Published in Hum Pathol on March 13, 2007
Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer (2009) 5.31
Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells. Oncogene (2010) 2.10
Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. Gastroenterology (2010) 1.64
MUC13 mucin augments pancreatic tumorigenesis. Mol Cancer Ther (2011) 1.19
Current status of mucins in the diagnosis and therapy of cancer. Biofactors (2009) 1.17
Gene expression in Barrett's esophagus: laser capture versus whole tissue. Scand J Gastroenterol (2009) 1.09
Mucin 13: structure, function, and potential roles in cancer pathogenesis. Mol Cancer Res (2011) 1.04
Genome-wide expression patterns associated with oncogenesis and sarcomatous transdifferentation of cholangiocarcinoma. BMC Cancer (2011) 1.00
Mucins as diagnostic and prognostic biomarkers in a fish-parasite model: transcriptional and functional analysis. PLoS One (2013) 0.87
Increased expression and aberrant localization of mucin 13 in metastatic colon cancer. J Histochem Cytochem (2012) 0.87
Overexpression of mucin 13 due to promoter methylation promotes aggressive behavior in ovarian cancer cells. Yonsei Med J (2014) 0.84
Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer. Cancer Biol Ther (2014) 0.79
Mucin-Microbiota Interaction During Postnatal Maturation of the Intestinal Ecosystem: Clinical Implications. Dig Dis Sci (2016) 0.78
MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target. Oncogene (2016) 0.77
Functions and regulation of MUC13 mucin in colon cancer cells. J Gastroenterol (2013) 0.77
Lectins from the Red Marine Algal Species Bryothamnion seaforthii and Bryothamnion triquetrum as Tools to Differentiate Human Colon Carcinoma Cells. Adv Pharmacol Sci (2009) 0.77
Mucins and toll-like receptors: kith and kin in infection and cancer. Cancer Lett (2012) 0.76
High expression of Mucin13 associates with grimmer postoperative prognosis of patients with non-metastatic clear-cell renal cell carcinoma. Oncotarget (2016) 0.75
Colonic transcriptional response to 1α,25(OH)2 vitamin D3 in African- and European-Americans. J Steroid Biochem Mol Biol (2017) 0.75
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol (2002) 5.91
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med (2008) 4.24
Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med (2008) 3.76
Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol (2008) 3.63
Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. Am J Gastroenterol (2010) 3.32
Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept. Am J Clin Pathol (2005) 3.29
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology (2006) 3.24
Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer. J Clin Oncol (2005) 3.19
Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome. J Natl Cancer Inst (2013) 3.06
MUC1 cell surface mucin is a critical element of the mucosal barrier to infection. J Clin Invest (2007) 2.90
Investigating iron deficiency anaemia. Med J Aust (2013) 2.60
Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome. J Natl Cancer Inst (2012) 2.44
Emerging concepts in colorectal neoplasia. Gastroenterology (2002) 2.44
Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study. Gastroenterology (2007) 2.39
Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery. Gut (2010) 2.30
Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation. J Clin Oncol (2004) 2.27
Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol (2012) 2.22
Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer. J Clin Pathol (2006) 2.17
Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family study. Clin Gastroenterol Hepatol (2006) 2.12
Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc (2008) 2.09
Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer. Clin Gastroenterol Hepatol (2005) 2.03
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling. PLoS One (2009) 1.90
Mucin dynamics in intestinal bacterial infection. PLoS One (2008) 1.88
Cancer risks for relatives of patients with serrated polyposis. Am J Gastroenterol (2012) 1.88
IgG antibodies against common gut bacteria are more diagnostic for Crohn's disease than IgG against mannan or flagellin. Am J Gastroenterol (2007) 1.71
MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy. PLoS Pathog (2009) 1.69
Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer. Cancer Res (2002) 1.67
Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: classification, molecular genetics, natural history, and clinical management. Gastroenterol Clin North Am (2008) 1.65
Cancer risks for MLH1 and MSH2 mutation carriers. Hum Mutat (2013) 1.55
