Published in Mutat Res on January 13, 2007
Evaluation of in vitro assays for assessing the toxicity of cigarette smoke and smokeless tobacco. Cancer Epidemiol Biomarkers Prev (2009) 1.30
In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity. Mutat Res (2007) 1.16
Genetic toxicology in the 21st century: reflections and future directions. Environ Mol Mutagen (2011) 1.12
Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. PLoS One (2011) 1.09
Synergistic metabolic toxicity screening using microsome/DNA electrochemiluminescent arrays and nanoreactors. Anal Chem (2008) 1.08
Look back in anger - what clinical studies tell us about preclinical work. ALTEX (2013) 1.04
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay. Mutat Res (2007) 1.00
The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century. Environ Health Perspect (2010) 1.00
A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells. BMC Cancer (2013) 0.92
Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Crit Rev Toxicol (2014) 0.90
Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects. Toxicol Sci (2009) 0.90
High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury. Toxicol Appl Pharmacol (2013) 0.80
Smarcal1 promotes double-strand-break repair by nonhomologous end-joining. Nucleic Acids Res (2015) 0.80
Comet assay in reconstructed 3D human epidermal skin models--investigation of intra- and inter-laboratory reproducibility with coded chemicals. Mutagenesis (2013) 0.78
The benzene metabolite para-benzoquinone is genotoxic in human, phorbol-12-acetate-13-myristate induced, peripheral blood mononuclear cells at low concentrations. Arch Toxicol (2009) 0.78
Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™). Part Fibre Toxicol (2016) 0.77
Trends in the study of genetic susceptibility. Interdiscip Toxicol (2008) 0.77
How accurate is in vitro prediction of carcinogenicity? Br J Pharmacol (2011) 0.76
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay. Environ Mol Mutagen (2017) 0.75
Critical role of toxicologic pathology in a short-term screen for carcinogenicity. J Toxicol Pathol (2016) 0.75
Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans. Biomed Res Int (2016) 0.75
The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency. Mutagenesis (2015) 0.75
Genotoxic mixtures and dissimilar action: concepts for prediction and assessment. Arch Toxicol (2013) 0.75
LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds. Cytotechnology (2016) 0.75
Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries. J Comput Aided Mol Des (2011) 0.75
Genome structure of the legume, Lotus japonicus. DNA Res (2008) 4.93
Universals and cultural variation in turn-taking in conversation. Proc Natl Acad Sci U S A (2009) 3.62
FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo. Blood (2011) 2.14
SQUAMOSA Promoter Binding Protein-Like7 Is a Central Regulator for Copper Homeostasis in Arabidopsis. Plant Cell (2009) 2.13
Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS Negl Trop Dis (2010) 2.08
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium. Nat Biotechnol (2010) 2.06
A comparison of mainstream and sidestream marijuana and tobacco cigarette smoke produced under two machine smoking conditions. Chem Res Toxicol (2007) 1.94
Plastid proteins crucial for symbiotic fungal and bacterial entry into plant roots. Nature (2004) 1.94
The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults. Front Cell Infect Microbiol (2013) 1.87
Distribution and characterization of peroxisomes in Arabidopsis by visualization with GFP: dynamic morphology and actin-dependent movement. Plant Cell Physiol (2002) 1.80
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO J (2004) 1.77
Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease. FASEB J (2007) 1.77
Hazardous compounds in tobacco smoke. Int J Environ Res Public Health (2011) 1.75
How many peas in a pod? Legume genes responsible for mutualistic symbioses underground. Plant Cell Physiol (2010) 1.74
The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans. J Biol Chem (2008) 1.74
NUCLEOPORIN85 is required for calcium spiking, fungal and bacterial symbioses, and seed production in Lotus japonicus. Plant Cell (2007) 1.71
The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance. Arch Toxicol (2011) 1.68
