Published in Biochem Pharmacol on December 10, 2006
Relaxin and its role in the development and treatment of fibrosis. Transl Res (2009) 0.98
Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat. Reprod Biol Endocrinol (2007) 0.87
Relaxin decreases the severity of established hepatic fibrosis in mice. Liver Int (2013) 0.80
Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis. Ann N Y Acad Sci (2009) 0.79
Immunological response in alcoholic liver disease. World J Gastroenterol (2007) 0.78
Relaxin activates peroxisome proliferator-activated receptor γ (PPARγ) through a pathway involving PPARγ coactivator 1α (PGC1α). J Biol Chem (2014) 0.77
Anti-fibrotic actions of relaxin. Br J Pharmacol (2016) 0.76
Relaxin family peptide receptor 1 activation stimulates peroxisome proliferator-activated receptor gamma. Ann N Y Acad Sci (2009) 0.75
Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis. Arthritis Rheumatol (2015) 1.58
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway. J Hepatol (2006) 1.39
Desensitization of PKA-stimulated ciliary beat frequency in an ethanol-fed rat model of cigarette smoke exposure. Alcohol Clin Exp Res (2004) 1.24
An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures. Diabetes (2003) 1.21
A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes. J Nutr (2005) 1.20
Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells. Hepatology (2002) 1.19
Repetitive organic dust exposure in vitro impairs macrophage differentiation and function. J Allergy Clin Immunol (2008) 1.18
Inhibition of markers of hepatic stellate cell activation by the hormone relaxin. Biochem Pharmacol (2003) 1.18
Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells. J Hepatol (2005) 1.15
Betaine administration corrects ethanol-induced defective VLDL secretion. Mol Cell Biochem (2009) 1.12
Tacrolimus and sirolimus cause insulin resistance in normal sprague dawley rats. Transplantation (2006) 1.09
Smoke exposure exacerbates an ethanol-induced defect in mucociliary clearance of Streptococcus pneumoniae. Alcohol Clin Exp Res (2005) 1.06
Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats. J Nutr (2003) 1.06
Chronic ethanol consumption induces global hepatic protein hyperacetylation. Alcohol Clin Exp Res (2009) 1.05
Role of elevated S-adenosylhomocysteine in rat hepatocyte apoptosis: protection by betaine. Biochem Pharmacol (2005) 1.05
WIF-B cells as a model for alcohol-induced hepatocyte injury. Biochem Pharmacol (2004) 1.05
Hybrid malondialdehyde and acetaldehyde protein adducts form in the lungs of mice exposed to alcohol and cigarette smoke. Alcohol Clin Exp Res (2011) 1.05
Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells. Hepatology (2007) 1.04
Cirrhosis-induced defects in innate pulmonary defenses against Streptococcus pneumoniae. BMC Microbiol (2007) 1.04
Methionine synthase. a possible prime site of the ethanolic lesion in liver. Alcohol (2002) 1.02
Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. Hepatology (2008) 1.02
Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway. Alcohol Clin Exp Res (2006) 1.01
Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells. Alcohol Clin Exp Res (2004) 1.00
The effect of ethanol on asialoglycoprotein receptor-mediated phagocytosis of apoptotic cells by rat hepatocytes. Hepatology (2002) 0.97
Malondialdehyde-acetaldehyde-adducted protein inhalation causes lung injury. Alcohol (2011) 0.97
Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins. Mol Pharmacol (2005) 0.97
Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function. Hepatology (2008) 0.95
Malondialdehyde-acetaldehyde adducts decrease bronchial epithelial wound repair. Alcohol (2005) 0.95
Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells. Autophagy (2012) 0.94
Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity. J Hepatol (2007) 0.94
Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome. Int J Hepatol (2011) 0.93
Adduction of soluble proteins with malondialdehyde-acetaldehyde (MAA) induces antibody production and enhances T-cell proliferation. Alcohol Clin Exp Res (2002) 0.93
Malondialdehyde-acetaldehyde adduct is the dominant epitope after MDA modification of proteins in atherosclerosis. Free Radic Biol Med (2010) 0.92
Effect of chronic ethanol administration on the in vitro production of proinflammatory cytokines by rat Kupffer cells in the presence of apoptotic cells. Alcohol Clin Exp Res (2007) 0.92
Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells. Hepatology (2003) 0.92
Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells. Comp Hepatol (2004) 0.90
Alcoholic pancreatitis: lessons from the liver. World J Gastroenterol (2010) 0.90
Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells. World J Gastroenterol (2007) 0.90
Degradation of relaxin family peptides by insulin-degrading enzyme. Ann N Y Acad Sci (2009) 0.90
An in vitro method of alcoholic liver injury using precision-cut liver slices from rats. Biochem Pharmacol (2008) 0.89
Smoke exposure and ethanol ingestion modulate intrapulmonary polymorphonuclear leukocyte killing, but not recruitment or phagocytosis. Alcohol Clin Exp Res (2006) 0.89
Nitric oxide inhibits insulin-degrading enzyme activity and function through S-nitrosylation. Biochem Pharmacol (2008) 0.88
Influence of soil type and extraction conditions on perchlorate analysis by ion chromatography. Chemosphere (2006) 0.88
Transforming growth factor-beta induces contraction of activated hepatic stellate cells. J Hepatol (2004) 0.88
