Published in Proc Natl Acad Sci U S A on January 09, 2007
The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol (2010) 2.64
Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB. Immunity (2012) 2.04
Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1. Cold Spring Harb Perspect Biol (2010) 1.95
NF-κB signaling pathways regulated by CARMA family of scaffold proteins. Cell Res (2010) 1.58
CARMA1-mediated NF-kappaB and JNK activation in lymphocytes. Immunol Rev (2009) 1.44
Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. Proc Natl Acad Sci U S A (2008) 1.42
The IκB kinase complex in NF-κB regulation and beyond. EMBO Rep (2013) 1.32
IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells. J Exp Med (2007) 1.19
Regulation of NF-κB by the CARD proteins. Immunol Rev (2012) 1.12
A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol (2012) 1.06
Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth. J Biol Chem (2013) 1.01
MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity. Mol Cell Biol (2009) 0.98
The dynamic distribution of CARD11 at the immunological synapse is regulated by the inhibitory kinesin GAKIN. Mol Cell (2010) 0.98
A new look at T cell receptor signaling to nuclear factor-κB. Trends Immunol (2013) 0.97
Serine 649 phosphorylation within the protein kinase C-regulated domain down-regulates CARMA1 activity in lymphocytes. J Immunol (2009) 0.93
COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation. EMBO Rep (2009) 0.93
The ubiquitin-proteasome system and cardiovascular disease. Prog Mol Biol Transl Sci (2012) 0.93
Chronic activation of the kinase IKKβ impairs T cell function and survival. J Immunol (2012) 0.91
Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex. Proc Natl Acad Sci U S A (2013) 0.88
On to the road to degradation: atherosclerosis and the proteasome. Cardiovasc Res (2009) 0.85
TCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade. Biochem Biophys Res Commun (2014) 0.81
Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. J Immunol (2012) 0.80
L-CBM signaling in lymphocyte development and function. J Blood Med (2010) 0.79
Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation. Mol Cell Biol (2013) 0.79
Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181. Mol Cell Biol (2015) 0.77
Dysfunction of the ubiquitin-proteasome system in atherosclerotic cardiovascular disease. Am J Cardiovasc Dis (2015) 0.77
CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship. Cell Death Dis (2017) 0.75
The CBM signalosome: potential therapeutic target for aggressive lymphoma? Cytokine Growth Factor Rev (2013) 0.75
Virgin olive oil rich in phenolic compounds modulates the expression of atherosclerosis-related genes in vascular endothelium. Eur J Nutr (2015) 0.75
Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol (2005) 8.06
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. Mol Cell (2003) 5.31
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell (2004) 5.08
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell (2000) 4.19
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell (1999) 4.04
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature (2003) 3.96
A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet (1999) 3.93
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell (2001) 3.80
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science (2005) 3.74
Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase. Science (2003) 3.28
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Curr Biol (2003) 2.51
Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem (2001) 2.41
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B. J Biol Chem (2001) 2.25
CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. Mol Cell Biol (2004) 1.96
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation. Mol Cell (2006) 1.78
A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol (2002) 1.77
Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling. Mol Cell Biol (2004) 1.72
Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation. FEBS Lett (2001) 1.66
Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction. J Biol Chem (2001) 1.56
Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B. J Biol Chem (2001) 1.45
Deciphering the pathway from the TCR to NF-kappaB. Cell Death Differ (2006) 1.26
T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10. Blood (2001) 1.26
Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity. Oncogene (1999) 1.22
Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor. Immunity (2003) 1.18
Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha. J Biol Chem (1997) 1.13
BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma. Am J Pathol (2000) 1.13
Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation. J Biol Chem (2003) 1.01
A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus. J Biol Chem (2005) 0.98
CTNNB1 mutations and beta-catenin expression in endometrial carcinomas. Hum Pathol (2002) 0.98
Comparison of the SUMO1 and ubiquitin conjugation pathways during the inhibition of proteasome activity with evidence of SUMO1 recycling. Biochem J (2005) 0.95
MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10. Blood (2005) 0.93
STD and TRNOESY NMR studies on the conformation of the oncogenic protein beta-catenin containing the phosphorylated motif DpSGXXpS bound to the beta-TrCP protein. J Biol Chem (2005) 0.85
Point mutations and deletions of the Bcl10 gene in solid tumors and malignant lymphomas. Cancer Res (1999) 0.84
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature (2003) 6.11
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. Nat Immunol (2012) 2.38
Mature T cells depend on signaling through the IKK complex. Immunity (2003) 2.21
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med (2006) 2.18
NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain. EMBO J (2009) 2.07
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency. J Clin Invest (2003) 1.92
Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. J Cell Biol (2004) 1.79
The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation. PLoS Biol (2010) 1.77
Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains. EMBO Rep (2006) 1.72
NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling. Mol Cell Biol (2006) 1.51
