Published in BMJ on January 11, 1992
Bactericidal activity of single dose of clarithromycin plus minocycline, with or without ofloxacin, against Mycobacterium leprae in patients. Antimicrob Agents Chemother (1996) 1.87
Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. Antimicrob Agents Chemother (1996) 1.25
Clinical trial of ofloxacin alone and in combination with dapsone plus clofazimine for treatment of lepromatous leprosy. Antimicrob Agents Chemother (1994) 1.19
Clinical trial of clarithromycin for lepromatous leprosy. Antimicrob Agents Chemother (1994) 1.07
Bactericidal activity of a single-dose combination of ofloxacin plus minocycline, with or without rifampin, against Mycobacterium leprae in mice and in lepromatous patients. Antimicrob Agents Chemother (1998) 1.04
Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice. Antimicrob Agents Chemother (1992) 0.92
Use of minocycline in viral infections. Indian J Med Res (2011) 0.92
Clinical trial of sparfloxacin for lepromatous leprosy. Antimicrob Agents Chemother (1994) 0.92
The diarylquinoline R207910 is bactericidal against Mycobacterium leprae in mice at low dose and administered intermittently. Antimicrob Agents Chemother (2009) 0.84
Powerful bactericidal activity of moxifloxacin in human leprosy. Antimicrob Agents Chemother (2008) 0.82
Clinical trial of fusidic acid for lepromatous leprosy. Antimicrob Agents Chemother (1994) 0.78
Peripheral Neuropathy Due to Leprosy. Curr Treat Options Neurol (2002) 0.76
Combination chemoprophylaxis and immunoprophylaxis in reducing the incidence of leprosy. Risk Manag Healthc Policy (2016) 0.75
Another view of the therapy of leprosy. Antimicrob Agents Chemother (1998) 0.75
Nitazoxanide is active against Mycobacterium leprae. PLoS One (2017) 0.75
Clinical trial of pefloxacin and ofloxacin in the treatment of lepromatous leprosy. Int J Lepr Other Mycobact Dis (1990) 2.06
Activity of minocycline in Mycobacterium leprae-infected mice. J Infect Dis (1987) 1.68
Experimental and clinical studies on rifampicin in treatment of leprosy. Br Med J (1970) 1.43
A brief review of experiences with short-term clinical trials monitored by mouse-foot-pad-inoculation. Lepr Rev (1981) 1.34
Effect of low-level and intermittent minocycline therapy on the growth of Mycobacterium leprae in mice. Antimicrob Agents Chemother (1991) 1.03
Proposed supplements and amendments to 'A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects', the Rechtschaffen & Kales (1968) standard. Psychiatry Clin Neurosci (2001) 36.50
Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science (1998) 19.40
Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays. J Clin Microbiol (1999) 11.94
Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science (1991) 8.85
Ordered metal nanohole arrays made by a two-step replication of honeycomb structures of anodic alumina. Science (1995) 8.78
Pandemic versus epidemic influenza mortality: a pattern of changing age distribution. J Infect Dis (1998) 8.51
Effectiveness and cost-benefit of influenza vaccination of healthy working adults: A randomized controlled trial. JAMA (2000) 8.31
Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med (2000) 6.83
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Nature (1988) 6.35
The economic impact of pandemic influenza in the United States: priorities for intervention. Emerg Infect Dis (1999) 5.39
Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest (1999) 5.30
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science (1993) 5.22
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature (1986) 4.97
Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts. J Infect Dis (1999) 4.67
Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions. Nature (1989) 4.61
Case-control study of risk factors for avian influenza A (H5N1) disease, Hong Kong, 1997. J Infect Dis (1999) 4.59
The impact of influenza epidemics on hospitalizations. J Infect Dis (2000) 4.28
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity (1995) 3.99
Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong. J Infect Dis (2000) 3.63
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem (1999) 3.35
PNAD-CSS: a workbench for constructing a protein name abbreviation dictionary. Bioinformatics (2000) 2.98
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair. Circulation (1999) 2.80
Cytokine patterns of immunologically mediated tissue damage. J Immunol (1992) 2.72
Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis. Nature (1985) 2.40
Radiation hybrid mapping of the zebrafish genome. Proc Natl Acad Sci U S A (1999) 2.27
Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis. J Immunol (1989) 2.27
In situ demonstration of T lymphocyte subsets in granulomatous inflammation: leprosy, rhinoscleroma and sarcoidosis. Clin Exp Immunol (1983) 2.21
A gene expression screen in zebrafish embryogenesis. Genome Res (2001) 2.08
The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium. Development (2000) 2.03
T lymphocyte subsets in the skin lesions of patients with leprosy. J Am Acad Dermatol (1983) 2.01
Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy. J Immunol (1993) 2.00
Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel. Nature (1987) 1.99
Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep (2000) 1.99
Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia. AJNR Am J Neuroradiol (2001) 1.98
Decline in sex ratio at birth after Kobe earthquake. Hum Reprod (1998) 1.98
Diode laser transscleral cyclophotocoagulation as a primary surgical treatment for primary open-angle glaucoma. Arch Ophthalmol (2001) 1.98
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep (2001) 1.97
Biomechanical study of the ligamentous system of the acromioclavicular joint. J Bone Joint Surg Am (1986) 1.82
Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization. J Exp Med (1989) 1.82
Gamma delta T lymphocytes in human tuberculosis. J Infect Dis (1992) 1.78
Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage. J Am Coll Cardiol (2001) 1.75
