Published in JAMA on February 14, 2007
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36
Relation of iron and red meat intake to blood pressure: cross sectional epidemiological study. BMJ (2008) 2.09
Examining the evidence: a systematic review of the inclusion and analysis of older adults in randomized controlled trials. J Gen Intern Med (2011) 1.92
Iron and thrombosis. Ann Hematol (2007) 1.43
Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial. BMC Med (2012) 1.40
Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients. Diabetes Care (2008) 1.14
Enigmatic sex disparities in cancer incidence. Eur J Epidemiol (2012) 1.14
Iron and menopause: does increased iron affect the health of postmenopausal women? Antioxid Redox Signal (2009) 1.12
The association of biomarkers of iron status with mortality in US adults. Nutr Metab Cardiovasc Dis (2011) 1.07
Excessive body iron stores are not associated with risk of coronary heart disease in women. J Nutr (2008) 0.98
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice. Exp Biol Med (Maywood) (2010) 0.93
Iron status is associated with carotid atherosclerotic plaques in middle-aged adults. J Nutr (2010) 0.92
Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. Am J Nephrol (2011) 0.92
Iron deficiency in whole blood donors. Transfusion (2011) 0.92
Iron, meat and health. Nutrients (2011) 0.92
Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes. PLoS One (2016) 0.91
Iron and thiols as two major players in carcinogenesis: friends or foes? Front Pharmacol (2014) 0.91
Atherogenesis and iron: from epidemiology to cellular level. Front Pharmacol (2014) 0.87
Dietary intake of minerals and the risk of ischemic stroke in Guangdong Province, China, 2007-2008. Prev Chronic Dis (2011) 0.87
Iron: protector or risk factor for cardiovascular disease? Still controversial. Nutrients (2013) 0.86
The iron-heart hypothesis: search for the ironclad evidence. JAMA (2007) 0.85
Ferritin couples iron and fatty acid metabolism. FASEB J (2012) 0.83
The association of biomarkers of iron status with peripheral arterial disease in US adults. BMC Cardiovasc Disord (2009) 0.82
Treatment of anemia in heart failure: potential risks and benefits of intravenous iron therapy in cardiovascular disease. Cardiol Rev (2010) 0.82
The statin-iron nexus: anti-inflammatory intervention for arterial disease prevention. Am J Public Health (2013) 0.81
Design and Rationale for the Study of Changes in Iron and Atherosclerosis Risk in Perimenopause. J Clin Exp Cardiolog (2011) 0.79
Oral contraceptive use, iron stores and vascular endothelial function in healthy women. Contraception (2011) 0.78
Iron and noncontrast magnetic resonance T2* as a marker of intraplaque iron in human atherosclerosis. J Vasc Surg (2014) 0.78
Iron and atherosclerosis: nailing down a novel target with magnetic resonance. J Cardiovasc Transl Res (2014) 0.78
Iron reduction and cardiovascular outcomes. JAMA (2007) 0.78
A U-shaped relationship between haematocrit and mortality in a large prospective cohort study. Int J Epidemiol (2013) 0.78
Iron deficiency anemia in heart failure. Heart Fail Rev (2013) 0.78
Getting the iron out: phlebotomy for Alzheimer's disease? Med Hypotheses (2009) 0.77
Suppression of SLC11A2 expression is essential to maintain duodenal integrity during dietary iron overload. Am J Pathol (2010) 0.77
HFE gene mutations increase the risk of coronary heart disease in women. Eur J Epidemiol (2010) 0.76
Targets for adapting intravenous iron dose in hemodialysis: a proof of concept study. BMC Nephrol (2017) 0.75
Vascular Damage in Patients with Nonalcoholic Fatty Liver Disease: Possible Role of Iron and Ferritin. Int J Mol Sci (2016) 0.75
Dietary intake of minerals in the patients with stroke. J Res Med Sci (2013) 0.75
The big idea: the coxib crisis iron, aspirin and heart disease risk revisited. J R Soc Med (2007) 0.75
Iron reduction and cardiovascular outcomes. JAMA (2007) 0.75
Initial serum ferritin predicts number of therapeutic phlebotomies to iron depletion in secondary iron overload. Transfusion (2014) 0.75
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med (2005) 15.46
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry (2006) 12.41
Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ (2010) 10.85
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA (2007) 7.93
A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N Engl J Med (2003) 6.99
Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design. Control Clin Trials (2004) 6.64
Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement. Lancet Oncol (2009) 5.05
Background and rationale for the sequenced treatment alternatives to relieve depression (STAR*D) study. Psychiatr Clin North Am (2003) 5.05