NEMO trimerizes through its coiled-coil C-terminal domain. J Biol Chem (2002) 1.41
From calcium to NF-kappa B signaling pathways in neurons. Mol Cell Biol (2003) 1.38
A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution. J Biol Chem (2004) 1.37
Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation. Hum Mol Genet (2004) 1.37
The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. Hum Mol Genet (2002) 1.36
AIP4/Itch regulates Notch receptor degradation in the absence of ligand. PLoS One (2008) 1.35
Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection. J Neurosci (2003) 1.28
T-cell-receptor- and B-cell-receptor-mediated activation of NF-kappaB in lymphocytes. Curr Opin Immunol (2004) 1.19
Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor. Immunity (2003) 1.18
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures. J Cell Biol (2014) 1.17
The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration. J Biol Chem (2004) 1.15
The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity. Proc Natl Acad Sci U S A (2008) 1.13
Post-translational modifications regulate distinct functions of CARMA1 and BCL10. Trends Immunol (2007) 1.11
The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains. J Biol Chem (2004) 1.11
Visualization of lymphatic vessels through NF-kappaB activity. Blood (2004) 1.10
NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein. PLoS Pathog (2009) 1.08
Toward an integrative view of Optineurin functions. Cell Cycle (2012) 1.04
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding. J Mol Biol (2009) 1.02
Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression. Mol Cell (2012) 1.02
Listeriolysin O secreted by Listeria monocytogenes induces NF-kappaB signalling by activating the IkappaB kinase complex. Mol Microbiol (2002) 1.01
IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival. Proc Natl Acad Sci U S A (2003) 0.95
Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization. J Biol Chem (2004) 0.95
The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation. J Biol Chem (2012) 0.94
Genomic expression patterns distinguish long-term from short-term glioblastoma survivors: a preliminary feasibility study. Genomics (2008) 0.93
IKK regulation and human genetics. Curr Top Microbiol Immunol (2011) 0.91
Sleep deprivation increases the activation of nuclear factor kappa B in lateral hypothalamic cells. Brain Res (2004) 0.90
Your diagnosis? Umbilical cord tumor. Eur J Pediatr (2006) 0.89
Liver x receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: a key role for lysophosphatidylcholine acyltransferase 3. Arterioscler Thromb Vasc Biol (2013) 0.89
Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals. J Cell Sci (2013) 0.88
The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathway. J Biol Chem (2011) 0.87
The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCtheta and ERK pathways. Blood (2007) 0.87
Combined deficiency in IkappaBalpha and IkappaBepsilon reveals a critical window of NF-kappaB activity in natural killer cell differentiation. Blood (2004) 0.85
Signal transduction: A regulator branches out. Nature (2003) 0.84
The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors. FASEB J (2013) 0.84
Asleep-awake-asleep craniotomy: a comparison with general anesthesia for resection of supratentorial tumors. J Clin Neurosci (2013) 0.82
Arachidonic acid differentially affects basal and lipopolysaccharide-induced sPLA(2)-IIA expression in alveolar macrophages through NF-kappaB and PPAR-gamma-dependent pathways. Mol Pharmacol (2002) 0.82
Optineurin: a new vision of cell division control. Cell Cycle (2012) 0.81
Isolation of nuclear proteins from flax (Linum usitatissimum L.) seed coats for gene expression regulation studies. BMC Res Notes (2012) 0.80
Podophyllotoxin and deoxypodophyllotoxin in Juniperus bermudiana and 12 other Juniperus species: optimization of extraction, method validation, and quantification. J Agric Food Chem (2011) 0.79
Pregnancy and acromegaly: a review. Pituitary (2012) 0.79
RelAp43, a member of the NF-κB family involved in innate immune response against Lyssavirus infection. PLoS Pathog (2012) 0.78
A glycosphingolipid binding domain controls trafficking and activity of the mammalian notch ligand delta-like 1. PLoS One (2013) 0.78
NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus. Cell Signal (2003) 0.78
Non-convulsive status epilepticus in the postanesthesia care unit following meningioma excision. Can J Anaesth (2011) 0.78
Allelic losses in oligodendroglial and oligodendroglioma-like neoplasms: analysis using microsatellite repeats and polymerase chain reaction. Arch Pathol Lab Med (2003) 0.77
Juvenile psammomatoid ossifying fibroma of the forehead, radical resection, and defect coverage with a hydroxyl-apatite composite-a case report. Eur J Pediatr Surg (2012) 0.77
Identification and characterization of cis-acting elements involved in the regulation of ABA- and/or GA-mediated LuPLR1 gene expression and lignan biosynthesis in flax (Linum usitatissimum L.) cell cultures. J Plant Physiol (2012) 0.76
Role of protein farnesylation events in the ABA-mediated regulation of the Pinoresinol-Lariciresinol Reductase 1 (LuPLR1) gene expression and lignan biosynthesis in flax (Linum usitatissimum L.). Plant Physiol Biochem (2013) 0.76
Abscisic acid regulates pinoresinol-lariciresinol reductase gene expression and secoisolariciresinol accumulation in developing flax (Linum usitatissimum L.) seeds. Planta (2011) 0.76
Correction: Optineurin Regulates the Interferon Response in a Cell Cycle-Dependent Manner. PLoS Pathog (2015) 0.75
Reply to 'Alice Dautry' profile. Nat Med (2007) 0.75
[Human pathologies associated with NF-kappaB defects]. J Soc Biol (2004) 0.75
Risk of thromboembolic events in patients with prolactinomas compared with patients with nonfunctional pituitary adenomas. Pituitary (2013) 0.75
Generation and characterization of mutant cell lines defective in gamma-secretase processing of Notch and amyloid precursor protein. J Biol Chem (2005) 0.75
[New Bcl10 regulation mechanisms: a step in the comprehension of what has occurred in MALT lymphomas?]. Med Sci (Paris) (2007) 0.75
[Regulation of NF-kappaB pathway in T lymphocytes]. Med Sci (Paris) (2007) 0.75