Published in Anal Sci on February 01, 2007
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet (2010) 6.10
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature (2010) 5.43
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell (2010) 4.99
Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell (2012) 4.67
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med (2008) 3.64
c-kit and PDGFRA mutations in extragastrointestinal stromal tumor (gastrointestinal stromal tumor of the soft tissue). Am J Surg Pathol (2004) 2.46
TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies. Am J Surg Pathol (2007) 1.94
TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition. Cancer Res (2007) 1.93
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. J Clin Invest (2005) 1.88
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women. J Clin Oncol (2007) 1.66
Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade. J Am Soc Nephrol (2004) 1.61
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (2004) 1.58
High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway. Clin Cancer Res (2012) 1.56
Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertens Res (2007) 1.55
Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res (2010) 1.54
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54
Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis. J Am Soc Nephrol (2004) 1.53
Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol (2011) 1.50
ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor. Mol Cell Biol (2009) 1.46
Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells. J Cell Physiol (2006) 1.44
Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation. J Bone Miner Res (2004) 1.37
In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Dev Biol (2002) 1.27
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Mol Cell Biol (2011) 1.24
A novel transgenic mouse model to study the osteoblast lineage in vivo. Ann N Y Acad Sci (2007) 1.18
Nuclear expression of Y-box-binding protein-1 correlates with P-glycoprotein and topoisomerase II alpha expression, and with poor prognosis in synovial sarcoma. J Pathol (2003) 1.17
Identification of SCN3B as a novel p53-inducible proapoptotic gene. Oncogene (2004) 1.16
Malignant transformation of renal angiomyolipoma: a case report. Am J Surg Pathol (2002) 1.16
Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life. Proc Natl Acad Sci U S A (2010) 1.14
Radial augmentation index: a useful and easily obtainable parameter for vascular aging. Am J Hypertens (2005) 1.12
Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats. Neurosci Res (2006) 1.11
A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicits systemic humoral immunity in mice. Int Immunol (2004) 1.10
Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population. PLoS One (2013) 1.09
Multielement determination of trace metals in seawater by ICP-MS with aid of down-sized chelating resin-packed minicolumn for preconcentration. Talanta (2007) 1.09
Trophectoderm morphology significantly affects the rates of ongoing pregnancy and miscarriage in frozen-thawed single-blastocyst transfer cycle in vitro fertilization. Fertil Steril (2012) 1.06
Gamma knife stereotactic radiosurgery for atypical and malignant meningiomas. Acta Neurochir Suppl (2013) 1.03
ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis. PLoS One (2013) 1.03
Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss. PLoS One (2010) 1.03
Distinctive features of female-to-male transsexualism and prevalence of gender identity disorder in Japan. J Sex Med (2011) 1.02
Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization. Exp Cell Res (2005) 1.01
PDGF receptor alpha is an alternative mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma. Cancer Res (2012) 1.00
Multicenter phase II trial of weekly paclitaxel for advanced or metastatic breast cancer: the Saitama Breast Cancer Clinical Study Group (SBCCSG-01). Jpn J Clin Oncol (2003) 0.99
Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol (2009) 0.99
let-7 and miR-140 microRNAs coordinately regulate skeletal development. Proc Natl Acad Sci U S A (2013) 0.98
BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells. Cancer Lett (2011) 0.98
Japan Society of Gynecologic Oncology guidelines 2011 for the treatment of uterine cervical cancer. Int J Clin Oncol (2015) 0.97
Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model. Neurosci Res (2007) 0.94
Histopathological and ultrastructural features of Koi herpesvirus (KHV)-infected carp Cyprinus carpio, and the morphology and morphogenesis of KHV. Dis Aquat Organ (2008) 0.94
Beta-catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma. Arch Pathol Lab Med (2002) 0.94
DNA hypermethylation status of multiple genes in soft tissue sarcomas. Mod Pathol (2006) 0.94
Genetic and epigenetic alterations of the PTEN gene in soft tissue sarcomas. Hum Pathol (2005) 0.94
Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity. J Cancer Res Clin Oncol (2010) 0.93
Mechanisms of inactivation of the p16INK4a gene in leiomyosarcoma of soft tissue: decreased p16 expression correlates with promoter methylation and poor prognosis. J Pathol (2003) 0.93
Intraneural lipomatous tumor of the median nerve: Three case reports with a review of literature. Int J Surg Case Rep (2012) 0.92
Long-term outcomes in patients with vestibular schwannomas treated using gamma knife surgery: 10-year follow up. J Neurosurg (2005) 0.92
MicroRNAs involved in bone formation. Cell Mol Life Sci (2014) 0.92
Mitochondrial DNA analysis of Sporothrix schenckii from China, Korea and Spain. Nihon Ishinkin Gakkai Zasshi (2004) 0.92
