Published in Invest Ophthalmol Vis Sci on February 01, 2007
Extracellular matrix in the trabecular meshwork. Exp Eye Res (2008) 2.29
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshwork. Invest Ophthalmol Vis Sci (2011) 1.15
Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp Eye Res (2009) 1.14
Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem (2014) 1.12
CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration. Br J Cancer (2011) 1.12
Biological properties of trabecular meshwork cells. Exp Eye Res (2008) 1.06
Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Invest Ophthalmol Vis Sci (2011) 1.05
Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucoma. Exp Eye Res (2015) 1.02
Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.02
Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells. Exp Eye Res (2011) 0.99
PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells. Free Radic Res (2009) 0.98
The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. J Ocul Pharmacol Ther (2014) 0.97
Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression. Exp Eye Res (2008) 0.97
Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2010) 0.96
Intraocular pressure homeostasis: maintaining balance in a high-pressure environment. J Ocul Pharmacol Ther (2014) 0.92
Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis (2011) 0.89
Aqueous humor outflow: dynamics and disease. Invest Ophthalmol Vis Sci (2015) 0.89
BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression. Cell Oncol (Dordr) (2011) 0.89
Aqueous humor TGF-β2 levels in patients with open-angle glaucoma: A meta-analysis. Mol Vis (2015) 0.87
Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice. Exp Eye Res (2013) 0.85
Regulation of SPARC by transforming growth factor β2 in human trabecular meshwork. Invest Ophthalmol Vis Sci (2013) 0.85
Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells. Exp Eye Res (2013) 0.85
Connective tissue growth factor-mediated upregulation of neuromedin U expression in trabecular meshwork cells and its role in homeostasis of aqueous humor outflow. Invest Ophthalmol Vis Sci (2012) 0.84
Preventive effects of omega-3 and omega-6 Fatty acids on peroxide mediated oxidative stress responses in primary human trabecular meshwork cells. PLoS One (2012) 0.82
Matricellular proteins in the trabecular meshwork: review and update. J Ocul Pharmacol Ther (2014) 0.81
The many faces of the trabecular meshwork cell. Exp Eye Res (2016) 0.80
Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury. Histochem Cell Biol (2011) 0.80
Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia. Mol Vis (2014) 0.79
The Trabecular Meshwork: A Basic Review of Form and Function. J Ocul Biol (2014) 0.79
TGF-β2-mediated ocular hypertension is attenuated in SPARC-null mice. Invest Ophthalmol Vis Sci (2014) 0.78
When 1+1>2: Nanostructured composites for hard tissue engineering applications. Mater Sci Eng C Mater Biol Appl (2015) 0.78
Secreted Protein Acidic and Rich in Cysteine in Ocular Tissue. J Ocul Pharmacol Ther (2015) 0.77
Anterior segment alterations and comparative aqueous humor proteomics in the buphthalmic rabbit (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2011) 0.76
Gremlin Induces Ocular Hypertension in Mice Through Smad3-Dependent Signaling. Invest Ophthalmol Vis Sci (2015) 0.76
Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork. Exp Eye Res (2015) 0.76
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2012) 0.76
The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells. J Cell Mol Med (2015) 0.76
Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork. Invest Ophthalmol Vis Sci (2017) 0.75
Functional Anatomy of the Outflow Facilities. Vet Clin North Am Small Anim Pract (2015) 0.75
Crosstalk between TGFβ and Wnt signaling pathways in the human trabecular meshwork. Exp Eye Res (2016) 0.75
Bone Morphogenetic Protein-7 Suppresses TGFβ2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci (2017) 0.75
Recent Developments in Understanding the Role of Aqueous Humor Outflow in Normal and Primary Open Angle Glaucoma. Curr Ophthalmol Rep (2015) 0.75
Rho GTPase signaling promotes constitutive expression and release of TGF-β2 by human trabecular meshwork cells. Exp Eye Res (2015) 0.75
Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells. Invest Ophthalmol Vis Sci (2017) 0.75
Gene transfer to the outflow tract. Exp Eye Res (2016) 0.75
Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol Cell Biol (2004) 2.23
Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. Bioessays (2004) 1.96
Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol (2010) 1.48
The role of TGF-β in the pathogenesis of primary open-angle glaucoma. Cell Tissue Res (2011) 1.47
Posterior vitreous detachment induced by microplasmin. Invest Ophthalmol Vis Sci (2004) 1.41
Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet (2012) 1.33
Modulation of extracellular matrix turnover in the trabecular meshwork. Exp Eye Res (2009) 1.29
Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork. Am J Pathol (2012) 1.22
Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells. Exp Eye Res (2009) 1.22
Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mech Dev (2002) 1.20
Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One (2009) 1.19
Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination. Dev Cell (2012) 1.17
Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp Eye Res (2009) 1.14
Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments. Invest Ophthalmol Vis Sci (2002) 1.14
Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells. J Neurosci (2010) 1.13
Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice. J Neurosci (2005) 1.10
Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics Chromatin (2010) 1.10
Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve. Glia (2011) 1.09
Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-beta1 and dexamethasone in vitro. Exp Eye Res (2004) 1.09
Genetic dissection of Pax6 dosage requirements in the developing mouse eye. Hum Mol Genet (2005) 1.06
The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination. Mol Cell Biol (2005) 1.05
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes. PLoS Genet (2013) 1.05
Effects of oxidative stress in trabecular meshwork cells are reduced by prostaglandin analogues. Invest Ophthalmol Vis Sci (2008) 1.05
Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp Eye Res (2008) 1.05
Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp Eye Res (2003) 1.04
Norrin: molecular and functional properties of an angiogenic and neuroprotective growth factor. Prog Retin Eye Res (2012) 1.02
In vitro safety of intravitreal moxifloxacin for endophthalmitis treatment. J Cataract Refract Surg (2008) 1.01
The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost. Invest Ophthalmol Vis Sci (2009) 1.01
Effect of heparin II domain of fibronectin on aqueous outflow in cultured anterior segments of human eyes. Invest Ophthalmol Vis Sci (2003) 1.01
Overexpression and properties of wild-type and Tyr437His mutated myocilin in the eyes of transgenic mice. Invest Ophthalmol Vis Sci (2005) 1.00
Different collagen types define two types of idiopathic epiretinal membranes. Histopathology (2011) 0.98
Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release. Invest Ophthalmol Vis Sci (2009) 0.97
Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression. Exp Eye Res (2008) 0.97
Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice. Dev Dyn (2002) 0.96
Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet (2010) 0.95
Pax6 dosage requirements in iris and ciliary body differentiation. Dev Biol (2009) 0.93
Role of bestrophin-1 in store-operated calcium entry in retinal pigment epithelium. Pflugers Arch (2012) 0.93
Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells. Histochem Cell Biol (2008) 0.92
Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage. Neurobiol Dis (2012) 0.92
Transgenic studies on the role of optineurin in the mouse eye. Exp Eye Res (2006) 0.92
Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice. J Neurosci (2010) 0.92
Biochemical and morphological analysis of basement membrane component expression in corneoscleral and cribriform human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2006) 0.92
Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism. FASEB J (2005) 0.91
TGF-{beta}2 induces senescence-associated changes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2010) 0.90
Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves. Glia (2003) 0.90
The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillaries. Exp Eye Res (2012) 0.89
Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes. Invest Ophthalmol Vis Sci (2008) 0.88
Perfusion with the olfactomedin domain of myocilin does not affect outflow facility. Invest Ophthalmol Vis Sci (2003) 0.88
Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage. Histochem Cell Biol (2015) 0.88
Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem Cell Biol (2012) 0.87
