PubRank

Benjamin T Kile

Author PubWeight™ 60.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Programmed anuclear cell death delimits platelet life span. Cell 2007 5.98
2 The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells. Nat Immunol 2008 3.07
3 NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. Immunity 2012 2.14
4 The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments. Immunity 2012 1.89
5 Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome. Blood 2009 1.79
6 Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function. Blood 2009 1.74
7 Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia. Blood 2011 1.69
8 Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice. Blood 2011 1.69
9 Mutation discovery in mice by whole exome sequencing. Genome Biol 2011 1.69
10 Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function. Blood 2012 1.67
11 Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically. Cancer Cell 2013 1.67
12 Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. Blood 2012 1.57
13 Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood 2011 1.56
14 A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis. PLoS Genet 2008 1.40
15 A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor". J Immunol 2007 1.34
16 ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev 2011 1.30
17 Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets. J Exp Med 2011 1.27
18 Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage. Proc Natl Acad Sci U S A 2009 1.18
19 Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proc Natl Acad Sci U S A 2006 1.09
20 Critical roles for c-Myb in lymphoid priming and early B-cell development. Blood 2010 1.09
21 Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradation. J Biol Chem 2006 1.05
22 Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant. Blood 2009 1.04
23 Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development. Mol Cell Biol 2007 1.03
24 ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. Cell Metab 2013 1.02
25 The role of the ETS factor erg in zebrafish vasculogenesis. Mech Dev 2008 1.02
26 Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease. Proc Natl Acad Sci U S A 2013 0.98
27 Platelet senescence is regulated by an internal timer, not damage inflicted by hits. Blood 2010 0.97
28 Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice. PLoS One 2013 0.96
29 Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A 2012 0.95
30 Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice. Blood 2008 0.95
31 Description of a novel mutation leading to MYH9-related disease. Thromb Res 2008 0.94
32 Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion. Blood 2010 0.90
33 ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level. Blood Cells Mol Dis 2012 0.88
34 Apoptotic processes in megakaryocytes and platelets. Semin Hematol 2010 0.88
35 A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency. J Immunol 2009 0.88
36 Mutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopenia. Blood 2009 0.86
37 Platelet life span and apoptosis. Methods Mol Biol 2012 0.84
38 Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets. Blood 2012 0.83
39 Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A 2013 0.82
40 MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke. PLoS One 2013 0.82
41 Two ENU-induced alleles of Atp2b2 cause deafness in mice. PLoS One 2013 0.81
42 MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication. PLoS Pathog 2013 0.81
43 Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia. J Immunol 2011 0.80
44 An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation. Blood 2011 0.79
45 A model for studying the hemostatic consumption or destruction of platelets. PLoS One 2013 0.78
46 Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia. Am J Hematol 2014 0.77
47 Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain. Proc Natl Acad Sci U S A 2011 0.75
48 Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest 2017 0.75
49 Probabilistic analysis of recessive mutagenesis screen strategies. Mamm Genome 2007 0.75
50 Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263). Blood 2013 0.75
51 Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. Proc Natl Acad Sci U S A 2015 0.75