Published in Biotechnol Prog on March 24, 2007
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. Nat Biotechnol (2013) 1.36
Advances in recombinant antibody manufacturing. Appl Microbiol Biotechnol (2016) 0.85
Enhancement of antibody production by the addition of Coenzyme-Q(10). Cytotechnology (2011) 0.81
Improvement of recombinant protein production by an anti-apoptotic protein from hemolymph of Lonomia obliqua. Cytotechnology (2010) 0.75
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol (2011) 2.87
A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution. Curr Opin Biotechnol (2008) 1.69
A mathematical model of N-linked glycosylation. Biotechnol Bioeng (2005) 1.42
Controlling N-linked glycan site occupancy. Biochim Biophys Acta (2005) 1.42
Enhanced transient recombinant protein production in CHO cells through the co-transfection of the product gene with Bcl-xL. Biotechnol J (2014) 1.38
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. Nat Biotechnol (2013) 1.36
Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines. Glycoconj J (2004) 1.27
Structure and synthesis of polyisoprenoids used in N-glycosylation across the three domains of life. Biochim Biophys Acta (2009) 1.17
Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL. Protein Expr Purif (2009) 1.09
Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org. Biotechnol Bioeng (2011) 1.08
Links between metabolism and apoptosis in mammalian cells: applications for anti-apoptosis engineering. Metab Eng (2007) 1.07
Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool. Biotechnol Bioeng (2014) 1.04
A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data. Glycobiology (2009) 1.01
The emerging CHO systems biology era: harnessing the 'omics revolution for biotechnology. Curr Opin Biotechnol (2013) 0.98
Life and death in mammalian cell culture: strategies for apoptosis inhibition. Trends Biotechnol (2004) 0.97
The effect of mixotrophy on microalgal growth, lipid content, and expression levels of three pathway genes in Chlorella sorokiniana. Appl Microbiol Biotechnol (2011) 0.97
Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them. Biochemistry (2003) 0.96
Production and N-glycan analysis of secreted human erythropoietin glycoprotein in stably transfected Drosophila S2 cells. Biotechnol Bioeng (2005) 0.95
False positive reactivity of recombinant, diagnostic, glycoproteins produced in High Five insect cells: effect of glycosylation. J Immunol Methods (2007) 0.93
Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnol Bioeng (2004) 0.93
An improved colony PCR procedure for genetic screening of Chlorella and related microalgae. Biotechnol Lett (2011) 0.91
Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures. Biotechnol Bioeng (2006) 0.91
Expression of a functional Drosophila melanogaster N-acetylneuraminic acid (Neu5Ac) phosphate synthase gene: evidence for endogenous sialic acid biosynthetic ability in insects. Glycobiology (2002) 0.91
Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins. Biotechnol Bioeng (2011) 0.90
Humanization of lepidopteran insect-cell-produced glycoproteins. Acc Chem Res (2003) 0.90
Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells. Biotechnol Bioeng (2007) 0.89
Cellular trafficking and photochemical internalization of cell penetrating peptide linked cargo proteins: a dual fluorescent labeling study. Bioconjug Chem (2011) 0.89
Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants. Biotechnol Bioeng (2002) 0.89
Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L). Biotechnol Bioeng (2008) 0.89
GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. J Proteome Res (2011) 0.88
Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation. Biochemistry (2005) 0.87
A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. Metab Eng (2003) 0.86
Purification, characterization, and cloning of a Spodoptera frugiperda Sf9 beta-N-acetylhexosaminidase that hydrolyzes terminal N-acetylglucosamine on the N-glycan core. J Biol Chem (2006) 0.85
Integration of the transcriptome and glycome for identification of glycan cell signatures. PLoS Comput Biol (2013) 0.85
Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival. J Bioenerg Biomembr (2014) 0.85