Autoimmune hepatitis induced by syngeneic liver cytosolic proteins biotransformed by alcohol metabolites. Alcohol Clin Exp Res (2010) 0.88
Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol. Biochem Pharmacol (2005) 0.88
T cell proliferative responses to malondialdehyde-acetaldehyde haptenated protein are scavenger receptor mediated. Int Immunopharmacol (2003) 0.87
Recent advances in alcohol-induced adduct formation. Alcohol Clin Exp Res (2005) 0.87
Impaired methylation as a novel mechanism for proteasome suppression in liver cells. Biochem Biophys Res Commun (2009) 0.87
Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction. Diabetes (2011) 0.87
Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells. World J Gastroenterol (2009) 0.87
Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption. Methods Mol Biol (2008) 0.87
Efficacy of liposome-encapsulated ciprofloxacin compared with ciprofloxacin and ceftriaxone in a rat model of pneumococcal pneumonia. J Antimicrob Chemother (2003) 0.86
Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells. Biochem Pharmacol (2002) 0.86
Neointimal hyperplasia and vascular endothelial growth factor expression are increased in normoglycemic, insulin resistant, obese fatty rats. Atherosclerosis (2005) 0.84
Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis. Am J Physiol Gastrointest Liver Physiol (2010) 0.84
A novel flow cytometric assay for measurement of in vivo pulmonary neutrophil phagocytosis. BMC Microbiol (2006) 0.84
Chronic ethanol treatment impairs Rac and Cdc42 activation in rat hepatocytes. Alcohol Clin Exp Res (2006) 0.84
Effects of a PPAR-gamma agonist, on growth factor and insulin stimulated endothelial cells. Vascul Pharmacol (2009) 0.83
Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells. Biochem Pharmacol (2009) 0.83
Hyperglycemia induced by tacrolimus and sirolimus is reversible in normal sprague-dawley rats. Endocrine (2010) 0.83
A flow cytometric assay to quantify in vivo bacterial uptake by alveolar macrophages. J Microbiol Methods (2010) 0.82
Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines. Chem Res Toxicol (2005) 0.82
Insulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stability. PLoS One (2010) 0.82
Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Front Biosci (2004) 0.82
Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism. Alcohol Clin Exp Res (2013) 0.81
Lipid droplet accumulation and impaired fat efflux in polarized hepatic cells: consequences of ethanol metabolism. Int J Hepatol (2012) 0.81
Lysine acetylation induced by chronic ethanol consumption impairs dynamin-mediated clathrin-coated vesicle release. Hepatology (2012) 0.80
The impact of ethanol and tobacco smoke on intranasal epithelium in the rat. Am J Rhinol (2003) 0.80
Metformin improves immunosuppressant induced hyperglycemia and exocrine apoptosis in rats. Transplantation (2013) 0.80
Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells. Biochem Pharmacol (2003) 0.80
Relaxin decreases the severity of established hepatic fibrosis in mice. Liver Int (2013) 0.80
Effect of cirrhosis on antibiotic efficacy in a rat model of pneumococcal pneumonia. Diagn Microbiol Infect Dis (2005) 0.79
Redox regulation of insulin degradation by insulin-degrading enzyme. PLoS One (2011) 0.79
Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis. Ann N Y Acad Sci (2009) 0.79
Susceptibility to T cell-mediated liver injury is enhanced in asialoglycoprotein receptor-deficient mice. Int Immunopharmacol (2013) 0.78
Hepatic microtubule acetylation and stability induced by chronic alcohol exposure impair nuclear translocation of STAT3 and STAT5B, but not Smad2/3. Am J Physiol Gastrointest Liver Physiol (2012) 0.78
Gene expression of vitamin D metabolic enzymes at baseline and in response to vitamin D treatment in thyroid cancer cell lines. Oncology (2012) 0.78
Alcohol, carcinoembryonic antigen processing and colorectal liver metastases. Adv Exp Med Biol (2015) 0.78
Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid. Biochem Pharmacol (2002) 0.77
Long-term effects of a PPAR-gamma agonist, pioglitazone, on neointimal hyperplasia and endothelial regrowth in insulin resistant rats. Vascul Pharmacol (2006) 0.77
Malondialdehyde-acetaldehyde-haptenated protein induces cell death by induction of necrosis and apoptosis in immune cells. Int Immunopharmacol (2002) 0.77
ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane. Arch Biochem Biophys (2002) 0.77
Biological activity of a fragment of insulin. Biochem Biophys Res Commun (2004) 0.77
Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde. Int Immunopharmacol (2008) 0.77
Alcohol consumption decreases rat hepatic creatine biosynthesis via altered guanidinoacetate methyltransferase activity. Alcohol Clin Exp Res (2013) 0.77
Relaxin receptor expression in hepatic stellate cells and in cirrhotic rat liver tissue. Ann N Y Acad Sci (2005) 0.77
Cyanamide potentiates the ethanol-induced impairment of receptor-mediated endocytosis in a recombinant hepatic cell line expressing alcohol dehydrogenase activity. Int J Hepatol (2012) 0.76
Tacrolimus and sirolimus induce reproductive abnormalities in female rats. Transplantation (2011) 0.76
In vitro exposure to malondialdehyde-acetaldehyde adducted protein inhibits cell proliferation and viability. Alcohol Clin Exp Res (2002) 0.76
Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells. BMC Anesthesiol (2005) 0.75
Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function. Mol Cell Biochem (2014) 0.75