Published in Gastroenterology on February 01, 1992
Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol (1994) 2.41
KASL Clinical Practice Guidelines: Management of chronic hepatitis B. Clin Mol Hepatol (2012) 2.10
Posttranscriptional regulation of hepatitis B virus replication by the precore protein. J Virol (1997) 1.96
The influence of hepatitis B virus genotype and subgenotype on the natural history of chronic hepatitis B. Hepatol Int (2008) 1.77
Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal. Proc Natl Acad Sci U S A (1994) 1.76
Pathogenesis of hepatitis B virus infection. World J Gastroenterol (2007) 1.47
Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. J Virol (1994) 1.44
Rapid and sensitive assays for determination of hepatitis B virus (HBV) genotypes and detection of HBV precore and core promoter variants. J Clin Microbiol (2003) 1.43
Replication of the wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture. J Virol (2001) 1.09
Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation. J Clin Invest (1994) 1.09
KASL clinical practice guidelines: management of chronic hepatitis B. Clin Mol Hepatol (2016) 1.07
Precore stop mutant in HBeAg-positive patients with chronic hepatitis B: clinical characteristics and correlation with the course of HBeAg-to-anti-HBe seroconversion. J Clin Microbiol (2002) 1.02
Mechanisms of inhibition of nuclear hormone receptor-dependent hepatitis B virus replication by hepatocyte nuclear factor 3beta. J Virol (2002) 1.01
A survey of liver pathology in needle biopsies from HBsAg and anti-HBe positive individuals. J Clin Pathol (2000) 1.00
Prevalence and clinical significance of hepatitis B Basal core promoter and precore gene mutations in southern Iranian patients. Hepat Mon (2010) 0.93
Reactivation of viral replication after liver resection in patients infected with hepatitis B virus. Ann Surg (2001) 0.89
Clinical relevance of mutations in the precore genome of the hepatitis B virus. Gut (1995) 0.88
Complete hepatitis B virus genome analysis in HBsAg positive mothers and their infants with fulminant hepatitis B. BMC Gastroenterol (2004) 0.86
Comparison of complete sequences of hepatitis B virus genotype C between inactive carriers and hepatocellular carcinoma patients before and after seroconversion. J Gastroenterol (2007) 0.82
The two different states of hepatitis B virus DNA in asymptomatic carriers: HBe-antigen-positive versus anti-HBe-positive asymptomatic carriers. Dig Dis Sci (1998) 0.80
In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. J Virol (2007) 0.78
High risk of hepatitis B virus reactivation in nucleos(t)ide analogue-induced hepatitis B e antigen seroconverters older than 40 years. Dig Dis Sci (2014) 0.77
Liver disease. Postgrad Med J (1994) 0.76
Host immune response and variations in the virus genome: pathogenesis of liver damage caused by hepatitis B virus. Gut (1994) 0.75
Association of the core clustering mutations (codon 21-34) and the severity of chronic hepatitis B in Korean patients. Korean J Intern Med (1995) 0.75
RNA Exosome Complex Regulates Stability of the Hepatitis B Virus X-mRNA Transcript in a Non-stop-mediated (NSD) RNA Quality Control Mechanism. J Biol Chem (2016) 0.75
What is expected from the pathologist in the diagnosis of viral hepatitis? Virchows Arch (2011) 0.75
Database of homology-derived protein structures and the structural meaning of sequence alignment. Proteins (1991) 32.50
Selection of representative protein data sets. Protein Sci (1992) 15.62
The HSSP database of protein structure-sequence alignments and family profiles. Nucleic Acids Res (1998) 9.59
Rb targets histone H3 methylation and HP1 to promoters. Nature (2001) 8.26
A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts. Gene (1984) 7.36
PHD--an automatic mail server for protein secondary structure prediction. Comput Appl Biosci (1994) 6.71
Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C. Gastroenterology (1999) 5.79
Correlated mutations and residue contacts in proteins. Proteins (1994) 5.20
Signals regulating hepatitis B surface antigen transcription. Nature (1983) 5.02
Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet (1995) 4.71
Comparative sequence analysis of duck and human hepatitis B virus genomes. J Med Virol (1985) 4.68
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus. J Virol (2001) 4.48
Replication strategy of human hepatitis B virus. J Virol (1987) 4.42
Transcripts and the putative RNA pregenome of duck hepatitis B virus: implications for reverse transcription. Cell (1985) 4.41
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science (2001) 4.18
T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature (1988) 4.04
Hepatitis B virus transcription in the infected liver. EMBO J (1984) 3.44
Differences in genotypes of Helicobacter pylori from different human populations. J Bacteriol (2000) 3.39
Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction. Lancet (1999) 3.38
CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur J Immunol (2000) 3.36
A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol (1995) 3.35
Isolation and characterization of a hepatitis B virus endemic in herons. J Virol (1988) 3.23
Concerns about game ranching. Can Vet J (1990) 3.07
Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem (1996) 3.00
Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. J Cell Biol (1997) 2.98
Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C. J Infect Dis (2000) 2.98
Cloned HBV DNA causes hepatitis in chimpanzees. Nature (1982) 2.80
Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis. J Immunol (1990) 2.73
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus. Hepatology (2001) 2.71
