Published in J Gen Intern Med on February 01, 2011
The Treatment of Primary Breast Cancer in Older Women With Adjuvant Therapy: A Retrospective Analysis of Data From Over 3000 Patients From the PATH Biobank, With Two-Year Follow-up. Dtsch Arztebl Int (2015) 2.35
Understanding the context of health for persons with multiple chronic conditions: moving from what is the matter to what matters. Ann Fam Med (2014) 1.73
MRI-measured regression of carotid atherosclerosis induced by statins with and without niacin in a randomised controlled trial: the NIA plaque study. Heart (2013) 1.50
A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity. J Gen Intern Med (2014) 1.46
Quality of care for patients with multiple chronic conditions: the role of comorbidity interrelatedness. J Gen Intern Med (2013) 1.45
Deprescribing medication in very elderly patients with multimorbidity: the view of Dutch GPs. A qualitative study. BMC Fam Pract (2012) 1.35
Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them. Pain Med (2011) 1.25
Retracted Breast cancer surgery in elderly patients: postoperative complications and survival. BMC Surg (2013) 1.12
Informing evidence-based decision-making for patients with comorbidity: availability of necessary information in clinical trials for chronic diseases. PLoS One (2012) 1.05
Strategies and Challenges in Clinical Trials Targeting Human Aging. J Gerontol A Biol Sci Med Sci (2016) 1.01
Polypharmacy and excessive polypharmacy in octogenarians and older acutely hospitalized patients. Wien Klin Wochenschr (2014) 0.99
IOM and DHHS meeting on making clinical practice guidelines appropriate for patients with multiple chronic conditions. Ann Fam Med (2014) 0.99
Addressing multimorbidity in evidence integration and synthesis. J Gen Intern Med (2014) 0.98
Multiple myeloma in the older adult: better prospects, more challenges. J Clin Oncol (2014) 0.95
What are priorities for deprescribing for elderly patients? Capturing the voice of practitioners: a modified delphi process. PLoS One (2015) 0.94
A framework for the analysis of heterogeneity of treatment effect in patient-centered outcomes research. J Clin Epidemiol (2013) 0.94
Chemotherapy for colorectal cancer in the elderly. World J Gastroenterol (2015) 0.93
Road map to a patient-centered research agenda at the intersection of hospital medicine and geriatric medicine. J Gen Intern Med (2014) 0.93
Validation of a Prediction Tool for Chemotherapy Toxicity in Older Adults With Cancer. J Clin Oncol (2016) 0.91
Personalized surgical management of colorectal cancer in elderly population. World J Gastroenterol (2014) 0.91
Treatment of colorectal cancer in older patients. Nat Rev Gastroenterol Hepatol (2012) 0.89
Making general internal medicine research relevant to the older patient with multiple chronic comorbidities. J Gen Intern Med (2014) 0.86
How does a clinical trial fit into the real world? The RELAX-AHF study population into the EAHFE registry. Clin Res Cardiol (2015) 0.85
Development and pilot testing of a decision aid for drivers with dementia. BMC Med Inform Decis Mak (2014) 0.85
Delivering a "dose of hope": a faith-based program to increase older african americans' participation in clinical trials. JMIR Res Protoc (2015) 0.83
Induction with interleukin-2 antagonist for transplantation of kidneys from older deceased donors: an observational study. Transplant Res (2013) 0.82
Treatment of older patients with colorectal cancer: a perspective review. Ther Adv Med Oncol (2014) 0.81
A Rationale for Age-Adapted Immunosuppression in Organ Transplantation. Transplantation (2015) 0.81
Taking Healthy Steps: rationale, design and baseline characteristics of a randomized trial of a pedometer-based Internet-mediated walking program in veterans with chronic obstructive pulmonary disease. BMC Pulm Med (2014) 0.81
Caring for patients with kidney disease: shifting the paradigm from evidence-based medicine to patient-centered care. Nephrol Dial Transplant (2015) 0.81
Research priorities in geriatric palliative care: multimorbidity. J Palliat Med (2013) 0.80
Expert consensus panel guidelines on geriatric assessment in oncology. Eur J Cancer Care (Engl) (2015) 0.80
Inclusion and analysis of older adults in RCTs. J Gen Intern Med (2011) 0.79
Illness representations of restricting back pain: the older Person’s perspective. Pain Med (2014) 0.79
