Published in J Biol Chem on February 27, 2007
Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells. Cell Host Microbe (2009) 1.39
Targeting of several glycolytic enzymes using RNA interference reveals aldolase affects cancer cell proliferation through a non-glycolytic mechanism. J Biol Chem (2012) 1.02
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration. PLoS One (2014) 0.95
Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain. Proteomics Clin Appl (2009) 0.88
Mechanism of aldolase control of sorting nexin 9 function in endocytosis. J Biol Chem (2010) 0.88
Proteomic profiling of the mesenteric lymph after hemorrhagic shock: Differential gel electrophoresis and mass spectrometry analysis. Clin Proteomics (2010) 0.87
Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant. Acta Crystallogr D Biol Crystallogr (2008) 0.81
Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase. Acta Crystallogr F Struct Biol Commun (2014) 0.76
Identification of aldolase A as a potential diagnostic biomarker for colorectal cancer based on proteomic analysis using formalin-fixed paraffin-embedded tissue. Tumour Biol (2016) 0.75
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. Nature (2008) 5.38
Structural dynamics of alpha-actinin-vinculin interactions. Mol Cell Biol (2005) 2.12
Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J Exp Med (2011) 2.03
Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo. Nat Struct Mol Biol (2006) 1.94
Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure (2009) 1.77
Crystal structure of human vinculin. Structure (2004) 1.73
The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin. J Biol Chem (2006) 1.62
Identification of the binding site of Brucella VirB8 interaction inhibitors. Chem Biol (2012) 1.58
Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells. Cell Host Microbe (2009) 1.39
Crystal structures of DNA-Whirly complexes and their role in Arabidopsis organelle genome repair. Plant Cell (2010) 1.28
High resolution reaction intermediates of rabbit muscle fructose-1,6-bisphosphate aldolase: substrate cleavage and induced fit. J Biol Chem (2005) 1.28
A new family of plant transcription factors displays a novel ssDNA-binding surface. Nat Struct Biol (2002) 1.20
Vinculin binding in its closed conformation by a helix addition mechanism. EMBO J (2007) 1.18
Induced fit movements and metal cofactor selectivity of class II aldolases: structure of Thermus aquaticus fructose-1,6-bisphosphate aldolase. J Biol Chem (2003) 1.10
The cytoskeletal protein α-catenin unfurls upon binding to vinculin. J Biol Chem (2012) 1.08
Dimer asymmetry defines α-catenin interactions. Nat Struct Mol Biol (2013) 1.07
The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J Biol Chem (2011) 1.03
Substrate-induced asymmetry and channel closure revealed by the apoenzyme structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase. Protein Sci (2004) 1.02
Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli. J Biol Chem (2011) 1.00
Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain. FEBS Lett (2007) 0.98
A helix replacement mechanism directs metavinculin functions. PLoS One (2010) 0.97
Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics. Chemistry (2008) 0.94
Novel vinculin binding site of the IpaA invasin of Shigella. J Biol Chem (2011) 0.93
Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation. J Biol Chem (2008) 0.92
Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase. J Biol Chem (2007) 0.92
Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei. J Med Chem (2006) 0.89
Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase. Biochemistry (2009) 0.88
Mechanism of aldolase control of sorting nexin 9 function in endocytosis. J Biol Chem (2010) 0.88
Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem (2010) 0.87
Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor. Protein Sci (2011) 0.87
Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases. Bioorg Med Chem Lett (2008) 0.86
A conserved lysine residue of plant Whirly proteins is necessary for higher order protein assembly and protection against DNA damage. Nucleic Acids Res (2011) 0.86
Crystallization and preliminary X-ray crystallographic analysis of p24, a component of the potato nuclear factor PBF-2. Acta Crystallogr D Biol Crystallogr (2002) 0.86
Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0). J Biol Chem (2010) 0.85
Improving the diffraction of full-length human selenomethionyl metavinculin crystals by streak-seeding. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.85
Carboxy-terminus recruitment induced by substrate binding in eukaryotic fructose bis-phosphate aldolases. Biochemistry (2007) 0.84
Purification, crystallization and preliminary X-ray diffraction analysis of the Whirly domain of StWhy2 in complex with single-stranded DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.83
Structure of a class I tagatose-1,6-bisphosphate aldolase: investigation into an apparent loss of stereospecificity. J Biol Chem (2010) 0.82
Crystal structure of the N-terminal domains of the surface cell antigen 4 of Rickettsia. Protein Sci (2013) 0.80
Rhombohedral crystals of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase. Acta Crystallogr D Biol Crystallogr (2003) 0.80
Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin. Protein Sci (2012) 0.80
A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases. J Biol Chem (2002) 0.79
Apo raver1 structure reveals distinct RRM domain orientations. Protein Sci (2011) 0.78
A family portrait: structural comparison of the Whirly proteins from Arabidopsis thaliana and Solanum tuberosum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase. Biochemistry (2005) 0.77
The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA. J Mol Biol (2012) 0.77
Purification, crystallization and preliminary X-ray analysis of native and selenomethionine class I tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes. Acta Crystallogr D Biol Crystallogr (2004) 0.77
Crystallization of HLA-DR4 fused to an immunodominant collagen II peptide implicated in rheumatoid arthritis. Acta Crystallogr D Biol Crystallogr (2002) 0.77
Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity. J Biol Chem (2012) 0.75
Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry (2016) 0.75
Rhombohedral crystals of the human vinculin head domain in complex with a vinculin-binding site of talin. Acta Crystallogr D Biol Crystallogr (2004) 0.75