Thermodynamic benchmark study using Biacore technology.

Fragment screening by surface plasmon resonance. ACS Med Chem Lett (2010) 0.93

Biosensor-based fragment screening using FastStep injections. Anal Biochem (2010) 0.92

A global benchmark study using affinity-based biosensors. Anal Biochem (2008) 0.91

Biophysical characterization of recombinant proteins: a key to higher structural genomics success. J Struct Biol (2010) 0.88

Titration calorimetry standards and the precision of isothermal titration calorimetry data. Int J Mol Sci (2009) 0.88

Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators. Bioorg Med Chem Lett (2014) 0.78

Real-time Recognition of Mycobacterium tuberculosis and Lipoarabinomannan using the Quartz Crystal Microbalance. Sens Actuators B Chem (2012) 0.77

Applications of SPR for the characterization of molecules important in the pathogenesis and treatment of neurodegenerative diseases. Expert Rev Neurother (2014) 0.76

Optimizing Multiple Analyte Injections in Surface Plasmon Resonance Biosensors with Analytes having Different Refractive Index Increments. Sci Rep (2015) 0.75

Thermo-kinetic analysis space expansion for cyclophilin-ligand interactions - identification of a new nonpeptide inhibitor using Biacore™ T200. FEBS Open Bio (2017) 0.75

Enthalpy screen of drug candidates. Anal Biochem (2016) 0.75

Rapid screening of IgG quality attributes - effects on Fc receptor binding. FEBS Open Bio (2017) 0.75

The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36

Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'. J Mol Recognit (2009) 3.25

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc Natl Acad Sci U S A (2007) 3.24

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein. Proc Natl Acad Sci U S A (2004) 3.16

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell (2007) 3.12

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell (2009) 2.84

E2 interaction and dimerization in the crystal structure of TRAF6. Nat Struct Mol Biol (2009) 2.79

Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. J Biol Chem (2004) 2.66

Structure and functional interactions of the Tsg101 UEV domain. EMBO J (2002) 2.40

R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol Biol Cell (2008) 2.37

Analyzing a kinetic titration series using affinity biosensors. Anal Biochem (2005) 2.27

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1. Mol Cell (2005) 2.26

Src phosphorylation of cortactin enhances actin assembly. Proc Natl Acad Sci U S A (2007) 2.16

Direct comparison of binding equilibrium, thermodynamic, and rate constants determined by surface- and solution-based biophysical methods. Protein Sci (2002) 2.13

Structural basis for ESCRT-III protein autoinhibition. Nat Struct Mol Biol (2009) 1.98

Vitamin D intakes by children and adults in the United States differ among ethnic groups. J Nutr (2005) 1.88

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature (2012) 1.85

Kinetic analysis of beta-amyloid fibril elongation. Anal Biochem (2004) 1.78

Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV. Nat Struct Mol Biol (2007) 1.76

Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120. J Virol (2008) 1.71

Exploring "one-shot" kinetics and small molecule analysis using the ProteOn XPR36 array biosensor. Anal Biochem (2006) 1.62

Vitamin D intake in the United States. J Am Diet Assoc (2004) 1.58

Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac. J Biol Chem (2003) 1.54

Higher-throughput, label-free, real-time molecular interaction analysis. Anal Biochem (2006) 1.47

Chromatographic isolation of methionine-containing peptides for gel-free proteome analysis: identification of more than 800 Escherichia coli proteins. Mol Cell Proteomics (2002) 1.42

Solubilization, stabilization, and purification of chemokine receptors using biosensor technology. Anal Biochem (2005) 1.36

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra. NMR Biomed (2006) 1.35

The Pseudomonas siderophore quinolobactin is synthesized from xanthurenic acid, an intermediate of the kynurenine pathway. Mol Microbiol (2004) 1.33

Survey of the year 2007 commercial optical biosensor literature. J Mol Recognit (2008) 1.32

Kinetic analysis of a high-affinity antibody/antigen interaction performed by multiple Biacore users. Anal Biochem (2006) 1.31

Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. J Exp Med (2002) 1.27

Molecular basis for passive immunotherapy of Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.26

Kinetic analysis of estrogen receptor/ligand interactions. Proc Natl Acad Sci U S A (2002) 1.26

Comparative proteome analysis of Chlamydia trachomatis serovar A, D and L2. Proteomics (2002) 1.25

Xenopus U8 snoRNA binding protein is a conserved nuclear decapping enzyme. Mol Cell (2004) 1.24

RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J Med Chem (2009) 1.24

White matter fiber tracking in patients with space-occupying lesions of the brain: a new technique for neurosurgical planning? Neuroimage (2003) 1.21

