Published in Curr Opin Struct Biol on January 23, 2007
Protein folding studied by single-molecule FRET. Curr Opin Struct Biol (2008) 4.33
Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations. Proc Natl Acad Sci U S A (2007) 1.74
Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes. J Biol Chem (2009) 1.45
Isopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenes. J Biol Chem (2010) 1.38
Conformational equilibria in monomeric alpha-synuclein at the single-molecule level. PLoS Biol (2008) 1.37
Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers. Eur Biophys J (2008) 1.29
On the remarkable mechanostability of scaffoldins and the mechanical clamp motif. Proc Natl Acad Sci U S A (2009) 1.21
Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of alpha-helical and beta-sheet protein domains. Proc Natl Acad Sci U S A (2007) 1.20
Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor. Proc Natl Acad Sci U S A (2008) 1.14
The effects of macromolecular crowding on the mechanical stability of protein molecules. Protein Sci (2008) 1.12
Tightening the knot in phytochrome by single-molecule atomic force microscopy. Biophys J (2009) 1.06
Mechanical unfolding of an ankyrin repeat protein. Biophys J (2010) 0.99
An effective strategy for the design of proteins with enhanced mechanical stability. Angew Chem Int Ed Engl (2008) 0.96
Understanding biology by stretching proteins: recent progress. Curr Opin Struct Biol (2010) 0.96
Non-native interactions are critical for mechanical strength in PKD domains. Structure (2009) 0.87
Mechanical unfolding of acylphosphatase studied by single-molecule force spectroscopy and MD simulations. Biophys J (2010) 0.87
Fibers with integrated mechanochemical switches: minimalistic design principles derived from fibronectin. Biophys J (2012) 0.87
The effect of temperature on mechanical resistance of the native and intermediate states of I27. Biophys J (2008) 0.86
Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. Proteins (2009) 0.86
The molecular mechanism underlying mechanical anisotropy of the protein GB1. Biophys J (2012) 0.84
Structural basis for unfolding pathway-dependent stability of proteins: vectorial unfolding versus global unfolding. Protein Sci (2010) 0.82
Molecular basis for the structural stability of an enclosed β-barrel loop. J Mol Biol (2010) 0.81
Tracking unfolding and refolding reactions of single proteins using atomic force microscopy methods. Methods (2013) 0.80
Ultrafast hydrogen exchange reveals specific structural events during the initial stages of folding of cytochrome c. J Am Chem Soc (2013) 0.79
Computational investigation of the effect of thermal perturbation on the mechanical unfolding of titin I27. J Mol Model (2011) 0.78
Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. Nano Lett (2016) 0.78
Single molecule force spectroscopy reveals that electrostatic interactions affect the mechanical stability of proteins. Biophys J (2011) 0.78
Mechanical unfolding of covalently linked GroES: evidence of structural subunit intermediates. Protein Sci (2009) 0.77
Protein unfolding under force: crack propagation in a network. Biophys J (2011) 0.77
Engineering proteins with enhanced mechanical stability by force-specific sequence motifs. Proteins (2012) 0.75
Protein high-force pulling simulations yield low-force results. PLoS One (2012) 0.75
Effects of ligand binding on the mechanical stability of protein GB1 studied by steered molecular dynamics simulation. J Mol Model (2016) 0.75
Methods of probing the interactions between small molecules and disordered proteins. Cell Mol Life Sci (2017) 0.75
The importance of sequence diversity in the aggregation and evolution of proteins. Nature (2005) 2.70
Hidden complexity in the mechanical properties of titin. Nature (2003) 2.51
Single-molecule studies of protein folding. Annu Rev Biochem (2008) 2.22
The folding and evolution of multidomain proteins. Nat Rev Mol Cell Biol (2007) 2.16
Mechanical unfolding of a titin Ig domain: structure of unfolding intermediate revealed by combining AFM, molecular dynamics simulations, NMR and protein engineering. J Mol Biol (2002) 2.00
Parallel protein-unfolding pathways revealed and mapped. Nat Struct Biol (2003) 1.67
Versatile cloning system for construction of multimeric proteins for use in atomic force microscopy. Protein Sci (2002) 1.67
Experimental evidence for a frustrated energy landscape in a three-helix-bundle protein family. Nature (2010) 1.61
Mechanical unfolding of a titin Ig domain: structure of transition state revealed by combining atomic force microscopy, protein engineering and molecular dynamics simulations. J Mol Biol (2003) 1.53