In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor. J Immunol (1984) 1.74
Antigenically distinct conformations of CXCR4. J Virol (2001) 1.74
Patterns of cytokine production by mycobacterium-reactive human T-cell clones. Infect Immun (1993) 1.72
Right-sided ovulation favours pregnancy more than left-sided ovulation. Hum Reprod (2000) 1.71
The epidemiology of chronic fatigue in San Francisco. Am J Med (1998) 1.69
Treatment of neurotrophic keratopathy with substance-P-derived peptide (FGLM) and insulin-like growth factor I. Lancet (1998) 1.65
IL-12 regulates T helper type 1 cytokine responses in human infectious disease. J Immunol (1994) 1.65
Role of acetylcholine receptor subunits in gating of the channel. Nature (1986) 1.63
Learning from lesions: patterns of tissue inflammation in leprosy. Proc Natl Acad Sci U S A (1988) 1.62
A single EGF-like motif of laminin is responsible for high affinity nidogen binding. EMBO J (1993) 1.62
Influenza. Infect Dis Clin North Am (1998) 1.61
Predominance of Th1 immune response in diffuse proliferative lupus nephritis. Arthritis Rheum (2001) 1.61
In situ characterization of T lymphocyte subsets in the reactional states of leprosy. Clin Exp Immunol (1983) 1.60
Genetically restricted suppressor T-cell clones derived from lepromatous leprosy lesions. Nature (1986) 1.56
Chronic variant of myocarditis associated with hepatitis C virus infection. Circulation (1997) 1.56
Two-photon spectroscopy of locked-11-cis-rhodopsin: evidence for a protonated Schiff base in a neutral protein binding site. Proc Natl Acad Sci U S A (1985) 1.55
Tumor necrosis factor production in patients with leprosy. Infect Immun (1992) 1.55
Suppressor T lymphocytes from lepromatous leprosy skin lesions. J Immunol (1986) 1.55
Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure (1995) 1.54
Prevention of hepatocellular carcinoma in patients with chronic active hepatitis C and cirrhosis. Lancet (2001) 1.52
[A study on a self-rating depression scale (author's transl)]. Seishin Shinkeigaku Zasshi (1973) 1.52
ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts. Circ Res (2001) 1.51
An international collaborative study of the effects of coinfection with human T-lymphotropic virus type II on human immunodeficiency virus type 1 disease progression in injection drug users. J Infect Dis (1996) 1.51
The nature of the primary photochemical events in rhodopsin and isorhodopsin. Biophys J (1988) 1.49
Trabeculectomy with intraoperative 5-fluorouracil vs mitomycin C. Am J Ophthalmol (1997) 1.48
Interleukin-6 family of cytokines mediate angiotensin II-induced cardiac hypertrophy in rodent cardiomyocytes. J Biol Chem (2000) 1.46
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood (2000) 1.46
Primary dapsone-resistant Hansen's disease in California. Experience with over 100 Mycobacterium leprae isolates. Arch Dermatol (1990) 1.42
Dynamic transcranial Doppler assessment of positional vertebrobasilar ischemia. Stroke (1994) 1.42
Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells. Oncogene (2011) 1.41
Altered cytokine release in peripheral blood mononuclear cell cultures from patients with the chronic fatigue syndrome. Cytokine (1991) 1.40
T-cell release of granulysin contributes to host defense in leprosy. Nat Med (2001) 1.40
Association of alcohol intake, cigarette smoking, and occupational status with the risk of idiopathic osteonecrosis of the femoral head. Am J Epidemiol (1993) 1.39
Evidence for clonal selection of gamma/delta T cells in response to a human pathogen. J Exp Med (1991) 1.38
DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFalpha, LPS, and cyclic stretch. Physiol Genomics (2004) 1.37
Seven cases of cerebromedullospinal disconnection: the "locked-in" syndrome. Neurology (1971) 1.36
Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res (1998) 1.36
IL-15, an immunomodulator of T cell responses in intracellular infection. J Immunol (1997) 1.34
Energy storage in the primary photochemical events of rhodopsin and isorhodopsin. Biochemistry (1987) 1.33
Significance of ERK cascade compared with JAK/STAT and PI3-K pathway in gp130-mediated cardiac hypertrophy. Am J Physiol Heart Circ Physiol (2000) 1.33
CD1 expression by dendritic cells in human leprosy lesions: correlation with effective host immunity. J Immunol (1999) 1.32
Preparing for pandemic influenza: the need for enhanced surveillance. Emerg Infect Dis (1999) 1.32
A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction. Genes Dev (2000) 1.32
Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart. Circ Res (1997) 1.32
Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes. Circ Res (1999) 1.31
A case of deep soft tissue leiomyoma: CT and MRI findings. Radiat Med (2001) 1.31
Detection of hepatitis C virus antibody in the absence of viral RNA in patients with autoimmune hepatitis. Ann Intern Med (1992) 1.31
Genetic characterization of parthenogenic Fasciola sp. in Japan on the basis of the sequences of ribosomal and mitochondrial DNA. Parasitology (2005) 1.31
Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats. Circ Res (2000) 1.30
Surveillance and impact of influenza in the United States. Vaccine (1999) 1.29
Allergy to insects in Japan. III. High frequency of IgE antibody responses to insects (moth, butterfly, caddis fly, and chironomid) in patients with bronchial asthma and immunochemical quantitation of the insect-related airborne particles smaller than 10 microns in diameter. J Allergy Clin Immunol (1987) 1.29
Quantitation of the phenolic glycolipid of Mycobacterium leprae and relevance to glycolipid antigenemia in leprosy. J Infect Dis (1986) 1.28
Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity. Drug Metab Dispos (2000) 1.27
Cerebrotendinous xanthomatosis: clinical and biochemical evaluation of eight patients and review of the literature. J Neurol Sci (1991) 1.27
Surveillance for chronic fatigue syndrome--four U.S. cities, September 1989 through August 1993. MMWR CDC Surveill Summ (1997) 1.25
IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection. J Immunol (1999) 1.24