Movement disorders in elderly users of risperidone and first generation antipsychotic agents: a Canadian population-based study. PLoS One (2013) 0.78
Older patients with breast cancer: is there bias in the treatment they receive? Ther Adv Med Oncol (2012) 0.78
Innovating aging: promises and pitfalls on the road to life extension. Gerontology (2014) 0.77
[Safety of antirheumatic drug treatment in the elderly]. Z Rheumatol (2014) 0.77
Research priorities in geriatric palliative care: nonpain symptoms. J Palliat Med (2013) 0.76
Older Adults Reporting More Diabetes Mellitus Care Have Greater 9-Year Survival. J Am Geriatr Soc (2015) 0.76
Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study. Biomed Res Int (2016) 0.75
Statinopause. J Gen Intern Med (2014) 0.75
External validity of randomized controlled trials in older adults, a systematic review. PLoS One (2017) 0.75
Bisphosphonates for Osteoporosis in Patients with Renal Insufficiency: Pharmacists' Practices and Beliefs. Can J Hosp Pharm (2016) 0.75
Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer. Cancers (Basel) (2016) 0.75
Quality care provision for older people: an interview study with patients and primary healthcare professionals. Br J Gen Pract (2015) 0.75
Correlation of Incident Potentially Inappropriate Medication Prescriptions and Hospitalization: An Analysis Based on the PRISCUS List. Drugs Real World Outcomes (2015) 0.75
Development of a core outcome set for medication review in older patients with multimorbidity and polypharmacy: a study protocol. Clin Interv Aging (2017) 0.75
Missed Opportunities for Loco-Regional Treatment of Elderly Women with Breast Cancer. World J Surg (2016) 0.75
Attitudes of Surgeons toward Elderly Cancer Patients: A Survey from the SIOG Surgical Task Force. Visc Med (2017) 0.75
Harnessing Implementation Science to Increase the Impact of Health Equity Research. Med Care (2017) 0.75
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet (2002) 44.28
The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med (2001) 37.70
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med (2009) 35.37
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet (2001) 31.74
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med (2007) 24.19
Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med (2010) 21.49
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med (2007) 20.19
Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med (2007) 17.85
Participation in cancer clinical trials: race-, sex-, and age-based disparities. JAMA (2004) 14.05
Statistics in medicine--reporting of subgroup analyses in clinical trials. N Engl J Med (2007) 12.55
Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med (1999) 11.44
Subgroup analysis and other (mis)uses of baseline data in clinical trials. Lancet (2000) 9.80
Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet (2007) 9.23
Statistical problems in the reporting of clinical trials. A survey of three medical journals. N Engl J Med (1987) 8.64
Dichotomizing continuous predictors in multiple regression: a bad idea. Stat Med (2006) 8.25
Subgroup analysis, covariate adjustment and baseline comparisons in clinical trial reporting: current practice and problems. Stat Med (2002) 7.41
Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med (2007) 6.72
Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial. JAMA (2007) 6.25
Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review. JAMA (2007) 6.09
Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. JAMA (1991) 6.05
Treating individuals 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation. Lancet (2005) 5.94
Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol (2003) 4.77
Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA (2001) 4.28
Lack of benefit for intravenous thrombolysis in patients with myocardial infarction who are older than 75 years. Circulation (2000) 4.06
Subgroup analyses in randomized trials: risks of subgroup-specific analyses; power and sample size for the interaction test. J Clin Epidemiol (2004) 3.93
Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses. BMJ (2010) 3.54
Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials (2010) 3.45
Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: a randomized controlled trial. JAMA (2007) 3.44
Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure. Am Heart J (2003) 3.11
Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis. BMC Med Res Methodol (2006) 2.27
Including older people in clinical research. BMJ (2005) 2.01
Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: is the evidence base relevant to older adults? Ann Intern Med (2009) 1.98
Treating individuals 3: from subgroups to individuals: general principles and the example of carotid endarterectomy. Lancet (2005) 1.96
Caring for older Americans: the future of geriatric medicine. J Am Geriatr Soc (2005) 1.82
Subgroup analyses in therapeutic cardiovascular clinical trials: are most of them misleading? Am Heart J (2006) 1.48
Cautionary tales in the interpretation of clinical studies involving older persons. Arch Intern Med (2010) 1.20
Subgroups, treatment effects, and baseline risks: some lessons from major cardiovascular trials. Am Heart J (2000) 1.20
Prevalence and predictors of research participant eligibility criteria in alcohol treatment outcome studies, 1970-98. Addiction (2005) 1.14
U.S. Health spending by age, selected years through 2004. Health Aff (Millwood) (2007) 1.09
Diabetes and cardiovascular disease prevention in older adults. Clin Geriatr Med (2009) 1.08
Comparison of quality of care for patients in the Veterans Health Administration and patients in a national sample. Ann Intern Med (2004) 6.86
Duration of resuscitation efforts and survival after in-hospital cardiac arrest: an observational study. Lancet (2012) 6.60
Limitations of applying summary results of clinical trials to individual patients: the need for risk stratification. JAMA (2007) 5.60
The relative importance of physician communication, participatory decision making, and patient understanding in diabetes self-management. J Gen Intern Med (2002) 4.79
A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis. N Engl J Med (2012) 4.51
Treatment of hypertension in type 2 diabetes mellitus: blood pressure goals, choice of agents, and setting priorities in diabetes care. Ann Intern Med (2003) 3.81
Adherence to colorectal cancer screening: a randomized clinical trial of competing strategies. Arch Intern Med (2012) 3.79
Lessons from the mammography wars. N Engl J Med (2010) 3.68
Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials (2010) 3.45
Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J Gerontol A Biol Sci Med Sci (2009) 3.14
Are bad outcomes from questionable clinical decisions preventable medical errors? A case of cascade iatrogenesis. Ann Intern Med (2002) 3.07
Mechanisms for racial and ethnic disparities in glycemic control in middle-aged and older Americans in the health and retirement study. Arch Intern Med (2007) 3.05
Racial disparities in diabetes care processes, outcomes, and treatment intensity. Med Care (2003) 2.88
Patients, privacy and trust: patients' willingness to allow researchers to access their medical records. Soc Sci Med (2006) 2.86
Building a better quality measure: are some patients with 'poor quality' actually getting good care? Med Care (2003) 2.85
Accepting critically ill transfer patients: adverse effect on a referral center's outcome and benchmark measures. Ann Intern Med (2003) 2.75
Pharmacologic lipid-lowering therapy in type 2 diabetes mellitus: background paper for the American College of Physicians. Ann Intern Med (2004) 2.73
Whom should we profile? Examining diabetes care practice variation among primary care providers, provider groups, and health care facilities. Health Serv Res (2002) 2.68
Geriatric conditions and disability: the Health and Retirement Study. Ann Intern Med (2007) 2.62
Beyond the randomized clinical trial: the role of effectiveness studies in evaluating cardiovascular therapies. Circulation (2008) 2.45
Case management for patients with poorly controlled diabetes: a randomized trial. Am J Med (2004) 2.41
Brief report: the burden of diabetes therapy: implications for the design of effective patient-centered treatment regimens. J Gen Intern Med (2005) 2.32
Predictors of physician career satisfaction, work-life balance, and burnout. Obstet Gynecol (2007) 2.25
An IV for the RCT: using instrumental variables to adjust for treatment contamination in randomised controlled trials. BMJ (2010) 2.22
Uninsured adults presenting to US emergency departments: assumptions vs data. JAMA (2008) 2.15
