Published in Genetics on April 01, 1982
Multiple functions of Drosophila heat shock transcription factor in vivo. EMBO J (1997) 2.43
100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. Nat Rev Neurosci (2010) 1.76
Increased persistent Na+ current contributes to seizure in the slamdance bang-sensitive Drosophila mutant. J Neurophysiol (2011) 1.68
Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet (2011) 1.60
Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster. EMBO J (1989) 1.54
stress sensitive B encodes an adenine nucleotide translocase in Drosophila melanogaster. Genetics (1999) 1.51
Towards a molecular understanding of Drosophila hearing. J Neurobiol (2002) 1.48
Inappropriate Neural Activity during a Sensitive Period in Embryogenesis Results in Persistent Seizure-like Behavior. Curr Biol (2015) 1.46
Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila. PLoS Genet (2016) 1.41
Mutations in the Drosophila pushover gene confer increased neuronal excitability and spontaneous synaptic vesicle fusion. Genetics (1996) 1.38
Metabolic disruption in Drosophila bang-sensitive seizure mutants. Genetics (2006) 1.38
The dissonance mutant of courtship song in Drosophila melanogaster: isolation, behavior and cytogenetics. Genetics (1988) 1.38
Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc Natl Acad Sci U S A (2000) 1.35
Cloning of the Drosophila melanogaster meiotic recombination gene mei-218: a genetic and molecular analysis of interval 15E. Genetics (1996) 1.25
From bench to drug: human seizure modeling using Drosophila. Prog Neurobiol (2007) 1.24
Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. Genetics (2010) 1.23
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila. Annu Rev Genet (2012) 1.21
Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila. Genetics (1996) 1.09
Neuropathology in Drosophila mutants with increased seizure susceptibility. Genetics (2008) 1.03
Drosophila couch potato mutants exhibit complex neurological abnormalities including epilepsy phenotypes. Genetics (2005) 1.01
A knock-in model of human epilepsy in Drosophila reveals a novel cellular mechanism associated with heat-induced seizure. J Neurosci (2012) 1.01
Seizure and epilepsy: studies of seizure disorders in Drosophila. Int Rev Neurobiol (2011) 0.99
Calmodulin point mutations affect Drosophila development and behavior. Genetics (1997) 0.99
The Passover locus in Drosophila melanogaster: complex complementation and different effects on the giant fiber neural pathway. Genetics (1990) 0.99
Implication of frequenin in the facilitation of transmitter release in Drosophila. J Physiol (1994) 0.96
Seizure suppression by gain-of-function escargot mutations. Genetics (2005) 0.96
DNA topoisomerase I inhibitors ameliorate seizure-like behaviors and paralysis in a Drosophila model of epilepsy. Neuroscience (2008) 0.95
Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction. PLoS One (2011) 0.94
Mutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in Drosophila. Genetics (2007) 0.92
Neuropathology in Drosophila membrane excitability mutants. Genetics (2005) 0.92
Metabotropic glutamate receptor-mediated use-dependent down-regulation of synaptic excitability involves the fragile X mental retardation protein. J Neurophysiol (2008) 0.90
Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain. Genetics (2009) 0.88
A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease. Brain Behav (2012) 0.88
Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila. Neurobiol Dis (2010) 0.87
Mediators of a long-term movement abnormality in a Drosophila melanogaster model of classic galactosemia. Dis Model Mech (2012) 0.86
A Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome. Hum Mol Genet (2010) 0.86
The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One (2013) 0.85
Drosophila as a model for intractable epilepsy: gilgamesh suppresses seizures in para(bss1) heterozygote flies. G3 (Bethesda) (2013) 0.85
Structural mass spectrometry analysis of lipid changes in a Drosophila epilepsy model brain. Mol Biosyst (2010) 0.85
