Published in Nature on January 22, 2012
Optogenetic investigation of neural circuits underlying brain disease in animal models. Nat Rev Neurosci (2012) 4.35
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Atomistic design of microbial opsin-based blue-shifted optogenetics tools. Nat Commun (2015) 0.84
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Tuning the primary reaction of channelrhodopsin-2 by imidazole, pH, and site-specific mutations. Biophys J (2012) 0.83
Comparison of the structural changes occurring during the primary phototransition of two different channelrhodopsins from Chlamydomonas algae. Biochemistry (2014) 0.83
Proton transfers in a channelrhodopsin-1 studied by Fourier transform infrared (FTIR) difference spectroscopy and site-directed mutagenesis. J Biol Chem (2015) 0.82
Direct observation of protein microcrystals in crystallization buffer by atmospheric scanning electron microscopy. Int J Mol Sci (2012) 0.82
Role of a helix B lysine residue in the photoactive site in channelrhodopsins. Biophys J (2014) 0.82
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Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1. Mol Ther (2014) 0.82
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The primary photoreaction of channelrhodopsin-1: wavelength dependent photoreactions induced by ground-state heterogeneity. Front Mol Biosci (2015) 0.81
Chimeras of channelrhodopsin-1 and -2 from Chlamydomonas reinhardtii exhibit distinctive light-induced structural changes from channelrhodopsin-2. J Biol Chem (2015) 0.81
The photochemical determinants of color vision: revealing how opsins tune their chromophore's absorption wavelength. Bioessays (2013) 0.81
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Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity. J Biol Chem (2015) 0.79
Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci U S A (2015) 0.79
Re-introduction of transmembrane serine residues reduce the minimum pore diameter of channelrhodopsin-2. PLoS One (2012) 0.79
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Optogenetic stimulation of the auditory nerve. J Vis Exp (2014) 0.78
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Time-resolved infrared spectroscopic techniques as applied to channelrhodopsin. Front Mol Biosci (2015) 0.77
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A thin line between channels and pumps. Biophys J (2013) 0.75
In Vitro Activity of a Purified Natural Anion Channelrhodopsin. J Biol Chem (2016) 0.75
Adjacent channelrhodopsin-2 residues within transmembranes 2 and 7 regulate cation selectivity and distribution of the two open states. J Biol Chem (2017) 0.75
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Biophysical Properties of Optogenetic Tools and Their Application for Vision Restoration Approaches. Front Syst Neurosci (2016) 0.75
Kinetic characteristics of chimeric channelrhodopsins implicate the molecular identity involved in desensitization. Biophys Physicobiol (2017) 0.75
An Approach to Heterologous Expression of Membrane Proteins. The Case of Bacteriorhodopsin. PLoS One (2015) 0.75
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Optical Techniques in Optogenetics. J Mod Opt (2015) 0.75
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Neuroscience. Algae are the best engineers of optogenetic inhibitors. Nat Methods (2015) 0.75
The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance, and Spectral Sensitivity. Sci Rep (2017) 0.75
Bringing new dimensions to drug discovery screening: impact of cellular stimulation technologies. Drug Discov Today (2017) 0.75
An inhibitory role of Arg-84 in anion channelrhodopsin-2 expressed in Escherichia coli. Sci Rep (2017) 0.75
Molecular properties of a DTD channelrhodopsin from Guillardia theta. Biophys Physicobiol (2017) 0.75
Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach. PLoS One (2012) 0.75
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins. Proc Natl Acad Sci U S A (2017) 0.75
Optogenetics and its application in neural degeneration and regeneration. Neural Regen Res (2017) 0.75
Reaction dynamics of the chimeric channelrhodopsin C1C2. Sci Rep (2017) 0.75
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Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr Biol (2005) 8.01
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Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron (2006) 5.65
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Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophys J (2009) 4.75
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Ultra light-sensitive and fast neuronal activation with the Ca²+-permeable channelrhodopsin CatCh. Nat Neurosci (2011) 2.37
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Opto-current-clamp actuation of cortical neurons using a strategically designed channelrhodopsin. PLoS One (2010) 1.38
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