Published in Genetics on January 21, 2007
A critical three-way junction is conserved in budding yeast and vertebrate telomerase RNAs. Nucleic Acids Res (2007) 1.15
End joining at Caenorhabditis elegans telomeres. Genetics (2008) 1.01
Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype. Mol Cell Biol (2008) 0.90
RNA recognition by the DNA end-binding Ku heterodimer. RNA (2013) 0.83
Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells. Eukaryot Cell (2010) 0.79
The 5' arm of Kluyveromyces lactis telomerase RNA is critical for telomerase function. Mol Cell Biol (2008) 0.79
Mating type influences chromosome loss and replicative senescence in telomerase-deficient budding yeast by Dnl4-dependent telomere fusion. Mol Microbiol (2008) 0.78
Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification. Mol Cell Biol (2012) 0.77
The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination. PLoS One (2011) 0.76
"Poisoning" yeast telomeres distinguishes between redundant telomere capping pathways. Chromosoma (2012) 0.75
5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol (1987) 17.67
The Stability of Broken Ends of Chromosomes in Zea Mays. Genetics (1941) 16.95
TRF2 protects human telomeres from end-to-end fusions. Cell (1998) 10.13
A mutant with a defect in telomere elongation leads to senescence in yeast. Cell (1989) 8.69
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33
An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell (1993) 6.89
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J (1998) 5.79
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nat Genet (1997) 4.95
Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature (1997) 4.49
Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature (1997) 4.34
Runaway telomere elongation caused by telomerase RNA gene mutations. Nature (1995) 4.34
RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell (1990) 4.25
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2. Curr Biol (2002) 3.95
Yeast Ku as a regulator of chromosomal DNA end structure. Science (1998) 3.86
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell (1993) 3.77
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.57
Nonhomologous end joining in yeast. Annu Rev Genet (2005) 3.32
Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J (1997) 3.29
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev (2003) 3.21
Telomeres and telomerase. Philos Trans R Soc Lond B Biol Sci (2004) 3.13
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev (2002) 3.05
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang. EMBO Rep (2000) 3.00
Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol Cell (2003) 2.78
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev (1996) 2.76
Circular chromosome formation in a fission yeast mutant defective in two ATM homologues. Nat Genet (1998) 2.71
A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev (1997) 2.61
Two modes of survival of fission yeast without telomerase. Science (1998) 2.57
The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities. Curr Biol (1998) 2.57
NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42
Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev (2000) 2.38
Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol (2002) 2.35
Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.29
DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining. Nucleic Acids Res (2000) 2.29
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature (1996) 2.24
Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase. Proc Natl Acad Sci U S A (1996) 2.22
The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nat Genet (2001) 2.19
The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres. Curr Biol (2001) 2.16
A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae. Science (2001) 2.16
Ku, a DNA repair protein with multiple cellular functions? Mutat Res (1999) 2.16
Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr Biol (1999) 2.11
Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae. Genes Cells (1997) 2.04
Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J (1998) 2.03
Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle. Genes Dev (2004) 1.98
The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-to-end fusions. Mol Cell (2001) 1.95
NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev (2001) 1.93
Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol (2001) 1.91
The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics (2000) 1.89
Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J (2005) 1.87
Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1. J Biol Chem (2006) 1.79
Yeast cell-type regulation of DNA repair. Nature (1999) 1.76
Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing. Mol Cell Biol (2002) 1.69
Ku: a multifunctional protein involved in telomere maintenance. DNA Repair (Amst) (2005) 1.68
A novel pseudoknot element is essential for the action of a yeast telomerase. Genes Dev (2003) 1.55
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Curr Biol (2000) 1.51
A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics (2002) 1.49
Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment. Mol Cell Biol (2000) 1.48
Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells. Genetics (2004) 1.43
Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis. Proc Natl Acad Sci U S A (2003) 1.42
Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc Natl Acad Sci U S A (2003) 1.37
Short telomeres in yeast are highly recombinogenic. Mol Cell (2001) 1.31
The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol (2003) 1.28
NEJ1 prevents NHEJ-dependent telomere fusions in yeast without telomerase. Mol Cell (2003) 1.17
sir2 mutants of Kluyveromyces lactis are hypersensitive to DNA-targeting drugs. Mol Cell Biol (1994) 1.15