Mutation of Drosophila focal adhesion kinase induces bang-sensitive behavior and disrupts glial function, axonal conduction and synaptic transmission. Eur J Neurosci (2008) 0.83
Courtship and other behaviors affected by a heat-sensitive, molecularly novel mutation in the cacophony calcium-channel gene of Drosophila. Genetics (2002) 0.83
SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration. Cell Metab (2014) 0.82
Replacement of the glycoinositol phospholipid anchor of Drosophila acetylcholinesterase with a transmembrane domain does not alter sorting in neurons and epithelia but results in behavioral defects. Mol Biol Cell (1996) 0.82
Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochim Biophys Acta (2014) 0.80
A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer. Dis Model Mech (2014) 0.80
Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity. J Cell Sci (2013) 0.80
A new model to study sleep deprivation-induced seizure. Sleep (2015) 0.80
Model systems for studying cellular mechanisms of SCN1A-related epilepsy. J Neurophysiol (2016) 0.79
Cyclic adenosine monophosphate metabolism in synaptic growth, strength, and precision: neural and behavioral phenotype-specific counterbalancing effects between dnc phosphodiesterase and rut adenylyl cyclase mutations. J Neurogenet (2012) 0.78
Mechanical and temperature stressor-induced seizure-and-paralysis behaviors in Drosophila bang-sensitive mutants. J Neurogenet (2012) 0.78
Accelerated bang recovery in Drosophila genderblind mutants. Commun Integr Biol (2008) 0.78
Rapamycin enhances survival in a Drosophila model of mitochondrial disease. Oncotarget (2016) 0.77
Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration. PLoS Genet (2016) 0.77
Intracellular linkers are involved in Mg2+-dependent modulation of the Eag potassium channel. Channels (Austin) (2010) 0.77
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds. PLoS One (2016) 0.76
Nitric oxide mediates glial-induced neurodegeneration in Alexander disease. Nat Commun (2015) 0.76
Drosophila sodium channel mutations: Contributions to seizure-susceptibility. Exp Neurol (2015) 0.76
Mutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans. Ann Clin Transl Neurol (2016) 0.75
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics. PLoS Genet (2016) 0.75
Circadian Clock Dysfunction and Psychiatric Disease: Could Fruit Flies have a Say? Front Neurol (2015) 0.75
Screen for dominant behavioral mutations caused by genomic insertion of P-element transposons in Drosophila: an examination of the integration of viral vector sequences. J Neurogenet (2007) 0.75
Seizure Suppression by High Temperature via cAMP Modulation in Drosophila. G3 (Bethesda) (2016) 0.75
Seizure control through genetic and pharmacological manipulation of Pumilio: a key component of neuronal homeostasis. Dis Model Mech (2016) 0.75
The anatomy and function of a segment of the X chromosome of Drosophila melanogaster. Genetics (1972) 10.56
Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins. Proc Natl Acad Sci U S A (1975) 4.52
Mechanisms of suppression. Adv Genet (1973) 3.32
The behavior of four neurological mutants of Drosophila. Genetics (1969) 2.63
Two mutations of synaptic transmission in Drosophila. Proc R Soc Lond B Biol Sci (1977) 2.60
Purification of the saxitoxin receptor of the sodium channel from rat brain. Proc Natl Acad Sci U S A (1981) 2.44
Genetic dissection of behavior in paramecium. Science (1975) 2.12
Indirect suppression in Caenorhabditis elegans. Genetics (1978) 1.74
Abnormal action potentials associated with the Shaker complex locus of Drosophila. Proc Natl Acad Sci U S A (1981) 1.60
Behavioral mutants of Drosophila melanogaster. III. Isolation and mapping of mutations by direct visual observations of behavioral phenotypes. Mol Gen Genet (1980) 1.47
Behavioral Mutants of DROSOPHILA MELANOGASTER. I. Isolation and Mapping of Mutations Which Decrease Flight Ability. Genetics (1977) 1.33
Genetic analysis of Drosophila neurobiology. Annu Rev Genet (1979) 1.29
Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol A (1994) 4.24
Morphological plasticity of motor axons in Drosophila mutants with altered excitability. J Neurosci (1990) 2.48
DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. J Bacteriol (2001) 2.40
Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvae. J Neurobiol (1993) 2.23
Arrhythmias and the "Holiday Heart": alcohol-associated cardiac rhythm disorders. Am Heart J (1978) 2.06
Neurogenetic analysis of potassium currents in Drosophila: synergistic effects on neuromuscular transmission in double mutants. J Neurogenet (1983) 1.91
Potassium currents in Drosophila: different components affected by mutations of two genes. Science (1983) 1.76
A Drosophila mutation that eliminates a calcium-dependent potassium current. Proc Natl Acad Sci U S A (1986) 1.66
Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade. Science (1991) 1.62
Voltage clamp analysis of membrane currents in larval muscle fibers of Drosophila: alteration of potassium currents in Shaker mutants. J Neurosci (1985) 1.60
Alteration of four identified K+ currents in Drosophila muscle by mutations in eag. Science (1991) 1.59
Drosophila mutants with opposing effects on nerve excitability: genetic and spatial interactions in repetitive firing. J Neurophysiol (1982) 1.58
A Drosophila mutant with a temperature-sensitive block in nerve conduction. Proc Natl Acad Sci U S A (1978) 1.57
Altered habituation of an identified escape circuit in Drosophila memory mutants. J Neurosci (1996) 1.47
Genetic alteration of nerve membrane excitability in temperature-sensitive paralytic mutants of Drosophila melanogaster. Nature (1980) 1.42
Synaptic plasticity in Drosophila memory and hyperexcitable mutants: role of cAMP cascade. J Neurosci (1992) 1.41
Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: histochemical, autoradiographic, in vivo, and in vitro studies. Proc Natl Acad Sci U S A (1987) 1.37
Calcium/calmodulin-dependent protein kinase II and potassium channel subunit eag similarly affect plasticity in Drosophila. Proc Natl Acad Sci U S A (1994) 1.36
Neurogenetics of membrane excitability in Drosophila. Annu Rev Genet (1986) 1.33
Modulation of different K+ currents in Drosophila: a hypothetical role for the Eag subunit in multimeric K+ channels. J Neurosci (1993) 1.32
Dissociated neurons from normal and mutant Drosophila larval central nervous system in cell culture. J Neurosci (1983) 1.30
Reversible inhibition of endocytosis in cultured neurons from the Drosophila temperature-sensitive mutant shibirets1. J Neurogenet (1990) 1.25
Morphometric description of the wandering behavior in Drosophila larvae: aberrant locomotion in Na+ and K+ channel mutants revealed by computer-assisted motion analysis. J Neurogenet (1997) 1.24
Allelic interactions at the shibire locus of Drosophila: effects on behavior. J Neurogenet (1990) 1.23
Differential physiology and morphology of motor axons to ventral longitudinal muscles in larval Drosophila. J Comp Neurol (1994) 1.23
Reversible blockage of neurite development and growth cone formation in neuronal cultures of a temperature-sensitive mutant of Drosophila. J Neurosci (1987) 1.23
Frequency characteristics in the visual system of Drosophila: genetic dissection of electroretinogram components. J Gen Physiol (1977) 1.21
Expression of ion channels and mutational effects in giant Drosophila neurons differentiated from cell division-arrested embryonic neuroblasts. J Neurosci (1991) 1.17
Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction? Science (1976) 1.16
Two-stage design of quantal response studies. Biometrics (1999) 1.15
A novel leg-shaking Drosophila mutant defective in a voltage-gated K(+)current and hypersensitive to reactive oxygen species. J Neurosci (2000) 1.10
Altered branching of serotonin-containing neurons in Drosophila mutants unable to synthesize serotonin and dopamine. J Neurosci (1989) 1.09
Concomitant alterations of physiological and developmental plasticity in Drosophila CaM kinase II-inhibited synapses. Neuron (1994) 1.07
Role of cAMP cascade in synaptic stability and plasticity: ultrastructural and physiological analyses of individual synaptic boutons in Drosophila memory mutants. J Neurosci (2000) 1.07
