Published in Drug Metab Pharmacokinet on February 25, 2007
Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity. Toxins (Basel) (2010) 0.88
Effect of impaired renal function on the pharmacokinetics of tomopenem (RO4908463/CS-023), a novel carbapenem. Antimicrob Agents Chemother (2008) 0.78
In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. Antimicrob Agents Chemother (2008) 0.75
Renal Drug Transporters and Drug Interactions. Clin Pharmacokinet (2017) 0.75
Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Ann Intern Med (2007) 6.98
A promoter-level mammalian expression atlas. Nature (2014) 6.25
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature (2004) 3.77
Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. Drug Metab Dispos (2010) 3.06
Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cells (2004) 2.38
The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity. Cancer Cell (2006) 2.09
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential. Development (2006) 1.88
Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J (2005) 1.77
A novel subunit structure of Clostridium botulinum serotype D toxin complex with three extended arms. J Biol Chem (2007) 1.59
Plasma platelet-derived microparticles in patients with connective tissue diseases. J Rheumatol (2011) 1.44
Activity of capuramycin analogues against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium intracellulare in vitro and in vivo. J Antimicrob Chemother (2004) 1.41
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci U S A (2004) 1.27
Cancer incidence in systemic sclerosis: meta-analysis of population-based cohort studies. Arthritis Rheum (2013) 1.23
Thyroid hormone transporters: recent advances. Trends Endocrinol Metab (2002) 1.20
In vitro and in vivo antibacterial activities of CS-023 (RO4908463), a novel parenteral carbapenem. Antimicrob Agents Chemother (2005) 1.19
OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker. Drug Metab Dispos (2006) 1.19
Polycyclic N-heterocyclic compounds. Part 63: Improved synthesis of 5-amino-1,2-dihydrofuro[2,3-c]isoquinolines via truce-smiles rearrangement and subsequent formation to furo[2,3-c]isoquinoline. Chem Pharm Bull (Tokyo) (2010) 1.19
Diagnostic accuracy of serum 1,3-β-D-glucan for pneumocystis jiroveci pneumonia, invasive candidiasis, and invasive aspergillosis: systematic review and meta-analysis. J Clin Microbiol (2011) 1.18
Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method. J Pharm Sci (2004) 1.13
Prevalence of disease-specific antinuclear antibodies in general population: estimates from annual physical examinations of residents of a small town over a 5-year period. Mod Rheumatol (2008) 1.13
T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage. Blood (2006) 1.11
Utility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension. J Am Soc Echocardiogr (2011) 1.10
Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier. J Pharmacol Exp Ther (2003) 1.08
Role of nontoxic components of serotype D botulinum toxin complex in permeation through a Caco-2 cell monolayer, a model for intestinal epithelium. FEMS Immunol Med Microbiol (2007) 1.06
A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel. Drug Metab Dispos (2009) 1.05
HA-33 facilitates transport of the serotype D botulinum toxin across a rat intestinal epithelial cell monolayer. FEMS Immunol Med Microbiol (2011) 0.99
Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma. Blood (2012) 0.99
Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers. Antimicrob Agents Chemother (2006) 0.98
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. J Pharmacol Exp Ther (2002) 0.98
Humanization of excretory pathway in chimeric mice with humanized liver. Toxicol Sci (2007) 0.98
Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells. Int J Dev Biol (2005) 0.97
Variation in hematopoietic potential of induced pluripotent stem cell lines. Stem Cell Rev (2010) 0.96
A multiple dose study of prasugrel (CS-747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans. Br J Clin Pharmacol (2006) 0.96