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Mol Cell Biol (2006) 1.63
MNT and MutaMouse studies to define the in vivo dose response relations of the genotoxicity of EMS and ENU. Toxicol Lett (2009) 1.60
CYCLOPS, a mediator of symbiotic intracellular accommodation. Proc Natl Acad Sci U S A (2008) 1.58
Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair. Hum Mol Genet (2007) 1.56
Large-scale analysis of gene expression profiles during early stages of root nodule formation in a model legume, Lotus japonicus. DNA Res (2004) 1.52
Cervical cancer in patients infected with the human immunodeficiency virus. Cancer (2008) 1.52
Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup. Mutat Res (2006) 1.51
A pilot study combining a GC-sensor device with a statistical model for the identification of bladder cancer from urine headspace. PLoS One (2013) 1.51
Prisons: mental health institutions of the 21st century? Med J Aust (2006) 1.48
Cytogenetic effects of hexavalent chromium in Bulgarian chromium platers. Mutat Res (2002) 1.48
Nuclear tau, a key player in neuronal DNA protection. J Biol Chem (2010) 1.47
Report from the in vitro micronucleus assay working group. Mutat Res (2003) 1.47
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. Arch Toxicol (2011) 1.46
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity. Mutat Res (2005) 1.45
Cardiac recovery in a human non-heart-beating donor after extracorporeal perfusion: source for human heart donation? J Heart Lung Transplant (2009) 1.45
Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis. FASEB J (2009) 1.44
Disability, employment and work performance among people with ICD-10 anxiety disorders. Aust N Z J Psychiatry (2005) 1.44
Steady-state solutions to PBPK models and their applications to risk assessment I: Route-to-route extrapolation of volatile chemicals. Risk Anal (2006) 1.44
Analysis of published data for top concentration considerations in mammalian cell genotoxicity testing. Mutagenesis (2010) 1.44
Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents. Toxicology (2004) 1.41
Evaluation of the GreenScreen GADD45alpha-GFP indicator assay with non-proprietary and proprietary compounds. Mutat Res (2008) 1.41
Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells. Environ Mol Mutagen (2008) 1.39
Cardiopulmonary reserve as determined by cardiopulmonary exercise testing correlates with length of stay and predicts complications after radical cystectomy. BJU Int (2015) 1.39
Expression islands clustered on the symbiosis island of the Mesorhizobium loti genome. J Bacteriol (2004) 1.39
A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery. Eur Arch Otorhinolaryngol (2013) 1.38
Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells. DNA Repair (Amst) (2007) 1.36
An Arabidopsis dynamin-related protein, DRP3A, controls both peroxisomal and mitochondrial division. Plant J (2004) 1.30
New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen (2010) 1.28
Nanos suppresses somatic cell fate in Drosophila germ line. Proc Natl Acad Sci U S A (2004) 1.27
CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4. Mol Biol Cell (2008) 1.27
A dominant function of CCaMK in intracellular accommodation of bacterial and fungal endosymbionts. Plant J (2010) 1.26
Towards consensus practices to qualify safety biomarkers for use in early drug development. Nat Biotechnol (2010) 1.25
Acupuncture analgesia: I. The scientific basis. Anesth Analg (2008) 1.25
Nodule inception directly targets NF-Y subunit genes to regulate essential processes of root nodule development in Lotus japonicus. PLoS Genet (2013) 1.24
Functional differentiation of peroxisomes revealed by expression profiles of peroxisomal genes in Arabidopsis thaliana. Plant Cell Physiol (2003) 1.23
Gibberellin controls the nodulation signaling pathway in Lotus japonicus. Plant J (2008) 1.23
The effectiveness of cognitive-behavioural interventions provided at Outlook: a disfigurement support unit. J Eval Clin Pract (2002) 1.22
Genetics of symbiosis in Lotus japonicus: recombinant inbred lines, comparative genetic maps, and map position of 35 symbiotic loci. Mol Plant Microbe Interact (2006) 1.21
Utility of recent studies to assess the National Research Council 2001 estimates of cancer risk from ingested arsenic. Environ Health Perspect (2010) 1.21
