| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
2
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
|
3
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
4
|
Multiple loci identified in a genome-wide association study of prostate cancer.
|
Nat Genet
|
2008
|
17.65
|
|
5
|
Identification of ten loci associated with height highlights new biological pathways in human growth.
|
Nat Genet
|
2008
|
16.25
|
|
6
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
|
7
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
8
|
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
|
Nat Genet
|
2013
|
5.58
|
|
9
|
Complications after prostate biopsy: data from SEER-Medicare.
|
J Urol
|
2011
|
5.40
|
|
10
|
Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium.
|
Lancet Oncol
|
2006
|
4.13
|
|
11
|
Is repeat prostate biopsy associated with a greater risk of hospitalization? Data from SEER-Medicare.
|
J Urol
|
2012
|
4.11
|
|
12
|
Detectable clonal mosaicism and its relationship to aging and cancer.
|
Nat Genet
|
2012
|
3.69
|
|
13
|
Detectable clonal mosaicism from birth to old age and its relationship to cancer.
|
Nat Genet
|
2012
|
3.68
|
|
14
|
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.
|
Nat Genet
|
2011
|
3.07
|
|
15
|
The landscape of recombination in African Americans.
|
Nature
|
2011
|
3.06
|
|
16
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
17
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
|
18
|
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21.
|
Nat Genet
|
2011
|
2.70
|
|
19
|
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
|
Gastroenterology
|
2012
|
2.57
|
|
20
|
Genome-wide association study identifies new prostate cancer susceptibility loci.
|
Hum Mol Genet
|
2011
|
2.51
|
|
21
|
Variation in KLK genes, prostate-specific antigen and risk of prostate cancer.
|
Nat Genet
|
2008
|
2.45
|
|
22
|
Meta-analysis of new genome-wide association studies of colorectal cancer risk.
|
Hum Genet
|
2011
|
2.35
|
|
23
|
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
Nat Genet
|
2012
|
2.26
|
|
24
|
Genome-wide association study identifies two susceptibility loci for osteosarcoma.
|
Nat Genet
|
2013
|
2.21
|
|
25
|
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
|
Carcinogenesis
|
2009
|
2.17
|
|
26
|
Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
|
Blood
|
2006
|
2.06
|
|
27
|
Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies.
|
Int J Cancer
|
2009
|
2.01
|
|
28
|
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
|
Nat Genet
|
2013
|
1.82
|
|
29
|
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.
|
Hum Mol Genet
|
2013
|
1.78
|
|
30
|
Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
|
PLoS Genet
|
2011
|
1.77
|
|
31
|
Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour.
|
J Med Genet
|
2011
|
1.73
|
|
32
|
Hematopoietic malignancies associated with viral and alcoholic hepatitis.
|
Cancer Epidemiol Biomarkers Prev
|
2008
|
1.59
|
|
33
|
Characterization of gene-environment interactions for colorectal cancer susceptibility loci.
|
Cancer Res
|
2012
|
1.58
|
|
34
|
Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study.
|
Cancer Epidemiol Biomarkers Prev
|
2007
|
1.58
|
|
35
|
Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans.
|
PLoS Genet
|
2011
|
1.54
|
|
36
|
Genetic polymorphisms of interleukin-1B (IL-1B), IL-6, IL-8, and IL-10 and risk of prostate cancer.
|
Cancer Res
|
2006
|
1.52
|
|
37
|
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
|
PLoS Genet
|
2011
|
1.47
|
|
38
|
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
|
Hum Mol Genet
|
2012
|
1.47
|
|
39
|
Variation in lung cancer risk by smoky coal subtype in Xuanwei, China.
|
Int J Cancer
|
2008
|
1.45
|
|
40
|
Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
|
PLoS One
|
2011
|
1.41
|
|
41
|
Improved imputation of common and uncommon SNPs with a new reference set.
|
Nat Genet
|
2011
|
1.34
|
|
42
|
Polymorphisms in the DNA nucleotide excision repair genes and lung cancer risk in Xuan Wei, China.
|
Int J Cancer
|
2005
|
1.32
|
|
43
|
Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma.
|
Carcinogenesis
|
2006
|
1.32
|
|
44
|
Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
1.29
|
|
45
|
Meta-analysis of gene-level associations for rare variants based on single-variant statistics.
|
Am J Hum Genet
|
2013
|
1.24
|
|
46
|
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
|
Hum Mol Genet
|
2013
|
1.23
|
|
47
|
Selected genetic polymorphisms in MGMT, XRCC1, XPD, and XRCC3 and risk of head and neck cancer: a pooled analysis.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
1.19
|
|
48
|
Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk.
|
Cancer Res
|
2009
|
1.18
|
|
49
|
Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer.
|
Hum Mol Genet
|
2011
|
1.17
|
|
50
|
Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2010
|
1.17
|
|
51
|
Genome-wide association study of relative telomere length.