Evidence-based risk communication: a systematic review. Ann Intern Med (2014) 2.14
Effect of perioperative statins on death, myocardial infarction, atrial fibrillation, and length of stay: a systematic review and meta-analysis. Arch Surg (2012) 2.12
Variation in the net benefit of aggressive cardiovascular risk factor control across the US population of patients with diabetes mellitus. Arch Intern Med (2010) 2.06
Progression risk, urinary protein excretion, and treatment effects of angiotensin-converting enzyme inhibitors in nondiabetic kidney disease. J Am Soc Nephrol (2007) 2.00
Impact of the model for end-stage liver disease allocation policy on the use of high-risk organs for liver transplantation. Gastroenterology (2008) 1.95
How well do patients' assessments of their diabetes self-management correlate with actual glycemic control and receipt of recommended diabetes services? Diabetes Care (2003) 1.81
Does physician communication influence older patients' diabetes self-management and glycemic control? Results from the Health and Retirement Study (HRS). J Gerontol A Biol Sci Med Sci (2007) 1.80
Performance measurement in search of a path. N Engl J Med (2007) 1.78
The impact of diabetes on workforce participation: results from a national household sample. Health Serv Res (2004) 1.70
Comparing models of frailty: the Health and Retirement Study. J Am Geriatr Soc (2009) 1.69
Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease. Circulation (2007) 1.68
Specialty care and the patient-centered medical home. Med Care (2011) 1.68
Setting eligibility criteria for a care-coordination benefit. J Am Geriatr Soc (2005) 1.67
Proactive case management of high-risk patients with type 2 diabetes mellitus by a clinical pharmacist: a randomized controlled trial. Am J Manag Care (2005) 1.64
What causes pregnancy loss? Preexisting mental illness as an independent risk factor. Gen Hosp Psychiatry (2007) 1.63
All-or-nothing treatment targets make bad performance measures. Am J Manag Care (2007) 1.61
Marriage and cohabitation outcomes after pregnancy loss. Pediatrics (2010) 1.61
New diabetes HEDIS blood pressure quality measure: potential for overtreatment. Am J Manag Care (2010) 1.60
When there is too much to do: how practicing physicians prioritize among recommended interventions. J Gen Intern Med (2004) 1.53
Open-access electronic case report journals: the rationale for case report guidelines. J Clin Epidemiol (2013) 1.51
Comparing clinical automated, medical record, and hybrid data sources for diabetes quality measures. Jt Comm J Qual Improv (2002) 1.48
Chronic obstructive pulmonary disease, cognitive impairment, and development of disability: the health and retirement study. Ann Am Thorac Soc (2014) 1.44
Shifting views on lipid lowering therapy. BMJ (2010) 1.44
Effect of flexible sigmoidoscopy-based screening on incidence and mortality of colorectal cancer: a systematic review and meta-analysis of randomized controlled trials. PLoS Med (2012) 1.38
Degree of disability and patterns of caregiving among older Americans with congestive heart failure. J Gen Intern Med (2007) 1.32
Interhospital transfers among Medicare beneficiaries admitted for acute myocardial infarction at nonrevascularization hospitals. Circ Cardiovasc Qual Outcomes (2010) 1.31
Patient-centered performance management: enhancing value for patients and health care systems. JAMA (2013) 1.29
CKD progression and mortality among older patients with diabetes. Am J Kidney Dis (2005) 1.24
Prevalence, diagnosis, and treatment of impaired fasting glucose and impaired glucose tolerance in nondiabetic U.S. adults. Diabetes Care (2010) 1.23
The rheumatoid hand: a predictable disease with unpredictable surgical practice patterns. Arthritis Rheum (2002) 1.20
Clinical complexity in middle-aged and older adults with diabetes: the Health and Retirement Study. Med Care (2010) 1.14
Informal caregiving for diabetes and diabetic complications among elderly americans. J Gerontol B Psychol Sci Soc Sci (2002) 1.13
Geriatric conditions develop in middle-aged adults with diabetes. J Gen Intern Med (2010) 1.13
Individual and population benefits of daily aspirin therapy: a proposal for personalizing national guidelines. Circ Cardiovasc Qual Outcomes (2011) 1.11
The relative merits of population-based and targeted prevention strategies. Milbank Q (2008) 1.10