Quantal basis of photoreceptor spectral sensitivity of Drosophila melanogaster. J Gen Physiol (1975) 1.06
Light-induced voltage noise in the photoreceptor of Drosophila melanogaster. J Gen Physiol (1978) 1.06
Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila. J Neurosci (1998) 1.06
A voltage-clamp analysis of gene-dosage effects of the Shaker locus on larval muscle potassium currents in Drosophila. J Neurosci (1990) 1.04
Interactions of membrane excitability mutations affecting potassium and sodium currents in the flight and giant fiber escape systems of Drosophila. J Comp Physiol A (1992) 1.04
Heteromultimeric interactions among K+ channel subunits from Shaker and eag families in Xenopus oocytes. Neuron (1996) 1.03
Neuronal polymorphism among natural alleles of a cGMP-dependent kinase gene, foraging, in Drosophila. J Neurosci (1999) 1.03
Observations of green fluorescent protein as a fusion partner in genetically engineered Escherichia coli: monitoring protein expression and solubility. Biotechnol Bioeng (2000) 0.97
Small angle neutron and x-ray scattering studies of concentrated protein solutions. II. Cytochrome C. Biopolymers (1988) 0.97
A cGMP-dependent protein kinase gene, foraging, modifies habituation-like response decrement of the giant fiber escape circuit in Drosophila. Learn Mem (2000) 0.96
Persistence of prolonged light-induced conductance change in arthropod photoreceptors on recovery from anoxia. Nature (1976) 0.96
Complete separation of four potassium currents in Drosophila. Neuron (1989) 0.96
Clinical significance of bifid T waves. Jpn Circ J (1986) 0.95
Myocardial composition and function in diabetes. The effects of chronic insulin use. Circ Res (1981) 0.94
Mechanisms of natriuretic-peptide-induced growth inhibition of vascular smooth muscle cells. Cardiovasc Res (1997) 0.93
Auxiliary Hyperkinetic beta subunit of K+ channels: regulation of firing properties and K+ currents in Drosophila neurons. J Neurophysiol (1999) 0.93
Sh and eag K(+) channel subunit interaction in frog oocytes depends on level and time of expression. Biophys J (2000) 0.93
Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade. J Neurosci (1996) 0.93
Acute myocardial infarction in toxic cardiomyopathy without coronary obstruction. Circulation (1975) 0.92
Hermes is a localized factor regulating cleavage of vegetal blastomeres in Xenopus laevis. Dev Biol (2004) 0.92
Alterations in frequency coding and activity dependence of excitability in cultured neurons of Drosophila memory mutants. J Neurosci (1997) 0.91
Properties of potassium currents and their role in membrane excitability in Drosophila larval muscle fibers. J Exp Biol (1990) 0.91
Spontaneous acetylcholine secretion from developing growth cones of Drosophila central neurons in culture: effects of cAMP-pathway mutations. J Neurosci (2000) 0.91
Altered mechanoreceptor response in Drosophila bang-sensitive mutants. J Comp Physiol A (1994) 0.90
Isolation and characterization of mutants for the vesicular acetylcholine transporter gene in Drosophila melanogaster. J Neurobiol (2000) 0.90
Identification and cloning of xp95, a putative signal transduction protein in Xenopus oocytes. J Biol Chem (1999) 0.89
In vivo functional role of the Drosophila hyperkinetic beta subunit in gating and inactivation of Shaker K+ channels. Biophys J (1996) 0.88
Reversal of morphine-induced memory impairment in mice by withdrawal in Morris water maze: possible involvement of cholinergic system. Pharmacol Biochem Behav (2001) 0.87
Differential modulation of potassium currents by cAMP and its long-term and short-term effects: dunce and rutabaga mutants of Drosophila. J Neurogenet (1993) 0.87
A Ca2+/calmodulin-dependent protein kinase modulates Drosophila photoreceptor K+ currents: a role in shaping the photoreceptor potential. J Neurosci (1998) 0.86
Distinct roles of CaMKII and PKA in regulation of firing patterns and K(+) currents in Drosophila neurons. J Neurophysiol (2001) 0.86
Mutational and gene dosage analysis of calcium-activated potassium channels in Drosophila: correlation of micro- and macroscopic currents. Neuron (1990) 0.85
