Dean J Tuma

Author PubWeight™ 59.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis. Arthritis Rheumatol 2015 1.58
2 Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway. J Hepatol 2006 1.39
3 A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes. J Nutr 2005 1.20
4 Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells. Hepatology 2002 1.19
5 Inhibition of markers of hepatic stellate cell activation by the hormone relaxin. Biochem Pharmacol 2003 1.18
6 Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells. J Hepatol 2005 1.15
7 Betaine administration corrects ethanol-induced defective VLDL secretion. Mol Cell Biochem 2009 1.12
8 Relaxin receptors in hepatic stellate cells and cirrhotic liver. Biochem Pharmacol 2006 1.06
9 Betaine lowers elevated s-adenosylhomocysteine levels in hepatocytes from ethanol-fed rats. J Nutr 2003 1.06
10 Chronic ethanol consumption induces global hepatic protein hyperacetylation. Alcohol Clin Exp Res 2009 1.05
11 Role of elevated S-adenosylhomocysteine in rat hepatocyte apoptosis: protection by betaine. Biochem Pharmacol 2005 1.05
12 WIF-B cells as a model for alcohol-induced hepatocyte injury. Biochem Pharmacol 2004 1.05
13 Hybrid malondialdehyde and acetaldehyde protein adducts form in the lungs of mice exposed to alcohol and cigarette smoke. Alcohol Clin Exp Res 2011 1.05
14 Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells. Hepatology 2007 1.04
15 Methionine synthase. a possible prime site of the ethanolic lesion in liver. Alcohol 2002 1.02
16 Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. Hepatology 2008 1.02
17 Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway. Alcohol Clin Exp Res 2006 1.01
18 Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells. Alcohol Clin Exp Res 2004 1.00
19 The effect of ethanol on asialoglycoprotein receptor-mediated phagocytosis of apoptotic cells by rat hepatocytes. Hepatology 2002 0.97
20 Malondialdehyde-acetaldehyde-adducted protein inhalation causes lung injury. Alcohol 2011 0.97
21 Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins. Mol Pharmacol 2005 0.97
22 Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function. Hepatology 2008 0.95
23 Malondialdehyde-acetaldehyde adducts decrease bronchial epithelial wound repair. Alcohol 2005 0.95
24 Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells. Autophagy 2012 0.94
25 Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity. J Hepatol 2007 0.94
26 Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome. Int J Hepatol 2011 0.93
27 Adduction of soluble proteins with malondialdehyde-acetaldehyde (MAA) induces antibody production and enhances T-cell proliferation. Alcohol Clin Exp Res 2002 0.93
28 Malondialdehyde-acetaldehyde adduct is the dominant epitope after MDA modification of proteins in atherosclerosis. Free Radic Biol Med 2010 0.92
29 Effect of chronic ethanol administration on the in vitro production of proinflammatory cytokines by rat Kupffer cells in the presence of apoptotic cells. Alcohol Clin Exp Res 2007 0.92
30 Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells. Hepatology 2003 0.92
31 Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells. World J Gastroenterol 2007 0.90
32 Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells. Comp Hepatol 2004 0.90
33 An in vitro method of alcoholic liver injury using precision-cut liver slices from rats. Biochem Pharmacol 2008 0.89
34 Transforming growth factor-beta induces contraction of activated hepatic stellate cells. J Hepatol 2004 0.88
35 Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol. Biochem Pharmacol 2005 0.88
36 Autoimmune hepatitis induced by syngeneic liver cytosolic proteins biotransformed by alcohol metabolites. Alcohol Clin Exp Res 2010 0.88
37 T cell proliferative responses to malondialdehyde-acetaldehyde haptenated protein are scavenger receptor mediated. Int Immunopharmacol 2003 0.87
38 Recent advances in alcohol-induced adduct formation. Alcohol Clin Exp Res 2005 0.87
39 Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption. Methods Mol Biol 2008 0.87
40 Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells. World J Gastroenterol 2009 0.87
41 Impaired methylation as a novel mechanism for proteasome suppression in liver cells. Biochem Biophys Res Commun 2009 0.87
42 Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells. Biochem Pharmacol 2002 0.86
43 Chronic ethanol treatment impairs Rac and Cdc42 activation in rat hepatocytes. Alcohol Clin Exp Res 2006 0.84
44 Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis. Am J Physiol Gastrointest Liver Physiol 2010 0.84
45 Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells. Biochem Pharmacol 2009 0.83
46 Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines. Chem Res Toxicol 2005 0.82
47 Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Front Biosci 2004 0.82
48 Lipid droplet accumulation and impaired fat efflux in polarized hepatic cells: consequences of ethanol metabolism. Int J Hepatol 2012 0.81
49 Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism. Alcohol Clin Exp Res 2013 0.81
50 Relaxin decreases the severity of established hepatic fibrosis in mice. Liver Int 2013 0.80
51 Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells. Biochem Pharmacol 2003 0.80
52 Lysine acetylation induced by chronic ethanol consumption impairs dynamin-mediated clathrin-coated vesicle release. Hepatology 2012 0.80
53 Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis. Ann N Y Acad Sci 2009 0.79
54 Susceptibility to T cell-mediated liver injury is enhanced in asialoglycoprotein receptor-deficient mice. Int Immunopharmacol 2013 0.78
55 Hepatic microtubule acetylation and stability induced by chronic alcohol exposure impair nuclear translocation of STAT3 and STAT5B, but not Smad2/3. Am J Physiol Gastrointest Liver Physiol 2012 0.78
56 Alcohol, carcinoembryonic antigen processing and colorectal liver metastases. Adv Exp Med Biol 2015 0.78
57 Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde. Int Immunopharmacol 2008 0.77
58 Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid. Biochem Pharmacol 2002 0.77
59 Malondialdehyde-acetaldehyde-haptenated protein induces cell death by induction of necrosis and apoptosis in immune cells. Int Immunopharmacol 2002 0.77
60 ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane. Arch Biochem Biophys 2002 0.77
61 Alcohol consumption decreases rat hepatic creatine biosynthesis via altered guanidinoacetate methyltransferase activity. Alcohol Clin Exp Res 2013 0.77
62 Relaxin receptor expression in hepatic stellate cells and in cirrhotic rat liver tissue. Ann N Y Acad Sci 2005 0.77
63 Cyanamide potentiates the ethanol-induced impairment of receptor-mediated endocytosis in a recombinant hepatic cell line expressing alcohol dehydrogenase activity. Int J Hepatol 2012 0.76
64 In vitro exposure to malondialdehyde-acetaldehyde adducted protein inhibits cell proliferation and viability. Alcohol Clin Exp Res 2002 0.76
65 Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function. Mol Cell Biochem 2014 0.75
66 Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells. BMC Anesthesiol 2005 0.75