Serum biomarkers for delirium.

PubWeight™: 1.45‹?› | Rank: Top 5%

🔗 View Article (PMID 17234821)

Published in J Gerontol A Biol Sci Med Sci on December 01, 2006

Authors

Edward R Marcantonio1, James L Rudolph, Deborah Culley, Gregory Crosby, David Alsop, Sharon K Inouye

Author Affiliations

1: Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02446, USA. emarcant@bidmc.harvard.edu

Articles citing this

Delirium in elderly people. Lancet (2013) 6.15

Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods. J Am Med Dir Assoc (2012) 1.73

Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses. J Psychosom Res (2008) 1.72

Risk factors for delirium in intensive care patients: a prospective cohort study. Crit Care (2009) 1.67

Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci (2008) 1.61

Cerebral perfusion in sepsis-associated delirium. Crit Care (2008) 1.33

Chemokines are associated with delirium after cardiac surgery. J Gerontol A Biol Sci Med Sci (2008) 1.26

Elucidating the pathophysiology of delirium and the interrelationship of delirium and dementia. J Gerontol A Biol Sci Med Sci (2006) 1.26

Aging, brain disease, and reserve: implications for delirium. Am J Geriatr Psychiatry (2010) 1.20

Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing delirium in inflamed and noninflamed patients. Crit Care (2011) 1.19

Neuroinflammation in delirium: a postmortem case-control study. Rejuvenation Res (2011) 1.11

Associations of markers of inflammation and coagulation with delirium during critical illness. Intensive Care Med (2012) 1.02

Improving delirium care in the intensive care unit: the design of a pragmatic study. Trials (2011) 0.96

Biomarkers for delirium--a review. J Am Geriatr Soc (2011) 0.91

Low tryptophan levels are associated with postoperative delirium in the elderly. Am J Surg (2008) 0.89

Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. Front Aging Neurosci (2014) 0.86

Tryptophan supplementation and postoperative delirium--a randomized controlled trial. J Am Geriatr Soc (2014) 0.84

Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. J Gerontol A Biol Sci Med Sci (2015) 0.84

Perioperative delirium and its relationship to dementia. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.83

Predicting, preventing, and identifying delirium after cardiac surgery. Perioper Med (Lond) (2016) 0.81

The Johns Hopkins Delirium Consortium: a model for collaborating across disciplines and departments for delirium prevention and treatment. J Am Geriatr Soc (2011) 0.78

Delirium-biomarkers and genetic variance. Front Pharmacol (2014) 0.76

Urinary protein profiling in hyperactive delirium and non-delirium cardiac surgery ICU patients. Proteome Sci (2011) 0.76

Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients. Psychiatry Investig (2016) 0.75

Assessment and Management of Delirium in Older Adults in the Emergency Department: Literature Review to Inform Development of a Novel Clinical Protocol. Adv Emerg Nurs J (2015) 0.75

Cortisol is an associated-risk factor of brain dysfunction in patients with severe sepsis and septic shock. Biomed Res Int (2014) 0.75

Is postoperative delirium a relevant outcome? J Anesth (2015) 0.75

Moderate dose melatonin for the abatement and treatment of delirium in elderly general medical inpatients: study protocol of a placebo controlled, randomised, double blind trial. BMC Geriatr (2016) 0.75

Articles by these authors

Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA (2004) 11.27

Cognitive trajectories after postoperative delirium. N Engl J Med (2012) 4.69

One-year health care costs associated with delirium in the elderly population. Arch Intern Med (2008) 3.82

The Confusion Assessment Method: a systematic review of current usage. J Am Geriatr Soc (2008) 3.51

Delirium superimposed on dementia: a systematic review. J Am Geriatr Soc (2002) 3.44

3D-CAM: derivation and validation of a 3-minute diagnostic interview for CAM-defined delirium: a cross-sectional diagnostic test study. Ann Intern Med (2014) 3.34

Delirium and Long-term Cognitive Trajectory Among Persons With Dementia. Arch Intern Med (2012) 3.27

Characteristics associated with delirium in older patients in a medical intensive care unit. Arch Intern Med (2007) 3.16

Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties. Ann Surg (2013) 3.15

Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation (2008) 3.06

Delirium in older people. BMJ (2007) 2.77

The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg (2003) 2.69

Hospital at home: feasibility and outcomes of a program to provide hospital-level care at home for acutely ill older patients. Ann Intern Med (2005) 2.58

The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol (2008) 2.54

Delirium in the intensive care unit: occurrence and clinical course in older patients. J Am Geriatr Soc (2003) 2.53

An fMRI study of facial emotion processing in patients with schizophrenia. Am J Psychiatry (2002) 2.50

Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med (2009) 2.47

Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats. Anesthesiology (2004) 2.45

Delirium in elderly adults: diagnosis, prevention and treatment. Nat Rev Neurol (2009) 2.44

The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation. J Neurosci (2007) 2.42

Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology (2011) 2.41

The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology (2006) 2.26

Effects of anti-viral therapy and HCV clearance on cerebral metabolism and cognition. J Hepatol (2011) 2.20

The overlap syndrome of depression and delirium in older hospitalized patients. J Am Geriatr Soc (2009) 2.12

Prevalence and outcomes of low mobility in hospitalized older patients. J Am Geriatr Soc (2004) 2.08

Translating research into practice: speeding the adoption of innovative health care programs. Issue Brief (Commonw Fund) (2004) 2.03

Intraoperative cerebral high-intensity transient signals and postoperative cognitive function: a systematic review. Am J Surg (2008) 1.92

General anesthesia--minding the mind during surgery. N Engl J Med (2011) 1.89

A research algorithm to improve detection of delirium in the intensive care unit. Crit Care (2006) 1.89

Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci (2006) 1.83

Delirium: an independent predictor of functional decline after cardiac surgery. J Am Geriatr Soc (2010) 1.82

Modified hospital elder life program: effects on abdominal surgery patients. J Am Coll Surg (2011) 1.79

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol (2012) 1.76

Brain activation during facial emotion processing. Neuroimage (2002) 1.76

Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods. J Am Med Dir Assoc (2012) 1.73

Persistent delirium predicts greater mortality. J Am Geriatr Soc (2009) 1.66

Short-term outcomes in older intensive care unit patients with dementia. Crit Care Med (2005) 1.65

The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β. Neurobiol Aging (2010) 1.62

Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci (2008) 1.61

Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg (2004) 1.60

White matter hyperintensities and dynamics of postural control. Magn Reson Imaging (2009) 1.60

Identifying indicators of important diagnostic features of delirium. J Am Geriatr Soc (2012) 1.57

Tone deafness: a new disconnection syndrome? J Neurosci (2009) 1.56

The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol (2009) 1.56

Consequences of preventing delirium in hospitalized older adults on nursing home costs. J Am Geriatr Soc (2005) 1.52

Adults and children processing music: an fMRI study. Neuroimage (2005) 1.51

Premature death associated with delirium at 1-year follow-up. Arch Intern Med (2005) 1.48

Older adults discharged from the hospital with delirium: 1-year outcomes. J Am Geriatr Soc (2006) 1.48

Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity. Anesthesiology (2015) 1.48

Diagnosing delirium in older hospitalized adults with dementia: adapting the confusion assessment method to international classification of diseases, tenth revision, diagnostic criteria. J Am Geriatr Soc (2012) 1.48

Serial administration of a modified Richmond Agitation and Sedation Scale for delirium screening. J Hosp Med (2011) 1.47

Replicating the Hospital Elder Life Program in a community hospital and demonstrating effectiveness using quality improvement methodology. J Am Geriatr Soc (2006) 1.46

Telephone interview for cognitive status: Creating a crosswalk with the Mini-Mental State Examination. Alzheimers Dement (2009) 1.45

Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44

Detection of delirium in the intensive care unit: comparison of confusion assessment method for the intensive care unit with confusion assessment method ratings. J Am Geriatr Soc (2005) 1.41

Neural basis for sentence comprehension: grammatical and short-term memory components. Hum Brain Mapp (2002) 1.40

Hospitalization in community-dwelling persons with Alzheimer's disease: frequency and causes. J Am Geriatr Soc (2010) 1.39

Delirium superimposed on dementia is associated with prolonged length of stay and poor outcomes in hospitalized older adults. J Hosp Med (2013) 1.39

Learning from the closure of clinical programs: a case series from the Hospital Elder Life Program. J Am Geriatr Soc (2013) 1.39