Association between hospital and surgeon procedure volume and the outcomes of total knee replacement. J Bone Joint Surg Am (2004) 4.42
Rates and outcomes of primary and revision total hip replacement in the United States medicare population. J Bone Joint Surg Am (2003) 4.38
Colorectal cancer in patients under close colonoscopic surveillance. Gastroenterology (2005) 4.31
Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol (2012) 4.22
A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med (2001) 4.07
Translating the Diabetes Prevention Program lifestyle intervention for weight loss into primary care: a randomized trial. JAMA Intern Med (2013) 3.69
Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study. Lancet (2007) 3.66
Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial. JAMA (2007) 3.66
Shared treatment decision making improves adherence and outcomes in poorly controlled asthma. Am J Respir Crit Care Med (2009) 3.65
Frequency of stress testing to document ischemia prior to elective percutaneous coronary intervention. JAMA (2008) 3.62
Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial. J Natl Cancer Inst (2003) 3.44
Incidence rates of dislocation, pulmonary embolism, and deep infection during the first six months after elective total hip replacement. J Bone Joint Surg Am (2003) 3.33
American Society of Echocardiography recommendations for quality echocardiography laboratory operations. J Am Soc Echocardiogr (2011) 3.32
Constipation and a low-fiber diet are not associated with diverticulosis. Clin Gastroenterol Hepatol (2013) 3.31
Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials. J Natl Cancer Inst (2009) 3.15
Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. Am J Clin Nutr (2007) 3.14
Physical activity and survival after diagnosis of invasive breast cancer. Cancer Epidemiol Biomarkers Prev (2008) 3.11
Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome. J Natl Cancer Inst (2013) 3.06
Association of hospital and surgeon volume of total hip replacement with functional status and satisfaction three years following surgery. Arthritis Rheum (2003) 2.98
Identification of Lynch syndrome among patients with colorectal cancer. JAMA (2012) 2.77
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A (2006) 2.72
Accuracy of Medicare claims data for rheumatologic diagnoses in total hip replacement recipients. J Clin Epidemiol (2003) 2.72
The relation between patients' outcomes and the volume of cardioverter-defibrillator implantation procedures performed by physicians treating Medicare beneficiaries. J Am Coll Cardiol (2005) 2.71
One-year risk for advanced colorectal neoplasia: U.S. versus U.K. risk-stratification guidelines. Ann Intern Med (2012) 2.70
Epidemiology of total knee replacement in the United States Medicare population. J Bone Joint Surg Am (2005) 2.67
Folic acid and risk of prostate cancer: results from a randomized clinical trial. J Natl Cancer Inst (2009) 2.64
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology (2012) 2.57
Risks of Lynch syndrome cancers for MSH6 mutation carriers. J Natl Cancer Inst (2009) 2.56
A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy. Gastroenterology (2008) 2.56
The care of patients with an abdominal aortic aneurysm: the Society for Vascular Surgery practice guidelines. J Vasc Surg (2009) 2.51
Prevalence of alterations in DNA mismatch repair genes in patients with young-onset colorectal cancer. Clin Gastroenterol Hepatol (2010) 2.50
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet (2009) 2.50
Colorectal cancers soon after colonoscopy: a pooled multicohort analysis. Gut (2013) 2.50
Alcohol consumption before and after breast cancer diagnosis: associations with survival from breast cancer, cardiovascular disease, and other causes. J Clin Oncol (2013) 2.46
Long-term outcomes of endoscopic vein harvesting after coronary artery bypass grafting. Circulation (2011) 2.44
Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study. Gastroenterology (2007) 2.39
Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Lancet (2013) 2.37
Randomized trial of trauma-focused group therapy for posttraumatic stress disorder: results from a department of veterans affairs cooperative study. Arch Gen Psychiatry (2003) 2.32
Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery. Gut (2010) 2.30
Serious renal dysfunction after percutaneous coronary interventions can be predicted. Am Heart J (2007) 2.30
Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol (2012) 2.22
SVS practice guidelines for the care of patients with an abdominal aortic aneurysm: executive summary. J Vasc Surg (2009) 2.16
