Published in J Synchrotron Radiat on December 15, 2006
Radiation damage in macromolecular crystallography: what is it and why should we care? Acta Crystallogr D Biol Crystallogr (2010) 2.82
Hydrocarbon hydroxylation by cytochrome P450 enzymes. Chem Rev (2010) 2.34
Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures. Proc Natl Acad Sci U S A (2009) 1.88
Significantly shorter Fe-S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidase. Nat Chem (2015) 1.44
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. J Biol Chem (2008) 1.37
Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450. J Phys Chem A (2008) 1.30
2.3 A X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis. Biochemistry (2008) 1.26
The design of macromolecular crystallography diffraction experiments. Acta Crystallogr D Biol Crystallogr (2011) 1.17
Unique heme-iron coordination by the hemoglobin receptor IsdB of Staphylococcus aureus. Biochemistry (2011) 1.16
Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes. Proc Natl Acad Sci U S A (2006) 1.11
Temperature-dependent macromolecular X-ray crystallography. Acta Crystallogr D Biol Crystallogr (2010) 1.09
A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source. J Synchrotron Radiat (2009) 1.07
Synergy within structural biology of single crystal optical spectroscopy and X-ray crystallography. Curr Opin Struct Biol (2007) 0.99
Correlated single-crystal electronic absorption spectroscopy and X-ray crystallography at NSLS beamline X26-C. J Synchrotron Radiat (2011) 0.97
Exploiting fast detectors to enter a new dimension in room-temperature crystallography. Acta Crystallogr D Biol Crystallogr (2014) 0.97
A new on-axis micro-spectrophotometer for combining Raman, fluorescence and UV/Vis absorption spectroscopy with macromolecular crystallography at the Swiss Light Source. J Synchrotron Radiat (2013) 0.96
Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr D Biol Crystallogr (2013) 0.94
Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(omega)-hydroxy-L-arginine and diatomic ligands. Biochemistry (2009) 0.93
Synchrotron X-ray-induced photoreduction of ferric myoglobin nitrite crystals gives the ferrous derivative with retention of the O-bonded nitrite ligand. Biochemistry (2010) 0.93
Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: ASP235 plays divergent roles in different enzyme-catalyzed processes. J Biol Chem (2011) 0.93
Kinetic modeling of the X-ray-induced damage to a metalloprotein. J Phys Chem B (2013) 0.92
Revealing low-dose radiation damage using single-crystal spectroscopy. J Synchrotron Radiat (2011) 0.92
Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency. J Am Chem Soc (2010) 0.91
Laue crystal structure of Shewanella oneidensis cytochrome c nitrite reductase from a high-yield expression system. J Biol Inorg Chem (2012) 0.90
To scavenge or not to scavenge: that is the question. Acta Crystallogr D Biol Crystallogr (2009) 0.89
Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallogr D Biol Crystallogr (2013) 0.89
Setting an upper limit on the myoglobin iron(IV)hydroxide pK(a): insight into axial ligand tuning in heme protein catalysis. J Am Chem Soc (2014) 0.88
Rapid X-ray photoreduction of dimetal-oxygen cofactors in ribonucleotide reductase. J Biol Chem (2013) 0.87
Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data. Acta Crystallogr D Biol Crystallogr (2015) 0.84
Structural and kinetic studies of imidazole binding to two members of the cytochrome c (6) family reveal an important role for a conserved heme pocket residue. J Biol Inorg Chem (2011) 0.81
Development of an online UV-visible microspectrophotometer for a macromolecular crystallography beamline. J Synchrotron Radiat (2013) 0.80
Structures of the substrate-free and product-bound forms of HmuO, a heme oxygenase from corynebacterium diphtheriae: x-ray crystallography and molecular dynamics investigation. J Biol Chem (2013) 0.79
Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography. J Biochem (2016) 0.78
Conformational control of the binding of diatomic gases to cytochrome c'. J Biol Inorg Chem (2015) 0.78
From protein structure to function via single crystal optical spectroscopy. Front Mol Biosci (2015) 0.77
Structural and functional characterization of a cytochrome P450 2B4 F429H mutant with an axial thiolate-histidine hydrogen bond. Biochemistry (2014) 0.77
