Published in J Biol Chem on February 02, 2010
Molecular regulation of NKCC2 in the thick ascending limb. Am J Physiol Renal Physiol (2011) 1.28
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Dynamin2, clathrin, and lipid rafts mediate endocytosis of the apical Na/K/2Cl cotransporter NKCC2 in thick ascending limbs. J Biol Chem (2012) 0.95
Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. Am J Physiol Cell Physiol (2011) 0.91
Aldolase positively regulates of the canonical Wnt signaling pathway. Mol Cancer (2014) 0.85
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Structural and functional divergence of the aldolase fold in Toxoplasma gondii. J Mol Biol (2014) 0.76
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Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Evolutionary Changes on the Way to Clathrin-Mediated Endocytosis in Animals. Genome Biol Evol (2016) 0.75
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Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol (2002) 2.93
Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane. Proc Natl Acad Sci U S A (2005) 2.44
The subunit structure of mammalian fructose diphosphate aldolase. Biochemistry (1967) 2.24
SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis. Mol Biol Cell (2005) 2.08
Sites of interaction between aldolase and thrombospondin-related anonymous protein in plasmodium. Mol Biol Cell (2003) 1.83
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Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. Proc Natl Acad Sci U S A (2007) 1.31
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Site-directed mutagenesis identifies aspartate 33 as a previously unidentified critical residue in the catalytic mechanism of rabbit aldolase A. J Biol Chem (1993) 1.22
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Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. J Biol Chem (1999) 1.13
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The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton. J Biol Chem (2001) 1.08
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Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein. J Biol Chem (2005) 0.98
Phospholipase D2 directly interacts with aldolase via Its PH domain. Biochemistry (2002) 0.97
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Fructose 1,6-bisphosphate: isomeric composition, kinetics, and substrate specificity for the aldolases. Biochemistry (1976) 0.96
A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein. J Biol Chem (2007) 0.96
Overexpression of caveolin-1 results in increased plasma membrane targeting of glycolytic enzymes: the structural basis for a membrane associated metabolic compartment. J Cell Biochem (2006) 0.94
Spectrophotometric measurement of hexokinase and phosphohexokinase activity. J Biol Chem (1947) 0.91
Aldolase-localization in cultured cells: cell-type and substrate-specific regulation of cytoskeletal associations. Biochem Cell Biol (2001) 0.84
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. Nature (2008) 5.38
Structural dynamics of alpha-actinin-vinculin interactions. Mol Cell Biol (2005) 2.12
Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J Exp Med (2011) 2.03
Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo. Nat Struct Mol Biol (2006) 1.94
Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure (2009) 1.77
Crystal structure of human vinculin. Structure (2004) 1.73
The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin. J Biol Chem (2006) 1.62
Identification of the binding site of Brucella VirB8 interaction inhibitors. Chem Biol (2012) 1.58
Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells. Cell Host Microbe (2009) 1.39
Crystal structures of DNA-Whirly complexes and their role in Arabidopsis organelle genome repair. Plant Cell (2010) 1.28
High resolution reaction intermediates of rabbit muscle fructose-1,6-bisphosphate aldolase: substrate cleavage and induced fit. J Biol Chem (2005) 1.28
A new family of plant transcription factors displays a novel ssDNA-binding surface. Nat Struct Biol (2002) 1.20
Vinculin binding in its closed conformation by a helix addition mechanism. EMBO J (2007) 1.18
Crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution. Mol Microbiol (2004) 1.14
Induced fit movements and metal cofactor selectivity of class II aldolases: structure of Thermus aquaticus fructose-1,6-bisphosphate aldolase. J Biol Chem (2003) 1.10
The cytoskeletal protein α-catenin unfurls upon binding to vinculin. J Biol Chem (2012) 1.08
Dimer asymmetry defines α-catenin interactions. Nat Struct Mol Biol (2013) 1.07
Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J Biol Chem (2003) 1.05
The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J Biol Chem (2011) 1.03
Substrate-induced asymmetry and channel closure revealed by the apoenzyme structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase. Protein Sci (2004) 1.02
