Michael A McGuckin

Author PubWeight™ 56.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med 2008 4.24
2 Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol 2008 3.63
3 Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. Am J Gastroenterol 2010 3.32
4 MUC1 cell surface mucin is a critical element of the mucosal barrier to infection. J Clin Invest 2007 2.90
5 Mucin dynamics in intestinal bacterial infection. PLoS One 2008 1.88
6 Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. JAMA 2013 1.88
7 IgG antibodies against common gut bacteria are more diagnostic for Crohn's disease than IgG against mannan or flagellin. Am J Gastroenterol 2007 1.71
8 MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy. PLoS Pathog 2009 1.69
9 Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res 2010 1.32
10 The interplay between endoplasmic reticulum stress and inflammation. Immunol Cell Biol 2012 1.31
11 Campylobacter jejuni response to human mucin MUC2: modulation of colonization and pathogenicity determinants. J Med Microbiol 2008 1.19
12 A novel microbiota stratification system predicts future exacerbations in bronchiectasis. Ann Am Thorac Soc 2014 1.17
13 Spontaneous apoptosis of blood dendritic cells in patients with breast cancer. Breast Cancer Res 2005 1.14
14 The MUC13 cell surface mucin is highly expressed by human colorectal carcinomas. Hum Pathol 2007 1.14
15 Mucins in inflammatory bowel diseases and colorectal cancer. J Gastroenterol Hepatol 2012 1.14
16 The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis. Gut 2011 1.13
17 Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins. Protein Sci 2002 1.10
18 β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. Arthritis Rheum 2012 1.10
19 Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype. Mod Pathol 2013 1.04
20 A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system. Cell Microbiol 2012 1.04
21 Expression of the cell surface mucin gene family in adenocarcinomas. Int J Oncol 2004 1.04
22 IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells. Gastroenterology 2012 1.02
23 Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier. PLoS Negl Trop Dis 2012 0.99
24 Localized suppression of inflammation at sites of Helicobacter pylori colonization. Infect Immun 2011 0.98
25 Improved in vitro model systems for gastrointestinal infection by choice of cell line, pH, microaerobic conditions, and optimization of culture conditions. Helicobacter 2007 0.96
26 ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice. Arthritis Rheumatol 2014 0.96
27 Listeria monocytogenes internalins bind to the human intestinal mucin MUC2. Arch Microbiol 2008 0.96
28 KCNN4 gene variant is associated with ileal Crohn's Disease in the Australian and New Zealand population. Am J Gastroenterol 2010 0.95
29 Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis Rheumatol 2014 0.92
30 Expression of MUC1 splice variants in benign and malignant ovarian tumours. Int J Cancer 2002 0.92
31 Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. J Exp Med 2013 0.88
32 Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment. PLoS One 2013 0.88
33 Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells. BMC Cell Biol 2009 0.86
34 Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis. Ann Am Thorac Soc 2015 0.86
35 Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice. Gut 2012 0.86
36 Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulation. PLoS One 2013 0.85
37 O-Linked glycome and proteome of high-molecular-mass proteins in human ovarian cancer ascites: Identification of sulfation, disialic acid and O-linked fucose. Glycobiology 2012 0.84
38 Muc1 limits Helicobacter felis binding to gastric epithelial cells but does not limit colonization and gastric pathology following infection. Helicobacter 2008 0.84
39 Techniques for assessment of interactions of mucins with microbes and parasites in vitro and in vivo. Methods Mol Biol 2012 0.83
40 T cell transfer model of colitis: a great tool to assess the contribution of T cells in chronic intestinal inflammation. Methods Mol Biol 2012 0.83
41 Endocrine impact of Helicobacter pylori: focus on ghrelin and ghrelin o-acyltransferase. World J Gastroenterol 2011 0.82
42 A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut 2012 0.79
43 Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model. Inflamm Bowel Dis 2015 0.79
44 Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after immunomagnetic separation. J Basic Microbiol 2012 0.79
45 Detecting, visualising, and quantifying mucins. Methods Mol Biol 2012 0.77
46 Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. Mod Pathol 2013 0.75