The folding of spectrin domains I: wild-type domains have the same stability but very different kinetic properties. J Mol Biol (2004) 1.40
What contributions to protein side-chain dynamics are probed by NMR experiments? A molecular dynamics simulation analysis. J Mol Biol (2005) 1.40
A simple method for probing the mechanical unfolding pathway of proteins in detail. Proc Natl Acad Sci U S A (2002) 1.39
Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation. J Mol Biol (2005) 1.37
Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins. Nature (2011) 1.37
The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction. J Mol Biol (2005) 1.34
Titin; a multidomain protein that behaves as the sum of its parts. J Mol Biol (2002) 1.30
The folding of spectrin domains II: phi-value analysis of R16. J Mol Biol (2004) 1.29
Surgery or embolisation for varicoceles in subfertile men. Cochrane Database Syst Rev (2009) 1.28
The origin of protein sidechain order parameter distributions. J Am Chem Soc (2004) 1.25
The folding pathway of spectrin R17 from experiment and simulation: using experimentally validated MD simulations to characterize States hinted at by experiment. J Mol Biol (2006) 1.21
Robotic surgery for benign gynaecological disease. Cochrane Database Syst Rev (2012) 1.21
Atomic force microscopy: mechanical unfolding of proteins. Methods (2004) 1.21
Cooperative folding in a multi-domain protein. J Mol Biol (2005) 1.20
Designing an extracellular matrix protein with enhanced mechanical stability. Proc Natl Acad Sci U S A (2007) 1.19
Spectrin R16: broad energy barrier or sequential transition states? Protein Sci (2005) 1.16
BPPred: a Web-based computational tool for predicting biophysical parameters of proteins. Protein Sci (2006) 1.14
Sequence conservation in Ig-like domains: the role of highly conserved proline residues in the fibronectin type III superfamily. J Mol Biol (2002) 1.13
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nat Commun (2012) 1.13
Folding and binding of an intrinsically disordered protein: fast, but not 'diffusion-limited'. J Am Chem Soc (2013) 1.11
Hydrophobic core fluidity of homologous protein domains: relation of side-chain dynamics to core composition and packing. Biochemistry (2004) 1.08
Spectrin domains lose cooperativity in forced unfolding. Biophys J (2006) 1.08
Comparison of the transition states for folding of two Ig-like proteins from different superfamilies. J Mol Biol (2004) 1.05
Biophysical investigations of engineered polyproteins: implications for force data. Biophys J (2004) 1.04
Staphylococcal biofilm-forming protein has a contiguous rod-like structure. Proc Natl Acad Sci U S A (2012) 1.04
Fusion of contrast-enhanced breast MR and mammographic imaging data. Med Image Anal (2003) 1.03
Complex folding kinetics of a multidomain protein. Biophys J (2005) 1.02
Different members of a simple three-helix bundle protein family have very different folding rate constants and fold by different mechanisms. J Mol Biol (2009) 1.00
What can atomic force microscopy tell us about protein folding? Chem Commun (Camb) (2002) 1.00
Folding of a LysM domain: entropy-enthalpy compensation in the transition state of an ideal two-state folder. J Mol Biol (2008) 1.00
Coupled folding and binding of the disordered protein PUMA does not require particular residual structure. J Am Chem Soc (2014) 1.00
Thermodynamic characterisation of two transition states along parallel protein folding pathways. J Mol Biol (2004) 0.99
Plasticity within the obligatory folding nucleus of an immunoglobulin-like domain. J Mol Biol (2007) 0.99
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP). Phys Chem Chem Phys (2011) 0.98
What lessons can be learned from studying the folding of homologous proteins? Methods (2010) 0.97
Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains. Proc Natl Acad Sci U S A (2006) 0.97
Acupuncture for uterine fibroids. Cochrane Database Syst Rev (2010) 0.97
Remarkably fast coupled folding and binding of the intrinsically disordered transactivation domain of cMyb to CBP KIX. J Phys Chem B (2013) 0.97
Studying the folding of multidomain proteins. HFSP J (2008) 0.96
An effective strategy for the design of proteins with enhanced mechanical stability. Angew Chem Int Ed Engl (2008) 0.96
Self-consistent determination of the transition state for protein folding: application to a fibronectin type III domain. Proc Natl Acad Sci U S A (2003) 0.95
Cost-effectiveness analysis of screening for risk of in-hospital falls using physiotherapist clinical judgement. Med Care (2009) 0.94
Multicentre study of delirium in ICU patients using a simple screening tool. Aust Crit Care (2005) 0.93
Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains. J Biol Chem (2009) 0.93