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules. Nat Commun (2013) 1.01
Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli. J Biol Chem (2011) 1.00
Myotonic dystrophy type 1 RNA crystal structures reveal heterogeneous 1 × 1 nucleotide UU internal loop conformations. Biochemistry (2011) 1.00
Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain. FEBS Lett (2007) 0.98
A helix replacement mechanism directs metavinculin functions. PLoS One (2010) 0.97
A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein. J Biol Chem (2007) 0.96
Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics. Chemistry (2008) 0.94
Novel vinculin binding site of the IpaA invasin of Shigella. J Biol Chem (2011) 0.93
Interaction between cardiac calsequestrin and drugs with known cardiotoxicity. Mol Pharmacol (2004) 0.92
Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation. J Biol Chem (2008) 0.92
Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase. J Biol Chem (2007) 0.92
TonB interacts with nonreceptor proteins in the outer membrane of Escherichia coli. J Bacteriol (2002) 0.91
Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei. J Med Chem (2006) 0.89
Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase. Biochemistry (2009) 0.88
Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem (2010) 0.87
A toxic RNA catalyzes the in cellulo synthesis of its own inhibitor. Angew Chem Int Ed Engl (2014) 0.87
Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor. Protein Sci (2011) 0.87
Crystallization and preliminary X-ray crystallographic analysis of p24, a component of the potato nuclear factor PBF-2. Acta Crystallogr D Biol Crystallogr (2002) 0.86
A conserved lysine residue of plant Whirly proteins is necessary for higher order protein assembly and protection against DNA damage. Nucleic Acids Res (2011) 0.86
Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases. Bioorg Med Chem Lett (2008) 0.86
Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0). J Biol Chem (2010) 0.85
Improving the diffraction of full-length human selenomethionyl metavinculin crystals by streak-seeding. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.85
A dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations. J Am Chem Soc (2013) 0.84
Carboxy-terminus recruitment induced by substrate binding in eukaryotic fructose bis-phosphate aldolases. Biochemistry (2007) 0.84
Purification, crystallization and preliminary X-ray diffraction analysis of the Whirly domain of StWhy2 in complex with single-stranded DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.83
Synthesis of benzoquinone ansamycin-inspired macrocyclic lactams from shikimic acid. Angew Chem Int Ed Engl (2013) 0.83
Structure of a class I tagatose-1,6-bisphosphate aldolase: investigation into an apparent loss of stereospecificity. J Biol Chem (2010) 0.82
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. ACS Chem Biol (2013) 0.81
Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin. Protein Sci (2012) 0.80
Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10). Biochemistry (2015) 0.80
Rhombohedral crystals of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase. Acta Crystallogr D Biol Crystallogr (2003) 0.80
Crystal structure of the N-terminal domains of the surface cell antigen 4 of Rickettsia. Protein Sci (2013) 0.80
A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases. J Biol Chem (2002) 0.79
Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives. J Med Chem (2014) 0.79
A family portrait: structural comparison of the Whirly proteins from Arabidopsis thaliana and Solanum tuberosum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
Apo raver1 structure reveals distinct RRM domain orientations. Protein Sci (2011) 0.78
Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors. J Med Chem (2015) 0.78
Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase. Biochemistry (2005) 0.77
Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors. J Med Chem (2013) 0.77
Purification, crystallization and preliminary X-ray analysis of native and selenomethionine class I tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes. Acta Crystallogr D Biol Crystallogr (2004) 0.77
The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA. J Mol Biol (2012) 0.77
Crystallization of HLA-DR4 fused to an immunodominant collagen II peptide implicated in rheumatoid arthritis. Acta Crystallogr D Biol Crystallogr (2002) 0.77
Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity. J Biol Chem (2012) 0.75
Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry (2016) 0.75
Rhombohedral crystals of the human vinculin head domain in complex with a vinculin-binding site of talin. Acta Crystallogr D Biol Crystallogr (2004) 0.75
Corrigendum: A Toxic RNA Catalyzes the In Cellulo Synthesis of Its Own Inhibitor. Angew Chem Int Ed Engl (2016) 0.75
Correction to Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives. J Med Chem (2016) 0.75