Telomere fusions caused by mutating the terminal region of telomeric DNA. Proc Natl Acad Sci U S A (2000) 1.12
A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast. Mol Cell Biol (2005) 1.03
Theme and variation among silencing proteins in Saccharomyces cerevisiae and Kluyveromyces lactis. Genetics (1998) 0.97
Which end: dissecting Ku's function at telomeres and double-strand breaks. Genes Dev (2003) 0.97
Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast. J Biol Chem (2002) 0.97
Genome wide distribution of illegitimate recombination events in Kluyveromyces lactis. Nucleic Acids Res (2006) 0.94
Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres. Eukaryot Cell (2004) 0.94
Characterization of Kluyveromyces lactis subtelomeric sequences including a distal element with strong purine/pyrimidine strand bias. Yeast (2004) 0.82
Screening for telomeric recombination in wild-type Kluyveromyces lactis. FEMS Yeast Res (2006) 0.78
A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A (2004) 3.21
Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China. Ann Occup Hyg (2004) 1.44
Recombinational telomere elongation promoted by DNA circles. Mol Cell Biol (2002) 1.43
Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. Mol Cell Biol (2007) 1.20
Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther (2009) 1.14
Alpha3, a transposable element that promotes host sexual reproduction. Genes Dev (2009) 1.12
Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles. Mol Cell Biol (2005) 1.03
A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast. Mol Cell Biol (2005) 1.03
Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. PLoS Genet (2011) 1.02
Telomerase core components protect Candida telomeres from aberrant overhang accumulation. Proc Natl Acad Sci U S A (2007) 1.01
Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis. Proc Natl Acad Sci U S A (2005) 1.01
Alternatives to telomerase: keeping linear chromosomes via telomeric circles. FEBS Lett (2004) 1.00
Factors influencing the recombinational expansion and spread of telomeric tandem arrays in Kluyveromyces lactis. Eukaryot Cell (2003) 0.98
Genome wide distribution of illegitimate recombination events in Kluyveromyces lactis. Nucleic Acids Res (2006) 0.94
Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres. Eukaryot Cell (2004) 0.94
Functional diversity of silencers in budding yeasts. Eukaryot Cell (2002) 0.93
Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution. Genome Biol (2014) 0.92
Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype. Mol Cell Biol (2008) 0.90
RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains. Mol Cells (2005) 0.87
Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism. Proc Natl Acad Sci U S A (2009) 0.85
Template requirements for telomerase translocation in Kluyveromyces lactis. Mol Cell Biol (2004) 0.84
Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis. Mol Biol Rep (2005) 0.82
Characterization of Kluyveromyces lactis subtelomeric sequences including a distal element with strong purine/pyrimidine strand bias. Yeast (2004) 0.82
Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination. Nucleic Acids Res (2009) 0.81
Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity. Eukaryot Cell (2011) 0.79
Recombination can cause telomere elongations as well as truncations deep within telomeres in wild-type Kluyveromyces lactis cells. Eukaryot Cell (2010) 0.79
Evidence for an additional base-pairing element between the telomeric repeat and the telomerase RNA template in Kluyveromyces lactis and other yeasts. Mol Cell Biol (2009) 0.79
Screening for telomeric recombination in wild-type Kluyveromyces lactis. FEMS Yeast Res (2006) 0.78
Tungsten carbide-nitride on graphene nanoplatelets as a durable hydrogen evolution electrocatalyst. ChemSusChem (2014) 0.78
Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification. Mol Cell Biol (2012) 0.77
Adsorption and protection of plasmid DNA on mesoporous silica nanoparticles modified with various amounts of organosilane. J Colloid Interface Sci (2011) 0.77
New potential biologically active compounds: design and an efficient synthesis of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-diones under microwave irradiation. Bioorg Med Chem Lett (2006) 0.77
A catalytic and non-catalytic role for the Yen1 nuclease in maintaining genome integrity in Kluyveromyces lactis. DNA Repair (Amst) (2012) 0.76
Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin. J Clin Invest (2016) 0.76
Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance. Eukaryot Cell (2012) 0.75
Poly[diaqua-(μ(3)-8-oxidoquinoline-5-sulfonato-κN,O:O:O)nickel(II)]. Acta Crystallogr Sect E Struct Rep Online (2009) 0.75
Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling. PLoS Genet (2012) 0.75
Brønsted guanidine acid-base ionic liquids: novel reaction media for the palladium-catalyzed Heck reaction. Org Lett (2006) 0.75
Stem cells, neural progenitors, and engineered stem cells. Methods Mol Biol (2015) 0.75
[Relationship between letrozole administration during the luteal phase after oocyte retrieval and the early-stage ovarian hyperstimulation syndrome oocurrence]. Zhonghua Fu Chan Ke Za Zhi (2014) 0.75
Sc₂(pydc)₂ unit based 1D, 2D and 3D metal-organic frameworks as heterogeneous Lewis acid catalysts for cyanosilylation. Dalton Trans (2015) 0.75
New potential inhibitors of cyclin-dependent kinase 4: design and synthesis of pyrido[2,3-d]pyrimidine derivatives under microwave irradiation. Bioorg Med Chem Lett (2006) 0.75
Indium metal-organic frameworks as high-performance heterogeneous catalysts for the synthesis of amino acid derivatives. Inorg Chem (2014) 0.75
Is There a Relationship Between Patient-Reported Satisfaction and Persistence on Overactive Bladder Syndrome Pharmacotherapy? Female Pelvic Med Reconstr Surg (2017) 0.75