Preoperative systolic strain rate predicts postoperative left ventricular dysfunction in patients with chronic aortic regurgitation. Circ Cardiovasc Imaging (2010) 0.95
Hemogenic endothelium: a vessel for blood production. Int J Biochem Cell Biol (2012) 0.95
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport. Pharm Res (2002) 0.94
Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a single ascending dose study in healthy humans. Platelets (2006) 0.93
Molecular characterization of human and rat organic anion transporter OATP-D. Am J Physiol Renal Physiol (2003) 0.92
Involvement of reactive oxygen species in sonodynamically induced apoptosis using a novel porphyrin derivative. Theranostics (2012) 0.91
Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse. Development (2010) 0.91
Diagnostic accuracy of serum procalcitonin concentrations for detecting systemic bacterial infection in patients with systemic autoimmune diseases. J Rheumatol (2007) 0.91
Serum matrix metalloproteinase-3 as predictor of joint destruction in rheumatoid arthritis, treated with non-biological disease modifying anti-rheumatic drugs. Kobe J Med Sci (2010) 0.89
Mechanism-based inhibition of human cytochrome P450 2B6 by ticlopidine, clopidogrel, and the thiolactone metabolite of prasugrel. Drug Metab Dispos (2008) 0.89
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor. Drug Metab Dispos (2007) 0.89
Importance of skin perfusion pressure in treatment of critical limb ischemia. Wounds (2008) 0.89
Plasma tetrahydrobiopterin/dihydrobiopterin ratio: a possible marker of endothelial dysfunction. Circ J (2009) 0.88
Inhibitory effects of angiotensin receptor blockers on CYP2C9 activity in human liver microsomes. Drug Metab Pharmacokinet (2007) 0.88
Long-term deleterious effects of aortohepatic conduits in primary liver transplantation: proceed with caution. Liver Transpl (2013) 0.88
Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine. Drug Metab Pharmacokinet (2008) 0.87
Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine. J Biol Chem (2010) 0.87
Does high-sensitivity C-reactive protein or low-density lipoprotein cholesterol show a stronger relationship with the cardio-ankle vascular index in healthy community dwellers?: the KOBE study. J Atheroscler Thromb (2012) 0.87
Pharmacokinetics and disposition of CS-023 (RO4908463), a novel parenteral carbapenem, in animals. Antimicrob Agents Chemother (2006) 0.86
Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response. Eur Heart J (2012) 0.86
SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production. Biochem Biophys Res Commun (2011) 0.85
Tissue distribution of humanized anti-human Fas monoclonal antibody (R-125224) based on fas antigen-antibody reaction in collagen-induced arthritis monkeys. Life Sci (2007) 0.85
Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis. PLoS One (2012) 0.85
Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells. Stem Cell Res Ther (2013) 0.85
The quantitative prediction of CYP-mediated drug interaction by physiologically based pharmacokinetic modeling. Pharm Res (2008) 0.85
Obesity was associated with a decreased postoperative recurrence of rectal cancer in a Japanese population. Surg Today (2014) 0.85
Incidence and aggravation of cervical spine instabilities in rheumatoid arthritis: a prospective minimum 5-year follow-up study of patients initially without cervical involvement. Spine (Phila Pa 1976) (2012) 0.85
Sialic acid-dependent binding and transcytosis of serotype D botulinum neurotoxin and toxin complex in rat intestinal epithelial cells. Vet Microbiol (2009) 0.84
Production of biogenic manganese oxides by repeated-batch cultures of laboratory microcosms. J Biosci Bioeng (2007) 0.84
Thioredoxin may exert a protective effect against tissue damage caused by oxidative stress in salivary glands of patients with Sjögren's syndrome. J Rheumatol (2007) 0.84
Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: a multiple-dose study in healthy humans. Platelets (2006) 0.84
Importance of vital signs to the early diagnosis and severity of sepsis: association between vital signs and sequential organ failure assessment score in patients with sepsis. Intern Med (2012) 0.83
