella tularensis and the effect of route of infection. BMC Microbiol (2008) 0.90
MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro. PLoS One (2012) 0.89
Matrix metalloproteinase 9 plays a key role in lyme arthritis but not in dissemination of Borrelia burgdorferi. Infect Immun (2009) 0.89
Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesis. J Bacteriol (2009) 0.88
Host-pathogen interactions and immune evasion strategies in Francisella tularensis pathogenicity. Infect Drug Resist (2014) 0.87
Interfering with extracellular matrix degradation to blunt inflammation. Curr Opin Pharmacol (2008) 0.87
Hospital acquired pneumonia with high-risk bacteria is associated with increased pulmonary matrix metalloproteinase activity. BMC Pulm Med (2008) 0.86
Neutrophils: potential therapeutic targets in tularemia? Front Cell Infect Microbiol (2013) 0.86
An Immature Myeloid/Myeloid-Suppressor Cell Response Associated with Necrotizing Inflammation Mediates Lethal Pulmonary Tularemia. PLoS Pathog (2016) 0.85
T-bet regulates immunity to Francisella tularensis live vaccine strain infection, particularly in lungs. Infect Immun (2014) 0.83
Pulmonary matrix metalloproteinase-9 activity in mechanically ventilated children with respiratory syncytial virus. Eur Respir J (2013) 0.83
The capBCA Locus is Required for Intracellular Growth of Francisella tularensis LVS. Front Microbiol (2011) 0.83
Does Type I Interferon Limit Protective Neutrophil Responses during Pulmonary Francisella Tularensis Infection? Front Immunol (2014) 0.83
Editorial: Leukocytes in tularemia--so many cells, so little time. J Leukoc Biol (2013) 0.79
CD14 signaling reciprocally controls collagen deposition and turnover to regulate the development of lyme arthritis. Am J Pathol (2011) 0.79
Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease. PLoS Pathog (2015) 0.78
Francisella tularensis Modulates a Distinct Subset of Regulatory Factors and Sustains Mitochondrial Integrity to Impair Human Neutrophil Apoptosis. J Innate Immun (2016) 0.77
Matrix Metalloproteinase 9 Exerts Antiviral Activity against Respiratory Syncytial Virus. PLoS One (2015) 0.77
Hematopoiesis in mice is extremely resilient to wide variation in TIMP/MMP balance. Blood Cells Mol Dis (2008) 0.77
The contribution of the glycine cleavage system to the pathogenesis of Francisella tularensis. Microbes Infect (2013) 0.77
Proteomic analysis of bronchoalveolar lavage fluid proteins from mice infected with Francisella tularensis ssp. novicida. J Proteome Res (2012) 0.77
A Protective Role for Macrophages in Respiratory Francisella tularensis Infection. Infect Immun (2017) 0.76
Role of Matrix Metalloproteinases 2 and 9 in Lacrimal Gland Disease in Animal Models of Sjögren's Syndrome. Invest Ophthalmol Vis Sci (2015) 0.76
Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis. Mol Med (2013) 0.76
Multifaceted effects of Francisella tularensis on human neutrophil function and lifespan. Immunol Rev (2016) 0.76
MyD88-dependent signaling prolongs survival and reduces bacterial burden during pulmonary infection with virulent Francisella tularensis. Am J Pathol (2013) 0.76
Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge. Front Cell Infect Microbiol (2011) 0.76
Matrix metalloproteinases contribute to the regulation of chemokine expression and pulmonary inflammation in Cryptococcus infection. Clin Exp Immunol (2015) 0.75
Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. J Leukoc Biol (2016) 0.75
Francisella novicida inhibits spontaneous apoptosis and extends human neutrophil lifespan. J Leukoc Biol (2017) 0.75
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol (2006) 5.51
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med (2006) 5.05
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem (2002) 4.48
Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection. Nat Med (2008) 3.67
West Nile virus 5'-cap structure is formed by sequential guanine N-7 and ribose 2'-O methylations by nonstructural protein 5. J Virol (2006) 3.07
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol (2008) 2.58
A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science (2010) 2.56
Toll-like receptor 2 is required for control of pulmonary infection with Francisella tularensis. Infect Immun (2006) 2.12
The ups and downs of peer review. Adv Physiol Educ (2007) 2.04
Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med (2004) 2.02
Intranasal interleukin-12 treatment for protection against respiratory infection with the Francisella tularensis live vaccine strain. Infect Immun (2005) 1.97
Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation. J Mol Cell Cardiol (2006) 1.96
Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function. Am J Respir Crit Care Med (2013) 1.93
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation. J Biol Chem (2005) 1.88
Estrogen modulates TNF-alpha-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-beta activation. Am J Physiol Heart Circ Physiol (2007) 1.80
Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect Immun (2007) 1.64
Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med (2008) 1.62
Prophylactic and therapeutic use of antibodies for protection against respiratory infection with Francisella tularensis. J Immunol (2007) 1.61
