Published in J Am Coll Cardiol on January 22, 2007
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation (2010) 2.94
Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation (2011) 2.36
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart Rhythm (2009) 1.87
Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation. J Am Coll Cardiol (2008) 1.77
Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation. Heart Rhythm (2010) 1.77
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. J Physiol (2009) 1.74
Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation. J Mol Cell Cardiol (2009) 1.31
Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation. J Am Coll Cardiol (2012) 1.27
Genetics of atrial fibrillation: rare mutations, common polymorphisms, and clinical relevance. Heart Rhythm (2007) 1.23
Genetics of atrial fibrillation. Heart Fail Clin (2010) 1.15
Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol (2013) 1.11
Atrial fibrillation in congestive heart failure. Heart Fail Clin (2010) 1.07
Genetics of atrial fibrillation: implications for future research directions and personalized medicine. Circ Arrhythm Electrophysiol (2010) 1.01
Ion channel mutations in AF: signal or noise? Heart Rhythm (2008) 0.99
Genetics of atrial fibrillation. Cardiol Clin (2009) 0.96
Genetics of atrial fibrillation: from families to genomes. J Hum Genet (2015) 0.96
Monogenic atrial fibrillation as pathophysiological paradigms. Cardiovasc Res (2010) 0.94
Voltage-gated channel mechanosensitivity: fact or friction? Front Physiol (2011) 0.93
Atrial fibrillation: the role of common and rare genetic variants. Eur J Hum Genet (2013) 0.92
Cardiac Arrhythmia: In vivo screening in the zebrafish to overcome complexity in drug discovery. Expert Opin Drug Discov (2010) 0.89
Genetics of atrial fibrillation. Med Clin North Am (2008) 0.88
Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling. J Physiol (2012) 0.86
A contemporary review on the genetic basis of atrial fibrillation. Methodist Debakey Cardiovasc J (2014) 0.84
Interpreting genetic effects through models of cardiac electromechanics. Am J Physiol Heart Circ Physiol (2012) 0.84
Ion Channels in the Heart. Compr Physiol (2015) 0.83
Association of KCNE1 genetic polymorphisms with atrial fibrillation in a Chinese Han population. Genet Test Mol Biomarkers (2012) 0.81
Genomics of Atrial Fibrillation. Curr Cardiol Rep (2016) 0.80
Lone AF - etiologic factors and genetic insights into pathophysiolgy. J Atr Fibrillation (2010) 0.80
Paired-like homeodomain 2: a novel therapeutic target for atrial fibrillation? Front Genet (2014) 0.79
Heuristic methods for finding pathogenic variants in gene coding sequences. J Am Heart Assoc (2012) 0.79
KCNE1 rs1805127 polymorphism increases the risk of atrial fibrillation: a meta-analysis of 10 studies. PLoS One (2013) 0.78
Screening of the ito regulatory subunit klf15 in patients with early-onset lone atrial fibrillation. Front Genet (2013) 0.78
Personalized medicine and atrial fibrillation: will it ever happen? BMC Med (2012) 0.76
Mechanosensitive gating of Kv channels. PLoS One (2015) 0.76
Genetic Discoveries in Atrial Fibrillation and Implications for Clinical Practice. Arrhythm Electrophysiol Rev (2014) 0.76
Angiotensin II type 1 receptor mediates partially hyposmotic-induced increase of I (Ks) current in guinea pig atrium. Pflugers Arch (2009) 0.76
The Role of Pharmacogenetics in Atrial Fibrillation Therapeutics: Is Personalized Therapy in Sight? J Cardiovasc Pharmacol (2016) 0.76
Arrhythmia pharmacogenomics: methodological considerations. Curr Pharm Des (2009) 0.76
Comprehensive mutation scanning of KCNQ1 in 111 Han Chinese patients with lone atrial fibrillation. Heart Asia (2010) 0.75
Genetic Risk Scores for Atrial Fibrillation: Do They Improve Risk Estimation? Can J Cardiol (2016) 0.75
KCNA5 gene polymorphism associate with idiopathic atrial fibrillation. Int J Clin Exp Med (2015) 0.75
Genotype influence in responses to therapy for atrial fibrillation. Expert Rev Cardiovasc Ther (2016) 0.75
The burden of proof: The current state of atrial fibrillation prevention and treatment trials. Heart Rhythm (2017) 0.75
Is endothelin gene polymorphism associated with postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting? Ann Card Anaesth (2017) 0.75
Association between KCNE1 G38S gene polymorphism and risk of atrial fibrillation: A PRISMA-compliant meta-analysis. Medicine (Baltimore) (2017) 0.75
Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet (2012) 10.53
Founder effects in the assessment of HIV polymorphisms and HLA allele associations. Science (2007) 4.60
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A (2002) 4.37