Telomere length varies by DNA extraction method: implications for epidemiologic research. Cancer Epidemiol Biomarkers Prev (2013) 2.14
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev (2008) 2.12
Decreased cancer risk after iron reduction in patients with peripheral arterial disease: results from a randomized trial. J Natl Cancer Inst (2008) 2.11
Development of common data elements: the experience of and recommendations from the early detection research network. Int J Med Inform (2003) 2.04
Aspirin in the chemoprevention of colorectal neoplasia: an overview. Cancer Prev Res (Phila) (2011) 2.03
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res (2007) 2.02
Effect of prior cardiac operations on survival after coronary artery bypass grafting. Ann Thorac Surg (2011) 2.02
Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. J Natl Cancer Inst (2010) 1.99
Flow loading induces macrophage antioxidative gene expression in experimental aneurysms. Arterioscler Thromb Vasc Biol (2002) 1.96
Outcomes of percutaneous coronary interventions performed at centers without and with onsite coronary artery bypass graft surgery. JAMA (2004) 1.94
Survival after hip fracture. Osteoporos Int (2005) 1.93
A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen. Clin Trials (2011) 1.91
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev (2009) 1.88
Prediction of survival after coronary revascularization: modeling short-term, mid-term, and long-term survival. Ann Thorac Surg (2009) 1.86
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J Clin Invest (2012) 1.84
Recurrence of bipolar disorders and major depression. A life-long perspective. Eur Arch Psychiatry Clin Neurosci (2003) 1.82
Diversity of lipid mediators in human adipose tissue depots. Am J Physiol Cell Physiol (2013) 1.80
Association of hospital and surgeon procedure volume with patient-centered outcomes of total knee replacement in a population-based cohort of patients age 65 years and older. Arthritis Rheum (2007) 1.78
Translating research into practice: organizational issues in implementing automated decision support for hypertension in three medical centers. J Am Med Inform Assoc (2004) 1.75
Variability in surgeons' perioperative practices may influence the incidence of low-output failure after coronary artery bypass grafting surgery. Circ Cardiovasc Qual Outcomes (2012) 1.74
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion. Sci Transl Med (2012) 1.73
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial. J Natl Cancer Inst (2007) 1.73
Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. JAMA (2008) 1.73
Risk prediction of 30-day readmission after infrainguinal bypass for critical limb ischemia. J Vasc Surg (2013) 1.72
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status. Cancer Epidemiol Biomarkers Prev (2009) 1.72
Characteristics and survival of interval and sporadic colorectal cancer patients: a nationwide population-based cohort study. Am J Gastroenterol (2013) 1.71
The cognitive effects of electroconvulsive therapy in community settings. Neuropsychopharmacology (2006) 1.71
Integrating tobacco cessation into mental health care for posttraumatic stress disorder: a randomized controlled trial. JAMA (2010) 1.71
Thromboembolic risk among Danish children and adults with inflammatory bowel diseases: a population-based nationwide study. Gut (2011) 1.70
Metabolic tumor burden predicts for disease progression and death in lung cancer. Int J Radiat Oncol Biol Phys (2007) 1.69
Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol (2013) 1.68
Effect of calcium supplementation on the risk of large bowel polyps. J Natl Cancer Inst (2004) 1.67
Transient and persistent renal dysfunction are predictors of survival after percutaneous coronary intervention: insights from the Dartmouth Dynamic Registry. Catheter Cardiovasc Interv (2008) 1.67
Medical management of small abdominal aortic aneurysms. Circulation (2008) 1.67
Twelve-year risk of revision after primary total hip replacement in the U.S. Medicare population. J Bone Joint Surg Am (2012) 1.67
Colon and rectal cancer survival by tumor location and microsatellite instability: the Colon Cancer Family Registry. Dis Colon Rectum (2013) 1.65
Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. Cancer Prev Res (Phila) (2012) 1.65
Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. PLoS Genet (2012) 1.64
Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr (2010) 1.64
Ferritin levels, inflammatory biomarkers, and mortality in peripheral arterial disease: a substudy of the Iron (Fe) and Atherosclerosis Study (FeAST) Trial. J Vasc Surg (2010) 1.62