Published in Structure on February 01, 2007
A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol (2010) 3.70
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
Rab GEFs and GAPs. Curr Opin Cell Biol (2010) 2.73
Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell (2008) 2.09
Crystal structure of the Sec4p.Sec2p complex in the nucleotide exchanging intermediate state. Proc Natl Acad Sci U S A (2007) 1.24
Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein. Genes Dev (2013) 0.98
Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. J Mol Biol (2009) 0.94
Structural and functional insights on the Myosin superfamily. Bioinform Biol Insights (2012) 0.83
A guaninine nucleotide exchange factor is a component of the meiotic spindle pole body in Schizosaccharomyces pombe. Mol Biol Cell (2010) 0.82
Miranda cargo-binding domain forms an elongated coiled-coil homodimer in solution: implications for asymmetric cell division in Drosophila. Protein Sci (2008) 0.79
Yarrowia lipolytica vesicle-mediated protein transport pathways. BMC Evol Biol (2007) 0.78
New insights into the molecular mechanism of the Rab GTPase Sec4p activation. BMC Struct Biol (2015) 0.75
Crystallization and crystallographic analysis of yeast Sec2p, a guanine nucleotide-exchange factor for the yeast Rab GTPase Sec4p. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.75
Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron (2004) 6.71
alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol (2002) 6.64
Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell (2006) 5.70
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell (2002) 5.64
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol (2002) 5.52
Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor. Proc Natl Acad Sci U S A (2006) 3.78
Dodeca-CLE peptides as suppressors of plant stem cell differentiation. Science (2006) 3.37
ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding. EMBO J (2003) 3.14
Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains. Nature (2008) 2.94
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion. Nat Struct Biol (2003) 2.71
Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J (2004) 2.60
Conformational transition of Sec machinery inferred from bacterial SecYE structures. Nature (2008) 2.48
Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme. Cell (2003) 2.29
Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80. EMBO J (2009) 2.14
Crystal structure of the MgtE Mg2+ transporter. Nature (2007) 2.00
Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol Cell (2002) 1.98
Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol (2007) 1.90
Structure and function of Zucchini endoribonuclease in piRNA biogenesis. Nature (2012) 1.90
Crystal structure of autotaxin and insight into GPCR activation by lipid mediators. Nat Struct Mol Biol (2011) 1.87
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase. J Biol Chem (2006) 1.66
Unexpectedly High Prevalence of Acquired von Willebrand Syndrome in Patients with Severe Aortic Stenosis as Evaluated with a Novel Large Multimer Index. J Atheroscler Thromb (2015) 1.60
Insulin-like growth factor axis (insulin-like growth factor-I/insulin-like growth factor-binding protein-3) as a prognostic predictor of heart failure: association with adiponectin. Eur J Heart Fail (2010) 1.54
Structural basis of replication origin recognition by the DnaA protein. Nucleic Acids Res (2003) 1.54
Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme. Structure (2004) 1.53
Snapshots of tRNA sulphuration via an adenylated intermediate. Nature (2006) 1.51
Structure and function of a membrane component SecDF that enhances protein export. Nature (2011) 1.51
Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein. J Biol Chem (2003) 1.49
Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3. EMBO J (2009) 1.48
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets. J Biol Chem (2003) 1.45
Structural basis of RNA-dependent recruitment of glutamine to the genetic code. Science (2006) 1.45
Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc Natl Acad Sci U S A (2013) 1.45
Functional convergence of two lysyl-tRNA synthetases with unrelated topologies. Nat Struct Biol (2002) 1.43
Mutational separation of two pathways for editing by a class I tRNA synthetase. Mol Cell (2002) 1.42
Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (2014) 1.42
Characterization of the antiplatelet effect of aspirin at enrollment and after 2-year follow-up in a real clinical setting in Japan. Circ J (2010) 1.41
Structural insight into the membrane insertion of tail-anchored proteins by Get3. Genes Cells (2009) 1.40
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation. EMBO J (2012) 1.39
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res (2012) 1.37
Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions. Blood (2005) 1.37
RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia (2012) 1.36
Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex. Proc Natl Acad Sci U S A (2010) 1.35
Structural basis for template-independent RNA polymerization. Nature (2004) 1.35
Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature (2013) 1.34
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. Mol Cell Biol (2007) 1.34
Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nat Struct Mol Biol (2005) 1.34
A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase. Nat Struct Mol Biol (2004) 1.34
Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I and class II lysyl-tRNA synthetases. Mol Cell (2003) 1.33
Assembly of two distinct dimers and higher-order oligomers from full-length tau. Eur J Neurosci (2007) 1.31
Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. EMBO J (2012) 1.30
Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family. J Biol Chem (2005) 1.30
Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality. Nature (2008) 1.28
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA. J Mol Biol (2007) 1.25
Crystal structure of the Sec4p.Sec2p complex in the nucleotide exchanging intermediate state. Proc Natl Acad Sci U S A (2007) 1.24
Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res (2010) 1.22
The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J Biol Chem (2009) 1.21
Perforin gene mutations in adult-onset hemophagocytic lymphohistiocytosis. Haematologica (2007) 1.21
Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis. EMBO J (2009) 1.20
Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation. Nucleic Acids Res (2007) 1.20
Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1). J Biol Chem (2002) 1.20
Endoplasmic reticulum stress increases myofiber formation in vitro. FASEB J (2007) 1.18
The carboxy-terminal domain of the XPC protein plays a crucial role in nucleotide excision repair through interactions with transcription factor IIH. DNA Repair (Amst) (2002) 1.18
Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex. Proc Natl Acad Sci U S A (2011) 1.18
Complete crystallographic analysis of the dynamics of CCA sequence addition. Nature (2006) 1.17
Selenomethionine incorporation into a protein by cell-free synthesis. J Struct Funct Genomics (2002) 1.17
Structure, dynamics, and function of RNA modification enzymes. Curr Opin Struct Biol (2008) 1.17
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood (2009) 1.16
Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin. FEBS Lett (2009) 1.16
Involvement of nectin in the localization of junctional adhesion molecule at tight junctions. Oncogene (2002) 1.16
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase. Nature (2009) 1.15
Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Genes Cells (2003) 1.15
Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion. J Cell Biol (2012) 1.14
An alpha2-macroglobulin-like protein is the cue to gregarious settlement of the barnacle Balanus amphitrite. Proc Natl Acad Sci U S A (2006) 1.13
Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6). J Biol Chem (2013) 1.12
Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3. Nat Struct Mol Biol (2010) 1.11
Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog. EMBO J (2006) 1.11
Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study. Proc Natl Acad Sci U S A (2008) 1.11