Cryoablation provides superior local control of primary hepatocellular carcinomas of >2 cm compared with radiofrequency ablation and microwave coagulation therapy: an underestimated tool in the toolbox. Ann Surg Oncol (2014) 0.83
Molecular pathways governing development of vascular endothelial cells from ES/iPS cells. Stem Cell Rev (2013) 0.83
Phenol sulfotransferase, ST1A3, as the main enzyme catalyzing sulfation of troglitazone in human liver. Drug Metab Dispos (2002) 0.83
Cold exposure down-regulates zebrafish hematopoiesis. Biochem Biophys Res Commun (2010) 0.82
Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population. Psychiatry Res (2011) 0.82
Glutaredoxin and thioredoxin can be involved in producing the pharmacologically active metabolite of a thienopyridine antiplatelet agent, prasugrel. Drug Metab Dispos (2010) 0.82
Herbal drug ninjin'yoeito accelerates myelopoiesis but not erythropoiesis in vitro. Genes Cells (2014) 0.82
What is the most adapted indication of prophylactic pancreatic duct stent within the high-risk group of post-endoscopic retrograde cholangiopancreatography pancreatitis? Using the propensity score analysis. J Hepatobiliary Pancreat Sci (2013) 0.81
Effects of postnatal dexamethasone treatment on mRNA expression profiles of genes related to alveolar development in an emphysema model in mice. J Toxicol Sci (2014) 0.81
Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites. Drug Metab Dispos (2005) 0.81
Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells. Drug Metab Dispos (2009) 0.81
Involvement of sialic acid in transport of serotype C1 botulinum toxins through rat intestinal epithelial cells. J Vet Med Sci (2010) 0.81
Respiratory chain inhibition by fullerene derivatives: hydrogen peroxide production caused by fullerene derivatives and a respiratory chain system. Bioorg Med Chem (2003) 0.81
Human UDP-glucuronosyltransferase, UGT1A8, glucuronidates dihydrotestosterone to a monoglucuronide and further to a structurally novel diglucuronide. Drug Metab Dispos (2006) 0.81
Mesodermal and hematopoietic differentiation from ES and iPS cells. Stem Cell Rev (2013) 0.80
Hemocompatibility of a hydrodynamic levitation centrifugal blood pump. J Artif Organs (2007) 0.80
Metabolic stability and uptake by human hepatocytes of pitavastatin, a new inhibitor of HMG-CoA reductase. Arzneimittelforschung (2004) 0.80
Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6). Anticancer Res (2011) 0.80
Enhancement of the inhibitory activity of oatp antisense oligonucleotides by incorporation of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) without a loss of subtype selectivity. Biochemistry (2004) 0.80
Widespread lipoplex-mediated gene transfer to vascular endothelial cells and hemangioblasts in the vertebrate embryo. Dev Dyn (2006) 0.80
Continuous Regional Arterial Infusion of Protease Inhibitors Has No Efficacy in the Treatment of Severe Acute Pancreatitis: A Retrospective Multicenter Cohort Study. Pancreas (2016) 0.80
Zebrafish erythropoiesis and the utility of fish as models of anemia. Stem Cell Res Ther (2012) 0.80
Paraoxonase 1 as a major bioactivating hydrolase for olmesartan medoxomil in human blood circulation: molecular identification and contribution to plasma metabolism. Drug Metab Dispos (2011) 0.80
Clostridium botulinum serotype D neurotoxin and toxin complex bind to bovine aortic endothelial cells via sialic acid. FEMS Immunol Med Microbiol (2008) 0.80
Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population. Mod Rheumatol (2009) 0.79
Novel organic nitrate prodrug 4(R)-N-(2-Nitroxyethyl)-2-oxothiazolidine-4-carboxamide (RS-7897) serves as a xenobiotic substrate for pyroglutamyl aminopeptidase I in dogs. Drug Metab Pharmacokinet (2003) 0.79
Glutaredoxin is involved in the formation of the pharmacologically active metabolite of clopidogrel from its GSH conjugate. Drug Metab Dispos (2012) 0.79
Is SS-A/Ro52 a hydrogen peroxide-sensitive signaling molecule? Antioxid Redox Signal (2007) 0.79
Sonodynamically induced cell damage and membrane lipid peroxidation by novel porphyrin derivative, DCPH-P-Na(I). Anticancer Res (2010) 0.79