Published in Mol Cell on October 09, 2009
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Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover. Cell Death Dis (2015) 0.83
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Speckle-type POZ protein, SPOP, is involved in the DNA damage response. Carcinogenesis (2014) 0.82
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Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles. EMBO J (2016) 0.79
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Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling. Front Plant Sci (2015) 0.78
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Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. J Biol Chem (2013) 0.78
Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins. Sci Rep (2015) 0.78
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Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer. Cell Death Dis (2016) 0.75
Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer. Prostate (2014) 0.75
Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants. Arch Biochem Biophys (2016) 0.75
Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection. Nat Commun (2016) 0.75
Stability of HIB-Cul3 E3 ligase adaptor HIB Is Regulated by Self-degradation and Availability of Its Substrates. Sci Rep (2015) 0.75
Speckle-type POZ (pox virus and zinc finger protein) protein gene deletion in ovarian cancer: Fluorescence in situ hybridization analysis of a tissue microarray. Oncol Lett (2016) 0.75
RNA interference-mediated silencing of speckle-type POZ protein promotes apoptosis of renal cell cancer cells. Onco Targets Ther (2016) 0.75
Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer. J Steroid Biochem Mol Biol (2016) 0.75
SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing. Nucleic Acids Res (2016) 0.75
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Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A (2016) 0.75
Identification and Expression Profiling of the BTB Domain-Containing Protein Gene Family in the Silkworm, Bombyx mori. Int J Genomics (2014) 0.75
Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Lett (2016) 0.75
Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells. Mol Cell Biol (2016) 0.75
The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells. Sci Rep (2017) 0.75
SPOP Mutations or ERG Rearrangements Result in Enhanced Levels of ERG to Promote Cell Invasion in Prostate Cancer. Mol Cell (2015) 0.75
GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK. Dev Cell (2017) 0.75
Expression and clinical relevance of SPOPL in medulloblastoma. Oncol Lett (2017) 0.75
Crystal Structure Of The UBR-Box From UBR6/FBXO11 Reveals A Domain Swapping Mediated By Zinc Binding. Protein Sci (2017) 0.75
SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene (2017) 0.75
Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett (2017) 0.75
BPM-CUL3 E3 ligase modulates thermotolerance by facilitating negative regulatory domain-mediated degradation of DREB2A in Arabidopsis. Proc Natl Acad Sci U S A (2017) 0.75
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