Regional variation in oral mucosal drug absorption: permeability and degree of keratinization in hamster oral cavity.

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🔗 View Article (PMID 1724562)

Published in Pharm Res on October 01, 1991

Authors

Y Kurosaki1, T Takatori, H Nishimura, T Nakayama, T Kimura

Author Affiliations

1: Faculty of Pharmaceutical Sciences, Okayama University, Japan.

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Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions. DNA Res (1996) 28.37

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol (2001) 12.26

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. Nature (1997) 7.69

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol (1996) 6.79

Laparoscopic cholecystectomy using fine-caliber instruments. Surg Endosc (1998) 6.36

Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med (2000) 6.15

Quantized conductance atomic switch. Nature (2005) 5.56

Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti. DNA Res (2000) 4.94

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science (1994) 4.50

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell (1993) 4.46

Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120. DNA Res (2001) 4.27

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci (2001) 4.02

The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. Nature (1999) 3.65

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Cell (1994) 3.56

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med (2001) 3.56

Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med (1997) 3.35

Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn (1999) 3.33

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci U S A (2001) 3.32

Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms. J Biol Chem (1991) 3.01

Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs. Proc Natl Acad Sci U S A (1987) 3.00

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. Proc Natl Acad Sci U S A (1998) 2.96

Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population. Gastroenterology (1992) 2.83

Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature (1997) 2.72

Antiproteinuric effect of the calcium channel blocker cilnidipine added to renin-angiotensin inhibition in hypertensive patients with chronic renal disease. Kidney Int (2007) 2.61

Sleep patterns and total mortality: a 12-year follow-up study in Japan. J Epidemiol (2000) 2.49

High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan. Gut (1999) 2.46

Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage phiPVL carrying Panton-Valentine leukocidin genes. Gene (1998) 2.43

Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene (2006) 2.42

A protein that binds to a cis-acting element of wheat histone genes has a leucine zipper motif. Science (1989) 2.42

Development of a simple and highly sensitive enzyme immunoassay for hepatitis C virus core antigen. J Clin Microbiol (1999) 2.41

Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. J Biol Chem (1993) 2.41

alpha -galactosylceramide-activated Valpha 14 natural killer T cells mediate protection against murine malaria. Proc Natl Acad Sci U S A (2000) 2.30

Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis. Nucleic Acids Res (2001) 2.28

Percutaneous transhepatic drainage of the biliary tract: technique and results in 104 cases. Gastroenterology (1978) 2.27

Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis. J Exp Med (2000) 2.25

Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation. Circ Res (2001) 2.25

Increased MR signal intensity due to cervical myelopathy. Analysis of 29 surgical cases. J Neurosurg (1991) 2.22

Normal and abnormal development of human embryos: first report of the analysis of 1,213 intact embryos. Teratology (1968) 2.20

Electrostatic mechanism of chromatin folding. J Mol Biol (1990) 2.18

Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17

Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation (1986) 2.17

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Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck. EMBO J (1992) 2.12

Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05

Pyridonecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent. J Med Chem (1984) 2.03

Restenosis after percutaneous transluminal coronary angioplasty: pathologic observations in 20 patients. J Am Coll Cardiol (1991) 2.03

Comparison of some pharmacokinetic parameters of 5 angiotensin-converting enzyme inhibitors in normal beagles. J Vet Intern Med (1998) 2.01

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Chromogenic substrates for horseshoe crab clotting enzyme. Its application for the assay of bacterial endotoxins. Haemostasis (1978) 1.96

T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice. Nat Med (1997) 1.94

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Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. Nat Genet (2000) 1.92

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Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma; correlation with clinicopathological factors. J Clin Pathol (2005) 1.90

Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. J Clin Invest (1998) 1.90

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Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest (1988) 1.89

Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells. J Exp Med (1999) 1.88

Atherosclerotic coronary lesions with inadequate compensatory enlargement have smaller plaque and vessel volumes: observations with three dimensional intravascular ultrasound in vivo. Heart (1998) 1.87

Human B cell, T cell and null cell leukaemic cell lines derived from acute lymphoblastic leukaemias. Nature (1977) 1.83

Bacterial oxidation of polyethylene glycol. Appl Environ Microbiol (1978) 1.80

Nuclear protein(s) binding to the conserved DNA hexameric sequence postulated to regulate transcription of wheat histone genes. FEBS Lett (1987) 1.79

Seven-color fluorescence imaging of tissue samples based on Fourier spectroscopy and singular value decomposition. J Histochem Cytochem (2000) 1.79

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Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia. Blood (1997) 1.72

A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis. Eur Respir J (2010) 1.72

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Resting K conductances in pacemaker and non-pacemaker heart cells of the rabbit. Jpn J Physiol (1984) 1.69

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Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1(IX) collagen chains with a central deletion. Proc Natl Acad Sci U S A (1993) 1.66

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Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin. J Biol Chem (1996) 1.65

Incidence of adverse reactions associated with acupuncture. J Altern Complement Med (2000) 1.65

A functional rhodopsin-green fluorescent protein fusion protein localizes correctly in transgenic Xenopus laevis retinal rods and is expressed in a time-dependent pattern. J Biol Chem (2001) 1.64

Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility. Endocrinology (1999) 1.64

Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin. Eur J Biochem (1988) 1.62

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int Immunol (1993) 1.60

Cloning and DNA sequencing of the genes encoding Clostridium josui scaffolding protein CipA and cellulase CelD and identification of their gene products as major components of the cellulosome. J Bacteriol (1998) 1.60

Expression of toll-like receptor 2 on gamma delta T cells bearing invariant V gamma 6/V delta 1 induced by Escherichia coli infection in mice. J Immunol (2000) 1.59

A novel quantitative EEG injury measure of global cerebral ischemia. Clin Neurophysiol (2000) 1.59

High incidence of several malformations in the early human embryos as compared with infants. Biol Neonat (1966) 1.58

Increased expression of multidrug resistance of P-glycoprotein on Th1 cells correlates with drug resistance in rheumatoid arthritis. Arthritis Rheum (1999) 1.57

A procedure to remove protease activities from Bacillus subtilis sporulating cells and their crude extracts. Anal Biochem (1977) 1.57

Prism adaptation of reaching movements: specificity for the velocity of reaching. J Neurosci (1997) 1.56

Cerebellar complex spikes encode both destinations and errors in arm movements. Nature (1998) 1.56

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin. Diabetes (1999) 1.55

The invasion routes of neurovirulent A/Hong Kong/483/97 (H5N1) influenza virus into the central nervous system after respiratory infection in mice. Arch Virol (2002) 1.55

Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells. Cancer Res (1999) 1.55

Cross-antigenicity among EV71 strains from different genogroups isolated in Yamagata, Japan, between 1990 and 2007. Vaccine (2009) 1.55

Restenosis after successful percutaneous transluminal coronary angioplasty: serial angiographic follow-up of 229 patients. J Am Coll Cardiol (1988) 1.55

The coagulation system is activated in idiopathic cardiomyopathy. J Am Coll Cardiol (1995) 1.53

Health-related quality of life in patients with idiopathic pulmonary fibrosis. What is the main contributing factor? Respir Med (2005) 1.51