The different functions of Norrin. Adv Exp Med Biol (2012) 0.86
Progressive retinal degeneration and glial activation in the CLN6 (nclf) mouse model of neuronal ceroid lipofuscinosis: a beneficial effect of DHA and curcumin supplementation. PLoS One (2013) 0.86
The effect of TGF-beta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes. Invest Ophthalmol Vis Sci (2008) 0.85
Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma. Hum Mol Genet (2010) 0.84
Topography of diabetic macular oedema compared with fluorescein angiography. Acta Ophthalmol Scand (2007) 0.84
The role of bestrophin-1 in intracellular Ca(2+) signaling. Adv Exp Med Biol (2014) 0.84
SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina. Histochem Cell Biol (2017) 0.84
TGF-β signaling protects retinal neurons from programmed cell death during the development of the mammalian eye. J Neurosci (2013) 0.84
The role of Müller glia and microglia in glaucoma. Cell Tissue Res (2013) 0.83
Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10. Glia (2012) 0.83
The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment. Eur J Pharm Biopharm (2015) 0.83
Rho GTPase inactivation impairs lens growth and integrity. Lab Invest (2002) 0.82
Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proc Natl Acad Sci U S A (2013) 0.82
On the use of immortalized ocular cell lines in vision research: the unfortunate story of RGC-5. Exp Eye Res (2013) 0.81
The expression of myocilin during murine eye development. Graefes Arch Clin Exp Ophthalmol (2004) 0.81
Focus on molecules: Norrin. Exp Eye Res (2011) 0.81
Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection. Adv Exp Med Biol (2014) 0.81
Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins. Exp Eye Res (2011) 0.81
Identification of adult stem cells in Schwalbe's line region of the primate eye. Invest Ophthalmol Vis Sci (2014) 0.81
Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury. Histochem Cell Biol (2011) 0.80
Osteopontin as a serologic marker for metastatic uveal melanoma: results of a pilot study. Am J Ophthalmol (2006) 0.80
Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis. Kidney Int (2005) 0.80
Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis. Nephrol Dial Transplant (2010) 0.80
SPARC is expressed in scars of the Tenon's capsule and mediates scarring properties of human Tenon's fibroblasts in vitro. Mol Vis (2011) 0.80
Intraocular Pressure and the Mechanisms Involved in Resistance of the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways. Prog Mol Biol Transl Sci (2015) 0.79
Localization of collagen XVIII and endostatin in the human eye. Curr Eye Res (2005) 0.79
Neuroprotection in glaucoma. Cell Tissue Res (2013) 0.79
Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol (2007) 0.79
The origin of extrinsic nitrergic axons supplying the human eye. J Anat (2005) 0.78
Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles. Small (2012) 0.78
Myocilin in the trabecular meshwork of eyes with primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol (2009) 0.77
Optineurin associates with the podocyte Golgi complex to maintain its structure. Cell Tissue Res (2014) 0.77
The effect of temperature on gene silencing by siRNAs: implications for silencing in the anterior chamber of the eye. Exp Eye Res (2006) 0.77
Current aspects of aqueous humor dynamics and glaucoma. Exp Eye Res (2009) 0.77
The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells. J Cell Mol Med (2015) 0.76
Programmed cell death during retinal development of the mouse eye. Adv Exp Med Biol (2014) 0.76
The prostaglandin f2α analog fluprostenol attenuates the fibrotic effects of connective tissue growth factor on human trabecular meshwork cells. J Ocul Pharmacol Ther (2014) 0.75
N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: a mouse model of acute retinal ganglion cell damage. Methods Mol Biol (2013) 0.75
Ex vivo excimer laser ablation of cornea guttata and ROCK inhibitor-aided endothelial recolonization of ablated central cornea. Acta Ophthalmol (2020) 0.75
Focus on Molecules: Myocilin/TIGR. Exp Eye Res (2005) 0.75
Human anterior lens capsule serving as a substrate for human trabecular meshwork cells cultivation. Cell Tissue Bank (2012) 0.75
Ambiguous role of glucocorticoids on survival of retinal neurons. Adv Exp Med Biol (2014) 0.75
Norrin protects optic nerve axons from degeneration in a mouse model of glaucoma. Sci Rep (2017) 0.75
Mapping of the retinal pigment epithelium in exudative age related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2005) 0.75