The effect of diabetes on disability in middle-aged and older adults. J Gerontol A Biol Sci Med Sci (2005) 1.09
Improving eye care for veterans with diabetes: an example of using the QUERI steps to move from evidence to implementation: QUERI Series. Implement Sci (2008) 1.09
Diabetes and cardiovascular disease prevention in older adults. Clin Geriatr Med (2009) 1.08
Physical activity and mortality across cardiovascular disease risk groups. Med Sci Sports Exerc (2004) 1.07
Blood pressure trajectories prior to death in patients with diabetes. Diabetes Care (2011) 1.07
Quality by any other name?: a comparison of three profiling systems for assessing health care quality. Health Serv Res (2007) 1.07
Using internally developed risk models to assess heterogeneity in treatment effects in clinical trials. Circ Cardiovasc Qual Outcomes (2014) 1.07
Management of diabetes mellitus in older adults: are national guidelines appropriate? J Am Geriatr Soc (2002) 1.06
The association between three different measures of health status and satisfaction among patients with diabetes. Med Care Res Rev (2003) 1.06
Access to clinically-detailed patient information: a fundamental element for improving the efficiency and quality of healthcare. Med Care (2008) 1.05
Prematurity and low birth weight as potential mediators of higher stillbirth risk in mixed black/white race couples. J Womens Health (Larchmt) (2010) 1.02
Improved cardiovascular risk prediction using nonparametric regression and electronic health record data. Med Care (2013) 1.02
Physician-level P4P--DOA? Can quality-based payment be resuscitated? Am J Manag Care (2007) 1.01
Competing risk and heterogeneity of treatment effect in clinical trials. Trials (2008) 1.01
Performance measurement in chronic kidney disease. J Am Soc Nephrol (2011) 1.01
Can school income and racial/ethnic composition explain the racial/ethnic disparity in adolescent physical activity participation? Pediatrics (2006) 1.00
Patterns of disability related to diabetes mellitus in older women. J Gerontol A Biol Sci Med Sci (2004) 0.99
Hyperglycemia and incidence of frailty and lower extremity mobility limitations in older women. J Am Geriatr Soc (2012) 0.99
Low micronutrient levels as a predictor of incident disability in older women. Arch Intern Med (2006) 0.97
Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging. Biomacromolecules (2009) 0.97
Does rectal indomethacin eliminate the need for prophylactic pancreatic stent placement in patients undergoing high-risk ERCP? Post hoc efficacy and cost-benefit analyses using prospective clinical trial data. Am J Gastroenterol (2013) 0.96
Diminishing efficacy of combination therapy, response-heterogeneity, and treatment intolerance limit the attainability of tight risk factor control in patients with diabetes. Health Serv Res (2010) 0.95
Physician perceptions of upper extremity reconstruction for the person with tetraplegia. J Hand Surg Am (2005) 0.94
Prevalence of cognitive impairment in older adults with heart failure. J Am Geriatr Soc (2012) 0.92
How physicians cope with stillbirth or neonatal death: a national survey of obstetricians. Obstet Gynecol (2008) 0.90
Fall-associated difficulty with activities of daily living in functionally independent individuals aged 65 to 69 in the United States: a cohort study. J Am Geriatr Soc (2013) 0.89
Effectiveness of implantable cardioverter-defibrillators in patients with ischemic heart disease and left ventricular dysfunction. Arch Intern Med (2006) 0.89
Counting deaths due to medical errors. JAMA (2002) 0.89
Physical function limitations among middle-aged and older adults with prediabetes: one exercise prescription may not fit all. Diabetes Care (2013) 0.88
Physician practices and readiness for medical home reforms: policy, pitfalls, and possibilities. Health Serv Res (2011) 0.88
Profiling quality of care: Is there a role for peer review? BMC Health Serv Res (2004) 0.87
Tissue plasminogen activator was cost-effective compared to streptokinase in only selected patients with acute myocardial infarction. J Clin Epidemiol (2004) 0.87
Clinical complexity and mortality in middle-aged and older adults with diabetes. J Gerontol A Biol Sci Med Sci (2012) 0.87
Influence of study sponsorship on head and neck cancer randomized trial results. Head Neck (2012) 0.87
Improving the reliability of physician "report cards". Med Care (2013) 0.86