Review of genetic and epigenetic alterations in hepatocarcinogenesis. J Gastroenterol Hepatol (2006) 1.52
Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features. Mod Pathol (2013) 1.47
Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification. J Med Genet (2012) 1.45
The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature. Cancer Epidemiol Biomarkers Prev (2006) 1.41
Oncogenic PIK3CA mutations in colorectal cancers and polyps. Int J Cancer (2011) 1.40
Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype. Cancer Epidemiol Biomarkers Prev (2008) 1.36
Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics. PLoS One (2010) 1.36
Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics. Hum Mutat (2009) 1.35
Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis. Int J Epidemiol (2012) 1.33
Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res (2010) 1.32
The interplay between endoplasmic reticulum stress and inflammation. Immunol Cell Biol (2012) 1.31
Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study. Int J Colorectal Dis (2010) 1.27
A new prognostic staging system for rectal cancer. Ann Surg (2004) 1.26
Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes Chromosomes Cancer (2004) 1.26
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer. JAMA (2005) 1.24
Node-negative colorectal cancer at high risk of distant metastasis identified by combined analysis of lymph node status, vascular invasion, and Raf-1 kinase inhibitor protein expression. Clin Cancer Res (2008) 1.23
Loss of raf-1 kinase inhibitor protein expression is associated with tumor progression and metastasis in colorectal cancer. Am J Clin Pathol (2007) 1.22
Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases. Clin Cancer Res (2003) 1.22
Emerging pathways in colorectal-cancer development. Lancet Oncol (2002) 1.20
Campylobacter jejuni response to human mucin MUC2: modulation of colonization and pathogenicity determinants. J Med Microbiol (2008) 1.19
Colorectal cancer: molecular features and clinical opportunities. Clin Biochem Rev (2010) 1.19
Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management. J Gastroenterol (2012) 1.18
The impact of microsatellite instability on the molecular phenotype of colorectal tumors. Cancer Res (2003) 1.18
A novel microbiota stratification system predicts future exacerbations in bronchiectasis. Ann Am Thorac Soc (2014) 1.17
PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer. Clin Cancer Res (2013) 1.17
BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome. Am J Surg Pathol (2013) 1.16
Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development. Genes Chromosomes Cancer (2008) 1.15
Intergroup communication between hospital doctors: implications for quality of patient care. Soc Sci Med (2009) 1.15
Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients. Clin Cancer Res (2008) 1.15
Spontaneous apoptosis of blood dendritic cells in patients with breast cancer. Breast Cancer Res (2005) 1.14
Mucins in inflammatory bowel diseases and colorectal cancer. J Gastroenterol Hepatol (2012) 1.14
PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival. PLoS One (2013) 1.13
The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis. Gut (2011) 1.13
Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer. Mod Pathol (2007) 1.13
Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer. Cancer (2008) 1.12
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer. Int J Cancer (2011) 1.10
Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins. Protein Sci (2002) 1.10
Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: a potential role for dysregulation of the transforming growth factor-beta pathway. Eur J Cancer (2007) 1.10
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. Arthritis Rheum (2012) 1.10
Mutation deep within an intron of MSH2 causes Lynch syndrome. Fam Cancer (2011) 1.09
Colorectal cancer prevention in inflammatory bowel disease and the role of 5-aminosalicylic acid: a clinical review and update. Inflamm Bowel Dis (2008) 1.09
Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation. Clin Cancer Res (2005) 1.07
Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients. Carcinogenesis (2011) 1.07
Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning. Cancer Res (2004) 1.05
Family history of colorectal cancer in BRAF p.V600E-mutated colorectal cancer cases. Cancer Epidemiol Biomarkers Prev (2013) 1.05
Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype. Mod Pathol (2013) 1.04
A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system. Cell Microbiol (2012) 1.04