Published in Drug Metab Dispos on July 01, 2000
The effect of grapefruit juice on drug disposition. Expert Opin Drug Metab Toxicol (2011) 1.28
Fruit juice inhibition of uptake transport: a new type of food-drug interaction. Br J Clin Pharmacol (2010) 1.20
The grapefruit: an old wine in a new glass? Metabolic and cardiovascular perspectives. Cardiovasc J Afr (2010) 1.03
Mechanisms underlying food-drug interactions: inhibition of intestinal metabolism and transport. Pharmacol Ther (2012) 1.01
Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin. Br J Clin Pharmacol (2005) 0.89
Identification of the residue in human CYP3A4 that is covalently modified by bergamottin and the reactive intermediate that contributes to the grapefruit juice effect. Drug Metab Dispos (2012) 0.89
Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteers. Br J Clin Pharmacol (2009) 0.85
Medicinal importance of grapefruit juice and its interaction with various drugs. Nutr J (2007) 0.83
Influence of dietary substances on intestinal drug metabolism and transport. Curr Drug Metab (2010) 0.82
Impact of citrus soft drinks relative to grapefruit juice on ciclosporin disposition. Br J Clin Pharmacol (2006) 0.81
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models. Clin Pharmacokinet (2016) 0.79
Stable isotope-labelled intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults. Br J Clin Pharmacol (2016) 0.79
Reactive metabolites in the biotransformation of molecules containing a furan ring. Chem Res Toxicol (2012) 0.78
Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice. Antimicrob Agents Chemother (2012) 0.78
S-ketamine concentrations are greatly increased by grapefruit juice. Eur J Clin Pharmacol (2012) 0.78
Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel. Eur J Clin Pharmacol (2003) 0.78
Stereoselective pharmacokinetics of cisapride in healthy volunteers and the effect of repeated administration of grapefruit juice. Br J Clin Pharmacol (2001) 0.77
Different influences on tacrolimus pharmacokinetics by coadministrations of zhi ke and zhi shi in rats. Evid Based Complement Alternat Med (2011) 0.77
A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect". J Clin Pharmacol (2013) 0.76
Interactions of grapefruit juice and cardiovascular medications: A potential risk of toxicity. Exp Clin Cardiol (2003) 0.76
Effect of Low-Furanocoumarin Hybrid Grapefruit Juice Consumption on Midazolam Pharmacokinetics. J Clin Pharmacol (2016) 0.75
Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol (2013) 0.75
Effect of grapefruit juice on the disposition of omeprazole. Br J Clin Pharmacol (2001) 0.75
Co-administration of fresh grape fruit juice (GFJ) and bergamottin prevented paracetamol induced hepatotoxicity after paracetamol overdose in rats. Toxicol Rep (2015) 0.75
Proposed supplements and amendments to 'A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects', the Rechtschaffen & Kales (1968) standard. Psychiatry Clin Neurosci (2001) 36.50
The Average Number of Generations until Fixation of a Mutant Gene in a Finite Population. Genetics (1969) 21.57
Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science (1998) 19.40
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Slightly deleterious mutant substitutions in evolution. Nature (1973) 13.79
A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genet Res (1973) 13.08
Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays. J Clin Microbiol (1999) 11.94
GENIA corpus--semantically annotated corpus for bio-textmining. Bioinformatics (2003) 8.89
Ordered metal nanohole arrays made by a two-step replication of honeycomb structures of anodic alumina. Science (1995) 8.78
Pandemic versus epidemic influenza mortality: a pattern of changing age distribution. J Infect Dis (1998) 8.51
Effectiveness and cost-benefit of influenza vaccination of healthy working adults: A randomized controlled trial. JAMA (2000) 8.31
Linkage disequilibrium at steady state determined by random genetic drift and recurrent mutation. Genetics (1969) 7.33
Role of very slightly deleterious mutations in molecular evolution and polymorphism. Theor Popul Biol (1976) 6.91
Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med (2000) 6.83
Protein polymorphism as a phase of molecular evolution. Nature (1971) 6.68