Preclinical cardiomyopathy in chronic alcoholics: a sex difference. Am Heart J (1976) 0.85
Dual muscarinic and nicotinic action on a motor program in Drosophila. J Neurobiol (1991) 0.85
Functional expression of Shaker K+ channels in cultured Drosophila "giant" neurons derived from Sh cDNA transformants: distinct properties, distribution, and turnover. J Neurosci (1995) 0.83
Protective effects of pseudoginsenoside-F11 on scopolamine-induced memory impairment in mice and rats. J Pharm Pharmacol (1999) 0.83
Determination of endogenous acetylcholine release in freely moving rats by transstriatal dialysis coupled to a radioenzymatic assay: effect of drugs. J Neurochem (1987) 0.83
Distinctions in growth cone morphology and motility between monopolar and multipolar neurons in Drosophila CNS cultures. J Neurobiol (1991) 0.83
Development and maintenance of a simple reflex circuit in small-patch mosaics of Drosophila: effects of altered neuronal function and developmental arrest. J Neurobiol (1993) 0.82
Antagonistic effect of pseudoginsenoside-F11 on the behavioral actions of morphine in mice. Pharmacol Biochem Behav (2000) 0.82
Ionic channels in cultured Drosophila neurons. EXS (1993) 0.81
Gender differences in the impact of poverty on health: disparities in risk of diabetes-related amputation. Diabet Med (2014) 0.81
Altered sensitivity to sodium channel-specific neurotoxins in cultured neurons from temperature-sensitive paralytic mutants of Drosophila. J Neurogenet (1984) 0.81
Ionic currents in larval muscles of Drosophila. Int Rev Neurobiol (1999) 0.81
Central projections of peripheral mechanosensory cells with increased excitability in Drosophila mosaics. Dev Biol (1989) 0.80
Control of cyclic AMP levels in isolated fat cells from hamsters. Biochim Biophys Acta (1973) 0.80
Strongly interacting photons in asymmetric quantum well via resonant tunneling. Opt Express (2012) 0.80
Procedures for detection and discrimination of hemophilia A carriers. Chin Med J (Engl) (1982) 0.79
Sacral parasite conjoined twin. Obstet Gynecol (2001) 0.79
DOUBLE-STAINING IN TOTO WITH HEMATOXYLIN AND EOSIN. Science (1940) 0.79
A huge verrucous carcinoma of the lower lip treated with intra-arterial infusion of methotrexate. Br J Dermatol (2004) 0.79
Study on hemophilia A carriers. Procedures for genetic counselling. Chin Med J (Engl) (1983) 0.78
Analysis of mutations affecting sodium channels in Drosophila. Ann N Y Acad Sci (1986) 0.78
Characterization and function of Xnf7 during early development of Xenopus. J Cell Physiol (1997) 0.78
D-1 receptor-linked mechanism modulates cholinergic neurotransmission in rat striatum. J Pharmacol Exp Ther (1987) 0.78
Pseudoginsenoside-F11 attenuates morphine-induced signalling in Chinese hamster ovary-mu cells. Neuroreport (2001) 0.78
Single-channel K+ currents in Drosophila muscle and their pharmacological block. J Membr Biol (1991) 0.78
Involvement of the corticostriatal glutamatergic pathway in ethanol-induced ascorbic acid release in rat striatum. Addict Biol (1999) 0.78
Differentiation and central projections of peripheral sensory cells with action-potential block in Drosophila mosaics. J Neurosci (1986) 0.78
Thyroid status influences rat serum but not brain TRH pyroglutamyl aminopeptidase activities. Endocrinology (1987) 0.78
Identification of novel kinase inhibitors by targeting a kinase-related apoptotic protein-protein interaction network in HeLa cells. Cell Prolif (2014) 0.78
Combinatorial screening for enzyme-mediated coupling. Tyrosinase-catalyzed coupling to create protein--chitosan conjugates. Biomacromolecules (2001) 0.77
Studies on the sedative and hypnotic effects of oleamide in mice. Arzneimittelforschung (1999) 0.77
Opposite effects of sulpiride and SCH 23390 on ethanol-induced striatal ascorbic acid release in intact and 6-hydroxydopamine lesioned rats. Brain Res (2000) 0.76
Inner-ring deiodination of 3,5,3'-triiodothyronine in the in situ perfused guinea pig placenta. J Clin Invest (1985) 0.76
Regulation of firing pattern through modulation of non-Sh K+ currents by calcium/calmodulin-dependent protein kinase II in Drosophila embryonic neurons. Ann N Y Acad Sci (1999) 0.76