International study of factors affecting human chromosome translocations. Mutat Res (2008) 1.21
Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1. Cancer Res (2007) 1.21
CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation. Mol Cell Biol (2006) 1.20
Peroxisomes are required for in vivo nitric oxide accumulation in the cytosol following salinity stress of Arabidopsis plants. Plant Physiol (2009) 1.20
Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol (2004) 1.19
Highly oxidized peroxisomes are selectively degraded via autophagy in Arabidopsis. Plant Cell (2013) 1.18
The in vivo comet assay: use and status in genotoxicity testing. Mutagenesis (2005) 1.18
Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach. Mutat Res (2009) 1.17
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. J Clin Endocrinol Metab (2002) 1.16
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays. Mutat Res (2008) 1.16
Proteomic identification and characterization of a novel peroxisomal adenine nucleotide transporter supplying ATP for fatty acid beta-oxidation in soybean and Arabidopsis. Plant Cell (2008) 1.16
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*. ALTEX (2012) 1.15
Polycyclic aromatic hydrocarbons in foods: human exposure through the diet in Catalonia, Spain. J Food Prot (2003) 1.15
Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana. Plant Cell Physiol (2002) 1.14
Biomarkers. Mol Aspects Med (2002) 1.14
Variation in cadaveric organ donor rates in the UK. Nephrol Dial Transplant (2004) 1.13
Inter- and intraobserver assessment of periacetabular osteodensitometry after cemented and uncemented total hip arthroplasty using computed tomography. Arch Orthop Trauma Surg (2005) 1.11
Cytosolic HSP90 regulates the heat shock response that is responsible for heat acclimation in Arabidopsis thaliana. J Biol Chem (2007) 1.11
Novel glyoxysomal protein kinase, GPK1, identified by proteomic analysis of glyoxysomes in etiolated cotyledons of Arabidopsis thaliana. Plant Cell Physiol (2003) 1.11
Identification and localization of soluble sulfotransferases in the human gastrointestinal tract. Biochem J (2007) 1.11
Vitamin E activates gene expression via the pregnane X receptor. Biochem Pharmacol (2003) 1.11
SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. J Biol Chem (2008) 1.10
crinkle, a novel symbiotic mutant that affects the infection thread growth and alters the root hair, trichome, and seed development in Lotus japonicus. Plant Physiol (2003) 1.09
A peroxisomal ABC transporter promotes seed germination by inducing pectin degradation under the control of ABI5. Plant J (2010) 1.09
The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2. PLoS One (2009) 1.08
Traction on the cervix in theatre before anterior repair: Does it tell us when to perform a concomitant hysterectomy? Eur J Obstet Gynecol Reprod Biol (2011) 1.08
Functional classification of Arabidopsis peroxisome biogenesis factors proposed from analyses of knockdown mutants. Plant Cell Physiol (2007) 1.08
Direct interaction and determination of binding domains among peroxisomal import factors in Arabidopsis thaliana. Plant Cell Physiol (2002) 1.07
The utility of DNA microarrays for characterizing genotoxicity. Environ Health Perspect (2004) 1.07
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis. Eur J Med Chem (2011) 1.07
Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levels. Am J Pathol (2006) 1.07
High-sensitivity real-time imaging of dual protein-protein interactions in living subjects using multicolor luciferases. PLoS One (2009) 1.06
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells. Environ Mol Mutagen (2007) 1.05
CERBERUS, a novel U-box protein containing WD-40 repeats, is required for formation of the infection thread and nodule development in the legume-Rhizobium symbiosis. Plant J (2009) 1.05
A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana. Plant Cell Physiol (2008) 1.04
A modular approach to the ECVAM principles on test validity. Altern Lab Anim (2004) 1.04
Rhizobial and fungal symbioses show different requirements for calmodulin binding to calcium calmodulin-dependent protein kinase in Lotus japonicus. Plant Cell (2012) 1.04
Altered body image: appearance-related concerns of people with visible disfigurement. J Adv Nurs (2004) 1.04