Suburban leptospirosis: atypical lymphocytosis and gamma-delta T cell response. Clin Infect Dis (2006) 1.39

Delirium superimposed on dementia in a community-dwelling managed care population: a 3-year retrospective study of occurrence, costs, and utilization. J Gerontol A Biol Sci Med Sci (2005) 1.39

Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patients. J Am Geriatr Soc (2007) 1.39

A tale of two methods: chart and interview methods for identifying delirium. J Am Geriatr Soc (2014) 1.37

Adverse outcomes after hospitalization and delirium in persons with Alzheimer disease. Ann Intern Med (2012) 1.33

Underrecognition of preexisting cognitive impairment by physicians in older ICU patients. Chest (2003) 1.33

Screening for preexisting cognitive impairment in older intensive care unit patients: use of proxy assessment. J Am Geriatr Soc (2003) 1.32

Cerebral perfusion changes in older delirious patients using 99mTc HMPAO SPECT. J Gerontol A Biol Sci Med Sci (2006) 1.32

Development of a unidimensional composite measure of neuropsychological functioning in older cardiac surgery patients with good measurement precision. J Clin Exp Neuropsychol (2010) 1.31

The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem (2008) 1.31

Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma (2014) 1.30

Sustainability and scalability of the hospital elder life program at a community hospital. J Am Geriatr Soc (2011) 1.29

The importance of delirium: economic and societal costs. J Am Geriatr Soc (2011) 1.27

Independent vascular and cognitive risk factors for postoperative delirium. Am J Med (2007) 1.27

Age-related changes in working memory during sentence comprehension: an fMRI study. Neuroimage (2002) 1.24

Thickness of the human cerebral cortex is associated with metrics of cerebrovascular health in a normative sample of community dwelling older adults. Neuroimage (2010) 1.23

Development and validation of a risk-adjustment index for older patients: the high-risk diagnoses for the elderly scale. J Am Geriatr Soc (2002) 1.23

Independent association between preoperative cognitive status and discharge location after cardiac surgery. Am J Crit Care (2011) 1.23

Inter-individual variation in blood pressure is associated with regional white matter integrity in generally healthy older adults. Neuroimage (2011) 1.22

Aging, brain disease, and reserve: implications for delirium. Am J Geriatr Psychiatry (2010) 1.20

Calibration and validation of an innovative approach for estimating general cognitive performance. Neuroepidemiology (2014) 1.19

Adhesion molecules, altered vasoreactivity, and brain atrophy in type 2 diabetes. Diabetes Care (2011) 1.18

Career National Institutes of Health funding and scholarship of chairpersons of academic departments of anesthesiology and surgery. Anesthesiology (2007) 1.18

Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice. Anesthesiology (2013) 1.16

Spatial memory performance 2 weeks after general anesthesia in adult rats. Anesth Analg (2005) 1.16

Prevalence and correlates of perceived societal racism in older African-American adults with type 2 diabetes mellitus. J Am Geriatr Soc (2005) 1.16

After adoption: sustaining the innovation. A case study of disseminating the hospital elder life program. J Am Geriatr Soc (2005) 1.14

Parkinson's disease spatial covariance pattern: noninvasive quantification with perfusion MRI. J Cereb Blood Flow Metab (2010) 1.14

Maximizing clinical research participation in vulnerable older persons: identification of barriers and motivators. J Am Geriatr Soc (2008) 1.13

Phenomenological subtypes of delirium in older persons: patterns, prevalence, and prognosis. Psychosomatics (2009) 1.13

Translating research into clinical practice: making change happen. J Am Geriatr Soc (2004) 1.12

Recognizing delirium superimposed on dementia: assessing nurses' knowledge using case vignettes. J Gerontol Nurs (2007) 1.12

C-Reactive protein and inflammatory response associated to neurocognitive decline following cardiac surgery. Surgery (2006) 1.11

Aging, antiretrovirals, and adherence: a meta analysis of adherence among older HIV-infected individuals. Drugs Aging (2013) 1.11

Dissociable networks for the expectancy and perception of emotional stimuli in the human brain. Neuroimage (2005) 1.10

Processed electroencephalogram and depth of anesthesia: window to nowhere or into the brain? Anesthesiology (2012) 1.10