Cryoradiolysis and cryospectroscopy for studies of heme-oxygen intermediates in cytochromes p450. Methods Mol Biol (2012) 0.77
Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins. J Biol Inorg Chem (2014) 0.76
Comparison of the Mechanisms of Heme Hydroxylation by Heme Oxygenases-1 and -2: Kinetic and Cryoreduction Studies. Biochemistry (2015) 0.75
Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. IUCrJ (2016) 0.75
A nearly on-axis spectroscopic system for simultaneously measuring UV-visible absorption and X-ray diffraction in the SPring-8 structural genomics beamline. J Synchrotron Radiat (2016) 0.75
Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction. IUCrJ (2017) 0.75
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7. F1000Res (2015) 0.75
Femtosecond X-ray protein nanocrystallography. Nature (2011) 14.34
A genetically encoded photoactivatable Rac controls the motility of living cells. Nature (2009) 7.25
High-resolution protein structure determination by serial femtosecond crystallography. Science (2012) 6.90
Structure and chemistry of cytochrome P450. Chem Rev (2005) 5.85
Single mimivirus particles intercepted and imaged with an X-ray laser. Nature (2011) 4.63
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nat Photonics (2012) 3.68
The molecular organization of cypovirus polyhedra. Nature (2007) 3.02
Lipidic phase membrane protein serial femtosecond crystallography. Nat Methods (2012) 2.76
In vivo protein crystallization opens new routes in structural biology. Nat Methods (2012) 2.69
Determination of X-ray flux using silicon pin diodes. J Synchrotron Radiat (2009) 2.44
Time-resolved protein nanocrystallography using an X-ray free-electron laser. Opt Express (2012) 2.38
A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. PLoS Biol (2011) 2.27
Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature (2009) 2.15
Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. Biophys J (2003) 2.08
Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser. Phys Rev B Condens Matter Mater Phys (2011) 2.05
Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures. Proc Natl Acad Sci U S A (2009) 1.88
Crystal structure and mechanism of a DNA (6-4) photolyase. Angew Chem Int Ed Engl (2008) 1.76
Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E. J Mol Biol (2004) 1.60
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. Proc Natl Acad Sci U S A (2004) 1.57
The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Biol (2003) 1.54
Structure of a bacterial BLUF photoreceptor: insights into blue light-mediated signal transduction. Proc Natl Acad Sci U S A (2005) 1.43
Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser. Acta Crystallogr D Biol Crystallogr (2013) 1.42
Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment. Nat Struct Mol Biol (2013) 1.38
Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Mol Cell (2003) 1.37
Optimal fine φ-slicing for single-photon-counting pixel detectors. Acta Crystallogr D Biol Crystallogr (2011) 1.36
Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae. J Biol Chem (2007) 1.33
A survey of active site access channels in cytochromes P450. J Inorg Biochem (2004) 1.32
Tryptophan synthase: the workings of a channeling nanomachine. Trends Biochem Sci (2008) 1.31
Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proc Natl Acad Sci U S A (2008) 1.29
Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family. Proc Natl Acad Sci U S A (2012) 1.29
Unsupervised classification of single-particle X-ray diffraction snapshots by spectral clustering. Opt Express (2011) 1.27
Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding. Science (2005) 1.27
Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proc Natl Acad Sci U S A (2006) 1.26
Crystal structures of the AppA BLUF domain photoreceptor provide insights into blue light-mediated signal transduction. J Mol Biol (2006) 1.24
The status of high-valent metal oxo complexes in the P450 cytochromes. J Inorg Biochem (2006) 1.22
The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses. Proc Natl Acad Sci U S A (2009) 1.17
Crystallography on a chip. Acta Crystallogr D Biol Crystallogr (2012) 1.17
Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis. J Biol Chem (2002) 1.16
Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3. Structure (2006) 1.15
X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction. J Am Chem Soc (2004) 1.15