A test of climate, sun, and culture relationships from an 1810-year Chinese cave record. Science (2008) 3.94
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. J Exp Med (2005) 3.68
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A (2002) 3.59
Influence of HLA-C expression level on HIV control. Science (2013) 3.27
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nat Neurosci (2002) 3.09
Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers. Angew Chem Int Ed Engl (2011) 2.79
Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparins. Science (2011) 2.79
Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice. J Clin Invest (2004) 2.67
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels. Cell (2010) 2.50
Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature (2011) 2.36
Analysis of protein sequence and interaction data for candidate disease gene prediction. Nucleic Acids Res (2006) 2.30
Clonal vaccinia virus grown in cell culture as a new smallpox vaccine. Nat Med (2003) 2.27
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2007) 2.25
Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures. Chem Biol (2007) 2.20
Solution structures of chemoenzymatically synthesized heparin and its precursors. J Am Chem Soc (2008) 2.02
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest (2007) 2.00
Approach to low back pain. Chiropractic. Aust Fam Physician (2014) 1.98
Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes. Europace (2013) 1.97
Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Am J Hum Genet (2007) 1.97
Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy. Nat Genet (2011) 1.95
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development (2005) 1.90
Enzymatic redesigning of biologically active heparan sulfate. J Biol Chem (2005) 1.89
NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood (2002) 1.87
Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome. J Am Coll Cardiol (2003) 1.86
Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy. Circ Res (2009) 1.83
Gating currents associated with intramembrane charge displacement in HERG potassium channels. Proc Natl Acad Sci U S A (2003) 1.82
High-throughput microarray detection of olfactory receptor gene expression in the mouse. Proc Natl Acad Sci U S A (2004) 1.82
Limb ischemic preconditioning reduces heart and lung injury after an open heart operation in infants. Pediatr Cardiol (2009) 1.81
Continuous viral escape and selection by autologous neutralizing antibodies in drug-naive human immunodeficiency virus controllers. J Virol (2008) 1.80
The test-retest reliability of centre of pressure measures in bipedal static task conditions--a systematic review of the literature. Gait Posture (2010) 1.78
Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. J Biol Chem (2002) 1.78
Northern Hemisphere summer monsoon intensified by mega-El Nino/southern oscillation and Atlantic multidecadal oscillation. Proc Natl Acad Sci U S A (2013) 1.75
Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1. J Biol Chem (2002) 1.74
Implementation of ion/ion reactions in a quadrupole/time-of-flight tandem mass spectrometer. Anal Chem (2006) 1.72
Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol (2004) 1.72
A live, attenuated recombinant West Nile virus vaccine. Proc Natl Acad Sci U S A (2006) 1.72
ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain)--a second-generation smallpox vaccine for biological defense. Int J Infect Dis (2004) 1.70
'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70
Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection. AIDS (2008) 1.67
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol (2008) 1.64
Chemoenzymatic design of heparan sulfate oligosaccharides. J Biol Chem (2010) 1.64
Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses. J Infect Dis (2005) 1.58
Hand-held dynamometry correlation with the gold standard isokinetic dynamometry: a systematic review. PM R (2011) 1.58
Structural basis of Rab5-Rabaptin5 interaction in endocytosis. Nat Struct Mol Biol (2004) 1.57
Interface engineered BaTiO₃/SrTiO₃ heterostructures with optimized high-frequency dielectric properties. ACS Appl Mater Interfaces (2012) 1.52
A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1. J Gen Virol (2004) 1.51
Calcitriol restores renovascular function in estrogen-deficient rats through downregulation of cyclooxygenase-2 and the thromboxane-prostanoid receptor. Kidney Int (2013) 1.49
Bone morphogenic protein-4 contributes to venous endothelial dysfunction in patients with diabetes undergoing coronary revascularization. Ann Thorac Surg (2013) 1.46
Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol (2007) 1.46