Using model proteins to quantify the effects of pathogenic mutations in Ig-like proteins. J Biol Chem (2006) 0.93
Structural comparison of the two alternative transition states for folding of TI I27. Biophys J (2006) 0.92
Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains. Proc Natl Acad Sci U S A (2012) 0.92
Antioxidants for female subfertility. Cochrane Database Syst Rev (2013) 0.91
Dose-response relationship between physiotherapy resource provision with function and balance improvements in patients following stroke: a multi-centre observational study. J Eval Clin Pract (2010) 0.88
Take home lessons from studies of related proteins. Curr Opin Struct Biol (2012) 0.87
Development and validation of the balance outcome measure for elder rehabilitation. Arch Phys Med Rehabil (2007) 0.87
Characterisation of transition state structures for protein folding using 'high', 'medium' and 'low' {Phi}-values. Protein Eng Des Sel (2008) 0.86
Mouse lymphoma thymidine kinase gene mutation assay: follow-up meeting of the International Workshop on Genotoxicity Testing--Aberdeen, Scotland, 2003--Assay acceptance criteria, positive controls, and data evaluation. Environ Mol Mutagen (2006) 0.86
Topology is the principal determinant in the folding of a complex all-alpha Greek key death domain from human FADD. J Mol Biol (2009) 0.86
Single molecule studies of protein folding using atomic force microscopy. Methods Mol Biol (2007) 0.86
Distinguishing specific and nonspecific interdomain interactions in multidomain proteins. Biophys J (2007) 0.86
Changes in falls risk factors for geriatric diagnostic groups across inpatient, outpatient and domiciliary rehabilitation settings. Disabil Rehabil (2011) 0.85
Crosstalk between the protein surface and hydrophobic core in a core-swapped fibronectin type III domain. J Mol Biol (2007) 0.84
Experiments suggest that simulations may overestimate electrostatic contributions to the mechanical stability of a fibronectin type III domain. J Mol Biol (2007) 0.84
Membrane protein folding makes the transition. Proc Natl Acad Sci U S A (2010) 0.83
The importance of loop length in the folding of an immunoglobulin domain. Protein Eng Des Sel (2004) 0.82
Balance impairment not predictive of falls in geriatric rehabilitation wards. J Gerontol A Biol Sci Med Sci (2008) 0.82
Treatment of heavy menstrual bleeding. BMJ (2010) 0.81
A mechanistic model for amorphous protein aggregation of immunoglobulin-like domains. J Am Chem Soc (2013) 0.81
Biophysics: Rough passage across a barrier. Nature (2013) 0.81
Protein folding: adding a nucleus to guide helix docking reduces landscape roughness. J Mol Biol (2012) 0.81
The folding pathway of a single domain in a multidomain protein is not affected by its neighbouring domain. J Mol Biol (2008) 0.81
Surgery or embolisation for varicoceles in subfertile men. Cochrane Database Syst Rev (2008) 0.80
Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions. J Cell Physiol (2005) 0.80
Pentoxifylline for endometriosis. Cochrane Database Syst Rev (2012) 0.80
Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women. Cochrane Database Syst Rev (2008) 0.79
Further validation of the Balance Outcome Measure for Elder Rehabilitation. Arch Phys Med Rehabil (2011) 0.78
FnIII domains: predicting mechanical stability. Structure (2004) 0.77
Manipulating the stability of fibronectin type III domains by protein engineering. Nanotechnology (2008) 0.77
Mouse lymphoma thymidine kinase gene mutation assay: meeting of the International Workshop on Genotoxicity Testing, San Francisco, 2005, recommendations for 24-h treatment. Mutat Res (2006) 0.77
Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins--studies of isolated domains are not enough. FEBS J (2013) 0.76
Two immunoglobulin tandem proteins with a linking β-strand reveal unexpected differences in cooperativity and folding pathways. J Mol Biol (2011) 0.76
Paediatric thoracic tumours presenting as empyema. Pediatr Surg Int (2006) 0.75
Football for life versus antidoping for the masses: ethical antidoping issues and solutions based on the extenuating experiences of an elite footballer competing while undergoing treatment for metastatic testicular cancer. Br J Sports Med (2014) 0.75
What is a systematic review? Evid Based Nurs (2011) 0.75
Protein engineering and design: from first principles to new technologies. Curr Opin Struct Biol (2010) 0.75
Pentoxifylline versus medical therapies for subfertile women with endometriosis. Cochrane Database Syst Rev (2009) 0.75
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Learning from Nature to design new biomolecules. Curr Opin Struct Biol (2012) 0.75