|
PLoS One
|
2011
|
1.16
|
|
52
|
PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3).
|
Carcinogenesis
|
2009
|
1.13
|
|
53
|
Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.
|
Carcinogenesis
|
2008
|
1.10
|
|
54
|
Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.
|
Cancer Epidemiol Biomarkers Prev
|
2006
|
1.07
|
|
55
|
Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer.
|
Cancer Res
|
2010
|
1.06
|
|
56
|
Polymorphisms in folate metabolic genes and lung cancer risk in Xuan Wei, China.
|
Lung Cancer
|
2005
|
1.05
|
|
57
|
Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.
|
Am J Epidemiol
|
2012
|
1.05
|
|
58
|
Polymorphisms in the DNA base excision repair genes APEX1 and XRCC1 and lung cancer risk in Xuan Wei, China.
|
Anticancer Res
|
2005
|
1.04
|
|
59
|
A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
|
J Clin Endocrinol Metab
|
2010
|
1.04
|
|
60
|
Polymorphisms in immunoregulatory genes, smoky coal exposure and lung cancer risk in Xuan Wei, China.
|
Carcinogenesis
|
2007
|
1.02
|
|
61
|
Telomere length and variation in telomere biology genes in individuals with osteosarcoma.
|
Int J Mol Epidemiol Genet
|
2010
|
1.01
|
|
62
|
Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3).
|
Hum Mol Genet
|
2009
|
1.01
|
|
63
|
A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.
|
Hum Genet
|
2009
|
1.01
|
|
64
|
Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer.
|
Cancer Res
|
2010
|
1.00
|
|
65
|
GST genotypes and lung cancer susceptibility in Asian populations with indoor air pollution exposures: a meta-analysis.
|
Mutat Res
|
2007
|
1.00
|
|
66
|
A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma.
|
BMC Cancer
|
2011
|
1.00
|
|
67
|
Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.
|
Cancer Epidemiol Biomarkers Prev
|
2010
|
0.99
|
|
68
|
Variants in blood pressure genes and the risk of renal cell carcinoma.
|
Carcinogenesis
|
2010
|
0.99
|
|
69
|
HNF1B and JAZF1 genes, diabetes, and prostate cancer risk.
|
Prostate
|
2010
|
0.98
|
|
70
|
Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.
|
Cancer Res
|
2009
|
0.97
|
|
71
|
CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the Breast and Prostate Cancer Cohort Consortium.
|
Cancer Epidemiol Biomarkers Prev
|
2009
|
0.97
|
|
72
|
Polymorphisms in estrogen-metabolizing and estrogen receptor genes and the risk of developing breast cancer among a cohort of women with benign breast disease.
|
BMC Cancer
|
2006
|
0.96
|
|
73
|
Generalizability of established prostate cancer risk variants in men of African ancestry.
|
Int J Cancer
|
2014
|
0.96
|
|
74
|
Prospective evaluation of serum sarcosine and risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.
|
Carcinogenesis
|
2013
|
0.96
|
|
75
|
Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations.
|
Immunogenetics
|
2007
|
0.96
|
|
76
|
Prospective investigation of body mass index, colorectal adenoma, and colorectal cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.
|
J Clin Oncol
|
2013
|
0.95
|
|
77
|
Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases.
|
Hum Genet
|
2015
|
0.95
|
|
78
|
Characterization of 9p24 risk locus and colorectal adenoma and cancer: gene-environment interaction and meta-analysis.
|
Cancer Epidemiol Biomarkers Prev
|
2010
|
0.95
|
|
79
|
Replication of five prostate cancer loci identified in an Asian population--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
|
Cancer Epidemiol Biomarkers Prev
|
2011
|
0.95
|
|
80
|
Genetic variation in cell cycle and apoptosis related genes and multiple myeloma risk.
|
Leuk Res
|
2009
|
0.94
|
|
81
|
An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.
|
PLoS One
|
2009
|
0.93
|
|
82
|
Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women.
|
Pharmacogenet Genomics
|
2006
|
0.93
|
|
83
|
Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancer.
|
Alcohol Clin Exp Res
|
2007
|
0.93
|
|
84
|
Genetic variation at chromosome 8q24 in osteosarcoma cases and controls.
|
Carcinogenesis
|
2010
|
0.92
|
|
85
|
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia.
|
Gut
|
2013
|
0.92
|
|
86
|
Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans.
|
Hum Mol Genet
|
2013
|
0.92
|
|
87
|
Prospective study of genomic hypomethylation of leukocyte DNA and colorectal cancer risk.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.91
|
|
88
|
Nitric oxide synthase gene polymorphisms and prostate cancer risk.
|
Carcinogenesis
|
2009
|
0.91
|
|
89
|
Common genetic variants and central adiposity among Asian-Indians.
