Published in J Biol Chem on February 19, 2007
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Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis. J Biol Chem (2014) 0.81
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Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause release of cytochrome c from vesicles. FEBS Lett (2007) 0.81
Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci Signal (2015) 0.80
Fine Tuning of a Type 1 Interferon Antagonist. PLoS One (2015) 0.79
Production and characterization of thirteen human type-I interferon-α subtypes. Protein Expr Purif (2014) 0.79
Type I interferons in viral control and immune regulation. Curr Opin Virol (2016) 0.78
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A potent in vivo anti-tumor efficacy of novel recombinant type I interferon. Clin Cancer Res (2016) 0.76
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ProMate: a structure based prediction program to identify the location of protein-protein binding sites. J Mol Biol (2004) 3.18
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Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details. Protein Eng Des Sel (2009) 2.25
Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta. Mol Cell Biol (2006) 1.82
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions. Methods (2012) 1.75
The molecular architecture of protein-protein binding sites. Curr Opin Struct Biol (2007) 1.59
Protein-protein association in polymer solutions: from dilute to semidilute to concentrated. Biophys J (2006) 1.40
Community-wide assessment of protein-interface modeling suggests improvements to design methodology. J Mol Biol (2011) 1.40
Separating the contribution of translational and rotational diffusion to protein association. J Am Chem Soc (2005) 1.39
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Effect of crowding on protein-protein association rates: fundamental differences between low and high mass crowding agents. J Mol Biol (2004) 1.34
Common crowding agents have only a small effect on protein-protein interactions. Biophys J (2009) 1.33
The stability of the ternary interferon-receptor complex rather than the affinity to the individual subunits dictates differential biological activities. J Biol Chem (2008) 1.33
eMovie: a storyboard-based tool for making molecular movies. Trends Biochem Sci (2007) 1.29
Stochastic receptor expression determines cell fate upon interferon treatment. Mol Cell Biol (2011) 1.26
Mutational analysis of the IFNAR1 binding site on IFNalpha2 reveals the architecture of a weak ligand-receptor binding-site. J Mol Biol (2005) 1.25
Binding and activity of all human alpha interferon subtypes. Cytokine (2011) 1.24
Receptor density is key to the alpha2/beta interferon differential activities. Mol Cell Biol (2009) 1.22
The fast release of sticky protons: kinetics of substrate binding and proton release in a multidrug transporter. Proc Natl Acad Sci U S A (2007) 1.20
On the contribution of water-mediated interactions to protein-complex stability. Biochemistry (2007) 1.19
Exploring the charge space of protein-protein association: a proteomic study. Proteins (2005) 1.14
Fruitful and futile encounters along the association reaction between proteins. Biophys J (2009) 1.08
Upregulation of a small subset of genes drives type I interferon-induced antiviral memory. J Interferon Cytokine Res (2007) 1.05
On the dynamic nature of the transition state for protein-protein association as determined by double-mutant cycle analysis and simulation. J Mol Biol (2007) 1.01
Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity. J Mol Biol (2006) 1.00
The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding. Structure (2003) 0.98
Protein-binding dynamics imaged in a living cell. Proc Natl Acad Sci U S A (2012) 0.97
Noncovalent, site-specific biotinylation of histidine-tagged proteins. Anal Chem (2007) 0.96
Formation of protein complexes in crowded environments--from in vitro to in vivo. FEBS Lett (2013) 0.94
Contrasting factors on the kinetic path to protein complex formation diminish the effects of crowding agents. Biophys J (2012) 0.93
Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists. Biochemistry (2008) 0.91
Understanding hydrogen-bond patterns in proteins using network motifs. Bioinformatics (2009) 0.91
Docking of antizyme to ornithine decarboxylase and antizyme inhibitor using experimental mutant and double-mutant cycle data. J Mol Biol (2009) 0.90
Similar chemistry, but different bond preferences in inter versus intra-protein interactions. Proteins (2008) 0.90
Reversible PEGylation: a novel technology to release native interferon alpha2 over a prolonged time period. J Med Chem (2004) 0.90
The human interferon receptor: NMR-based modeling, mapping of the IFN-alpha 2 binding site, and observed ligand-induced tightening. Biochemistry (2002) 0.90
Binding Characteristics of IFN-alpha Subvariants to IFNAR2-EC and Influence of the 6-Histidine Tag. J Interferon Cytokine Res (2006) 0.88
Optimizing the binding affinity of a carrier protein: a case study on the interaction between soluble ifnar2 and interferon beta. J Biol Chem (2004) 0.87
A novel method for scoring of docked protein complexes using predicted protein-protein binding sites. Protein Eng Des Sel (2004) 0.87
Cluster conservation as a novel tool for studying protein-protein interactions evolution. Proteins (2008) 0.86
Four distances between pairs of amino acids provide a precise description of their interaction. PLoS Comput Biol (2009) 0.86
Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands. Mol Cell Biol (2012) 0.84
Protein structure modelling and evaluation based on a 4-distance description of side-chain interactions. BMC Bioinformatics (2010) 0.83
Improved binding of raf to Ras.GDP is correlated with biological activity. J Biol Chem (2009) 0.83
PyInteraph: a framework for the analysis of interaction networks in structural ensembles of proteins. J Chem Inf Model (2014) 0.82
A quantitative, real-time assessment of binding of peptides and proteins to gold surfaces. Chemistry (2010) 0.80
Three-dimensional structure determination of proteins related to human health in their functional context at The Israel Structural Proteomics Center (ISPC). This paper was presented at ICCBM10. Acta Crystallogr D Biol Crystallogr (2005) 0.80
Protein-surface interactions: challenging experiments and computations. J Mol Recognit (2010) 0.79
ProMateus--an open research approach to protein-binding sites analysis. Nucleic Acids Res (2007) 0.78
Rediscovering secondary structures as network motifs--an unsupervised learning approach. Bioinformatics (2007) 0.78
FRETex: a FRET-based, high-throughput technique to analyze protein-protein interactions. Protein Eng Des Sel (2012) 0.77
Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency. Nature (2015) 0.77
The nitty-gritty of protein interactions. Structure (2005) 0.76
"4D Biology for health and disease" workshop report. N Biotechnol (2010) 0.75