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Nature (1988) 6.35
The economic impact of pandemic influenza in the United States: priorities for intervention. Emerg Infect Dis (1999) 5.39
Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest (1999) 5.30
On some principles governing molecular evolution. Proc Natl Acad Sci U S A (1974) 4.97
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature (1986) 4.97
Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts. J Infect Dis (1999) 4.67
Case-control study of risk factors for avian influenza A (H5N1) disease, Hong Kong, 1997. J Infect Dis (1999) 4.59
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem (2001) 4.51
The age of a neutral mutant persisting in a finite population. Genetics (1973) 4.44
The impact of influenza epidemics on hospitalizations. J Infect Dis (2000) 4.28
Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80
Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles. Proc Natl Acad Sci U S A (1975) 3.64
Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong. J Infect Dis (2000) 3.63
On the evolution of multigene families. Theor Popul Biol (1983) 3.61
Population biology of antigen presentation by MHC class I molecules. Science (1996) 3.58
Linkage disequilibrium between two segregating nucleotide sites under the steady flux of mutations in a finite population. Genetics (1971) 3.51
Stepwise mutation model and distribution of allelic frequencies in a finite population. Proc Natl Acad Sci U S A (1978) 3.29
PNAD-CSS: a workbench for constructing a protein name abbreviation dictionary. Bioinformatics (2000) 2.98
Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms. Mol Cell Biol (2000) 2.90
Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein. J Biol Chem (1986) 2.84
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair. Circulation (1999) 2.80
Mutation and evolution at the molecular level. Genetics (1973) 2.79
Allelic and nonallelic homology of a supergene family. Proc Natl Acad Sci U S A (1982) 2.72
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66
Purification and characterization of the human interleukin-18 receptor. J Biol Chem (1997) 2.58
Simulating evolution by gene duplication. Genetics (1987) 2.52
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J Cancer Res Clin Oncol (1992) 2.40
Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis. Nature (1985) 2.40
Polyallelic mutational equilibria. Genetics (1975) 2.13
Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin. J Med Chem (1999) 2.10
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Mol Cell Biol (2000) 2.09
The balance between different peptidoglycan precursors determines whether Escherichia coli cells will elongate or divide. J Bacteriol (1990) 2.07
Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker. Biochem Biophys Res Commun (1994) 2.05
Population genetics of multigene families that are dispersed into two or more chromosomes. Proc Natl Acad Sci U S A (1983) 2.05
The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium. Development (2000) 2.03
Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep (2000) 1.99
Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel. Nature (1987) 1.99
Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia. AJNR Am J Neuroradiol (2001) 1.98
Decline in sex ratio at birth after Kobe earthquake. Hum Reprod (1998) 1.98
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc Natl Acad Sci U S A (1999) 1.98
Nucleotide sequence of the pbpA gene and characteristics of the deduced amino acid sequence of penicillin-binding protein 2 of Escherichia coli K12. Eur J Biochem (1986) 1.98
Simple model for treating evolution of multigene families. Nature (1976) 1.98
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep (2001) 1.97
The effect of selected linked locus on heterozygosity of neutral alleles (the hitch-hiking effect). Genet Res (1975) 1.95
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Hum Mol Genet (2003) 1.92
Eukaryotes-prokaryotes divergence estimated by 5S ribosomal RNA sequences. Nat New Biol (1973) 1.88
Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. Am J Hum Genet (2003) 1.82
Biomechanical study of the ligamentous system of the acromioclavicular joint. J Bone Joint Surg Am (1986) 1.82