Extracting kinetic rate constants from surface plasmon resonance array systems. Anal Biochem (2007) 1.21

Characterizing high-affinity antigen/antibody complexes by kinetic- and equilibrium-based methods. Anal Biochem (2004) 1.18

Structural models for interactions between the 20S proteasome and its PAN/19S activators. J Biol Chem (2009) 1.17

Survey of the 2009 commercial optical biosensor literature. J Mol Recognit (2011) 1.15

Screening antibody-antigen interactions in parallel using Biacore A100. Anal Biochem (2006) 1.14

Catalysis and sulfa drug resistance in dihydropteroate synthase. Science (2012) 1.14

Analyzing ligand and small molecule binding activity of solubilized GPCRs using biosensor technology. Anal Biochem (2006) 1.13

The diaphanous inhibitory domain/diaphanous autoregulatory domain interaction is able to mediate heterodimerization between mDia1 and mDia2. J Biol Chem (2007) 1.13

Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers. Clin Cancer Res (2014) 1.13

Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology. Anal Biochem (2006) 1.11

Survey of the year 2003 commercial optical biosensor literature. J Mol Recognit (2004) 1.09

Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a non-covalent ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway. J Mol Biol (2007) 1.08

Two independent histidines, one in human prolactin and one in its receptor, are critical for pH-dependent receptor recognition and activation. J Biol Chem (2010) 1.07

Characterizing a drug's primary binding site on albumin. J Pharm Sci (2003) 1.06

Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell (2012) 1.05

Fragment screening of stabilized G-protein-coupled receptors using biophysical methods. Methods Enzymol (2011) 1.04

Survey of the year 2005 commercial optical biosensor literature. J Mol Recognit (2006) 1.04

Differentiation of metastases from high-grade gliomas using short echo time 1H spectroscopy. J Magn Reson Imaging (2004) 1.04

Survey of the year 2006 commercial optical biosensor literature. J Mol Recognit (2007) 1.03

Kinetic screening of antibodies from crude hybridoma samples using Biacore. Anal Biochem (2004) 1.03

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1. Biochemistry (2008) 1.03

Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases. Nucleic Acids Res (2012) 1.02

Continuous-flow microfluidic printing of proteins for array-based applications including surface plasmon resonance imaging. Anal Biochem (2007) 1.02

Capture and reconstitution of G protein-coupled receptors on a biosensor surface. Anal Biochem (2003) 1.02

Biacore surface matrix effects on the binding kinetics and affinity of an antigen/antibody complex. Anal Biochem (2012) 1.02

Complex role of the beta 2-beta 3 loop in the interaction of U1A with U1 hairpin II RNA. J Biol Chem (2002) 1.01

Survey of the year 2001 commercial optical biosensor literature. J Mol Recognit (2002) 1.00

HIV-1 integrase preassembled on donor DNA is refractory to activity stimulation by LEDGF/p75. Biochemistry (2007) 0.99

Biophysical fragment screening of the β1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design. J Med Chem (2013) 0.99

Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. J Biol Chem (2012) 0.99

Comparative analyses of a small molecule/enzyme interaction by multiple users of Biacore technology. Anal Biochem (2004) 0.98

Generation of a family-specific phage library of llama single chain antibody fragments that neutralize HIV-1. J Biol Chem (2010) 0.98

A biosensor-based approach toward purification and crystallization of G protein-coupled receptors. Anal Biochem (2006) 0.98

Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site. Biochemistry (2002) 0.98

Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior. Biochemistry (2009) 0.98

The kinetics of binding human prolactin, but not growth hormone, to the prolactin receptor vary over a physiologic pH range. Biochemistry (2007) 0.97

Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding. Biochemistry (2002) 0.96

High-resolution characterization of antibody fragment/antigen interactions using Biacore T100. Anal Biochem (2006) 0.96

Probing the mechanism of drug/lipid membrane interactions using Biacore. Anal Biochem (2004) 0.93

High-affinity interaction between IKKbeta and NEMO. Biochemistry (2008) 0.93

Biosensor-based fragment screening using FastStep injections. Anal Biochem (2010) 0.92

Crystal structure of the PH-BEACH domains of human LRBA/BGL. Biochemistry (2004) 0.92

A global benchmark study using affinity-based biosensors. Anal Biochem (2008) 0.91

Biacore analysis with stabilized G-protein-coupled receptors. Anal Biochem (2010) 0.91

Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use. Antimicrob Agents Chemother (2010) 0.90

The first propeller domain of LRP6 regulates sensitivity to DKK1. Mol Biol Cell (2009) 0.90