|
Obesity (Silver Spring)
|
2011
|
0.91
|
|
90
|
Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.
|
Hum Genet
|
2011
|
0.90
|
|
91
|
Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.
|
Pharmacogenet Genomics
|
2011
|
0.89
|
|
92
|
Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma.
|
Environ Mol Mutagen
|
2012
|
0.89
|
|
93
|
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
0.89
|
|
94
|
Comprehensive assessment of genetic variation of catechol-O-methyltransferase and breast cancer risk.
|
Cancer Res
|
2006
|
0.89
|
|
95
|
Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma.
|
Int J Cancer
|
2011
|
0.88
|
|
96
|
Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk.
|
Carcinogenesis
|
2011
|
0.88
|
|
97
|
Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer.
|
Carcinogenesis
|
2012
|
0.88
|
|
98
|
Comprehensive resequence analysis of a 97 kb region of chromosome 10q11.2 containing the MSMB gene associated with prostate cancer.
|
Hum Genet
|
2009
|
0.88
|
|
99
|
Occupational sunlight exposure and risk of renal cell carcinoma.
|
Cancer
|
2010
|
0.87
|
|
100
|
Smoky coal exposure, NBS1 polymorphisms, p53 protein accumulation, and lung cancer risk in Xuan Wei, China.
|
Lung Cancer
|
2005
|
0.87
|
|
101
|
Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead.
|
PLoS One
|
2011
|
0.87
|
|
102
|
DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas.
|
Carcinogenesis
|
2011
|
0.87
|
|
103
|
Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk.
|
Environ Health Perspect
|
2011
|
0.86
|
|
104
|
A report of cytokine polymorphisms and COPD risk in Xuan Wei, China.
|
Int J Hyg Environ Health
|
2007
|
0.86
|
|
105
|
Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.
|
Int J Cancer
|
2013
|
0.84
|
|
106
|
Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
|
Int J Cancer
|
2013
|
0.84
|
|
107
|
Genetic contributions to the association between adult height and testicular germ cell tumors.
|
Int J Epidemiol
|
2011
|
0.84
|
|
108
|
Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2013
|
0.84
|
|
109
|
Genetic variants of adiponectin and risk of colorectal cancer.
|
Int J Cancer
|
2014
|
0.84
|
|
110
|
Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.84
|
|
111
|
Genetic variants reflecting higher vitamin e status in men are associated with reduced risk of prostate cancer.
|
J Nutr
|
2014
|
0.83
|
|
112
|
Lack of association of transforming growth factor-beta1 polymorphisms and haplotypes with prostate cancer risk in the prostate, lung, colorectal, and ovarian trial.
|
Cancer Epidemiol Biomarkers Prev
|
2007
|
0.83
|
|
113
|
Interactions between genome-wide significant genetic variants and circulating concentrations of insulin-like growth factor 1, sex hormones, and binding proteins in relation to prostate cancer risk in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
|
Am J Epidemiol
|
2012
|
0.82
|
|
114
|
Genetic susceptibility loci, pesticide exposure and prostate cancer risk.
|
PLoS One
|
2013
|
0.82
|
|
115
|
Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New England.
|
Int J Cancer
|
2012
|
0.80
|
|
116
|
Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma.
|
Prostate
|
2010
|
0.80
|
|
117
|
Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry.
|
Hum Genet
|
2012
|
0.79
|
|
118
|
Polymorphisms in complement system genes and risk of non-Hodgkin lymphoma.
|
Environ Mol Mutagen
|
2011
|
0.79
|
|
119
|
Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
|
World Rev Nutr Diet
|
2010
|
0.78
|
|
120
|
The Interaction between Pesticide Use and Genetic Variants Involved in Lipid Metabolism on Prostate Cancer Risk.
|
J Cancer Epidemiol
|
2012
|
0.78
|
|
121
|
Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer.
|
Prostate
|
2012
|
0.77
|
|
122
|
Corrigendum: Genome-wide association study of colorectal cancer identifies six new susceptibility loci.
|
Nat Commun
|
2015
|
0.76
|
|
123
|
Innate immunity gene polymorphisms and the risk of colorectal neoplasia.
|
Carcinogenesis
|
2013
|
0.75
|
|
124
|
Xenobiotic metabolizing genes, meat-related exposures, and risk of advanced colorectal adenoma.
|
J Nutrigenet Nutrigenomics
|
2011
|
0.75
|
|
125
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
126
|
Interactions Between Genome-Wide Significant Genetic Variants and Circulating Concentrations of 25-Hydroxyvitamin D in Relation to Prostate Cancer Risk in the National Cancer Institute BPC3.
|
Am J Epidemiol
|
2017
|
0.75
|
|
127
|
Aspirin use and mortality in two contemporary U.S. cohorts.
|
Epidemiology
|
2017
|
0.75
|
|
128
|
Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).
|
Hum Genet
|
2015
|
0.75
|