Structures of nitric oxide synthase isoforms complexed with the inhibitor AR-R17477 suggest a rational basis for specificity and inhibitor design. Proc Natl Acad Sci U S A (2004) 1.11
Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes. Proc Natl Acad Sci U S A (2006) 1.11
Structural aspects of ligand binding to and electron transfer in bacterial and fungal P450s. Annu Rev Biochem (2004) 1.09
Femtosecond free-electron laser x-ray diffraction data sets for algorithm development. Opt Express (2012) 1.07
A new on-axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source. J Synchrotron Radiat (2009) 1.07
Molecular models predict light-induced glutamine tautomerization in BLUF photoreceptors. Biophys J (2008) 1.05
Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis. J Biol Chem (2003) 1.05
X-ray and NMR crystallography in an enzyme active site: the indoline quinonoid intermediate in tryptophan synthase. J Am Chem Soc (2010) 1.05
Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers. Opt Express (2013) 1.04
X-ray beam-position monitoring in the sub-micrometre and sub-second regime. J Synchrotron Radiat (2005) 1.04
Serial femtosecond X-ray diffraction of 30S ribosomal subunit microcrystals in liquid suspension at ambient temperature using an X-ray free-electron laser. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 1.04
Crystal structure of the human supernatant protein factor. Structure (2002) 1.03
Optimal mapping of x-ray laser diffraction patterns into three dimensions using routing algorithms. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 1.03
Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry. Biochemistry (2007) 1.02
Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase-structural models of the short-lived oxygen complexes. Arch Biochem Biophys (2003) 1.02
Crystal structure of ultralente--a microcrystalline insulin suspension. Proteins (2009) 1.01
Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine. Proc Natl Acad Sci U S A (2009) 1.01
Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. Eur Heart J (2012) 1.01
A ternary AppA-PpsR-DNA complex mediates light regulation of photosynthesis-related gene expression. Nat Struct Mol Biol (2013) 1.01
Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res (2012) 0.99
Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms. J Biol Chem (2003) 0.99
Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands. Biochemistry (2007) 0.98
Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate. Chembiochem (2008) 0.98
Sensing the wavefront of x-ray free-electron lasers using aerosol spheres. Opt Express (2013) 0.97
A new on-axis micro-spectrophotometer for combining Raman, fluorescence and UV/Vis absorption spectroscopy with macromolecular crystallography at the Swiss Light Source. J Synchrotron Radiat (2013) 0.96
Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr D Biol Crystallogr (2005) 0.96
Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex. Biochemistry (2007) 0.96
Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector. J Synchrotron Radiat (2011) 0.96
Quantum mechanical/molecular mechanical study on the mechanisms of compound I formation in the catalytic cycle of chloroperoxidase: an overview on heme enzymes. J Phys Chem B (2008) 0.94
Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain. J Biol Chem (2006) 0.94
Crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate. J Biol Chem (2006) 0.94
Tryptophan synthase, an allosteric molecular factory. Curr Opin Chem Biol (2008) 0.93
Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases. J Med Chem (2005) 0.93
The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes. Proc Natl Acad Sci U S A (2009) 0.92
A fast selenium derivatization strategy for crystallization and phasing of RNA structures. RNA (2009) 0.91
Coherent infrared emission from myoglobin crystals: an electric field measurement. Proc Natl Acad Sci U S A (2002) 0.91
On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J Mol Biol (2002) 0.91
Evolution of a new enzyme for carbon disulphide conversion by an acidothermophilic archaeon. Nature (2011) 0.89
Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry (2008) 0.89
Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry (2010) 0.89
A new lectin family with structure similarity to actinoporins revealed by the crystal structure of Xerocomus chrysenteron lectin XCL. J Mol Biol (2004) 0.88