Physiological evaluation of a new Chlorella sorokiniana isolate for its biomass production and lipid accumulation in photoautotrophic and heterotrophic cultures. Biotechnol Bioeng (2012) 0.84
Study of caspase inhibitors for limiting death in mammalian cell culture. Biotechnol Bioeng (2003) 0.84
Expression of a functional Drosophila melanogaster CMP-sialic acid synthetase. Differential localization of the Drosophila and human enzymes. J Biol Chem (2006) 0.84
Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells. Biotechnol Bioeng (2005) 0.84
Complex-type biantennary N-glycans of recombinant human transferrin from Trichoplusia ni insect cells expressing mammalian [beta]-1,4-galactosyltransferase and [beta]-1,2-N-acetylglucosaminyltransferase II. Glycobiology (2002) 0.83
Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture. Biotechnol Bioeng (2009) 0.83
Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells. Biotechnol Prog (2009) 0.83
Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation. Protein Eng Des Sel (2011) 0.82
E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells. J Biotechnol (2008) 0.81
Transient and stable expression of the neurotensin receptor NTS1: a comparison of the baculovirus-insect cell and the T-REx-293 expression systems. PLoS One (2013) 0.81
Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture. Biotechnol Bioeng (2007) 0.81
Polyprenyl lipid synthesis in mammalian cells expressing human cis-prenyl transferase. Biochem Biophys Res Commun (2005) 0.80
Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen. Stem Cells Dev (2010) 0.80
Combining high-throughput screening of caspase activity with anti-apoptosis genes for development of robust CHO production cell lines. Biotechnol Prog (2010) 0.79
An improved in vitro and in vivo Sindbis virus expression system through host and virus engineering. Virus Res (2009) 0.79
Protein and genome evolution in Mammalian cells for biotechnology applications. Mol Biotechnol (2009) 0.79
N-glycan structures of human transferrin produced by Lymantria dispar (gypsy moth) cells using the LdMNPV expression system. Glycobiology (2003) 0.79
An HPLC-MALDI MS method for N-glycan analyses using smaller size samples: application to monitor glycan modulation by medium conditions. Glycoconj J (2009) 0.78
Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures. Biotechnol Bioeng (2007) 0.78
Antigen retrieval to improve the immunocytochemistry detection of sigma-1 receptors and ER chaperones. Histochem Cell Biol (2011) 0.78
Coupling enrichment methods with proteomics for understanding and treating disease. Proteomics Clin Appl (2015) 0.78
Bioprospecting of microalgae for integrated biomass production and phytoremediation of unsterilized wastewater and anaerobic digestion centrate. Appl Microbiol Biotechnol (2015) 0.78
Feast or famine: autophagy control and engineering in eukaryotic cell culture. Curr Opin Biotechnol (2008) 0.78
The effect of iron on growth, lipid accumulation, and gene expression profile of the freshwater microalga Chlorella sorokiniana. Appl Microbiol Biotechnol (2014) 0.77
DmSAS is required for sialic acid biosynthesis in cultured Drosophila third instar larvae CNS neurons. ACS Chem Biol (2011) 0.77
Achieving high throughput sequencing of a cDNA library utilizing an alternative protocol for the bench top next-generation sequencing system. J Microbiol Methods (2012) 0.76
Tat-tetanus toxin fragment C: a novel protein delivery vector and its use with photochemical internalization. J Drug Target (2013) 0.76
Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines. Biotechnol Appl Biochem (2012) 0.76
Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells. Biochem Biophys Res Commun (2010) 0.75
Strategies for Engineering Protein N-Glycosylation Pathways in Mammalian Cells. Methods Mol Biol (2015) 0.75
Engineering Sialic Acid Synthesis Ability in Insect Cells. Methods Mol Biol (2015) 0.75
Mineral and non-carbon nutrient utilization and recovery during sequential phototrophic-heterotrophic growth of lipid-rich algae. Appl Microbiol Biotechnol (2014) 0.75
Metabolic engineering II. Eukaryotic systems. Biotechnol Bioeng (2002) 0.75
Controlling apoptosis to optimize yields of proteins from mammalian cells. Methods Mol Biol (2012) 0.75