Cell proliferative activity in intraductal papillary-mucinous neoplasms and invasive ductal adenocarcinomas of the pancreas: an immunohistochemical study. Arch Pathol Lab Med (1998) 1.81
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. Proc Natl Acad Sci U S A (1990) 1.79
Still's disease associated with necrotizing lymphadenitis (Kikuchi's disease): report of 3 cases. J Rheumatol (1988) 1.78
Systemic toxicity and resuscitation in bupivacaine-, levobupivacaine-, or ropivacaine-infused rats. Anesth Analg (2001) 1.76
Complete nucleotide sequence of the chloroplast genome from the green alga Chlorella vulgaris: the existence of genes possibly involved in chloroplast division. Proc Natl Acad Sci U S A (1997) 1.75
Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage. J Am Coll Cardiol (2001) 1.75
Right-sided ovulation favours pregnancy more than left-sided ovulation. Hum Reprod (2000) 1.71
Primary structure of the alpha-subunit of Torpedo californica (Na+ + K+)ATPase deduced from cDNA sequence. Nature (1985) 1.71
The epidemiology of chronic fatigue in San Francisco. Am J Med (1998) 1.69
Behavior of neutral mutants influenced by asociated overdominant loci in finite populations. Genetics (1971) 1.68
A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons. Blood (1998) 1.68
Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. J Clin Invest (2000) 1.67
Treatment of neurotrophic keratopathy with substance-P-derived peptide (FGLM) and insulin-like growth factor I. Lancet (1998) 1.65
Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. Cancer Res (1999) 1.65
Role of acetylcholine receptor subunits in gating of the channel. Nature (1986) 1.63
D-lactate dehydrogenase is a member of the D-isomer-specific 2-hydroxyacid dehydrogenase family. Cloning, sequencing, and expression in Escherichia coli of the D-lactate dehydrogenase gene of Lactobacillus plantarum. J Biol Chem (1991) 1.63
A single EGF-like motif of laminin is responsible for high affinity nidogen binding. EMBO J (1993) 1.62
Development of posterior fossa dural sinuses, emissary veins, and jugular bulb: morphological and radiologic study. AJNR Am J Neuroradiol (1994) 1.61
Influenza. Infect Dis Clin North Am (1998) 1.61
Predominance of Th1 immune response in diffuse proliferative lupus nephritis. Arthritis Rheum (2001) 1.61
Isolation and the gene cloning of an alkaline shock protein in methicillin resistant Staphylococcus aureus. Biochem Biophys Res Commun (1995) 1.60
Results of extensive surgery for pancreatic carcinoma. Cancer (1996) 1.60
Site-directed mutants, at position 166, of RTEM-1 beta-lactamase that form a stable acyl-enzyme intermediate with penicillin. J Biol Chem (1991) 1.59
Development of associative overdominance through linkage disequilibrium in finite populations. Genet Res (1970) 1.59
Nucleotide sequence and characteristics of the gene for L-lactate dehydrogenase of Thermus caldophilus GK24 and the deduced amino-acid sequence of the enzyme. Eur J Biochem (1986) 1.58
Intralesional steroid injection to prevent stricture after endoscopic submucosal dissection for esophageal cancer: a controlled prospective study. Endoscopy (2012) 1.58
Genetic variation in small multigene families. Genet Res (1981) 1.57
Pancreatitis and anomalous union of the pancreaticobiliary ductal system in childhood. J Pediatr Surg (1993) 1.57
Nucleotide sequence of the rodA gene, responsible for the rod shape of Escherichia coli: rodA and the pbpA gene, encoding penicillin-binding protein 2, constitute the rodA operon. J Bacteriol (1989) 1.57
An evaluation of radical resection for pancreatic cancer based on the mode of recurrence as determined by autopsy and diagnostic imaging. Cancer (1993) 1.56
Chronic variant of myocarditis associated with hepatitis C virus infection. Circulation (1997) 1.56
Population size and rate of evolution. J Mol Evol (1972) 1.55
Genes encoding two lipoproteins in the leuS-dacA region of the Escherichia coli chromosome. J Bacteriol (1987) 1.53
Probability of gene fixation in an expanding finite population. Proc Natl Acad Sci U S A (1974) 1.52
Prevention of hepatocellular carcinoma in patients with chronic active hepatitis C and cirrhosis. Lancet (2001) 1.52
TOM1, an Arabidopsis gene required for efficient multiplication of a tobamovirus, encodes a putative transmembrane protein. Proc Natl Acad Sci U S A (2000) 1.52