LMP2/LMP7 gene variant: a risk factor for intestinal Mycobacterium tuberculosis infection in the Chinese population. J Gastroenterol Hepatol (2011) 1.45
Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. Anal Chem (2009) 1.45
Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts. J Virol (2006) 1.44
Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates. J Infect Dis (2010) 1.43
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes. Genes Chromosomes Cancer (2002) 1.42
Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1. J Biol Chem (2004) 1.41
Design of biologically active heparan sulfate and heparin using an enzyme-based approach. Nat Prod Rep (2009) 1.39
Differentiating fall-prone and healthy adults using local dynamic stability. Ergonomics (2008) 1.39
Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1. J Biol Chem (2004) 1.38
Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells. Mol Cancer Res (2011) 1.37
The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation. PLoS One (2011) 1.35
Genes and atrial fibrillation: a new look at an old problem. Circulation (2007) 1.33
Optimization of supercritical carbon dioxide extraction of silkworm pupal oil applying the response surface methodology. Bioresour Technol (2009) 1.33
Control of the heparosan N-deacetylation leads to an improved bioengineered heparin. Appl Microbiol Biotechnol (2011) 1.33
Intercalation of few-layer graphite flakes with FeCl3: Raman determination of Fermi level, layer by layer decoupling, and stability. J Am Chem Soc (2011) 1.33
Engineering sulfotransferases to modify heparan sulfate. Nat Chem Biol (2008) 1.32
Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1. Biochem J (2005) 1.31
Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction. Prog Biophys Mol Biol (2008) 1.31
Center of pressure excursion as a measure of balance performance in patients with non-specific low back pain compared to healthy controls: a systematic review of the literature. Eur Spine J (2010) 1.30
Mating behaviour, life history and adaptation to insecticides determine species exclusion between whiteflies. J Anim Ecol (2010) 1.29
Dwarf 88, a novel putative esterase gene affecting architecture of rice plant. Plant Mol Biol (2009) 1.29
Temperature dependence of human ether-a-go-go-related gene K+ currents. Am J Physiol Cell Physiol (2006) 1.29
Enzymatic synthesis of heparin related polysaccharides on sensor chips: rapid screening of heparin-protein interactions. Biochem Biophys Res Commun (2005) 1.29
Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Dev (2007) 1.28
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol (2005) 1.27
Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis. Hum Mol Genet (2008) 1.26
Redox-dependent conformational changes in cytochrome C oxidase suggest a gating mechanism for proton uptake. Biochemistry (2009) 1.26
Statistical resolution of ambiguous HLA typing data. PLoS Comput Biol (2008) 1.25
Chiral sum frequency generation spectroscopy for characterizing protein secondary structures at interfaces. J Am Chem Soc (2011) 1.24
Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations. PLoS One (2011) 1.24
Chromosome 6 abnormalities are recurrent in synovial chondromatosis. Cancer Genet Cytogenet (2003) 1.24
Isocyanate vapor-induced antigenicity of human albumin. J Allergy Clin Immunol (2004) 1.24
Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452). AIDS (2008) 1.23
Classification and potential mechanisms of intravascular ultrasound patterns of stent fracture. Am J Cardiol (2009) 1.23
Molecular cloning and function analysis of the stay green gene in rice. Plant J (2007) 1.22
MicroRNA profiling of sporadic and hereditary medullary thyroid cancer identifies predictors of nodal metastasis, prognosis, and potential therapeutic targets. Clin Cancer Res (2011) 1.22
Alpha-cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects. Hum Mol Genet (2010) 1.22
Cardiac hypertrophy in mice with long-chain acyl-CoA dehydrogenase or very long-chain acyl-CoA dehydrogenase deficiency. Lab Invest (2009) 1.22
Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions. Chemistry (2010) 1.22
Synthetic heparin. Curr Opin Pharmacol (2012) 1.21
Using a 3-O-sulfated heparin octasaccharide to inhibit the entry of herpes simplex virus type 1. Biochemistry (2008) 1.21
Adiponectin and its receptors are expressed in adult ventricular cardiomyocytes and upregulated by activation of peroxisome proliferator-activated receptor gamma. J Mol Cell Cardiol (2007) 1.21
miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2. Cancer Lett (2013) 1.21
Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate. Biochemistry (2005) 1.21