Endoscopic incision for esophageal intramural hematoma after injection sclerotherapy: case report. Gastrointest Endosc (2003) 0.92
Sox9 is upstream of microRNA-140 in cartilage. Appl Biochem Biotechnol (2011) 0.92
Questionnaire survey of the current status of radical trachelectomy in Japan. Int J Clin Oncol (2010) 0.91
Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro. Endocrinology (2003) 0.91
Transplantation of olfactory mucosa following spinal cord injury promotes recovery in rats. Neuroreport (2008) 0.91
Association between polycystic ovary syndrome and female-to-male transsexuality. Hum Reprod (2006) 0.91
Hyperstimulation and a gonadotropin-releasing hormone agonist modulate ovarian vascular permeability by altering expression of the tight junction protein claudin-5. Endocrinology (2005) 0.91
Pregnancy-related complications after vaginal radical trachelectomy for early-stage invasive uterine cervical cancer. Int J Clin Oncol (2007) 0.91
Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase. J Pharm Pharmacol (2005) 0.91
Establishment of a quantitative ELISA for the measurement of allergen-specific IgE in dogs using anti-IgE antibody cross-reactive to mouse and dog IgE. Vet Immunol Immunopathol (2010) 0.90
Overexpression of HER2 signaling to WAVE2-Arp2/3 complex activates MMP-independent migration in breast cancer. Breast Cancer Res Treat (2010) 0.90
Death-associated protein kinase (DAP kinase) alteration in soft tissue leiomyosarcoma: Promoter methylation or homozygous deletion is associated with a loss of DAP kinase expression. Hum Pathol (2004) 0.90
Excessive androgen exposure in female-to-male transsexual persons of reproductive age induces hyperplasia of the ovarian cortex and stroma but not polycystic ovary morphology. Hum Reprod (2012) 0.90
Suppression of gap junctional intercellular communication via 5' CpG island methylation in promoter region of E-cadherin gene in endometrial cancer cells. Carcinogenesis (2003) 0.90
Stereotactic radiosurgery for metastatic tumors in the pituitary gland and the cavernous sinus. J Neurosurg (2006) 0.90
Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma. Oncol Rep (2011) 0.89
The role of CCR7 in allergic airway inflammation induced by house dust mite exposure. Cell Immunol (2012) 0.89
Mutation of beta-catenin gene in endometrial cancer but not in associated hyperplasia. Med Electron Microsc (2002) 0.89
MicroRNAs in cartilage development, homeostasis, and disease. Curr Osteoporos Rep (2014) 0.89
Stereotactic radiotherapy using Novalis for craniopharyngioma adjacent to optic pathways. J Neurooncol (2010) 0.88
Molecular analysis of p53, MDM2, and H-ras genes in osteosarcoma and malignant fibrous histiocytoma of bone in patients older than 40 years. Mod Pathol (2002) 0.88
Seasonal atopic dermatitis in dogs sensitive to a major allergen of Japanese cedar (Cryptomeria japonica) pollen. Vet Dermatol (2002) 0.88
Effect of demecolcine and nocodazole on the efficiency of chemically assisted removal of chromosomes and the developmental potential of nuclear transferred porcine oocytes. Cloning Stem Cells (2003) 0.88
Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features. Protein Expr Purif (2005) 0.88
Alteration in the Wnt/β-catenin signaling pathway in gastric neoplasias of fundic gland (chief cell predominant) type. Hum Pathol (2013) 0.88
Hemorrhagic shock 3 days after catheterization from the axillary vein. J Anesth (2010) 0.88
Complete anterior knee dislocation 16 years after cruciate-retaining total knee arthroplasty. Orthopedics (2012) 0.87
Cluster analysis of claudin-1 and -4, E-cadherin, and β-catenin expression in colorectal cancers. J Surg Oncol (2011) 0.87
Analysis of expressed sequence tags from Cryptomeria japonica pollen reveals novel pollen-specific transcripts. Tree Physiol (2006) 0.87
Increase of regulatory T cells and the ratio of specific IgE to total IgE are candidates for response monitoring or prognostic biomarkers in 2-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis. Clin Immunol (2011) 0.87
Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells. Int J Med Sci (2006) 0.87
Helicobacter pylori in patients receiving long-term dialysis. Am J Nephrol (2002) 0.87
Changed expression of heat shock proteins in various pathological findings in placentas with intrauterine fetal growth restriction. Med Electron Microsc (2004) 0.87
Angiotensin II type 1 receptor blockade attenuates renal fibrogenesis in an immune-mediated nephritic kidney through counter-activation of angiotensin II type 2 receptor. Biochem Biophys Res Commun (2004) 0.87
Prevalence of Helicobacter pylori antibodies in long-term dialysis patients. Nephrology (Carlton) (2004) 0.86
Hypermethylation in promoter region of retinoic acid receptor-beta gene and immunohistochemical findings on retinoic acid receptors in carcinogenesis of endometrium. Cancer Lett (2005) 0.86
Polycystic ovary syndrome is associated with genetic polymorphism in the insulin signaling gene IRS-1 but not ENPP1 in a Japanese population. Life Sci (2007) 0.86
The induced regulatory T cell level, defined as the proportion of IL-10(+)Foxp3(+) cells among CD25(+)CD4(+) leukocytes, is a potential therapeutic biomarker for sublingual immunotherapy: a preliminary report. Int Arch Allergy Immunol (2010) 0.86
Trigeminal neuralgia caused by nerve compression by dilated superior cerebellar artery associated with cerebellar arteriovenous malformation: case report. Neurol Med Chir (Tokyo) (2013) 0.86
Selective depletion of fibroblasts preserves morphology and the functional integrity of peritoneum in transgenic mice with peritoneal fibrosing syndrome. Kidney Int (2003) 0.86