TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 17239439)

Published in Mol Immunol on January 18, 2007

Authors

Michael Frink1, Ya-Ching Hsieh, Bjoern M Thobe, Mashkoor A Choudhry, Martin G Schwacha, Kirby I Bland, Irshad H Chaudry

Author Affiliations

1: Center for Surgical Research and Department of Surgery, University of Alabama at Birmingham, 1670 University Boulevard, Birmingham, AL 35294, USA.

Articles citing this

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A (2007) 3.91

Linking oxidative stress to inflammation: Toll-like receptors. Free Radic Biol Med (2010) 1.85

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol (2008) 1.58

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology (2009) 1.21

Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion. Shock (2009) 1.17

Trauma equals danger--damage control by the immune system. J Leukoc Biol (2012) 1.15

Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations. Mol Med (2008) 1.11

Decreased pulmonary inflammation following ethanol and burn injury in mice deficient in TLR4 but not TLR2 signaling. Alcohol Clin Exp Res (2010) 1.10

Activation of endoplasmic reticulum stress response following trauma-hemorrhage. Biochim Biophys Acta (2008) 1.02

Prenatal arsenic exposure alters gene expression in the adult liver to a proinflammatory state contributing to accelerated atherosclerosis. PLoS One (2012) 1.01

Toll-like receptor-4 mediates intestinal barrier breakdown after thermal injury. Surg Infect (Larchmt) (2010) 0.95

Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression. Am J Pathol (2009) 0.89

17 Beta-estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage. Mol Immunol (2007) 0.84

The level of hypotension during hemorrhagic shock is a major determinant of the post-resuscitation systemic inflammatory response: an experimental study. BMC Physiol (2008) 0.83

Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation. J Immunol (2009) 0.81

Trauma-hemorrhage and hypoxia differentially influence kupffer cell phagocytic capacity: role of hypoxia-inducible-factor-1alpha and phosphoinositide 3-kinase/Akt activation. Ann Surg (2009) 0.81

TIFA upregulation after hypoxia-reoxygenation is TLR4- and MyD88-dependent and associated with HMGB1 upregulation and release. Free Radic Biol Med (2013) 0.81

Induction of acute lung inflammation in mice with hemorrhagic shock and resuscitation: role of HMGB1. J Inflamm (Lond) (2014) 0.81

Macrophage-produced IL-12p70 mediates hemorrhage-induced damage in a complement-dependent manner. Shock (2011) 0.80

Preservation of hepatic blood flow by direct peritoneal resuscitation improves survival and prevents hepatic inflammation following hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol (2012) 0.78

Rosiglitazone protects against severe hemorrhagic shock-induced organ damage in rats. Med Sci Monit (2011) 0.77

Heavy ethanol intoxication increases proinflammatory cytokines and aggravates hemorrhagic shock-induced organ damage in rats. Mediators Inflamm (2013) 0.76

Serum diamine oxidase as a hemorrhagic shock biomarker in a rabbit model. PLoS One (2014) 0.75

TLR2 Regulates Complement-Mediated Inflammation Induced by Blood Loss During Hemorrhage. Shock (2016) 0.75

Estradiol's salutary effects on keratinocytes following trauma-hemorrhage are mediated by estrogen receptor (ER)-alpha and ER-beta. Mol Med (2008) 0.75

Articles by these authors

Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol (2002) 6.51

Cecal ligation and puncture. Shock (2005) 3.93

Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol (2002) 3.65

The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol (2003) 3.02

Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer. Lancet (2002) 2.83

Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual. Surg Clin North Am (2003) 2.82

Abandon the mouse research ship? Not just yet! Shock (2014) 2.60

Acute coagulopathy of trauma in the rat. Shock (2013) 2.08

Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clin Cancer Res (2004) 2.02

Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol (2008) 1.76

Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities. Shock (2013) 1.74

Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1. Am J Physiol Regul Integr Comp Physiol (2008) 1.61

Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis. Crit Care Med (2002) 1.60

Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Acad Emerg Med (2002) 1.57

Influence of sex and age on mods and cytokines after multiple injuries. Shock (2007) 1.56

High-frequency percussive ventilation and low tidal volume ventilation in burns: a randomized controlled trial. Crit Care Med (2010) 1.53

Mechanism of salutary effects of estrogen on cardiac function following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. Crit Care Med (2009) 1.52

Bench-to-bedside review: latest results in hemorrhagic shock. Crit Care (2008) 1.47

Detection of human cytomegalovirus in normal and neoplastic breast epithelium. Herpesviridae (2010) 1.40

Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury. Physiol Genomics (2005) 1.40

Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity. J Leukoc Biol (2003) 1.39

Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg (2002) 1.39

Factors associated with local recurrence after skin-sparing mastectomy and immediate breast reconstruction for invasive breast cancer. Ann Surg (2002) 1.38

Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. Am J Physiol Heart Circ Physiol (2008) 1.35

Gender differences in acute response to trauma-hemorrhage. Shock (2005) 1.34

Age-related gender differential in outcome after blunt or penetrating trauma. Shock (2003) 1.31

Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice. Physiol Genomics (2007) 1.30

Gender and susceptibility to sepsis following trauma. Endocr Metab Immune Disord Drug Targets (2006) 1.28

Treatment trends in early-stage invasive lobular carcinoma: a report from the National Cancer Data Base. Ann Surg (2005) 1.28

Preoperative radiation therapy with selective dose escalation to the margin at risk for retroperitoneal sarcoma. Cancer (2006) 1.27

The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage. J Cell Physiol (2007) 1.23

Sex differences in mortality after burn injury: results of analysis of the National Burn Repository of the American Burn Association. J Burn Care Res (2006) 1.23

Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage. Am J Pathol (2006) 1.22

Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1. Ann Surg (2002) 1.22

Gender differences in mortality following burn injury. Shock (2002) 1.19

Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers. Carcinogenesis (2005) 1.19

The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage. Shock (2009) 1.19

Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury. Cell Immunol (2002) 1.18

Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. Cancer Lett (2009) 1.18

When apoptosis meets autophagy: deciding cell fate after trauma and sepsis. Trends Mol Med (2009) 1.17

The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury. J Leukoc Biol (2004) 1.17

Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. Diabetes (2003) 1.17

Trauma and immune response--effect of gender differences. Injury (2007) 1.17

Acute alcohol intoxication potentiates neutrophil-mediated intestinal tissue damage after burn injury. Shock (2008) 1.17

The role of MIP-1 alpha in the development of systemic inflammatory response and organ injury following trauma hemorrhage. J Immunol (2008) 1.17

Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage. J Leukoc Biol (2006) 1.16

G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage. Am J Pathol (2007) 1.16

Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice. J Immunol (2006) 1.15

Hemorrhage induces the rapid development of hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol (2002) 1.13

Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats. Am J Physiol Lung Cell Mol Physiol (2007) 1.13

Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage. J Mol Cell Cardiol (2006) 1.12

Complete induction of autophagy is essential for cardioprotection in sepsis. Ann Surg (2011) 1.12

Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations. Mol Med (2008) 1.11

Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches. Langenbecks Arch Surg (2005) 1.11

Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse. Shock (2002) 1.11

The association between gender and mortality among trauma patients as modified by age. J Trauma (2003) 1.11

Mechanism of cardioprotection following trauma-hemorrhagic shock by a selective estrogen receptor-beta agonist: up-regulation of cardiac heat shock factor-1 and heat shock proteins. J Mol Cell Cardiol (2005) 1.10

Heme oxygenase-1 protects against neutrophil-mediated intestinal damage by down-regulation of neutrophil p47phox and p67phox activity and O2- production in a two-hit model of alcohol intoxication and burn injury. J Immunol (2008) 1.10

Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury. J Leukoc Biol (2005) 1.10