Francisella tularensis has a significant extracellular phase in infected mice. J Infect Dis (2007) 1.58
Inactivated Francisella tularensis live vaccine strain protects against respiratory tularemia by intranasal vaccination in an immunoglobulin A-dependent fashion. Infect Immun (2007) 1.57
Stimulation of NF-κB activity by the HIV restriction factor BST2. J Virol (2012) 1.56
Coevolution of markers of innate and adaptive immunity in skin and peripheral blood of patients with erythema migrans. J Immunol (2003) 1.53
Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections. J Immunol (2010) 1.52
Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells. Cancer Res (2007) 1.52
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD. Respir Res (2009) 1.50
Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis. Immunol Rev (2008) 1.48
Early activation of NK cells after lung infection with the intracellular bacterium, Francisella tularensis LVS. Cell Immunol (2005) 1.47
Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence. Proc Natl Acad Sci U S A (2006) 1.45
Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. Nat Struct Mol Biol (2012) 1.42
Mucosal immunopathogenesis of Francisella tularensis. Ann N Y Acad Sci (2007) 1.39
Seasonal FluMist vaccination induces cross-reactive T cell immunity against H1N1 (2009) influenza and secondary bacterial infections. J Immunol (2010) 1.38
Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis. J Immunol (2008) 1.36
Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta. Proc Natl Acad Sci U S A (2011) 1.36
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi. Proc Natl Acad Sci U S A (2008) 1.35
An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain. Vaccine (2008) 1.35
A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation. PLoS One (2011) 1.34
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. Am J Pathol (2008) 1.33
Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence. J Bacteriol (2006) 1.33
Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD. Chest (2013) 1.32
Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB J (2008) 1.27
Elevated sod2 activity augments matrix metalloproteinase expression: evidence for the involvement of endogenous hydrogen peroxide in regulating metastasis. Clin Cancer Res (2003) 1.27
Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteries. Circulation (2004) 1.26
Adaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro. Infect Immun (2008) 1.25
Two DHH subfamily 1 proteins in Streptococcus pneumoniae possess cyclic di-AMP phosphodiesterase activity and affect bacterial growth and virulence. J Bacteriol (2013) 1.24
Manganese superoxide dismutase (Sod2) and redox-control of signaling events that drive metastasis. Anticancer Agents Med Chem (2011) 1.24
Men's extramarital sex, marital relationships and sexual risk in urban poor communities in India. J Urban Health (2006) 1.23
Indicators of mobility, socio-economic vulnerabilities and HIV risk behaviours among mobile female sex workers in India. AIDS Behav (2012) 1.23
A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary influenza A virus infection. J Virol (2010) 1.22
The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation. J Immunol (2009) 1.21
Design of a protective single-dose intranasal nanoparticle-based vaccine platform for respiratory infectious diseases. PLoS One (2011) 1.20
Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. Infect Immun (2003) 1.19
Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation. Proc Natl Acad Sci U S A (2004) 1.19
Is there a doctor in the house? The downside of 24/7 attending coverage in academic intensive care units. Am J Respir Crit Care Med (2010) 1.18
Delivery of IL-12 intranasally leads to reduced IL-12-mediated toxicity. Int Immunopharmacol (2003) 1.16
Cyclic di-AMP impairs potassium uptake mediated by a cyclic di-AMP binding protein in Streptococcus pneumoniae. J Bacteriol (2013) 1.16
Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. Am J Physiol Lung Cell Mol Physiol (2010) 1.15
Fibrosis: ultimate and proximate causes. J Clin Invest (2014) 1.15
Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS). DNA Cell Biol (2008) 1.14
Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production. J Biol Chem (2010) 1.12
Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase. J Cell Physiol (2010) 1.12
Signaling through CD14 attenuates the inflammatory response to Borrelia burgdorferi, the agent of Lyme disease. J Immunol (2005) 1.11
Altered redox status accompanies progression to metastatic human bladder cancer. Free Radic Biol Med (2008) 1.11
Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide- and Escherichia coli-induced systemic inflammation. Am J Physiol Regul Integr Comp Physiol (2012) 1.10
Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen. J Neuroimmunol (2009) 1.09
Genetic and reproductive knowledge among adolescents and adults with cystic fibrosis. Chest (2008) 1.07
Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain. Biochem J (2003) 1.07
Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation. J Biol Chem (2011) 1.07
CD14 signaling restrains chronic inflammation through induction of p38-MAPK/SOCS-dependent tolerance. PLoS Pathog (2009) 1.06
Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species. J Bacteriol (2009) 1.05