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem (1998) 2.71
Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur J Biochem (1997) 2.63
Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli. J Biol Chem (2000) 2.58
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature (1994) 2.57
Protein fold recognition by prediction-based threading. J Mol Biol (1997) 2.51
A sensitive and rapid gel retention assay for nuclear factor I and other DNA-binding proteins in crude nuclear extracts. Nucleic Acids Res (1986) 2.45
Regulation of p53 activity in nuclear bodies by a specific PML isoform. EMBO J (2000) 2.38
Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients. Crit Care Med (1999) 2.35
Progress in protein structure prediction? Trends Biochem Sci (1993) 2.34
Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis. J Virol (1998) 2.28
IFN enhance expression of Sp100, an autoantigen in primary biliary cirrhosis. J Immunol (1992) 2.24
The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers. J Biol Chem (1999) 2.21
Infectious hepatitis B virus from cloned DNA of known nucleotide sequence. Proc Natl Acad Sci U S A (1985) 2.20
The use of a token system in project Head Start. J Appl Behav Anal (1970) 2.20
Survey of animal neoplasms in Alameda and Contra Costa Counties, California. II. Cancer morbidity in dogs and cats from Alameda County. J Natl Cancer Inst (1968) 2.08
Bacterial community associated with Pfiesteria-like dinoflagellate cultures. Environ Microbiol (2001) 2.06
Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. Proc Natl Acad Sci U S A (1991) 2.05
[21-year-old patient with recurrent diarrhea, weight loss, leg edema and iron deficiency. Gluten sensitive sprue]. Internist (Berl) (2002) 2.04
MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation. Nat Genet (2001) 2.04
Putative reverse transcriptase intermediates of human hepatitis B virus in primary liver carcinomas. Science (1986) 2.00
First pass annotation of promoters on human chromosome 22. Genome Res (2001) 1.99
Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection. J Virol (1997) 1.98
A supernova origin for dust in a high-redshift quasar. Nature (2004) 1.97
Monoclonal antibodies against chromosomal proteins of Drosophila melanogaster: establishment of antibody producing cell lines and partial characterization of corresponding antigens. Chromosoma (1980) 1.97
Expression of the hepatitis B virus core gene in vitro and in vivo. J Virol (1987) 1.96
The HSSP database of protein structure-sequence alignments. Nucleic Acids Res (1994) 1.96
The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity. J Virol (1992) 1.95
Clinical features and outcome of pediatric Wegener's granulomatosis. Arthritis Rheum (2007) 1.91
Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein. J Mol Biol (1999) 1.90
Homeopathic proving symptoms: result of a local, non-local, or placebo process? A blinded, placebo-controlled pilot study. Homeopathy (2004) 1.88
Deletion of self-reactive T cells before entry into the thymus medulla. Nature (1988) 1.88
Positive selection of CD4+ thymocytes controlled by MHC class II gene products. Nature (1988) 1.86
Gluten subfractions in coeliac disease. Lancet (1972) 1.86
Redefining the goals of protein secondary structure prediction. J Mol Biol (1994) 1.84
Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. J Virol (1984) 1.80
Expression of hepatitis B antigens with a simian virus 40 vector. J Virol (1984) 1.80
Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications. Proc Natl Acad Sci U S A (1985) 1.79
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. Hepatology (2001) 1.78
Osteoid osteomas of the femoral neck: report of four cases evaluated with isotopic bone scanning, CT, and MR imaging. Radiology (1993) 1.76
Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier. Virology (1993) 1.75
Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. Proc Natl Acad Sci U S A (1988) 1.75
Exploring the Mycoplasma capricolum genome: a minimal cell reveals its physiology. Mol Microbiol (1995) 1.74
Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides. Mol Cell (2001) 1.74
Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection. Hepatology (1995) 1.72
Naturally occurring variants of hepatitis B virus. Adv Virus Res (1999) 1.72
Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection. J Virol (1995) 1.71
Sarcoidosis associated with interferon-alpha therapy for chronic hepatitis C. J Hepatol (1998) 1.67
Loss of the nerve monitoring signal during bilateral thyroid surgery. Br J Surg (2012) 1.67
Molecular biology of viral and nonviral retroelements. Trends Genet (1989) 1.65
Serological pattern "anti-HBc alone": report on a workshop. J Med Virol (2000) 1.65
Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III. Protein Sci (1992) 1.64
A test for the assessment of the duration of the action of neostigmine and of the relative potencies of various anticholinesterases using the pupil of the mouse. J Pharm Pharmacol (1970) 1.64
Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J Biol Chem (1996) 1.64
Challenging times for bioinformatics. Nature (1995) 1.63
Body language: the function of PML nuclear bodies in apoptosis regulation. Cell Death Differ (2003) 1.62
The HSSP data base of protein structure-sequence alignments. Nucleic Acids Res (1993) 1.61
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc Natl Acad Sci U S A (1997) 1.60
Detection of an element of the SV40 late promoter in vectors used for expression studies in COS cells. EMBO J (1983) 1.57
DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma. Oncogene (2000) 1.56